Detailed information for compound 824830

Basic information

Technical information
  • TDR Targets ID: 824830
  • Name: 2-[3-(4-fluorobenzoyl)-6-methyl-4-oxoquinolin -1-yl]-N-(4-methoxyphenyl)acetamide
  • MW: 444.454 | Formula: C26H21FN2O4
  • H donors: 1 H acceptors: 3 LogP: 4.59 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)NC(=O)Cn1cc(C(=O)c2ccc(cc2)F)c(=O)c2c1ccc(c2)C
  • InChi: 1S/C26H21FN2O4/c1-16-3-12-23-21(13-16)26(32)22(25(31)17-4-6-18(27)7-5-17)14-29(23)15-24(30)28-19-8-10-20(33-2)11-9-19/h3-14H,15H2,1-2H3,(H,28,30)
  • InChiKey: PSMAWYLFWBAOLB-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[3-(4-fluorobenzoyl)-6-methyl-4-oxo-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-[(4-fluorophenyl)-oxomethyl]-6-methyl-4-oxo-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-(4-fluorobenzoyl)-4-keto-6-methyl-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-(4-fluorophenyl)carbonyl-6-methyl-4-oxo-quinolin-1-yl]-N-(4-methoxyphenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.01 0.1265 0.1263
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0077 0.092 0.1102
Plasmodium falciparum proteasome subunit beta type-5 0.0573 0.8326 1
Echinococcus granulosus neuropeptide s receptor 0.0501 0.7251 0.7303
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0077 0.092 0.1102
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0265 0.3726 0.3725
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.0485 0.0482
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0233 0.3247 0.3245
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.01 0.1265 0.1517
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Trypanosoma brucei ATP-dependent protease subunit HslV 0.01 0.1265 0.131
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Plasmodium vivax proteasome subunit alpha type-7, putative 0.01 0.1265 0.1517
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0661 0.9641 1
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) proteasome subunit beta type 2 0.0233 0.3247 0.3362
Onchocerca volvulus 0.0265 0.3726 0.4531
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0561 0.8148 0.8208
Echinococcus granulosus proteasome subunit beta t family 0.01 0.1265 0.1272
Echinococcus multilocularis nuclear receptor nhr 48 0.0265 0.3726 0.3725
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.0485 0.0482
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0561 0.8148 0.8148
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0007
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Brugia malayi Nuclear hormone receptor E75 0.0265 0.3726 0.3859
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.0485 0.0482
Loa Loa (eye worm) phospholipase D 0.0019 0.0063 0.0055
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.01 0.1265 0.1263
Onchocerca volvulus 0.0047 0.0485 0.0521
Leishmania major proteasome beta 2 subunit, putative 0.0233 0.3247 0.3366
Brugia malayi nuclear receptor NHR-88 0.0265 0.3726 0.3859
Onchocerca volvulus 0.0047 0.0485 0.0521
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0561 0.8148 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.0485 0.0493
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.01 0.1265 0.1517
Brugia malayi AKH receptor 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0573 0.8326 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Brugia malayi Melatonin receptor type 1A 0.0047 0.0485 0.0493
Schistosoma mansoni cpg binding protein 0.0028 0.02 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.2404 0.1614
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Entamoeba histolytica proteasome subunit beta type 1, putative 0.037 0.5304 0.6369
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Echinococcus granulosus FTZ F1 alpha 0.0561 0.8148 0.8208
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0077 0.092 0.1094
Plasmodium vivax proteasome subunit beta type-2, putative 0.0233 0.3247 0.3898
Leishmania major proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Giardia lamblia 20S proteasome alpha subunit 3 0.01 0.1265 0.1519
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0296 0.42 0.4198
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.0485 0.0482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit beta type-7, putative 0.01 0.1265 0.1517
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0511 0.052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Echinococcus multilocularis phospholipase D1 0.0101 0.1291 0.1288
Plasmodium falciparum proteasome subunit beta type-4 0.01 0.1265 0.1517
Echinococcus multilocularis cpg binding protein 0.003 0.0224 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0561 0.8148 0.8451
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.0485 0.0486
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Brugia malayi neuropeptide F receptor 0.0047 0.0485 0.0493
Brugia malayi proteasome subunit alpha type 2 0.01 0.1265 0.1303
Brugia malayi nuclear hormone receptor 0.0561 0.8148 0.8451
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0561 0.8148 0.8148
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0561 0.8148 0.8208
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.01 0.1265 0.1517
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0276
