Detailed information for compound 824830

Basic information

Technical information
  • TDR Targets ID: 824830
  • Name: 2-[3-(4-fluorobenzoyl)-6-methyl-4-oxoquinolin -1-yl]-N-(4-methoxyphenyl)acetamide
  • MW: 444.454 | Formula: C26H21FN2O4
  • H donors: 1 H acceptors: 3 LogP: 4.59 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)NC(=O)Cn1cc(C(=O)c2ccc(cc2)F)c(=O)c2c1ccc(c2)C
  • InChi: 1S/C26H21FN2O4/c1-16-3-12-23-21(13-16)26(32)22(25(31)17-4-6-18(27)7-5-17)14-29(23)15-24(30)28-19-8-10-20(33-2)11-9-19/h3-14H,15H2,1-2H3,(H,28,30)
  • InChiKey: PSMAWYLFWBAOLB-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[3-(4-fluorobenzoyl)-6-methyl-4-oxo-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-[(4-fluorophenyl)-oxomethyl]-6-methyl-4-oxo-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-(4-fluorobenzoyl)-4-keto-6-methyl-1-quinolyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-(4-fluorophenyl)carbonyl-6-methyl-4-oxo-quinolin-1-yl]-N-(4-methoxyphenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0485 0.0482
Echinococcus granulosus proteasome subunit alpha type 2 0.01 0.1265 0.1272
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.0485 0.0486
Brugia malayi steroid hormone receptor 0.0561 0.8148 0.8451
Plasmodium vivax proteasome subunit beta type-2, putative 0.0233 0.3247 0.3898
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.1629 0.1639
Brugia malayi GYF domain containing protein 0.0063 0.0714 0.0731
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Brugia malayi Phospholipase D. Active site motif family protein 0.0035 0.0305 0.0307
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0077 0.092 0.1094
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.01 0.1265 0.1272
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0561 0.8148 0.8148
Echinococcus granulosus fmrfamide receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Loa Loa (eye worm) nuclear receptor NHR-67 0.0265 0.3726 0.3859
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0561 0.8148 0.8148
Trypanosoma cruzi Emopamil binding protein, putative 0.0123 0.162 0.1678
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.0485 0.0486
Plasmodium vivax proteasome subunit alpha type-6, putative 0.01 0.1265 0.1517
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.01 0.1265 0.131
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.01 0.1265 0.1517
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Onchocerca volvulus Bile acid receptor homolog 0.0561 0.8148 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Brugia malayi Nuclear hormone receptor E75 0.0265 0.3726 0.3859
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Brugia malayi Dopamine receptor protein 1 0.0047 0.0485 0.0493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Brugia malayi nuclear receptor RXR 0.0265 0.3726 0.3859
Trypanosoma cruzi Emopamil binding protein, putative 0.0123 0.162 0.1678
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.0485 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0573 0.8326 1
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.001 0.0008
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.037 0.5304 0.5302
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Schistosoma mansoni cpg binding protein 0.003 0.0224 0.0222
Echinococcus granulosus Proteasome subunit alpha beta 0.01 0.1265 0.1272
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Echinococcus multilocularis cpg binding protein 0.003 0.0224 0.0222
Giardia lamblia 20S proteasome alpha subunit 7 0.01 0.1265 0.1519
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0265 0.3726 0.3752
Onchocerca volvulus 0.0561 0.8148 1
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Echinococcus granulosus phospholipase D 0.009 0.1114 0.112
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Brugia malayi nuclear receptor NHR-88 0.0561 0.8148 0.8451
Brugia malayi Serotonin receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.1464 0.151
Schistosoma mansoni myosin xvIII 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.01 0.1265 0.1517
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0661 0.9641 1
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0573 0.8326 1
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.01 0.1265 0.1263
Onchocerca volvulus Notchless protein homolog 0.01 0.1265 0.1486
Chlamydia trachomatis phospholipase D superfamily protein 0.0016 0.002 0.5
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0511 0.052
Onchocerca volvulus 0.0047 0.0485 0.0521
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Giardia lamblia 20S proteasome alpha subunit 2 0.01 0.1265 0.1519
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0482
Brugia malayi proteasome subunit alpha type 1 0.01 0.1265 0.1303
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.0485 0.0493
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0279 0.028
Schistosoma mansoni thyroid hormone receptor 0.0685 1 1
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0233 0.3247 0.2808
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0573 0.8326 0.8325
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0019 0.0063 0.0055
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0077 0.092 0.1094
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.01 0.1265 0.1517
Plasmodium vivax proteasome subunit beta type-1, putative 0.037 0.5304 0.6369
Onchocerca volvulus 0.0265 0.3726 0.4531
Plasmodium vivax proteasome subunit beta type-7, putative 0.01 0.1265 0.1517
