Detailed information for compound 827157

Basic information

Technical information
  • TDR Targets ID: 827157
  • Name: 3-(2,2-dimethylpropanoylamino)-N-(2-fluorophe nyl)-1-benzofuran-2-carboxamide
  • MW: 354.375 | Formula: C20H19FN2O3
  • H donors: 2 H acceptors: 2 LogP: 4.72 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccccc1NC(=O)c1oc2c(c1NC(=O)C(C)(C)C)cccc2
  • InChi: 1S/C20H19FN2O3/c1-20(2,3)19(25)23-16-12-8-4-7-11-15(12)26-17(16)18(24)22-14-10-6-5-9-13(14)21/h4-11H,1-3H3,(H,22,24)(H,23,25)
  • InChiKey: KMKLGCUFWZWRFN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(2,2-dimethylpropanoylamino)-N-(2-fluorophenyl)benzofuran-2-carboxamide
  • 3-[(2,2-dimethyl-1-oxopropyl)amino]-N-(2-fluorophenyl)-2-benzofurancarboxamide
  • N-(2-fluorophenyl)-3-(pivaloylamino)benzofuran-2-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Trypanosoma cruzi subtilisin peptidase 0.0456 0.0407 0.5996
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0053 0.0017 0.0168
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0006 0.0005
Echinococcus granulosus short transient receptor potential channel 6 0.0041 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0047 0.0011 0.0013
Schistosoma mansoni transient receptor potential channel 0.0041 0.0006 0.0005
Schistosoma mansoni tyrosine kinase 0.0652 0.0597 0.0596
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0062 0.0026 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0086 0.0085
Loa Loa (eye worm) AGC/NDR protein kinase 0.0039 0.0004 0.0004
Echinococcus multilocularis conserved hypothetical protein 0.0041 0.0006 0.0006
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0006 0.0005
Plasmodium vivax NAD-dependent deacetylase, putative 0.0108 0.007 0.1681
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0189 0.0188
Loa Loa (eye worm) AGC/PKN protein kinase 0.0039 0.0004 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.007 0.0989
Toxoplasma gondii subtilisin SUB8 0.0456 0.0407 1
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0002 0.0001
Brugia malayi hypothetical protein 0.0038 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0053 0.0017 0.0197
Echinococcus granulosus nervana 2 0.0056 0.002 0.0019
Leishmania major arginine N-methyltransferase-like protein 0.0094 0.0057 0.0765
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0142 0.0103 0.2498
Schistosoma mansoni protein kinase 0.0127 0.0089 0.0088
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0053 0.0017 0.0168
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0006 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0041 0.0006 0.0089
Brugia malayi Protein kinase domain containing protein 0.0044 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0201 0.016 0.016
Loa Loa (eye worm) voltage-gated potassium channel 0.0041 0.0006 0.0006
Brugia malayi hypothetical protein 0.0477 0.0428 0.0428
Plasmodium vivax subtilisin-like protease 1 0.0456 0.0407 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0126 0.0088 0.0087
Echinococcus granulosus methyltransferase protein 5 0.0053 0.0017 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus sodium channel protein 0.0041 0.0006 0.0005
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0045 0.0788
Onchocerca volvulus 0.0038 0.0002 0.0029
Brugia malayi hypothetical protein 0.0147 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0008 0.001
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.2062 0.1963 0.3216
Schistosoma mansoni btb and poz domain-containing protein 0.0044 0.0008 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0147 0.0108 0.1534
Echinococcus multilocularis glutamate receptor 2 0.0047 0.0011 0.0013
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0456 0.0407 1
Echinococcus granulosus integrin alpha ps 0.0248 0.0206 0.0205
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0045 0.0924
Onchocerca volvulus 0.0456 0.0407 0.5808
Loa Loa (eye worm) acyl carrier protein 0.0037 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0039 0.0004 0.0004
Toxoplasma gondii SWIRM domain-containing protein 0.0059 0.0023 0.0512
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0053 0.0017 0.002
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2684 0.2566 0.2565
Giardia lamblia High cysteine protein 0.0089 0.0052 0.0085
Brugia malayi EGF-like domain containing protein 0.0089 0.0052 0.0052
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.004 0.0666
Plasmodium vivax plasmepsin V, putative 0.0425 0.0377 0.9266
Loa Loa (eye worm) hypothetical protein 0.031 0.0266 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0006 0.0006
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0108 0.007 0.0963
Loa Loa (eye worm) reprolysin 0.0089 0.0051 0.0051
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0041 0.0006 0.0006
Toxoplasma gondii type I fatty acid synthase, putative 0.0082 0.0045 0.1056
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0041 0.0006 0.0006
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0503 0.0453 0.0453
Echinococcus granulosus membrane bound transcription factor site 1 0.0456 0.0407 0.0406
Echinococcus multilocularis adam 0.0206 0.0165 0.0204
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0017 0.0024
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0066 0.003 0.0549
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0011 0.0013
Echinococcus granulosus protein kinase C gamma type 0.0041 0.0005 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Loa Loa (eye worm) hypothetical protein 0.0147 0.0108 0.0108
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0142 0.0103 0.2498
Mycobacterium tuberculosis Conserved hypothetical protein 0.0142 0.0103 0.2387
Brugia malayi ion channel NompC 0.0041 0.0006 0.0006
Echinococcus multilocularis voltage dependent calcium channel 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus multilocularis integrin alpha ps 0.058 0.0528 0.0658
Echinococcus multilocularis rac serine:threonine kinase 0.0058 0.0021 0.0025
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.004 0.0004 0.006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Loa Loa (eye worm) hypothetical protein 0.0456 0.0407 0.0407
Echinococcus granulosus fibrillin 1 0.0092 0.0055 0.0053
Brugia malayi hypothetical protein 0.0072 0.0036 0.0036
Echinococcus granulosus glutamate NMDA receptor subunit 0.0265 0.0222 0.0221
Trypanosoma cruzi Protein kinase B 0.0058 0.0021 0.0235
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.0675 0.0674
