Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0384 | 0.3362 | 0.0111 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0384 | 0.3362 | 0.3353 |
Entamoeba histolytica | protein kinase, putative | 0.1121 | 1 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0745 | 0.6614 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0737 | 0.6539 | 0.9887 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0737 | 0.6539 | 0.9887 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0384 | 0.3362 | 0.5083 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0384 | 0.3362 | 0.5083 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0013 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0737 | 0.6539 | 0.9887 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0384 | 0.3362 | 0.3353 |
Trypanosoma cruzi | Protein kinase B | 0.0745 | 0.6614 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0384 | 0.3362 | 0.5083 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0384 | 0.3362 | 0.5083 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0013 | 0.0019 |
Trichomonas vaginalis | AGC family protein kinase | 0.0384 | 0.3362 | 0.0111 |
Brugia malayi | Hr1 repeat family protein | 0.0384 | 0.3362 | 0.3353 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0013 | 0.0019 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0384 | 0.3362 | 0.5083 |
Entamoeba histolytica | protein kinase, putative | 0.1121 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0384 | 0.3362 | 0.3353 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0745 | 0.6614 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0384 | 0.3362 | 0.5083 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0737 | 0.6539 | 0.9887 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0384 | 0.3362 | 0.5083 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0745 | 0.6614 | 0.6614 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0745 | 0.6614 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.1121 | 1 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0384 | 0.3362 | 0.3353 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0384 | 0.3362 | 0.5083 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0384 | 0.3362 | 0.3353 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0384 | 0.3362 | 0.5083 |
Trichomonas vaginalis | AGC family protein kinase | 0.0384 | 0.3362 | 0.0111 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0384 | 0.3362 | 0.5083 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0745 | 0.6614 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.1121 | 1 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0745 | 0.6614 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.0745 | 0.6614 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0384 | 0.3362 | 0.5083 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0384 | 0.3362 | 0.5083 |
Entamoeba histolytica | protein kinase 2, putative | 0.0745 | 0.6614 | 0.6614 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0384 | 0.3362 | 0.5083 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 0.3362 | 0.3353 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0384 | 0.3362 | 0.5083 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0745 | 0.6614 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0013 | 0.0013 |
Entamoeba histolytica | protein kinase, putative | 0.0384 | 0.3362 | 0.3362 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0384 | 0.3362 | 0.5083 |
Trichomonas vaginalis | AGC family protein kinase | 0.0384 | 0.3362 | 0.0111 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0384 | 0.3362 | 0.5083 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0745 | 0.6614 | 1 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0745 | 0.6614 | 0.5 |
Brugia malayi | protein kinase C II. | 0.0384 | 0.3362 | 0.3353 |
Trichomonas vaginalis | AGC family protein kinase | 0.1121 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0745 | 0.6614 | 0.6614 |
Echinococcus multilocularis | protein kinase c iota type | 0.0384 | 0.3362 | 0.5083 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 0.3362 | 0.3353 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0745 | 0.6614 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0384 | 0.3362 | 0.5083 |
Echinococcus granulosus | nervana 2 | 0.0737 | 0.6539 | 0.9887 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.1121 | 1 | 1 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0745 | 0.6614 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0384 | 0.3362 | 0.3353 |
Echinococcus granulosus | protein kinase c iota type | 0.0384 | 0.3362 | 0.5083 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0737 | 0.6539 | 0.9887 |
Toxoplasma gondii | AGC kinase | 0.1121 | 1 | 0.5 |
Echinococcus granulosus | nervana 2 | 0.0737 | 0.6539 | 0.9887 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0745 | 0.6614 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0012 | 0.0013 | 0.5 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.1121 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.1121 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0737 | 0.6539 | 0.9887 |
Loa Loa (eye worm) | hypothetical protein | 0.0384 | 0.3362 | 0.3353 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.