Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | AKH receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0112 | 1 | 1 |
Brugia malayi | Dopamine receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | coup transcription factor | 0.0112 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0112 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0112 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0062 | 0 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Onchocerca volvulus | 0.0112 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0112 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0112 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0112 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | ORL1-like opioid receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | RE15519p | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0112 | 1 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0112 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0112 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0062 | 0 | 0.5 |
Trypanosoma brucei | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0112 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0112 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0112 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0112 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0112 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0112 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | steroid hormone receptor | 0.0112 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0112 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0062 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0112 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0112 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0112 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0112 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Dopamine receptor protein 2 | 0.0094 | 0.6348 | 0.6348 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0112 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0112 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0112 | 1 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | follicle stimulating hormone receptor | 0.0094 | 0.6348 | 0.6348 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | nuclear hormone receptor | 0.0112 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | GnHR receptor homolog | 0.0094 | 0.6348 | 0.6348 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0112 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.6348 | 0.6348 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.