Plasmodium vivax proteasome subunit alpha type-5, putative 0.01 0.1265 0.1517
Plasmodium vivax proteasome subunit alpha type-4, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi 20S proteasome subunit 0.0233 0.3247 0.3366
Brugia malayi photoreceptor-specific nuclear receptor 0.0561 0.8148 0.8451
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.01 0.1265 0.131
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.0485 0.0482
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii peptidase, T1 family protein 0.01 0.1265 0.1517
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0077 0.092 0.1102
Brugia malayi tailless protein 0.0265 0.3726 0.3859
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0561 0.8148 0.8451
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.3576 0.3703
Brugia malayi Serotonin receptor 0.0047 0.0485 0.0493
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Onchocerca volvulus 0.0047 0.0485 0.0521
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0561 0.8148 0.8451
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0561 0.8148 0.8148
Leishmania major proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0077 0.092 0.1102
Echinococcus granulosus neuropeptide receptor A26 0.0501 0.7251 0.7303
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.0485 0.0486
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit alpha type, putative 0.01 0.1265 0.1517
Brugia malayi follicle stimulating hormone receptor 0.0047 0.0485 0.0493
Brugia malayi conserved hypotetical protein 0.0265 0.3726 0.3859
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0085 0.1048 0.1257
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0077 0.092 0.1102
Plasmodium vivax proteasome subunit beta type-5, putative 0.0573 0.8326 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0265 0.3726 0.3859
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0077 0.092 0.1094
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0561 0.8148 0.8451
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0265 0.3726 0.3725
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0485 0.0486
Brugia malayi GnHR receptor homolog 0.0047 0.0485 0.0493
Schistosoma mansoni retinoic acid receptor RXR 0.0658 0.9598 0.9598
Echinococcus granulosus cpg binding protein 0.003 0.0224 0.0223
Echinococcus granulosus cytochrome P450 2K1 0.0077 0.092 0.0924
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0011
Leishmania major proteasome beta 5 subunit, putative 0.0573 0.8326 0.8636
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0036 0.0322 0.0324
Echinococcus granulosus serotonin receptor 0.0047 0.0485 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Onchocerca volvulus Protein ultraspiracle homolog 0.0561 0.8148 1
Loa Loa (eye worm) hypothetical protein 0.0661 0.9641 1
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0279 0.028
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.01 0.1265 0.131
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.01 0.1265 0.0466
Toxoplasma gondii proteasome subunit 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0561 0.8148 0.8451
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0077 0.092 0.1102
Loa Loa (eye worm) nuclear receptor NHR-67 0.0265 0.3726 0.3859
Echinococcus granulosus orexin receptor type 2 0.0047 0.0485 0.0486
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0077 0.092 0.1102
Echinococcus multilocularis microtubule associated protein 2 0.068 0.9927 0.9927
Echinococcus granulosus thyroid hormone receptor alpha 0.0265 0.3726 0.3752
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0077 0.092 0.1094
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Proteasome subunit alpha type 1 0.01 0.1265 0.1303
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.0485 0.0482
Leishmania major cardiolipin synthetase, putative 0.0016 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0561 0.8148 0.8451
Brugia malayi Proteasome subunit alpha type 7-1 0.01 0.1265 0.1303
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0561 0.8148 0.8148
Brugia malayi Protein K4 0.0016 0.002 0.0011
Echinococcus multilocularis GPCR, family 2 0.0016 0.001 0.0007
Trypanosoma brucei proteasome beta 6 subunit 0.037 0.5304 0.55
Echinococcus multilocularis orexin receptor type 2 0.0047 0.0485 0.0482
Echinococcus multilocularis phospholipase D 0.009 0.1114 0.1112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Giardia lamblia 20S proteasome alpha subunit 6 0.01 0.1265 0.1519
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0561 0.8148 0.8451
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.01 0.1265 0.1263
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus phospholipase D1 0.0101 0.1291 0.1298
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.01 0.1265 0.1509
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0573 0.8326 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0077 0.092 0.1102
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0077 0.092 0.1094
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Plasmodium falciparum proteasome subunit beta type-1, putative 0.037 0.5304 0.6369
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus Nuclear hormone receptor HR96 0.0265 0.3726 0.3752
