Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0696 | 1 | 1 |
Echinococcus granulosus | nervana 2 | 0.0457 | 0.6441 | 0.977 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0238 | 0.3173 | 0.3173 |
Toxoplasma gondii | AGC kinase | 0.0696 | 1 | 0.5 |
Giardia lamblia | Kinase, AGC PKA | 0.0462 | 0.6517 | 0.5 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0457 | 0.6441 | 0.977 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0457 | 0.6441 | 0.977 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0462 | 0.6517 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0462 | 0.6517 | 1 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0462 | 0.6517 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0462 | 0.6517 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0238 | 0.3173 | 0.3173 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0462 | 0.6517 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0238 | 0.3173 | 0.0111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0238 | 0.3173 | 0.0111 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0462 | 0.6517 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.3173 | 0.3173 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0238 | 0.3173 | 0.3173 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0696 | 1 | 1 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0457 | 0.6441 | 0.977 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0462 | 0.6517 | 0.4899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0457 | 0.6441 | 0.977 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0462 | 0.6517 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0238 | 0.3173 | 0.0111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0457 | 0.6441 | 0.977 |
Trypanosoma cruzi | Protein kinase B | 0.0462 | 0.6517 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0238 | 0.3173 | 0.3173 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0 | 0.5 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0462 | 0.6517 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0696 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0462 | 0.6517 | 0.4899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0462 | 0.6517 | 0.5 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0238 | 0.3173 | 0.3173 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0462 | 0.6517 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0696 | 1 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0696 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0238 | 0.3173 | 0.3173 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0238 | 0.3173 | 0.3173 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0696 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0238 | 0.3173 | 0.3173 |
Echinococcus multilocularis | nervana 2 | 0.0457 | 0.6441 | 0.977 |
Trichomonas vaginalis | AGC family protein kinase | 0.0238 | 0.3173 | 0.0111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0696 | 1 | 1 |
Brugia malayi | protein kinase C II. | 0.0238 | 0.3173 | 0.3173 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0462 | 0.6517 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0696 | 1 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0238 | 0.3173 | 0.3173 |
Entamoeba histolytica | protein kinase 2, putative | 0.0462 | 0.6517 | 0.4899 |
Echinococcus granulosus | nervana 2 | 0.0457 | 0.6441 | 0.977 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.