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Mycobacterium ulcerans monoamine oxidase 0.0142 0.0103 0.2273
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0041 0.0006 0.0005
Loa Loa (eye worm) fatty acid synthase 0.0079 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Echinococcus granulosus potassium voltage gated channel protein 0.0041 0.0006 0.0005
Echinococcus granulosus two pore calcium channel protein 1 0.0041 0.0006 0.0005
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0038 0.0002 0.0002
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0058 0.0021 0.0477
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0056 0.002 0.0023
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0103 0.1457
Schistosoma mansoni serine/threonine-protein kinase 0.0058 0.0021 0.002
Toxoplasma gondii bicoid-interacting protein BIN3 0.0053 0.0017 0.0367
Loa Loa (eye worm) ryanodine receptor 0.0041 0.0006 0.0006
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0011 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) hypothetical protein 0.0037 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0044 0.0008 0.0009
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0053 0.0017 0.0168
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0041 0.0006 0.0006
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0041 0.0006 0.008
Echinococcus multilocularis sodium leak channel non selective protein 0.0041 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0732 0.0675 1
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0052 0.0016 0.0016
Loa Loa (eye worm) subtilase 0.0456 0.0407 0.0407
Echinococcus multilocularis potassium voltage gated channel protein 0.0041 0.0006 0.0006
Toxoplasma gondii transporter, cation channel family protein 0.0041 0.0006 0.0089
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0482 0.0432 0.6372
Echinococcus granulosus hypothetical protein 0.0041 0.0006 0.0005
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0108 0.007 0.1681
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0038 0.0002 0.0001
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0053 0.0017 0.002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0041 0.0006 0.0005
Brugia malayi EGF-like domain containing protein 0.0089 0.0052 0.0052
Onchocerca volvulus 0.0041 0.0006 0.008
Loa Loa (eye worm) hypothetical protein 0.0759 0.07 0.07
Giardia lamblia Hypothetical protein 0.0732 0.0675 0.1796
Echinococcus multilocularis integrin alpha ps 0.0248 0.0206 0.0256
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0456 0.0407 0.0507
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0006 0.0006
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0041 0.0006 0.0005
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0108 0.007 0.0069
Brugia malayi Subtilase family protein 0.0456 0.0407 0.0407
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0041 0.0006 0.0006
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0006 0.0006
Echinococcus multilocularis transfer RNA-Gly 0.0041 0.0006 0.0006
Echinococcus granulosus Protein kinase C brain isozyme 0.0048 0.0012 0.001
Brugia malayi Angiotensin-converting enzyme family protein 0.0622 0.0569 0.0569
Mycobacterium ulcerans dehydrogenase 0.0142 0.0103 0.2273
Schistosoma mansoni atypical protein kinase C 0.0046 0.001 0.0009
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0011 0.001
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0077 0.004 0.0812
Loa Loa (eye worm) voltage-gated calcium channel 0.0041 0.0006 0.0006
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0057 0.0056
Echinococcus multilocularis neuroendocrine convertase 2 0.6542 0.6305 0.7879
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0041 0.0006 0.0006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0011 0.0013
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0041 0.0006 0.0006
Echinococcus multilocularis ryanodine receptor 44f 0.0041 0.0006 0.0006
Schistosoma mansoni cathepsin D (A01 family) 0.0038 0.0002 0.0001
Brugia malayi voltage-dependent calcium channel 0.0041 0.0006 0.0006
Schistosoma mansoni glutamate receptor NMDA 0.0265 0.0222 0.0221
Brugia malayi amine oxidase, flavin-containing family protein 0.0201 0.016 0.016
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0732 0.0675 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0053 0.0017 0.0016
Giardia lamblia Transcriptional regulator, Sir2 family 0.0108 0.007 0.0134
Entamoeba histolytica protein kinase 2, putative 0.0058 0.0021 0.0263
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0058 0.0021 0.0025
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.008 0.0043 0.5
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0059 0.0023 0.0022
Brugia malayi Protein kinase domain containing protein 0.0096 0.0058 0.0058
Schistosoma mansoni integrin alpha-ps 0.0518 0.0467 0.0466
Echinococcus multilocularis protein will die slowly 0.0148 0.0109 0.0135
Echinococcus multilocularis potassium voltage gated channel protein 0.0041 0.0006 0.0006
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0058 0.0021 0.0477
Giardia lamblia hypothetical protein 0.0089 0.0052 0.0085
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.6331 0.61 0.7622
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0104 0.0067 0.0067
Onchocerca volvulus 0.0074 0.0038 0.0537
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0732 0.0675 0.0842
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0053 0.0017 0.0367
Echinococcus granulosus calcium activated potassium channel 0.0043 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0053 0.0017 0.0168
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0456 0.0407 0.5996
Echinococcus granulosus transient receptor potential gamma protein 0.0041 0.0006 0.0005
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0732 0.0675 1
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0004 0.0003
Echinococcus multilocularis potassium large conductance calcium activated 0.0041 0.0006 0.0006
Echinococcus granulosus voltage dependent calcium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis nmda type glutamate receptor 0.0112 0.0074 0.0091
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 1.0356 1 1
Brugia malayi Will die slowly protein 0.0148 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0103 0.2498
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Mycobacterium leprae Polyketide synthase Pks13 0.0116 0.0078 0.1762
Schistosoma mansoni hypothetical protein 0.2062 0.1963 0.1962