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0561 0.8148 0.8451
Loa Loa (eye worm) cytochrome P450 family protein 0.0077 0.092 0.0945
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) proteasome subunit alpha type 1 0.01 0.1265 0.1303
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.0485 0.0486
Echinococcus granulosus proteasome subunit beta type 7 0.01 0.1265 0.1272
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Brugia malayi Cytochrome P450 family protein 0.0113 0.1464 0.151
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) proteasome subunit alpha type 2 0.01 0.1265 0.1303
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0233 0.3247 0.3269
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.037 0.5304 0.5302
Schistosoma mansoni thyroid hormone receptor 0.0685 1 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.01 0.1265 0.1303
Trypanosoma brucei Emopamil binding protein, putative 0.0123 0.162 0.1678
Echinococcus multilocularis proteasome subunit beta type 7 0.01 0.1265 0.1263
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0482
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.1464 0.151
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0485 0.0486
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0362 0.5176 0.5175
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0077 0.092 0.1102
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.01 0.1265 0.1263
Brugia malayi CXXC zinc finger family protein 0.0028 0.02 0.0198
Loa Loa (eye worm) steroid hormone receptor 0.0561 0.8148 0.8451
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.02 0.0198
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.01 0.1265 0.131
Brugia malayi ecdysteroid receptor 0.0561 0.8148 0.8451
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0561 0.8148 0.8208
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.002 0.0021
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.0485 0.0486
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.0485 0.0482
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.001 0.0009
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0573 0.8326 1
Giardia lamblia Proteasome subunit beta type 9 precursor 0.01 0.1265 0.1519
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0561 0.8148 0.8148
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.01 0.1265 0.1517
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0077 0.092 0.1094
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.01 0.1265 0.131
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0485 0.0493
Brugia malayi 20S proteasome alpha5 subunit 0.01 0.1265 0.1303
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi proteasome subunit alpha type 3 0.01 0.1265 0.1303
Schistosoma mansoni thyroid hormone receptor 0.0685 1 1
Echinococcus multilocularis 0.0077 0.092 0.0918
Schistosoma mansoni RAR-like nuclear receptor 0.0561 0.8148 0.8148
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0233 0.3247 0.2808
Loa Loa (eye worm) hypothetical protein 0.0338 0.4819 0.4993
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Brugia malayi larval opioid receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni cpg binding protein 0.003 0.0224 0.0222
Giardia lamblia Proteasome subunit beta type 2 0.0233 0.3247 0.39
Trypanosoma cruzi cardiolipin synthetase, putative 0.0035 0.0305 0.0314
Brugia malayi Nuclear hormone receptor-like 1 0.0561 0.8148 0.8451
Echinococcus multilocularis Proteasome, subunit alpha beta 0.01 0.1265 0.1263
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0485 0.0493
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0009
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.01 0.1265 0.1517
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.0485 0.0493
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Onchocerca volvulus Notchless protein homolog 0.01 0.1265 0.1486
Echinococcus multilocularis phospholipase d3 0.0019 0.0063 0.0061
Schistosoma mansoni hypothetical protein 0.0167 0.227 0.2268
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.0485 0.0493
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.0485 0.0493
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0485 0.0493
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.0485 0.0482
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0007
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0063 0.0063
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.01 0.1265 0.131
Brugia malayi G-protein coupled receptor 0.0047 0.0485 0.0493
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0233 0.3247 0.3245
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0077 0.092 0.1094
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.01 0.1265 0.1263
Schistosoma mansoni histamine h1 receptor 0.0047 0.0485 0.0482
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0485 0.0482
Echinococcus granulosus proteasome subunit beta type 6 0.01 0.1265 0.1272
Echinococcus granulosus GPCR family 2 0.0016 0.001 0.0007
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0265 0.3726 0.3859
Trypanosoma brucei proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0485 0.0493
Giardia lamblia 20S proteasome alpha subunit 2 0.01 0.1265 0.1519
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0561 0.8148 0.8148
