Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0033 | 0.0071 | 0.0071 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0061 | 0.0421 | 0.0421 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0033 | 0.0071 | 0.0166 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0187 | 0.0434 |
Schistosoma mansoni | serine/threonine protein kinase | 0.021 | 0.231 | 0.5362 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0033 | 0.0071 | 0.0071 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0047 | 0.0245 | 0.0569 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0031 | 0.0046 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0149 | 0.1539 | 0.3573 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0042 | 0.0187 | 0.0434 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0187 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Echinococcus multilocularis | protein kinase c iota type | 0.0056 | 0.0361 | 0.0838 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0187 | 0.0187 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0033 | 0.0071 | 0.0026 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.008 | 0.0666 | 0.0666 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0061 | 0.0421 | 0.0977 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Brugia malayi | Protein kinase c protein 2 | 0.0178 | 0.1909 | 0.1872 |
Schistosoma mansoni | serine/threonine kinase | 0.0033 | 0.0071 | 0.0166 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0187 | 0.0187 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0071 | 0.0071 |
Echinococcus granulosus | protein kinase C gamma type | 0.0187 | 0.202 | 0.469 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.021 | 0.231 | 0.5362 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.1061 |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0187 | 0.0142 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.04 | 0.4731 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.021 | 0.231 | 0.5362 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0187 | 0.0142 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0187 | 0.0142 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0367 | 0.4308 | 1 |
Brugia malayi | protein kinase C II. | 0.0061 | 0.0421 | 0.0377 |
Loa Loa (eye worm) | thyroid receptor interactor | 0.0047 | 0.0245 | 0.0245 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0187 | 0.0187 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0061 | 0.0421 | 0.0977 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0033 | 0.0071 | 0.0166 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0187 | 0.0142 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0046 | 0.0046 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0031 | 0.0046 | 0.0106 |
Entamoeba histolytica | protein kinase, putative | 0.0033 | 0.0071 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.008 | 0.0666 | 0.1546 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.5 |
Onchocerca volvulus | 0.0042 | 0.0187 | 0.0395 | |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0033 | 0.0071 | 0.0166 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1539 | 0.1539 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0033 | 0.0071 | 0.0071 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0061 | 0.0421 | 0.0977 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0033 | 0.0071 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0149 | 0.1539 | 0.3573 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0033 | 0.0071 | 0.0166 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0187 | 0.0434 |
Brugia malayi | Protein kinase domain containing protein | 0.0033 | 0.0071 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0187 | 0.0395 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0033 | 0.0071 | 0.0071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0187 | 0.0142 |
Schistosoma mansoni | serine/threonine protein kinase | 0.021 | 0.231 | 0.5362 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0042 | 0.0187 | 0.0434 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0434 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0187 | 0.0142 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0149 | 0.1539 | 0.3573 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0033 | 0.0071 | 0.0166 |
Brugia malayi | Protein kinase domain containing protein | 0.0033 | 0.0071 | 0.0026 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0367 | 0.4308 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0367 | 0.4308 | 0.4308 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0367 | 0.4308 | 1 |
Brugia malayi | ecdysteroid receptor | 0.04 | 0.4731 | 0.4706 |
Brugia malayi | Fes/CIP4 homology domain containing protein | 0.0047 | 0.0245 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0046 | 0.0046 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0457 | 0.1061 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0457 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0033 | 0.0071 | 0.0026 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0031 | 0.0046 | 0.0106 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.008 | 0.0666 | 0.1546 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0047 | 0.0245 | 0.0569 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0457 | 0.1061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0187 | 0.0187 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0187 | 0.0434 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0187 | 0.0142 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.008 | 0.0666 | 0.1546 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0187 | 0.202 | 0.469 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0187 | 0.0142 |
Entamoeba histolytica | protein kinase, putative | 0.0033 | 0.0071 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0187 | 0.0142 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0033 | 0.0071 | 0.0071 |
Entamoeba histolytica | protein kinase, putative | 0.0033 | 0.0071 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0187 | 0.0142 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0033 | 0.0071 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0187 | 0.0142 |
Echinococcus granulosus | NDR protein kinase | 0.0033 | 0.0071 | 0.0166 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0187 | 0.0434 |
Brugia malayi | Hr1 repeat family protein | 0.008 | 0.0666 | 0.0623 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0187 | 0.0434 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.0384 | 0.0891 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.0384 | 0.0891 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0187 | 0.0142 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0187 | 0.0142 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0042 | 0.0187 | 0.0142 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0033 | 0.0071 | 0.0166 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.0384 | 0.0891 |
Loa Loa (eye worm) | hypothetical protein | 0.04 | 0.4731 | 0.4731 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0187 | 0.0434 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0033 | 0.0071 | 0.0166 |
Echinococcus granulosus | FTZ F1 alpha | 0.0042 | 0.0187 | 0.0434 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0187 | 0.0434 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0187 | 0.0434 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0042 | 0.0187 | 0.0142 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0187 | 0.0142 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0187 | 0.0395 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0187 | 0.0434 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0155 | 0.162 | 0.162 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.1829 | 0.1829 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | camk/mapkapk/mnk protein kinase | 0.0816 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0033 | 0.0071 | 0.0166 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0434 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0457 | 0.5 |
Schistosoma mansoni | atypical protein kinase C | 0.0056 | 0.0361 | 0.0838 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0033 | 0.0071 | 0.0166 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0187 | 0.0142 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0187 | 0.0434 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0187 | 0.0434 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0031 | 0.0046 | 0.0046 |
Entamoeba histolytica | protein kinase, putative | 0.0033 | 0.0071 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0187 | 0.0434 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0187 | 0.0434 |
Trichomonas vaginalis | AGC family protein kinase | 0.0033 | 0.0071 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0187 | 0.0142 |
Echinococcus granulosus | protein kinase c iota type | 0.0056 | 0.0361 | 0.0838 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0033 | 0.0071 | 0.0071 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0457 | 0.1061 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0367 | 0.4308 | 0.4282 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0046 | 0.0106 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0187 | 0.0434 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0033 | 0.0071 | 0.0166 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0046 | 0.0046 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.