Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein kinase c iota type | 0.0713 | 0.1447 | 0.4975 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0786 | 0.1681 | 0.5781 |
Entamoeba histolytica | protein kinase, putative | 0.0372 | 0.0353 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0786 | 0.1681 | 0.5781 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0372 | 0.0353 | 0.1215 |
Entamoeba histolytica | protein kinase, putative | 0.0372 | 0.0353 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.327 | 0.9647 | 0.9647 |
Brugia malayi | protein kinase C3,putative | 0.0351 | 0.0287 | 0.1641 |
Echinococcus granulosus | unc 13 munc13 | 0.028 | 0.0061 | 0.0208 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0713 | 0.1447 | 0.4975 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0372 | 0.0353 | 0.2021 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0517 | 0.0818 | 0.2812 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.028 | 0.0061 | 0.0208 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0271 | 0.0032 | 0.0109 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0357 | 0.0306 | 0.0306 |
Schistosoma mansoni | atypical protein kinase C | 0.0719 | 0.1466 | 0.504 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0372 | 0.0353 | 0.0353 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.1169 | 0.2908 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.1169 | 0.2908 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1169 | 0.2908 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1169 | 0.2908 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3009 | 0.8808 | 0.8808 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0372 | 0.0353 | 0.1215 |
Brugia malayi | Protein kinase domain containing protein | 0.0271 | 0.0032 | 0.018 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Brugia malayi | C1-like domain containing protein | 0.0271 | 0.0032 | 0.018 |
Onchocerca volvulus | 0.028 | 0.0061 | 0.0069 | |
Schistosoma mansoni | unc-13 (munc13) | 0.028 | 0.0061 | 0.0208 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0372 | 0.0353 | 0.1215 |
Schistosoma mansoni | protein kinase C mu | 0.0271 | 0.0032 | 0.0109 |
Schistosoma mansoni | serine/threonine kinase | 0.0372 | 0.0353 | 0.1215 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0372 | 0.0353 | 0.1215 |
Echinococcus granulosus | protein kinase C gamma type | 0.0907 | 0.207 | 0.7118 |
Brugia malayi | Hr1 repeat family protein | 0.0372 | 0.0353 | 0.2021 |
Loa Loa (eye worm) | hypothetical protein | 0.0778 | 0.1656 | 0.1656 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0372 | 0.0353 | 0.0353 |
Schistosoma mansoni | protein kinase C | 0.028 | 0.0061 | 0.0208 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0372 | 0.0353 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Toxoplasma gondii | AGC kinase | 0.0372 | 0.0353 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0372 | 0.0353 | 0.1215 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0517 | 0.0818 | 0.2812 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0271 | 0.0032 | 0.0032 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0372 | 0.0353 | 0.1215 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0786 | 0.1681 | 0.1681 |
Entamoeba histolytica | protein kinase, putative | 0.0372 | 0.0353 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0372 | 0.0353 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.0818 | 0.0818 |
Brugia malayi | Protein kinase domain containing protein | 0.0372 | 0.0353 | 0.2021 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0271 | 0.0032 | 0.0109 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0271 | 0.0032 | 0.0109 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0372 | 0.0353 | 0.0353 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0372 | 0.0353 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0061 | 0.0061 |
Brugia malayi | Protein kinase c protein 2 | 0.0807 | 0.1748 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0372 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0372 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0372 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0545 | 0.091 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.3009 | 0.8808 | 0.8808 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.028 | 0.0061 | 0.0208 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0372 | 0.0353 | 0.1215 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0372 | 0.0353 | 0.1215 |
Brugia malayi | Protein kinase domain containing protein | 0.0372 | 0.0353 | 0.2021 |
Trichomonas vaginalis | AGC family protein kinase | 0.0372 | 0.0353 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0372 | 0.0353 | 0.2021 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0372 | 0.0353 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.3009 | 0.8808 | 0.8808 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0786 | 0.1681 | 0.5781 |
Entamoeba histolytica | protein kinase, putative | 0.0372 | 0.0353 | 1 |
Schistosoma mansoni | unc-13 (munc13) | 0.028 | 0.0061 | 0.0208 |
Echinococcus multilocularis | unc 13 (munc13) | 0.028 | 0.0061 | 0.0208 |
Brugia malayi | protein kinase C II. | 0.0786 | 0.1681 | 0.9617 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0517 | 0.0818 | 0.2812 |
Echinococcus multilocularis | death associated protein kinase 1 | 0.083 | 0.1823 | 0.6269 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0271 | 0.0032 | 0.0109 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0506 | 0.0783 | 0.2691 |
Onchocerca volvulus | 0.3009 | 0.8808 | 1 | |
Echinococcus multilocularis | serine threonine protein kinase | 0.0907 | 0.207 | 0.7118 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0372 | 0.0353 | 0.1215 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0372 | 0.0353 | 0.1215 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0372 | 0.0353 | 0.0353 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0271 | 0.0032 | 0.018 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0372 | 0.0353 | 0.1215 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.