Schistosoma mansoni hypothetical protein 0.0035 0.0307 0.0304
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.0485 0.0486
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0661 0.9641 1
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0511 0.052
Brugia malayi hypothetical protein 0.0296 0.42 0.4351
Plasmodium vivax proteasome subunit alpha type-2, putative 0.01 0.1265 0.1517
Echinococcus granulosus Proteasome subunit alpha type 7 0.01 0.1265 0.1272
Loa Loa (eye worm) hypothetical protein 0.0063 0.0714 0.0731
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0561 0.8148 0.8451
Trypanosoma brucei cardiolipin synthetase 0.0035 0.0305 0.0314
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0561 0.8148 0.8451
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus multilocularis sex peptide receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0296 0.42 0.4351
Schistosoma mansoni hypothetical protein 0.0403 0.5794 0.5792
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0233 0.3247 0.3366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni hypothetical protein 0.0167 0.227 0.2268
Schistosoma mansoni myosin xvIII 0.0047 0.0485 0.0482
Loa Loa (eye worm) proteasome subunit beta type 1 0.037 0.5304 0.5497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.01 0.1265 0.1517
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni steroid hormone receptor ad4bp 0.0561 0.8148 0.8148
Entamoeba histolytica phospholipase D, putative 0.0101 0.1291 0.1548
Brugia malayi putative neuropeptide receptor 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.01 0.1265 0.1263
Giardia lamblia Proteasome subunit beta type 3 0.01 0.1265 0.1519
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.0485 0.0521
Leishmania major proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi Emopamil binding protein, putative 0.0123 0.162 0.1678
Brugia malayi sulfakinin receptor protein 0.0047 0.0485 0.0493
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Entamoeba histolytica proteasome subunit beta type 3, putative 0.01 0.1265 0.1517
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus granulosus 20S proteasome subunit alpha 6 0.01 0.1265 0.1272
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Echinococcus granulosus g-protein coupled receptor 0.0047 0.0485 0.0486
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0561 0.8148 0.8148
Loa Loa (eye worm) CYP4Cod1 0.0113 0.1464 0.151
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.01 0.1265 0.1517
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni zinc finger protein 0.0265 0.3726 0.3725
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0077 0.092 0.1102
Brugia malayi hypothetical protein 0.0016 0.002 0.0011
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.0485 0.0482
Brugia malayi proteasome subunit beta type 3 0.01 0.1265 0.1303
Plasmodium vivax proteasome subunit beta type-1, putative 0.037 0.5304 0.6369
Leishmania major cytochrome p450-like protein 0.0113 0.1464 0.1516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0265 0.3726 0.3725
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0561 0.8148 0.8451
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0658 0.9598 0.9669
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0573 0.8326 0.8634
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0233 0.3247 0.3898
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0085 0.1048 0.1078
Loa Loa (eye worm) DR-78 0.0265 0.3726 0.3859
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0485 0.0482
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0511 0.052
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Onchocerca volvulus 0.0265 0.3726 0.4531
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Onchocerca volvulus 0.0123 0.162 0.1925
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.01 0.1265 0.1517
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0485 0.0486
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Chlamydia trachomatis phospholipase D superfamily protein 0.0016 0.002 0.5
Brugia malayi ORL1-like opioid receptor 0.0047 0.0485 0.0493
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0233 0.3247 0.3245
Echinococcus multilocularis somatostatin receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis FTZ F1 alpha 0.0561 0.8148 0.8148
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis ecdysone induced protein 78C 0.0561 0.8148 0.8148
Onchocerca volvulus Bile acid receptor homolog 0.0561 0.8148 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Onchocerca volvulus 0.0063 0.0714 0.0805
Echinococcus granulosus proteasome subunit alpha type 6 0.01 0.1265 0.1272
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.01 0.1265 0.1517
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Brugia malayi Cytochrome P450 family protein 0.0077 0.092 0.0945
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.037 0.5304 0.5302
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.01 0.1265 0.131
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.01 0.1265 0.1263
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Schistosoma mansoni hypothetical protein 0.0077 0.092 0.0918
Giardia lamblia Proteasome subunit beta type 7 precursor 0.01 0.1265 0.1519