Schistosoma mansoni hypothetical protein 0.0124 0.1629 0.1627
Schistosoma mansoni retinoic acid receptor RXR 0.0658 0.9598 0.9598
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0077 0.092 0.1102
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.3576 0.3703
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.0485 0.0482
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.0485 0.0482
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus proteasome subunit beta type 6 0.01 0.1265 0.1272
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0561 0.8148 0.8451
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) proteasome subunit alpha type 6 0.01 0.1265 0.1303
Loa Loa (eye worm) hypothetical protein 0.0063 0.0714 0.0731
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0296 0.42 0.4229
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Echinococcus multilocularis sex peptide receptor 0.0047 0.0485 0.0482
Schistosoma mansoni cytochrome P450 0.0077 0.092 0.0918
Echinococcus granulosus neuropeptide receptor A26 0.0501 0.7251 0.7303
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0077 0.092 0.1102
Onchocerca volvulus 0.0047 0.0485 0.0521
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0658 0.9598 0.9669
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.01 0.1265 0.1517
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0077 0.092 0.1102
Echinococcus granulosus 20S proteasome subunit alpha 6 0.01 0.1265 0.1272
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi ORL1-like opioid receptor 0.0047 0.0485 0.0493
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Leishmania major C-8 sterol isomerase-like protein 0.0661 0.9641 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0763 0.0782
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.01 0.1265 0.131
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0077 0.092 0.1094
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0296 0.42 0.4198
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0573 0.8326 1
Onchocerca volvulus 0.0047 0.0485 0.0521
Leishmania major cytochrome p450-like protein 0.0077 0.092 0.0952
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0561 0.8148 0.8451
Brugia malayi Dopamine receptor 0.0047 0.0485 0.0493
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0561 0.8148 0.8148
Entamoeba histolytica phospholipase D, putative 0.0101 0.1291 0.1548
Leishmania major proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Brugia malayi tailless protein 0.0265 0.3726 0.3859
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.01 0.1265 0.1263
Loa Loa (eye worm) proteasome subunit alpha type 3 0.01 0.1265 0.1303
Echinococcus multilocularis somatostatin receptor 0.0047 0.0485 0.0482
Onchocerca volvulus Protein ultraspiracle homolog 0.0561 0.8148 1
Toxoplasma gondii proteasome subunit 0.01 0.1265 0.1517
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0265 0.3726 0.3725
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Entamoeba histolytica proteasome subunit beta type 1, putative 0.037 0.5304 0.6369
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0561 0.8148 0.8148
Echinococcus multilocularis proteasome subunit alpha type 6 0.01 0.1265 0.1263
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.01 0.1265 0.1263
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0007
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.001 0.0009
Onchocerca volvulus 0.0265 0.3726 0.4531
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0561 0.8148 0.8451
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0077 0.092 0.1094
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Brugia malayi CXXC zinc finger family protein 0.0028 0.02 0.0198
Brugia malayi Nuclear hormone receptor-like 1 0.0561 0.8148 0.8451
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Giardia lamblia 20S proteasome alpha subunit 4 0.01 0.1265 0.1519
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0561 0.8148 0.8208
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0485 0.0486
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0085 0.1048 0.1078
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.0485 0.0482
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0265 0.3726 0.3859
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.002 0.0021
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.0485 0.0482
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0077 0.092 0.1102
Echinococcus multilocularis serotonin receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0265 0.3726 0.3859
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0077 0.092 0.0952
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.227 0.2729
Leishmania major cytochrome p450-like protein 0.0077 0.092 0.0952
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.01 0.1265 0.1263
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0561 0.8148 0.8148
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.0485 0.0493
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0674 0.0671
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0561 0.8148 0.8451
Trypanosoma cruzi cytochrome P450, putative 0.0113 0.1464 0.1516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.01 0.1265 0.1263
Echinococcus granulosus proteasome prosome macropain 0.0573 0.8326 0.8386
Echinococcus granulosus sex peptide receptor 0.0047 0.0485 0.0486
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi proteasome subunit beta type 2 0.0233 0.3247 0.3362