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0111 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0041 0.0006 0.0006
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.008 0.0043 0.0751
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0639 0.0584 0.0584
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0142 0.0103 0.2273
Echinococcus multilocularis protein arginine methyltransferase 0.0094 0.0057 0.007
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0108 0.007 0.0086
Echinococcus granulosus potassium large conductance calcium activated 0.0041 0.0006 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0058 0.0021 0.002
Schistosoma mansoni protein arginine n-methyltransferase 0.0053 0.0017 0.0016
Echinococcus granulosus serine/threonine protein kinase 0.0058 0.0021 0.002
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0045 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0008 0.0008
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0074 0.0038 0.0745
Echinococcus granulosus integrin alpha ps 0.058 0.0528 0.0527
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Entamoeba histolytica protein kinase, putative 0.0096 0.0058 0.081
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Schistosoma mansoni transient receptor potential channel 0.0041 0.0006 0.0005
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Echinococcus multilocularis protein kinase c iota type 0.0046 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0042 0.0006 0.0006
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0445 0.0396 0.0396
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0456 0.0407 1
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Toxoplasma gondii AGC kinase 0.0096 0.0058 0.1384
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0127 0.0089 0.011
Schistosoma mansoni transient receptor potential channel 4 0.0041 0.0006 0.0005
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0108 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0089 0.0052 0.0052
Brugia malayi GCC2 and GCC3 family protein 0.0044 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0053 0.0017 0.0016
Echinococcus granulosus serine:threonine protein kinase N2 0.0039 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0148 0.0109 0.0108
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0006 0.0005
Plasmodium vivax subtilisin-like protease 2, putative 0.0456 0.0407 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0148 0.0109 0.0109
Brugia malayi SWIRM domain containing protein 0.0059 0.0023 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0004 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.0407 0.0664
Leishmania major UDP-galactopyranose mutase 0.0142 0.0103 0.1457
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0041 0.0006 0.0006
Loa Loa (eye worm) integrin beta-2 0.3128 0.2997 0.2997
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0008 0.0145
Entamoeba histolytica hypothetical protein 0.0059 0.0023 0.0284
Loa Loa (eye worm) hypothetical protein 0.0038 0.0002 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0006 0.0005
Schistosoma mansoni ryanodine receptor related 0.0041 0.0006 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus granulosus nmda type glutamate receptor 0.0112 0.0074 0.0073
Echinococcus granulosus shaker cognate 0.0041 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Echinococcus granulosus discoidin domain receptor 0.0044 0.0008 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus lysine specific histone demethylase 1A 0.0142 0.0103 0.0102
Loa Loa (eye worm) hypothetical protein 0.0108 0.007 0.007
Toxoplasma gondii hypothetical protein 0.0041 0.0006 0.0089
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0057 0.009
Loa Loa (eye worm) hypothetical protein 0.0089 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0036
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0053 0.0017 0.0017
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0011 0.0013
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.008 0.0043 0.5
Echinococcus granulosus TRP transient receptor potential channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) TK/ALK protein kinase 0.0072 0.0036 0.0036
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0456 0.0407 1
Echinococcus granulosus protein arginine N methyltransferase 8 0.0094 0.0057 0.0056
Entamoeba histolytica protein kinase, putative 0.0096 0.0058 0.081
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0041 0.0006 0.0006
Echinococcus granulosus neuroendocrine convertase 2 0.6542 0.6305 0.6305
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0456 0.0407 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0041 0.0006 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0004 0.0003
Mycobacterium ulcerans thioesterase TesA 0.0066 0.003 0.0407
Schistosoma mansoni vesicular amine transporter 0.0041 0.0006 0.0005
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0057 0.009
Brugia malayi transcriptional regulator, Sir2 family protein 0.0732 0.0675 0.0675
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0147 0.0108 0.1534
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0124 0.0086 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.0088 0.0087
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0041 0.0006 0.0006
Entamoeba histolytica SWIRM domain protein 0.0059 0.0023 0.0284
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0041 0.0006 0.0005
Brugia malayi aspartic protease BmAsp-2, identical 0.0038 0.0002 0.0002
Mycobacterium leprae Probable polyketide synthase Pks1 0.0082 0.0045 0.0924
Loa Loa (eye worm) sirtuin 4 0.0108 0.007 0.007
Trichomonas vaginalis hypothetical protein 0.2062 0.1963 0.3216
Loa Loa (eye worm) hypothetical protein 0.0059 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0012 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.0407 0.0664
Echinococcus granulosus protein kinase c epsilon type 0.0124 0.0086 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.0407 0.0664
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Onchocerca volvulus 0.0759 0.07 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0732 0.0675 0.0674
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0061 0.0025 0.0426
Brugia malayi Pepsin A precursor 0.0038 0.0002 0.0002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) hypothetical protein 0.0044 0.0008 0.0008
Mycobacterium tuberculosis Probable thioesterase TesA 0.0066 0.003 0.0549