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.01 0.1265 0.1517
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0561 0.8148 0.8451
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0485 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Schistosoma mansoni nuclear receptor 0.0265 0.3726 0.3725
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0561 0.8148 0.8451
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0307 0.0304
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0077 0.092 0.1102
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0077 0.092 0.0952
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Brugia malayi ecdysone receptor 0.0265 0.3726 0.3859
Trypanosoma cruzi Emopamil binding protein, putative 0.0123 0.162 0.1678
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.001 0.0008
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) nuclear hormone receptor 0.0265 0.3726 0.3859
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0047 0.0485 0.0493
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Schistosoma mansoni cpg binding protein 0.003 0.0224 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Brugia malayi proteasome subunit alpha type 6 0.01 0.1265 0.1303
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0578 0.0691
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0066 0.0763 0.0782
Schistosoma mansoni cytochrome P450 0.0077 0.092 0.0918
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0077 0.092 0.1094
Brugia malayi Cytochrome P450 family protein 0.0077 0.092 0.0945
Brugia malayi Proteasome A-type and B-type family protein 0.0573 0.8326 0.8634
Onchocerca volvulus 0.0047 0.0485 0.0521
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.01 0.1265 0.1517
Leishmania major proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Brugia malayi neuropeptide F receptor 0.0047 0.0485 0.0493
Trypanosoma cruzi cytochrome P450, putative 0.0113 0.1464 0.1516
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis proteasome subunit alpha type 2 0.01 0.1265 0.1263
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0077 0.092 0.1102
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0561 0.8148 0.8148
Plasmodium vivax proteasome subunit alpha type-1, putative 0.01 0.1265 0.1517
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0485 0.0482
Leishmania major C-8 sterol isomerase-like protein 0.0661 0.9641 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0265 0.3726 0.3752
Onchocerca volvulus 0.0047 0.0485 0.0521
Onchocerca volvulus 0.0047 0.0485 0.0521
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.01 0.1265 0.1517
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.0485 0.0493
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0561 0.8148 0.8451
Echinococcus granulosus neuropeptide receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Plasmodium falciparum proteasome subunit beta type-3, putative 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.01 0.1265 0.1517
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0482
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis proteasome (prosome, macropain) 0.0573 0.8326 0.8325
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.01 0.1265 0.1263
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.0485 0.0486
Leishmania major proteasome beta 7 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni coup transcription factor 0.0561 0.8148 0.8148
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0077 0.092 0.1094
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.0485 0.0493
Brugia malayi GYF domain containing protein 0.0063 0.0714 0.0731
Onchocerca volvulus 0.0047 0.0485 0.0521
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus microtubule associated protein 2 0.068 0.9927 1
Plasmodium falciparum proteasome subunit beta type-6, putative 0.01 0.1265 0.1517
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.1464 0.151
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0561 0.8148 0.8451
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.01 0.1265 0.1517
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0561 0.8148 0.8148
Plasmodium vivax proteasome subunit beta type-4, putative 0.01 0.1265 0.1517
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.0485 0.0493
Echinococcus granulosus dnaJ subfamily B 0.0403 0.5794 0.5835
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0077 0.092 0.1094
Loa Loa (eye worm) proteasome subunit alpha type 3 0.01 0.1265 0.1303
Trypanosoma brucei cytochrome P450, putative 0.0113 0.1464 0.1516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.01 0.1265 0.1517
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.002 0.0021
Brugia malayi cytochrome P450 0.0077 0.092 0.0945
Echinococcus granulosus nuclear receptor nhr 48 0.0265 0.3726 0.3752
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0486
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0077 0.092 0.0952
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Serotonin receptor 0.0047 0.0485 0.0493
Echinococcus granulosus neuropeptide receptor 0.0047 0.0485 0.0486
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.01 0.1265 0.1517
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0265 0.3726 0.3725
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0077 0.092 0.1102