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Brugia malayi Cytochrome P450 family protein 0.0113 0.1464 0.151
Onchocerca volvulus 0.0047 0.0485 0.0521
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0077 0.092 0.1102
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.001 0.0008
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0077 0.092 0.1102
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0077 0.092 0.1094
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0265 0.3726 0.4531
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Leishmania major proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.01 0.1265 1
Brugia malayi Nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Toxoplasma gondii cytochrome p450 superfamily protein 0.0077 0.092 0.1102
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0233 0.3247 0.3366
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.001 0.0009
Leishmania major hypothetical protein, conserved 0.0123 0.162 0.1678
Toxoplasma gondii proteasome subunit beta type 1, putative 0.037 0.5304 0.6369
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0233 0.3247 0.3366
Loa Loa (eye worm) proteasome subunit beta type 1 0.037 0.5304 0.5497
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit alpha type-7, putative 0.01 0.1265 0.1517
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.0485 0.0482
Brugia malayi conserved hypotetical protein 0.0265 0.3726 0.3859
Brugia malayi proteasome subunit alpha type 4 0.01 0.1265 0.1303
Echinococcus multilocularis phospholipase D1 0.0101 0.1291 0.1288
Brugia malayi Cytochrome P450 family protein 0.0077 0.092 0.0945
Schistosoma mansoni opsin-like receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi larval opioid receptor 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit beta type-6, putative 0.01 0.1265 0.1517
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.0485 0.0486
Brugia malayi nuclear hormone receptor family member nhr-6 0.0265 0.3726 0.3859
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0265 0.3726 0.3725
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.2404 0.1614
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0485 0.0482
Mycobacterium ulcerans proteasome PrcA 0.01 0.1265 0.1517
Echinococcus multilocularis microtubule associated protein 2 0.068 0.9927 0.9927
Entamoeba histolytica phospholipase D, putative 0.0101 0.1291 0.1548
Brugia malayi hypothetical protein 0.0016 0.002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Schistosoma mansoni hypothetical protein 0.0077 0.092 0.0918
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0077 0.092 0.1094
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0063 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0561 0.8148 0.8208
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0561 0.8148 0.8451
Echinococcus granulosus proteasome subunit beta t family 0.01 0.1265 0.1272
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0485 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0077 0.092 0.1094
Echinococcus granulosus somatostatin receptor 0.0047 0.0485 0.0486
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Brugia malayi hypothetical protein 0.0035 0.0307 0.0309
Echinococcus granulosus proteasome subunit alpha type 6 0.01 0.1265 0.1272
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0485 0.0486
Plasmodium vivax proteasome subunit alpha type-3, putative 0.01 0.1265 0.1517
Leishmania major proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0233 0.3247 0.3898
Echinococcus granulosus dnaJ subfamily B 0.0403 0.5794 0.5835
Echinococcus multilocularis proteasome subunit beta type 6 0.01 0.1265 0.1263
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0077 0.092 0.1094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0561 0.8148 0.8148
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0265 0.3726 0.3725
Leishmania major proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0561 0.8148 1
Trypanosoma brucei proteasome beta 6 subunit 0.037 0.5304 0.55
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0561 0.8148 0.8451
Leishmania major proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.01 0.1265 0.1517
Echinococcus multilocularis phospholipase d3 0.0019 0.0063 0.0061
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0265 0.3726 0.4531
Brugia malayi orphan nuclear receptor NR2E1 0.0265 0.3726 0.3859
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi photoreceptor-specific nuclear receptor 0.0561 0.8148 0.8451
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0077 0.092 0.1102
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0561 0.8148 0.8451
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0511 0.052
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0561 0.8148 0.8451
Echinococcus multilocularis GPCR, family 2 0.0016 0.001 0.0007
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.0485 0.0493
Brugia malayi nuclear hormone receptor 0.0561 0.8148 0.8451
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Echinococcus multilocularis orexin receptor type 2 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.01 0.1265 0.1303
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0233 0.3247 0.3245
Loa Loa (eye worm) hypothetical protein 0.0059 0.0665 0.068
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0077 0.092 0.1102
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.01 0.1265 0.1263
Schistosoma mansoni cpg binding protein 0.003 0.0224 0.0222
