Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase domain containing protein | 0.0396 | 0.332 | 0.3276 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0396 | 0.332 | 0.332 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0767 | 0.6593 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0396 | 0.332 | 0.332 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.1154 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0767 | 0.6593 | 0.4899 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0759 | 0.6518 | 0.977 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0759 | 0.6518 | 0.977 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0.0066 | 0.5 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0767 | 0.6593 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0396 | 0.332 | 0.332 |
Entamoeba histolytica | protein kinase, putative | 0.1154 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.1154 | 1 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0026 | 0.0066 | 0.0066 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0759 | 0.6518 | 0.977 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0396 | 0.332 | 0.332 |
Echinococcus granulosus | nervana 2 | 0.0759 | 0.6518 | 0.977 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Entamoeba histolytica | protein kinase 2, putative | 0.0767 | 0.6593 | 0.4899 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0759 | 0.6518 | 0.977 |
Echinococcus granulosus | nervana 2 | 0.0759 | 0.6518 | 0.977 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0767 | 0.6593 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0767 | 0.6593 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.0767 | 0.6593 | 0.5 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0767 | 0.6593 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0066 | 0.0066 |
Brugia malayi | Protein kinase domain containing protein | 0.0396 | 0.332 | 0.3276 |
Trichomonas vaginalis | AGC family protein kinase | 0.0396 | 0.332 | 0.0111 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0767 | 0.6593 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0396 | 0.332 | 0.3276 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0767 | 0.6593 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.1154 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0396 | 0.332 | 0.0111 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0767 | 0.6593 | 0.4899 |
Echinococcus multilocularis | nervana 2 | 0.0759 | 0.6518 | 0.977 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0767 | 0.6593 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0.0066 | 0.5 |
Trypanosoma cruzi | Protein kinase B | 0.0767 | 0.6593 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0396 | 0.332 | 0.332 |
Toxoplasma gondii | AGC kinase | 0.1154 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0767 | 0.6593 | 1 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0767 | 0.6593 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0396 | 0.332 | 0.332 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0767 | 0.6593 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.1154 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0066 | 0.0066 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.1154 | 1 | 1 |
Brugia malayi | protein kinase C II. | 0.0396 | 0.332 | 0.3276 |
Entamoeba histolytica | protein kinase, putative | 0.1154 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1154 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0396 | 0.332 | 0.0111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0396 | 0.332 | 0.0111 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0759 | 0.6518 | 0.977 |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 0.332 | 0.332 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.