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0007
Schistosoma mansoni phospholipase D 0.0101 0.1291 0.1288
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0077 0.092 0.1094
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0077 0.092 0.1094
Schistosoma mansoni nuclear hormone receptor 0.0561 0.8148 0.8148
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.037 0.5304 0.572
Leishmania major proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Leishmania major cytochrome p450-like protein 0.0077 0.092 0.0952
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Plasmodium vivax proteasome subunit beta type-7, putative 0.01 0.1265 0.1517
Trypanosoma brucei proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0265 0.3726 0.4531
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0307 0.0304
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Echinococcus granulosus allatostatin A receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis geminin 0.0167 0.227 0.2268
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0573 0.8326 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.001 0.0009
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0233 0.3247 0.3898
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni nuclear hormone receptor 0.0265 0.3726 0.3725
Brugia malayi hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0265 0.3726 0.3752
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0077 0.092 0.1094
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Brugia malayi proteasome subunit alpha type 4 0.01 0.1265 0.1303
Giardia lamblia 20S proteasome alpha subunit 1 0.01 0.1265 0.1519
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.0485 0.0493
Brugia malayi Steroid receptor seven-up type 2 0.0561 0.8148 0.8451
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0265 0.3726 0.3752
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0296 0.42 0.4198
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0561 0.8148 0.8451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0561 0.8148 0.8451
Leishmania major hypothetical protein, conserved 0.0123 0.162 0.1678
Giardia lamblia Proteasome subunit beta type 1 0.037 0.5304 0.637
Loa Loa (eye worm) proteasome subunit alpha type 6 0.01 0.1265 0.1303
Brugia malayi nuclear receptor NHR-88 0.0561 0.8148 0.8451
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.01 0.1265 0.1517
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0573 0.8326 0.8325
Echinococcus granulosus proteasome subunit alpha type 2 0.01 0.1265 0.1272
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.01 0.1265 0.1517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.0485 0.0493
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus phospholipase D 0.009 0.1114 0.112
Entamoeba histolytica phospholipase D, putative 0.0101 0.1291 0.1548
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0007
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Loa Loa (eye worm) hypothetical protein 0.0085 0.1048 0.1078
Mycobacterium ulcerans proteasome PrcA 0.01 0.1265 0.1517
Brugia malayi Nuclear hormone receptor E75 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0049 0.0511 0.052
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.0485 0.0482
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0077 0.092 0.1102
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0561 0.8148 0.8451
Echinococcus multilocularis subfamily T1A non peptidase ue 0.01 0.1265 0.1263
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.0485 0.0486
Leishmania major proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0077 0.092 0.1102
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0077 0.092 0.1094
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0486
Echinococcus granulosus proteasome prosome macropain subunit beta 0.037 0.5304 0.5341
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0077 0.092 0.1094
Brugia malayi Nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.001 0.0008
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0077 0.092 0.1102
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Toxoplasma gondii cytochrome p450 superfamily protein 0.0077 0.092 0.1102
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.0485 0.0482
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0113 0.1464 0.1756
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0035 0.0305 0.0364
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.01 0.1265 0.1263
Echinococcus granulosus proteasome prosome macropain 0.0573 0.8326 0.8386
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.0485 0.0493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0077 0.092 0.1094
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.0485 0.0482
Onchocerca volvulus 0.0047 0.0485 0.0521
Echinococcus granulosus hypothetical protein 0.0047 0.0485 0.0486
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0485 0.0482
Brugia malayi Nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Leishmania major cytochrome p450-like protein 0.0077 0.092 0.0952
Plasmodium vivax proteasome subunit alpha type-6, putative 0.01 0.1265 0.1517
Brugia malayi proteasome subunit alpha type 1 0.01 0.1265 0.1303
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0077 0.092 0.1094