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) steroid hormone receptor 0.0561 0.8148 0.8451
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.0485 0.0493
Trypanosoma cruzi cytochrome P450, putative 0.0113 0.1464 0.1516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit alpha type, putative 0.01 0.1265 0.1517
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus FTZ F1 alpha 0.0561 0.8148 0.8208
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0123 0.162 0.1678
Trypanosoma brucei proteasome beta 7 subunit 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.002 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0485 0.0486
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.0485 0.0521
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.0485 0.0493
Onchocerca volvulus 0.0047 0.0485 0.0521
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0511 0.052
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0077 0.092 0.1094
Leishmania major proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0561 0.8148 0.8451
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0573 0.8326 1
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Echinococcus multilocularis ecdysone induced protein 78C 0.0561 0.8148 0.8148
Echinococcus multilocularis proteasome subunit alpha type 2 0.01 0.1265 0.1263
Trypanosoma cruzi cardiolipin synthetase, putative 0.0035 0.0305 0.0314
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0561 0.8148 0.8451
Brugia malayi Proteasome subunit alpha type 1 0.01 0.1265 0.1303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0561 0.8148 0.8451
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0661 0.9641 1
Brugia malayi cytochrome P450 0.0077 0.092 0.0945
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.001 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.0485 0.0493
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.01 0.1265 0.1517
Brugia malayi Cytochrome P450 family protein 0.0113 0.1464 0.151
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0077 0.092 0.1094
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0016 0.002 0.5
Giardia lamblia 20S proteasome alpha subunit 6 0.01 0.1265 0.1519
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.0485 0.0482
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0561 0.8148 0.8451
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.01 0.1265 0.1509
Loa Loa (eye worm) CYP4Cod1 0.0113 0.1464 0.151
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0561 0.8148 0.8451
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit alpha type-4, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Echinococcus multilocularis Proteasome subunit alpha type 7 0.01 0.1265 0.1263
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus ecdysone induced protein 78C 0.0561 0.8148 0.8208
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.0485 0.0482
Brugia malayi AKH receptor 0.0047 0.0485 0.0493
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.01 0.1265 0.1517
Echinococcus multilocularis 0.0077 0.092 0.0918
Echinococcus multilocularis nuclear receptor nhr 48 0.0265 0.3726 0.3725
Loa Loa (eye worm) proteasome subunit beta type 2 0.0233 0.3247 0.3362
Trypanosoma brucei C-8 sterol isomerase, putative 0.0661 0.9641 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0077 0.092 0.1094
Giardia lamblia 20S proteasome alpha subunit 1 0.01 0.1265 0.1519
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.0485 0.0486
Schistosoma mansoni nuclear receptor 0.0265 0.3726 0.3725
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0233 0.3247 0.2808
Schistosoma mansoni nuclear hormone receptor 0.0265 0.3726 0.3725
Echinococcus granulosus phospholipase d3 0.0019 0.0063 0.0061
Leishmania major proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.01 0.1265 0.1517
Brugia malayi GnHR receptor homolog 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Schistosoma mansoni nuclear hormone receptor 0.0265 0.3726 0.3725
Echinococcus multilocularis FTZ F1 alpha 0.0561 0.8148 0.8148
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0561 0.8148 0.8451
Echinococcus granulosus allatostatin A receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.5794 0.5792
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Trypanosoma brucei ATP-dependent protease subunit HslV 0.01 0.1265 0.131
Leishmania major proteasome beta 5 subunit, putative 0.0573 0.8326 0.8636
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.01 0.1265 0.1263
Brugia malayi proteasome subunit alpha type 2 0.01 0.1265 0.1303
Onchocerca volvulus 0.0047 0.0485 0.0521
Plasmodium vivax proteasome subunit alpha type-5, putative 0.01 0.1265 0.1517
Plasmodium vivax proteasome subunit alpha type-2, putative 0.01 0.1265 0.1517
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0561 0.8148 0.8208
Echinococcus multilocularis proteasome subunit beta type 7 0.01 0.1265 0.1263
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0573 0.8326 0.8634
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis phospholipase D 0.009 0.1114 0.1112
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0561 0.8148 0.8148
Echinococcus granulosus GPCR family 2 0.0016 0.001 0.0007
Loa Loa (eye worm) proteasome subunit alpha type 1 0.01 0.1265 0.1303
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.01 0.1265 0.1517
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0077 0.092 0.1102
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0276
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0362 0.5176 0.5175
