Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | 0.0112 | 1 | 1 | |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0112 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0112 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Dopamine receptor protein 2 | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Dopamine receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Melatonin receptor type 1A | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Dopamine receptor protein 1 | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0112 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0062 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0112 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0112 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0112 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0062 | 0 | 0.5 |
Brugia malayi | larval opioid receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0112 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0112 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0112 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 1 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0112 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0112 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0112 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0112 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0112 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0112 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0112 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Trypanosoma brucei | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | steroid hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0094 | 0.6348 | 0.6348 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | ORL1-like opioid receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | follicle stimulating hormone receptor | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0112 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0112 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0112 | 1 | 1 |
Brugia malayi | RE15519p | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0112 | 1 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0094 | 0.6348 | 0.6348 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G protein-coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.