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium ulcerans proteasome PrcB 0.0573 0.8326 1
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0233 0.3247 0.3366
Brugia malayi hypothetical protein 0.0035 0.0307 0.0309
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis proteasome subunit beta type 6 0.01 0.1265 0.1263
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0077 0.092 0.1102
Schistosoma mansoni nuclear receptor nhr-48 0.0265 0.3726 0.3725
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0233 0.3247 0.2808
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0265 0.3726 0.3725
Brugia malayi Dopamine receptor protein 1 0.0047 0.0485 0.0493
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus granulosus fmrfamide receptor 0.0047 0.0485 0.0486
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.01 0.1265 1
Loa Loa (eye worm) cytochrome P450 0.0077 0.092 0.0945
Giardia lamblia Proteasome subunit beta type 4 precursor 0.01 0.1265 0.1519
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.227 0.2729
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0561 0.8148 0.8208
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Echinococcus granulosus phospholipase d3 0.0019 0.0063 0.0061
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.0485 0.0482
Echinococcus multilocularis allatostatin A receptor 0.0047 0.0485 0.0482
Echinococcus granulosus subfamily T1A non peptidase ue 0.01 0.1265 0.1272
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0077 0.092 0.1102
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Toxoplasma gondii proteasome subunit beta type 1, putative 0.037 0.5304 0.6369
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.01 0.1265 0.1263
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0296 0.42 0.4198
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0573 0.8326 1
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0077 0.092 0.1094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0561 0.8148 0.8451
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Brugia malayi G-protein coupled receptor 0.0047 0.0485 0.0493
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit alpha1, putative 0.01 0.1265 0.1517
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.1629 0.1627
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0077 0.092 0.1102
Toxoplasma gondii proteasome subunit beta type, putative 0.0573 0.8326 1
Leishmania major proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Brugia malayi orphan nuclear receptor NR2E1 0.0265 0.3726 0.3859
Brugia malayi Phospholipase d protein 1 0.0101 0.1291 0.133
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Brugia malayi Phospholipase D. Active site motif family protein 0.0035 0.0305 0.0307
Brugia malayi proteasome subunit beta type 2 0.0233 0.3247 0.3362
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.002 0.0021
Onchocerca volvulus 0.0047 0.0485 0.0521
Trypanosoma brucei C-8 sterol isomerase, putative 0.0661 0.9641 1
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Echinococcus granulosus sex peptide receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.01 0.1265 0.1303
Brugia malayi hypothetical protein 0.0265 0.3726 0.3859
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0265 0.3726 0.3859
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0674 0.0671
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0077 0.092 0.1094
Loa Loa (eye worm) proteasome subunit beta type 3 0.01 0.1265 0.1303
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.0485 0.0486
Plasmodium vivax proteasome subunit beta type-3, putative 0.01 0.1265 0.1517
Schistosoma mansoni nuclear receptor 0.0265 0.3726 0.3725
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0307 0.0307
Brugia malayi nuclear receptor NHR-67 0.0265 0.3726 0.3859
Onchocerca volvulus 0.0561 0.8148 1
Echinococcus multilocularis neuropeptide receptor A26 0.0501 0.7251 0.725
Giardia lamblia 20S proteasome alpha subunit 5 0.01 0.1265 0.1519
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0561 0.8148 0.8148
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.002 0.0017
Trypanosoma cruzi cytochrome P450, putative 0.0113 0.1464 0.1516
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.01 0.1265 0.1263
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus ecdysone induced protein 78C 0.0561 0.8148 0.8208
Schistosoma mansoni adenoreceptor 0.0047 0.0485 0.0482
Chlamydia trachomatis phospholipase D superfamily protein 0.0016 0.002 0.5
Toxoplasma gondii heat shock protein hslv, putative 0.01 0.1265 0.1517
Brugia malayi Dopamine receptor 0.0047 0.0485 0.0493
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0059 0.0665 0.068
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0077 0.092 0.1102
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0063 0.0055
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.01 0.1265 0.1517
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0561 0.8148 0.8148
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis proteasome subunit alpha type 6 0.01 0.1265 0.1263
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Onchocerca volvulus 0.0028 0.02 0.0169
Schistosoma mansoni nuclear hormone receptor 0.0265 0.3726 0.3725