Plasmodium falciparum proteasome subunit beta type-7, putative 0.01 0.1265 0.1517
Onchocerca volvulus 0.0047 0.0485 0.0521
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0077 0.092 0.1102
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0561 0.8148 0.8148
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.01 0.1265 0.1517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Brugia malayi G-protein coupled receptor 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0077 0.092 0.1094
Brugia malayi G protein-coupled receptor 0.0047 0.0485 0.0493
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Schistosoma mansoni histamine h1 receptor 0.0047 0.0485 0.0482
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0233 0.3247 0.3898
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni cpg binding protein 0.0028 0.02 0.0198
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.01 0.1265 0.1517
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Toxoplasma gondii proteasome subunit beta type, putative 0.0573 0.8326 1
Onchocerca volvulus 0.0063 0.0714 0.0805
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.002 0.0017
Brugia malayi proteasome subunit alpha type 3 0.01 0.1265 0.1303
Onchocerca volvulus 0.0047 0.0485 0.0521
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.01 0.1265 0.131
Brugia malayi ecdysteroid receptor 0.0561 0.8148 0.8451
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0035 0.0305 0.0364
Leishmania major proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.01 0.1265 0.1517
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0561 0.8148 0.8451
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0485 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0077 0.092 0.1094
Trypanosoma brucei proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni hypothetical protein 0.0047 0.0485 0.0482
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.01 0.1265 0.131
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0265 0.3726 0.3725
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Leishmania major proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0265 0.3726 0.3725
Schistosoma mansoni nuclear receptor nhr-48 0.0265 0.3726 0.3725
Leishmania major cytochrome p450-like protein 0.0113 0.1464 0.1516
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.0485 0.0482
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0561 0.8148 0.8148
Giardia lamblia Proteasome subunit beta type 9 precursor 0.01 0.1265 0.1519
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi RE15519p 0.0047 0.0485 0.0493
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.0485 0.0493
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Onchocerca volvulus 0.0123 0.162 0.1925
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.002 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Onchocerca volvulus 0.0047 0.0485 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.01 0.1265 0.1517
Schistosoma mansoni steroid hormone receptor ad4bp 0.0561 0.8148 0.8148
Schistosoma mansoni thyroid hormone receptor 0.0685 1 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0077 0.092 0.1102
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.01 0.1265 0.0466
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.01 0.1265 0.1263
Brugia malayi Melatonin receptor type 1A 0.0047 0.0485 0.0493
Plasmodium falciparum proteasome subunit beta type-1, putative 0.037 0.5304 0.6369
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.1629 0.1627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Echinococcus granulosus nuclear receptor nhr 48 0.0265 0.3726 0.3752
Toxoplasma gondii proteasome subunit alpha1, putative 0.01 0.1265 0.1517
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0561 0.8148 0.8208
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Brugia malayi sulfakinin receptor protein 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.0485 0.0482
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.01 0.1265 0.131
Giardia lamblia Proteasome subunit beta type 3 0.01 0.1265 0.1519
Brugia malayi nuclear hormone receptor 0.0265 0.3726 0.3859
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0077 0.092 0.1102
Schistosoma mansoni nuclear hormone receptor 0.0561 0.8148 0.8148
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.0485 0.0486
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.3576 0.3703
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0578 0.0691
Trypanosoma brucei Emopamil binding protein, putative 0.0123 0.162 0.1678
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.0485 0.0482
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Leishmania major proteasome beta 2 subunit, putative 0.0233 0.3247 0.3366
Loa Loa (eye worm) hypothetical protein 0.0085 0.1048 0.1078
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.0485 0.0482
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Echinococcus granulosus serotonin receptor 0.0047 0.0485 0.0486
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus g-protein coupled receptor 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0561 0.8148 0.8148
Schistosoma mansoni microtubule-associated protein tau 0.068 0.9927 0.9927
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.01 0.1265 0.1303
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.0485 0.0482
Brugia malayi neuropeptide F receptor 0.0047 0.0485 0.0493
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.01 0.1265 0.1517
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0077 0.092 0.1102