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0041 0.0006 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0004 0.0002
Echinococcus multilocularis serine:threonine protein kinase N2 0.0116 0.0078 0.0096
Schistosoma mansoni amine oxidase 0.0142 0.0103 0.0102
Loa Loa (eye worm) proprotein convertase 2 0.2517 0.2405 0.2405
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Echinococcus multilocularis protoporphyrinogen oxidase 0.0142 0.0103 0.0128
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0017 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) voltage-dependent calcium channel 0.0041 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis shaker cognate 0.0041 0.0006 0.0006
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0039 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0699 0.0643 0.0643
Brugia malayi Protein kinase domain containing protein 0.0072 0.0036 0.0036
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0108 0.007 0.0963
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0456 0.0407 1
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0142 0.0103 0.2498
Echinococcus granulosus adam 0.0206 0.0165 0.0164
Loa Loa (eye worm) calcium channel 0.0041 0.0006 0.0006
Schistosoma mansoni SWI/SNF complex-related 0.0059 0.0023 0.0022
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0265 0.0222 0.0276
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0073 0.0036 0.0035
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0044 0.0008 0.001
Plasmodium falciparum protoporphyrinogen oxidase 0.0142 0.0103 0.2498
Entamoeba histolytica protein kinase, putative 0.0096 0.0058 0.081
Mycobacterium ulcerans thioesterase 0.0066 0.003 0.0407
Entamoeba histolytica PH domain containing protein kinase, putative 0.0058 0.0021 0.0263
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0082 0.0045 0.0924
Brugia malayi Sex muscle abnormal protein 5 0.0126 0.0088 0.0088
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0077 0.004 0.0804
Giardia lamblia Neurogenic locus notch-like protein 0.0089 0.0052 0.0085
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0041 0.0006 0.0006
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0039 0.0004 0.0003
Schistosoma mansoni discoidin domain receptor 0.0044 0.0008 0.0007
Entamoeba histolytica hypothetical protein, conserved 0.0108 0.007 0.0989
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0053 0.0017 0.0017
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0041 0.0006 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0039 0.0004 0.0003
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0039 0.0004 0.0003
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0142 0.0103 0.0102
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Loa Loa (eye worm) transcriptional regulator 0.0108 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0023 0.0034
Brugia malayi Integrin alpha pat-2 precursor 0.0963 0.0898 0.0898
Echinococcus multilocularis potassium voltage gated channel protein 0.0041 0.0006 0.0006
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0089 0.0051 0.0063
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0082 0.0045 0.0924
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0057 0.0021 0.0326
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.007 0.007
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.067 0.0614 0.0613
Mycobacterium tuberculosis Possible oxidoreductase 0.0142 0.0103 0.2387
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.007 0.0069
Brugia malayi NAD-dependent deacetylase SIRT1 0.0108 0.007 0.007
Echinococcus granulosus NDR protein kinase 0.0039 0.0004 0.0003
Echinococcus multilocularis membrane bound transcription factor site 1 0.0456 0.0407 0.0507
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0006 0.0006
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0482 0.0432 0.6372
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Schistosoma mansoni dock 0.0044 0.0008 0.0007
Schistosoma mansoni amine oxidase 0.0142 0.0103 0.0102
Toxoplasma gondii subtilisin SUB10 0.0456 0.0407 1
Echinococcus multilocularis two pore calcium channel protein 1 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0699 0.0643 0.0643
Echinococcus multilocularis two pore calcium channel protein 2 0.0041 0.0006 0.0006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0058 0.0021 0.0263
Brugia malayi hypothetical protein 0.0116 0.0078 0.0078
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0006 0.0005
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0041 0.0006 0.0005
Mycobacterium ulcerans polyketide synthase 0.0082 0.0045 0.0788
Toxoplasma gondii subtilisin SUB6 0.0456 0.0407 1
Schistosoma mansoni integrin alpha 0.0963 0.0898 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Echinococcus multilocularis voltage gated potassium channel 0.0041 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0456 0.0407 0.0407
Echinococcus granulosus protein kinase c iota type 0.0046 0.001 0.0009
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0456 0.0407 1
Giardia lamblia Sirtuin type 2 0.0108 0.007 0.0134
Schistosoma mansoni hypothetical protein 0.0072 0.0036 0.0035
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0041 0.0006 0.0005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0006 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0041 0.0006 0.0006
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0231 0.0189 0.0189
Echinococcus multilocularis integrin alpha ps 0.0518 0.0467 0.0583
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0039 0.0004 0.0003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0077 0.004 0.0804
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0041 0.0006 0.0006
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0456 0.0407 1
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0041 0.0006 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0096 0.0058 0.0058
Schistosoma mansoni memapsin-2 (A01 family) 0.0038 0.0002 0.0001
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0041 0.0006 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0041 0.0006 0.0005
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.004 0.0666
Brugia malayi Kelch motif family protein 0.0503 0.0453 0.0453
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0041 0.0006 0.0005
Toxoplasma gondii hypothetical protein 0.0089 0.0052 0.1238
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Schistosoma mansoni transient receptor potential channel 0.0041 0.0006 0.0005
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0089 0.0051 0.005
