Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0412 | 0.3364 | 0.335 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.079 | 0.654 | 0.9887 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0412 | 0.3364 | 0.5085 |
Entamoeba histolytica | protein kinase, putative | 0.0412 | 0.3364 | 0.3364 |
Echinococcus multilocularis | protein kinase c iota type | 0.0412 | 0.3364 | 0.5085 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.1203 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0412 | 0.3364 | 0.0111 |
Toxoplasma gondii | AGC kinase | 0.1203 | 1 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0412 | 0.3364 | 0.335 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0412 | 0.3364 | 0.5085 |
Brugia malayi | Protein kinase domain containing protein | 0.1203 | 1 | 1 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0799 | 0.6615 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.079 | 0.654 | 0.9887 |
Echinococcus granulosus | protein kinase c iota type | 0.0412 | 0.3364 | 0.5085 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0412 | 0.3364 | 0.5085 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0412 | 0.3364 | 0.5085 |
Entamoeba histolytica | protein kinase 2, putative | 0.0799 | 0.6615 | 0.6615 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0014 | 0.002 | 0.0031 |
Trichomonas vaginalis | AGC family protein kinase | 0.0412 | 0.3364 | 0.0111 |
Entamoeba histolytica | protein kinase, putative | 0.1203 | 1 | 1 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0799 | 0.6615 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0014 | 0.002 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.1203 | 1 | 1 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0412 | 0.3364 | 0.5085 |
Entamoeba histolytica | protein kinase, putative | 0.1203 | 1 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0412 | 0.3364 | 0.335 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0799 | 0.6615 | 1 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0412 | 0.3364 | 0.5085 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0412 | 0.3364 | 0.5085 |
Giardia lamblia | Kinase, AGC PKA | 0.0799 | 0.6615 | 0.5 |
Echinococcus multilocularis | nervana 2 | 0.079 | 0.654 | 0.9887 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0014 | 0.002 | 0.0031 |
Brugia malayi | protein kinase C II. | 0.0412 | 0.3364 | 0.335 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0412 | 0.3364 | 0.335 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0799 | 0.6615 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0799 | 0.6615 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0412 | 0.3364 | 0.335 |
Trichomonas vaginalis | AGC family protein kinase | 0.0412 | 0.3364 | 0.0111 |
Brugia malayi | Protein kinase domain containing protein | 0.0412 | 0.3364 | 0.335 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0799 | 0.6615 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0412 | 0.3364 | 0.5085 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0412 | 0.3364 | 0.335 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0412 | 0.3364 | 0.5085 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0014 | 0.002 | 0.5 |
Echinococcus multilocularis | nervana 2 | 0.079 | 0.654 | 0.9887 |
Entamoeba histolytica | protein kinase, putative | 0.1203 | 1 | 1 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0799 | 0.6615 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.1203 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0412 | 0.3364 | 0.335 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0412 | 0.3364 | 0.5085 |
Echinococcus granulosus | nervana 2 | 0.079 | 0.654 | 0.9887 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0799 | 0.6615 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0014 | 0.002 | 0.002 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0412 | 0.3364 | 0.5085 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0412 | 0.3364 | 0.5085 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0412 | 0.3364 | 0.5085 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0412 | 0.3364 | 0.5085 |
Echinococcus granulosus | nervana 2 | 0.079 | 0.654 | 0.9887 |
Trichomonas vaginalis | AGC family protein kinase | 0.1203 | 1 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0412 | 0.3364 | 0.5085 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.079 | 0.654 | 0.9887 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0799 | 0.6615 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0412 | 0.3364 | 0.335 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.079 | 0.654 | 0.9887 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0799 | 0.6615 | 0.6615 |
Trypanosoma cruzi | Protein kinase B | 0.0799 | 0.6615 | 1 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0412 | 0.3364 | 0.5085 |
Trichomonas vaginalis | AGC family protein kinase | 0.0412 | 0.3364 | 0.0111 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0799 | 0.6615 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0412 | 0.3364 | 0.335 |
Echinococcus granulosus | NDR protein kinase | 0.0412 | 0.3364 | 0.5085 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0799 | 0.6615 | 0.6615 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0799 | 0.6615 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.