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0485 0.0482
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.002 0.0021
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Schistosoma mansoni hypothetical protein 0.0167 0.227 0.2268
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.01 0.1265 0.1263
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.0485 0.0482
Giardia lamblia Proteasome subunit beta type 4 precursor 0.01 0.1265 0.1519
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Trypanosoma brucei proteasome beta 3 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Giardia lamblia 20S proteasome alpha subunit 5 0.01 0.1265 0.1519
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.002 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.3576 0.3273
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit beta type-3, putative 0.01 0.1265 0.1517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit beta type-6, putative 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.01 0.1265 0.1517
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi putative neuropeptide receptor 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit alpha type-1, putative 0.01 0.1265 0.1517
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0077 0.092 0.1094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0561 0.8148 0.8451
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Brugia malayi hypothetical protein 0.0265 0.3726 0.3859
Onchocerca volvulus 0.0028 0.02 0.0169
Brugia malayi Proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Loa Loa (eye worm) hypothetical protein 0.0036 0.0322 0.0324
Trypanosoma brucei proteasome alpha 7 subunit 0.01 0.1265 0.131
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0233 0.3247 0.3245
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni hypothetical protein 0.0403 0.5794 0.5792
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus granulosus neuropeptide receptor 0.0047 0.0485 0.0486
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.037 0.5304 0.572
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni nuclear receptor 0.0265 0.3726 0.3725
Echinococcus multilocularis Proteasome, subunit alpha beta 0.01 0.1265 0.1263
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus multilocularis subfamily T1A non peptidase ue 0.01 0.1265 0.1263
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.0485 0.0486
Brugia malayi Phospholipase d protein 1 0.0101 0.1291 0.133
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0265 0.3726 0.3752
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0047 0.0485 0.0493
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.037 0.5304 0.55
Brugia malayi hypothetical protein 0.0296 0.42 0.4351
Echinococcus multilocularis neuropeptide s receptor 0.0501 0.7251 0.725
Brugia malayi Proteasome A-type and B-type family protein 0.0573 0.8326 0.8634
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.0485 0.0482
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0077 0.092 0.1094
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0077 0.092 0.1094
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0063 0.0063
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0085 0.1048 0.1257
Loa Loa (eye worm) nuclear hormone receptor 0.0265 0.3726 0.3859
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.01 0.1265 0.1263
Brugia malayi G-protein coupled receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Plasmodium vivax proteasome subunit beta type-5, putative 0.0573 0.8326 1
Entamoeba histolytica hypothetical protein 0.0035 0.0307 0.0366
Brugia malayi follicle stimulating hormone receptor 0.0047 0.0485 0.0493
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Brugia malayi proteasome subunit alpha type 6 0.01 0.1265 0.1303
Schistosoma mansoni hypothetical protein 0.0167 0.227 0.2268
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.0485 0.0482
Brugia malayi nuclear receptor RXR 0.0296 0.42 0.4351
Loa Loa (eye worm) hypothetical protein 0.0049 0.0511 0.052
Brugia malayi Nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit beta type-5 0.0573 0.8326 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0296 0.42 0.4198
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0561 0.8148 0.8208
Echinococcus granulosus Nuclear hormone receptor HR96 0.0265 0.3726 0.3752
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0233 0.3247 0.3269
Brugia malayi nuclear hormone receptor family member odr-7 0.0265 0.3726 0.3859
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.01 0.1265 0.1263
Brugia malayi Serotonin receptor 0.0047 0.0485 0.0493
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0077 0.092 0.1102
Echinococcus granulosus cytochrome P450 2K1 0.0077 0.092 0.0924
Echinococcus multilocularis proteasome (prosome, macropain) 0.0573 0.8326 0.8325
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0007
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0077 0.092 0.1102
Echinococcus multilocularis geminin 0.0167 0.227 0.2268
Brugia malayi hypothetical protein 0.0296 0.42 0.4351
Echinococcus granulosus proteasome subunit beta type 7 0.01 0.1265 0.1272
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0482
Echinococcus granulosus Proteasome subunit alpha type 7 0.01 0.1265 0.1272
Brugia malayi proteasome subunit beta type 1 0.037 0.5304 0.5497
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.01 0.1265 0.1263
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.01 0.1265 0.1517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni hypothetical protein 0.0035 0.0307 0.0304