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0089 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0094 0.0057 0.1353
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0006 0.0005
Brugia malayi Cyclic-nucleotide gated cation channel 0.0041 0.0006 0.0006
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0008 0.0145
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0041 0.0006 0.0006
Mycobacterium ulcerans NAD-dependent deacetylase 0.0108 0.007 0.1432
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.004 0.0666
Onchocerca volvulus 0.0148 0.0109 0.1558
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0103 0.2498
Schistosoma mansoni hypothetical protein 0.0248 0.0206 0.0205
Schistosoma mansoni hypothetical protein 0.0044 0.0008 0.0007
Toxoplasma gondii PA14 domain-containing protein 0.0044 0.0008 0.0145
Loa Loa (eye worm) AGC/AKT protein kinase 0.0096 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Trypanosoma brucei rac serine-threonine kinase, putative 0.0096 0.0058 0.0784
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Schistosoma mansoni site-1 peptidase (S08 family) 0.0456 0.0407 0.0406
Echinococcus multilocularis protein kinase c epsilon type 0.0124 0.0086 0.0106
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.008 0.0043 0.0888
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0077 0.004 0.004
Echinococcus granulosus integrin beta 2 0.2314 0.2208 0.2207
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0041 0.0006 0.0006
Echinococcus granulosus serine threonine protein kinase nrc 0.0058 0.0021 0.002
Echinococcus granulosus voltage dependent calcium channel 0.0041 0.0006 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0041 0.0006 0.0006
Plasmodium falciparum subtilisin-like protease 3 0.0456 0.0407 1
Schistosoma mansoni voltage-dependent calcium channel 0.0041 0.0006 0.0005
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.2517 0.2405 0.2404
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0006 0.0005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0006 0.0006
Trypanosoma brucei SIR2-like protein 4, putative 0.0108 0.007 0.0963
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0053 0.0017 0.0367
Brugia malayi neuroendocrine convertase 1 precursor 0.6542 0.6305 0.6305
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0041 0.0006 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Onchocerca volvulus Fatty acid synthase homolog 0.0144 0.0105 0.1494
Brugia malayi protein kinase C II. 0.0124 0.0086 0.0086
Echinococcus multilocularis short transient receptor potential channel 6 0.0041 0.0006 0.0006
Echinococcus granulosus glutamate receptor 2 0.0047 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0116 0.0078 0.1762
Brugia malayi hypothetical protein 0.0142 0.0103 0.0103
Leishmania major arginine N-methyltransferase, type I 0.0053 0.0017 0.0168
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0231 0.0189 0.0235
Giardia lamblia hypothetical protein 0.0059 0.0023 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Echinococcus multilocularis serine:threonine protein kinase 38 0.0039 0.0004 0.0003
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0456 0.0407 1
Brugia malayi hypothetical protein 0.0041 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0147 0.0108 0.1559
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0008 0.0009
Plasmodium falciparum subtilisin-like protease 1 0.0456 0.0407 1
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0089 0.0052 0.0082
Mycobacterium ulcerans oxidoreductase 0.0142 0.0103 0.2273
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0006 0.0005
Echinococcus multilocularis protein jagged 2 0.0089 0.0052 0.0064
Loa Loa (eye worm) ion channel NompC 0.0041 0.0006 0.0006
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0108 0.007 0.1681
Onchocerca volvulus 0.0139 0.01 0.1426
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0456 0.0407 0.0406
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0041 0.0006 0.0005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0112 0.0074 0.0091
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0008 0.0145
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0056 0.002 0.0019
Echinococcus multilocularis fibrillin 1 0.0092 0.0055 0.0067
Giardia lamblia Furin precursor putative serine protease 0.2062 0.1963 0.5336
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0039 0.0004 0.0003
Onchocerca volvulus 0.0044 0.0008 0.0113
Echinococcus multilocularis serine threonine protein kinase 0.0041 0.0005 0.0005
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0082 0.0045 0.0924
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) endoprotease bli-4 1.0356 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Toxoplasma gondii type I fatty acid synthase, putative 0.0057 0.002 0.0454
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0699 0.0643 0.0802
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0041 0.0006 0.0005
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0041 0.0006 0.008
Echinococcus granulosus serine:threonine protein kinase N2 0.0078 0.0041 0.004
Schistosoma mansoni integrin alpha-ps 0.0332 0.0287 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Brugia malayi EGF-like domain containing protein 0.0089 0.0052 0.0052
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Toxoplasma gondii subtilisin SUB2 0.0456 0.0407 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0041 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Toxoplasma gondii histone deacetylase SIR2 0.0108 0.007 0.1681
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0147 0.0108 0.1559
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0142 0.0103 0.2498
Loa Loa (eye worm) voltage-gated potassium channel 0.0041 0.0006 0.0006
Toxoplasma gondii aspartyl protease ASP5 0.0387 0.0341 0.8362
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0053 0.0017 0.0016
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0699 0.0643 0.0642
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0044 0.0008 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0059 0.0023 0.0027
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0038 0.0002 0.0001
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0622 0.0569 0.0569
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0041 0.0006 0.0005
Brugia malayi Furin-like cysteine rich region family protein 0.0652 0.0597 0.0597
Brugia malayi proprotein convertase 2 0.6542 0.6305 0.6305