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.5794 0.5792
Loa Loa (eye worm) PAS-3 protein 0.01 0.1265 0.1303
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.01 0.1265 0.1517
Brugia malayi Cytochrome P450 family protein 0.0113 0.1464 0.151
Giardia lamblia 20S proteasome alpha subunit 7 0.01 0.1265 0.1519
Onchocerca volvulus 0.0047 0.0485 0.0521
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.01 0.1265 0.1517
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0265 0.3726 0.3725
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0077 0.092 0.1094
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0485 0.0482
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.3576 0.3703
Brugia malayi nuclear hormone receptor family member odr-7 0.0265 0.3726 0.3859
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.001 0.0008
Trypanosoma cruzi cardiolipin synthetase, putative 0.0035 0.0305 0.0314
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.0485 0.0493
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0561 0.8148 0.8148
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Plasmodium vivax proteasome subunit beta type-6, putative 0.01 0.1265 0.1517
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Brugia malayi proteasome subunit beta type 1 0.037 0.5304 0.5497
Onchocerca volvulus 0.0047 0.0485 0.0521
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.01 0.1265 0.1517
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0265 0.3726 0.4531
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.01 0.1265 0.1517
Brugia malayi Dopamine receptor protein 2 0.0047 0.0485 0.0493
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0561 0.8148 0.8451
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0233 0.3247 0.3898
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0485 0.0482
Brugia malayi G protein-coupled receptor 0.0047 0.0485 0.0493
Echinococcus granulosus Proteasome subunit alpha beta 0.01 0.1265 0.1272
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.0485 0.0521
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0485 0.0482
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.0485 0.0482
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Giardia lamblia 20S proteasome alpha subunit 4 0.01 0.1265 0.1519
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.01 0.1265 0.1272
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.0485 0.0493
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0561 0.8148 0.8208
Brugia malayi nuclear receptor RXR 0.0265 0.3726 0.3859
Schistosoma mansoni microtubule-associated protein tau 0.068 0.9927 0.9927
Loa Loa (eye worm) hypothetical protein 0.0066 0.0763 0.0782
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Trypanosoma brucei proteasome beta 7 subunit 0.01 0.1265 0.131
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.2404 0.1614
Toxoplasma gondii proteasome beta subunit 0.01 0.1265 0.1517
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.002 0.0021
Brugia malayi steroid hormone receptor 0.0561 0.8148 0.8451
Trypanosoma brucei proteasome alpha 7 subunit 0.01 0.1265 0.131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0077 0.092 0.1094
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0034 0.0279 0.028
Brugia malayi nuclear receptor RXR 0.0296 0.42 0.4351
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.0485 0.0482
Trypanosoma brucei cardiolipin synthetase, putative 0.0035 0.0305 0.0314
Trypanosoma brucei proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0124 0.1629 0.1627
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.01 0.1265 0.1263
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.01 0.1265 0.131
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.0485 0.0493
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0296 0.42 0.4229
Plasmodium vivax proteasome subunit alpha type-3, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Leishmania major proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.1629 0.1639
Echinococcus multilocularis neuropeptide s receptor 0.0501 0.7251 0.725
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.0485 0.0493
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.01 0.1265 0.1272
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Echinococcus granulosus geminin 0.0167 0.227 0.2285
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0561 0.8148 0.8208
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.0485 0.0482
Leishmania major proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Loa Loa (eye worm) hypothetical protein 0.0019 0.0063 0.0055
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0144 0.1924 0.1987
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0485 0.0486
Echinococcus granulosus somatostatin receptor 0.0047 0.0485 0.0486
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.0485 0.0482
Brugia malayi RE15519p 0.0047 0.0485 0.0493
Brugia malayi nuclear hormone receptor 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis serotonin receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis serotonin receptor 0.0047 0.0485 0.0482
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.0485 0.0486
Onchocerca volvulus 0.0047 0.0485 0.0521
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.