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0485 0.0482
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0296 0.42 0.4198
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0573 0.8326 0.8636
Chlamydia trachomatis phospholipase D superfamily protein 0.0016 0.002 0.5
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0296 0.42 0.4351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni zinc finger protein 0.0265 0.3726 0.3725
Plasmodium falciparum proteasome subunit beta type-3, putative 0.01 0.1265 0.1517
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.01 0.1265 0.131
Brugia malayi proteasome subunit beta type 3 0.01 0.1265 0.1303
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0113 0.1464 0.1756
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0233 0.3247 0.3898
Giardia lamblia Proteasome subunit beta type 2 0.0233 0.3247 0.39
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0561 0.8148 0.8451
Echinococcus multilocularis allatostatin A receptor 0.0047 0.0485 0.0482
Onchocerca volvulus 0.0047 0.0485 0.0521
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0561 0.8148 0.8451
Echinococcus granulosus subfamily T1A non peptidase ue 0.01 0.1265 0.1272
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.2404 0.1614
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.01 0.1265 0.1517
Plasmodium vivax proteasome subunit beta type-4, putative 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.01 0.1265 0.1517
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0485 0.0482
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0077 0.092 0.1094
Onchocerca volvulus 0.0047 0.0485 0.0521
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0307 0.0304
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Echinococcus granulosus hypothetical protein 0.0047 0.0485 0.0486
Echinococcus granulosus g protein coupled receptor 0.0047 0.0485 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.227 0.1424
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.0485 0.0482
Brugia malayi hypothetical protein 0.0047 0.0485 0.0493
Brugia malayi Cytochrome P450 family protein 0.0077 0.092 0.0945
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.01 0.1265 0.1263
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0077 0.092 0.1102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0561 0.8148 0.8451
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0561 0.8148 0.8148
Entamoeba histolytica proteasome subunit beta type 3, putative 0.01 0.1265 0.1517
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.0485 0.0482
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.01 0.1265 0.1517
Trypanosoma brucei proteasome beta-1 subunit, putative 0.01 0.1265 0.131
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.0485 0.0482
Schistosoma mansoni adenoreceptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0144 0.1924 0.1987
Plasmodium falciparum proteasome subunit beta type-4 0.01 0.1265 0.1517
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.01 0.1265 0.1517
Loa Loa (eye worm) hypothetical protein 0.0034 0.0279 0.028
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0661 0.9641 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) PAS-3 protein 0.01 0.1265 0.1303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni biogenic amine receptor 0.0047 0.0485 0.0482
Mycobacterium ulcerans proteasome PrcB 0.0573 0.8326 1
Echinococcus granulosus microtubule associated protein 2 0.068 0.9927 1
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.0485 0.0482
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0485 0.0482
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.01 0.1265 0.1517
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.01 0.1265 0.131
Echinococcus multilocularis serotonin receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Giardia lamblia Proteasome subunit beta type 1 0.037 0.5304 0.637
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Echinococcus granulosus orexin receptor type 2 0.0047 0.0485 0.0486
Giardia lamblia Proteasome subunit beta type 7 precursor 0.01 0.1265 0.1519
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0077 0.092 0.1102
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0485 0.0493
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.01 0.1265 0.131
Loa Loa (eye worm) DR-78 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.01 0.1265 0.1303
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.01 0.1265 0.1272
Schistosoma mansoni phospholipase D 0.0101 0.1291 0.1288
Schistosoma mansoni RAR-like nuclear receptor 0.0561 0.8148 0.8148
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0077 0.092 0.0952
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0077 0.092 0.1094
Loa Loa (eye worm) hypothetical protein 0.0066 0.0763 0.0782
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.001 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0485 0.0482
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Echinococcus granulosus phospholipase D1 0.0101 0.1291 0.1298
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.0485 0.0493
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.01 0.1265 0.131
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.01 0.1265 0.1517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0573 0.8326 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0265 0.3726 0.3752
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0485 0.0482