Giardia lamblia High cysteine membrane protein Group 2 0.3813 0.366 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0002 0.0002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0108 0.007 0.0086
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Loa Loa (eye worm) transcriptional regulator 0.0732 0.0675 0.0675
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0041 0.0006 0.0006
Echinococcus granulosus protein will die slowly 0.0148 0.0109 0.0108
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0103 0.1457
Echinococcus granulosus voltage gated potassium channel 0.0041 0.0006 0.0005
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.2062 0.1963 0.3216
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0006 0.0005
Leishmania major silent information regulator 2, putative 0.0732 0.0675 1
Toxoplasma gondii subtilisin SUB11 0.0456 0.0407 1
Plasmodium falciparum subtilisin-like protease 2 0.0456 0.0407 1
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0052 0.0016 0.0334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0038 0.0002 0.0002
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0142 0.0103 0.2387
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0094 0.0057 0.009
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0058 0.0021 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Brugia malayi EGF-like domain containing protein 0.0089 0.0052 0.0052
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0108 0.007 0.0134
Echinococcus multilocularis voltage gated potassium channel 0.0041 0.0006 0.0006
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0108 0.007 0.0086
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus multilocularis discoidin domain receptor 0.0044 0.0008 0.0009
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0482 0.0432 0.6372
Schistosoma mansoni serine/threonine kinase 0.0039 0.0004 0.0003
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0456 0.0407 1
Schistosoma mansoni protein kinase 0.0127 0.0089 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0006 0.0006
Schistosoma mansoni furin-1 (S08 family) 0.4481 0.4307 0.4307
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0023 0.0034
Echinococcus granulosus protein arginine N methyltransferase 7 0.0053 0.0017 0.0016
Toxoplasma gondii transporter, cation channel family protein 0.0041 0.0006 0.0089
Echinococcus multilocularis growth factor receptor bound protein 2 0.0126 0.0088 0.0108
Echinococcus granulosus Glutaredoxin protein 5 0.0056 0.002 0.0019
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0006 0.0005
Brugia malayi Integrin beta pat-3 precursor 0.3128 0.2997 0.2997
Toxoplasma gondii subtilisin SUB5 0.0456 0.0407 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) hypothetical protein 0.0142 0.0103 0.0103
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0142 0.0103 0.0103
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.6331 0.61 0.6099
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.004 0.0804
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0006 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Brugia malayi ADAM-TS Spacer 1 family protein 0.0052 0.0016 0.0016
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0077 0.004 0.0804
Echinococcus multilocularis transient receptor potential gamma protein 0.0041 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0006 0.0005
Echinococcus granulosus two pore calcium channel protein 2 0.0041 0.0006 0.0005
Giardia lamblia Tenascin-like 0.0089 0.0052 0.0085
Schistosoma mansoni integrin beta subunit 0.1837 0.1746 0.1745
Schistosoma mansoni calcium-activated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus furin 1.0356 1 1
Schistosoma mansoni hypothetical protein 0.0041 0.0006 0.0005
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.0675 0.0674
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0077 0.004 0.0812
Echinococcus multilocularis nervana 2 0.0056 0.002 0.0023
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0116 0.0078 0.1762
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0127 0.0089 0.0088
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0732 0.0675 0.1103
Loa Loa (eye worm) hypothetical protein 0.0089 0.0052 0.0052
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0006 0.0006
Trichomonas vaginalis hypothetical protein 0.0044 0.0008 0.001
Brugia malayi Carm1-pending protein 0.0053 0.0017 0.0017
Toxoplasma gondii transporter, cation channel family protein 0.0041 0.0006 0.0089
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0008 0.0145
Giardia lamblia Neurogenic locus Notch protein precursor 0.0089 0.0052 0.0085
Toxoplasma gondii hypothetical protein 0.0041 0.0006 0.0089
Echinococcus multilocularis fibrillin 2 0.0089 0.0052 0.0064
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Mycobacterium ulcerans polyketide synthase 0.0077 0.004 0.0666
Echinococcus multilocularis integrin beta 2 0.2314 0.2208 0.2758
Loa Loa (eye worm) hypothetical protein 0.0044 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Leishmania major sir2-family protein-like protein 0.0108 0.007 0.0963
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0053 0.0017 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0147 0.0108 0.1534
Echinococcus multilocularis Glutaredoxin protein 5 0.0056 0.002 0.0023
Toxoplasma gondii subtilisin SUB7 0.0456 0.0407 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0652 0.0597 0.0597
Schistosoma mansoni two-pore calcium channel 0.0041 0.0006 0.0005
Toxoplasma gondii subtilisin SUB4 0.0456 0.0407 1
Loa Loa (eye worm) hypothetical protein 0.0639 0.0584 0.0584
Mycobacterium ulcerans polyketide synthase Pks13 0.0116 0.0078 0.1638
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0111 0.0073 0.0073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0041 0.0006 0.0089
Loa Loa (eye worm) hypothetical protein 0.0089 0.0051 0.0051
Brugia malayi Transient-receptor-potential like protein 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0094 0.0057 0.007
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0089 0.0051 0.005
Giardia lamblia High cysteine protein 0.0089 0.0052 0.0085
Loa Loa (eye worm) apoptosis regulator protein 0.0053 0.0017 0.0017
Brugia malayi Reprolysin 0.0052 0.0016 0.0016
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0103 0.2273
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.007 0.0069
Brugia malayi aspartic protease BmAsp-1, identical 0.0038 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Onchocerca volvulus 0.0038 0.0002 0.0029
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0008 0.0007
Onchocerca volvulus 0.0176 0.0136 0.1939
Echinococcus multilocularis voltage dependent calcium channel 0.0041 0.0006 0.0006
Brugia malayi ADAMTS-like protease 0.0052 0.0016 0.0016
Loa Loa (eye worm) aspartyl protease 6 0.0038 0.0002 0.0002
Onchocerca volvulus 0.0044 0.0008 0.0113
Schistosoma mansoni glutamate receptor NMDA 0.0047 0.0011 0.001
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0041 0.0006 0.0005
Brugia malayi Protein arginine N-methyltransferase 0.0053 0.0017 0.0017
Echinococcus granulosus potassium voltage gated channel protein 0.0041 0.0006 0.0005
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0008 0.0009
Schistosoma mansoni hypothetical protein 0.0072 0.0036 0.0035
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0053 0.0017 0.0016
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.007 0.0069
Schistosoma mansoni discoidin domain receptor 0.0044 0.0008 0.0007
Brugia malayi hypothetical protein 0.0038 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis potassium voltage gated channel protein 0.0041 0.0006 0.0006
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0094 0.0057 0.1353
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0732 0.0675 0.1103
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0061 0.0025 0.0282
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0456 0.0407 0.0406
Loa Loa (eye worm) transcriptional regulator 0.0108 0.007 0.007
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0008 0.0145
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Giardia lamblia Tenascin-X 0.0089 0.0052 0.0085
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0053 0.0017 0.002
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0094 0.0057 0.0056
Echinococcus granulosus chromatin regulatory protein sir2 0.0732 0.0675 0.0674
Toxoplasma gondii histone deacetylase SIR2-like 0.0108 0.007 0.1681
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0488 0.0438 0.0437
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0732 0.0675 1
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0094 0.0057 0.1353
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0108 0.007 0.0069
Plasmodium vivax subtilisin-like serine protease, putative 0.0456 0.0407 1
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0044 0.0008 0.001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0074 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Schistosoma mansoni voltage-gated ion channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.2062 0.1963 0.3216
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0006 0.0006
Schistosoma mansoni septate junction protein 0.0053 0.0017 0.0016
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0041 0.0006 0.0005
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0039 0.0004 0.0004
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.004 0.0666
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0041 0.0006 0.0006
Brugia malayi Protein kinase domain containing protein 0.0039 0.0004 0.0004
Toxoplasma gondii F5/8 type C domain-containing protein 0.0044 0.0008 0.0145
Echinococcus multilocularis 0.8294 0.8002 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 1.0356 1 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0142 0.0103 0.2498
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Echinococcus granulosus nervana 2 0.0056 0.002 0.0019
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0041 0.0006 0.0006
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0456 0.0407 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0077 0.004 0.0804
Entamoeba histolytica SWIRM domain protein 0.0059 0.0023 0.0284
Echinococcus multilocularis epidermal growth factor receptor 0.0652 0.0597 0.0745
Giardia lamblia Tenascin-37 0.0089 0.0052 0.0085
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Loa Loa (eye worm) WD40 repeat protein 0.0148 0.0109 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0058 0.0092
Echinococcus granulosus c-Jun N-terminal kinases 0.0231 0.0189 0.0188
Echinococcus multilocularis nervana 2 0.0056 0.002 0.0023
Brugia malayi Hr1 repeat family protein 0.0039 0.0004 0.0004
Toxoplasma gondii histone lysine-specific demethylase 0.0142 0.0103 0.2498
Echinococcus multilocularis calcium activated potassium channel 0.0043 0.0007 0.0008
Trypanosoma brucei subtilisin peptidase 0.0456 0.0407 0.5996
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0041 0.0006 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0041 0.0006 0.0006
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0058 0.0021 0.0235
Onchocerca volvulus 0.0072 0.0036 0.0509
Echinococcus multilocularis discoidin domain containing receptor 2 0.0044 0.0008 0.0009
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0126 0.0088 0.0088
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.2517 0.2405 0.394
Plasmodium vivax LCCL domain-containing protein 0.0044 0.0008 0.0145
Loa Loa (eye worm) integrin alpha pat-2 0.1291 0.1217 0.1217
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus granulosus sodium leak channel non selective protein 0.0041 0.0006 0.0005
Echinococcus granulosus potassium voltage gated channel protein 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0089 0.0052 0.0052
Brugia malayi Eukaryotic aspartyl protease family protein 0.0038 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0016 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0041 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0041 0.0006 0.0005
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0053 0.0017 0.0168
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0082 0.0045 0.0788
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0039 0.0004 0.0003
Brugia malayi cation channel family protein 0.0041 0.0006 0.0006
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0039 0.0004 0.0003
Echinococcus multilocularis chromatin regulatory protein sir2 0.0732 0.0675 0.0842
Echinococcus granulosus Furin 1 0.2517 0.2405 0.2404
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0108 0.007 0.0989
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.007 0.0069
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0053 0.0017 0.0016
Trichomonas vaginalis WD repeat domain, putative 0.0148 0.0109 0.0176
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0041 0.0006 0.0005
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.0017 0.0024
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.4025 0.3866 0.3866