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.0485 0.0493
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.01 0.1265 0.1263
Trypanosoma brucei cytochrome P450, putative 0.0113 0.1464 0.1516
Brugia malayi Proteasome subunit alpha type 7-1 0.01 0.1265 0.1303
Loa Loa (eye worm) proteasome subunit alpha type 2 0.01 0.1265 0.1303
Brugia malayi ecdysone receptor 0.0265 0.3726 0.3859
Echinococcus granulosus geminin 0.0167 0.227 0.2285
Trypanosoma brucei cardiolipin synthetase 0.0035 0.0305 0.0314
Loa Loa (eye worm) hypothetical protein 0.0561 0.8148 0.8451
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0485 0.0482
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0077 0.092 0.0952
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0561 0.8148 0.8148
Echinococcus granulosus proteasome prosome macropain subunit beta 0.037 0.5304 0.5341
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0296 0.42 0.4351
Echinococcus multilocularis neuropeptide receptor A26 0.0501 0.7251 0.725
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0561 0.8148 0.8451
Trypanosoma cruzi 20S proteasome subunit 0.0233 0.3247 0.3366
Onchocerca volvulus 0.0047 0.0485 0.0521
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Brugia malayi Steroid receptor seven-up type 2 0.0561 0.8148 0.8451
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.001 0.0008
Loa Loa (eye worm) cytochrome P450 0.0077 0.092 0.0945
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.01 0.1265 0.1517
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.01 0.1265 0.1517
Echinococcus granulosus neuropeptide receptor 0.0047 0.0485 0.0486
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.037 0.5304 0.5302
Loa Loa (eye worm) cytochrome P450 family protein 0.0077 0.092 0.0945
Toxoplasma gondii heat shock protein hslv, putative 0.01 0.1265 0.1517
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0485 0.0482
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0077 0.092 0.1102
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0077 0.092 0.1094
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Toxoplasma gondii peptidase, T1 family protein 0.01 0.1265 0.1517
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0485 0.0482
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0485 0.0482
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Leishmania major proteasome beta 7 subunit, putative 0.01 0.1265 0.131
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0561 0.8148 0.8208
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.0485 0.0486
Brugia malayi Dopamine receptor protein 2 0.0047 0.0485 0.0493
Schistosoma mansoni amine GPCR 0.0047 0.0485 0.0482
Schistosoma mansoni neuropeptide receptor 0.0047 0.0485 0.0482
Giardia lamblia 20S proteasome alpha subunit 3 0.01 0.1265 0.1519
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0265 0.3726 0.3859
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.02 0.0198
Schistosoma mansoni coup transcription factor 0.0561 0.8148 0.8148
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0077 0.092 0.1102
Brugia malayi nuclear receptor NHR-88 0.0265 0.3726 0.3859
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma brucei cardiolipin synthetase, putative 0.0035 0.0305 0.0314
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0485 0.0486
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.01 0.1265 0.131
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0307 0.0304
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.1464 0.151
Echinococcus granulosus cpg binding protein 0.003 0.0224 0.0223
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0233 0.3247 0.3245
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.0485 0.0493
Echinococcus granulosus thyroid hormone receptor alpha 0.0265 0.3726 0.3752
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.01 0.1265 0.131
Leishmania major cardiolipin synthetase, putative 0.0016 0.002 0.0018
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.0485 0.0486
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.0485 0.0482
Loa Loa (eye worm) hypothetical protein 0.0338 0.4819 0.4993
Toxoplasma gondii proteasome beta subunit 0.01 0.1265 0.1517
Onchocerca volvulus 0.0047 0.0485 0.0521
Echinococcus granulosus neuropeptide s receptor 0.0501 0.7251 0.7303
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.01 0.1265 0.1517
Onchocerca volvulus 0.0047 0.0485 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0485 0.0486
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0265 0.3726 0.3725
Brugia malayi nuclear receptor NHR-67 0.0265 0.3726 0.3859
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0077 0.092 0.1102
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0485 0.0486
Brugia malayi neuropeptide F receptor 0.0047 0.0485 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0077 0.092 0.1094
Loa Loa (eye worm) phospholipase D 0.0019 0.0063 0.0055
Brugia malayi Protein K4 0.0016 0.002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0485 0.0493
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.01 0.1265 0.131
Brugia malayi 20S proteasome alpha5 subunit 0.01 0.1265 0.1303
Brugia malayi Nuclear hormone receptor E75 0.0265 0.3726 0.3859
Loa Loa (eye worm) proteasome subunit beta type 3 0.01 0.1265 0.1303
Onchocerca volvulus 0.0047 0.0485 0.0521
Trypanosoma cruzi cardiolipin synthetase, putative 0.0035 0.0305 0.0314

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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