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0041 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus short transient receptor potential channel 6 0.0041 0.0006 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0006 0.0005
Echinococcus multilocularis short transient receptor potential channel 6 0.0041 0.0006 0.0006
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.0088 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0477 0.0428 0.0428
Echinococcus granulosus integrin alpha 3 0.0693 0.0637 0.0636
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0456 0.0407 0.0406
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Schistosoma mansoni site-1 peptidase (S08 family) 0.0456 0.0407 0.0406
Plasmodium vivax hypothetical protein, conserved 0.0108 0.007 0.1681
Echinococcus granulosus potassium voltage gated channel protein 0.0041 0.0006 0.0005
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0041 0.0006 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Brugia malayi cation channel family protein 0.0041 0.0006 0.0006
Toxoplasma gondii subtilisin SUB9 0.0456 0.0407 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0048 0.0012 0.0013
Echinococcus multilocularis 0.0142 0.0103 0.0128
Schistosoma mansoni voltage-gated cation channel 0.0041 0.0006 0.0005
Chlamydia trachomatis protoporphyrinogen oxidase 0.0142 0.0103 1
Leishmania major subtilisin-like serine peptidase 0.0456 0.0407 0.5996
Echinococcus granulosus potassium voltage gated channel protein 0.0041 0.0006 0.0005
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0044 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0332 0.0287 0.0287
Plasmodium falciparum plasmepsin V 0.0425 0.0377 0.9266
Mycobacterium ulcerans Sir2-like regulatory protein 0.0108 0.007 0.1432
Echinococcus granulosus epidermal growth factor receptor 0.0652 0.0597 0.0596
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0041 0.0006 0.0006
Echinococcus granulosus MAM 0.0072 0.0036 0.0035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus granulosus transient receptor potential cation channel 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0131 0.0092 0.0092
Toxoplasma gondii subtilisin SUB1 0.0456 0.0407 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.007 0.0112
Toxoplasma gondii subtilisin SUB12 0.0456 0.0407 1
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0108 0.007 0.0963
Brugia malayi Stress-activated protein kinase jnk-1 0.0231 0.0189 0.0189
Trichomonas vaginalis hypothetical protein 0.0089 0.0052 0.0082
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.2062 0.1963 0.3216
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.067 0.0614 0.0767
Echinococcus granulosus ryanodine receptor 44f 0.0041 0.0006 0.0005
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0041 0.0006 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0004 0.0003
Echinococcus multilocularis Furin 1 0.2517 0.2405 0.3004
Echinococcus multilocularis integrin alpha 3 0.0693 0.0637 0.0795
Brugia malayi Disintegrin family protein 0.0037 0.0001 0.0001
Schistosoma mansoni chromatin regulatory protein sir2 0.0732 0.0675 0.0674
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0108 0.007 0.1559
Echinococcus granulosus protein arginine methyltransferase 0.0094 0.0057 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0715 0.0658 0.0658
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0116 0.0078 0.0077
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6331 0.61 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0096 0.0058 0.0058
Brugia malayi angiogenesis inhibito 0.0052 0.0016 0.0016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Giardia lamblia Tenascin precursor 0.0089 0.0052 0.0085
Schistosoma mansoni hypothetical protein 0.0053 0.0017 0.0016
Onchocerca volvulus 0.0089 0.0052 0.0744
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0004 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0078 0.0041 0.0557
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0108 0.007 0.0963
Loa Loa (eye worm) hypothetical protein 0.0053 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.0407 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.0407 0.0664
Brugia malayi SWIRM domain containing protein 0.0759 0.07 0.07
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0732 0.0675 1
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.005 0.0014 0.0148
Mycobacterium leprae Possible secreted protease 0.0456 0.0407 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0061 0.0025 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0008 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0456 0.0407 0.0664
Echinococcus multilocularis sodium channel protein 0.0041 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6331 0.61 1
Schistosoma mansoni hypothetical protein 0.0053 0.0017 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0006 0.0005
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0041 0.0006 0.0005
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0047 0.0011 0.001
Brugia malayi olfactory channel protein osm-9 0.0041 0.0006 0.0006
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0041 0.0006 0.0005
Schistosoma mansoni apoptosis regulator bax 0.0053 0.0017 0.0016
Echinococcus granulosus voltage gated hydrogen channel 1 0.0041 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0002 0.0002
Loa Loa (eye worm) Carm1-pending protein 0.0053 0.0017 0.0017
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0058 0.0021 0.002
Echinococcus multilocularis transient receptor potential cation channel 0.0041 0.0006 0.0006
Brugia malayi celfurPC protein 0.8294 0.8002 0.8002
Echinococcus granulosus lysine specific histone demethylase 1A 0.0699 0.0643 0.0642
Onchocerca volvulus 0.0072 0.0036 0.0509
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0002 0.0001
Schistosoma mansoni protein kinase 0.0127 0.0089 0.0088
Echinococcus granulosus discoidin domain containing receptor 2 0.0044 0.0008 0.0007
Echinococcus granulosus fibrillin 2 0.0089 0.0052 0.0051
Echinococcus multilocularis MAM 0.0072 0.0036 0.0043
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0082 0.0045 0.0924
Echinococcus granulosus voltage gated potassium channel 0.0041 0.0006 0.0005
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0006 0.0006
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0103 0.2273
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0039 0.0004 0.0004

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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