Detailed information for compound 828366

Basic information

Technical information
  • TDR Targets ID: 828366
  • Name: 1-[(2-fluorophenyl)methyl]-2,5-dimethyl-4-[(3 -methylbutylamino)methyl]pyrrole-3-carboxylic acid
  • MW: 346.439 | Formula: C20H27FN2O2
  • H donors: 2 H acceptors: 2 LogP: 1.46 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCNCc1c(C)n(c(c1C(=O)O)C)Cc1ccccc1F)C
  • InChi: 1S/C20H27FN2O2/c1-13(2)9-10-22-11-17-14(3)23(15(4)19(17)20(24)25)12-16-7-5-6-8-18(16)21/h5-8,13,22H,9-12H2,1-4H3,(H,24,25)
  • InChiKey: KJDJACAIYCSIEG-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[(2-fluorophenyl)methyl]-4-[(isopentylamino)methyl]-2,5-dimethyl-pyrrole-3-carboxylic acid
  • 1-[(2-fluorophenyl)methyl]-4-[(isopentylamino)methyl]-2,5-dimethyl-3-pyrrolecarboxylic acid
  • 1-(2-fluorobenzyl)-4-[(isoamylamino)methyl]-2,5-dimethyl-pyrrole-3-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Brugia malayi neuropeptide F receptor 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Onchocerca volvulus Neuropeptide F receptor homolog 0.0062 0.4093 0.5
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0059 0.3603 0.5699
Schistosoma mansoni histamine h1 receptor 0.0062 0.4093 0.6475
Brugia malayi G-protein coupled receptor 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptide FF receptor 2 0.0062 0.4093 0.6475
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.4979 0.4979
Schistosoma mansoni hypothetical protein 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptides capa receptor 0.0062 0.4093 0.6475
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 1 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0076 0.6322 1
Onchocerca volvulus 0.0062 0.4093 0.5
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis allatostatin A receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis g protein coupled receptor 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0059 0.3603 0.5699
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis G protein coupled receptor 139 0.0062 0.4093 0.6475
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptide receptor 0.0062 0.4093 0.6475
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.4093 0.6475
Brugia malayi G protein-coupled receptor F59B2.13 0.0062 0.4093 0.4093
Schistosoma mansoni alpha-1 adrenergic receptor 0.0062 0.4093 0.6475
Brugia malayi putative neuropeptide receptor 0.0062 0.4093 0.4093
Schistosoma mansoni amine GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus alpha 1A adrenergic receptor 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0062 0.4093 0.6475
Echinococcus granulosus g protein coupled receptor 0.0062 0.4093 0.6475
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0076 0.6322 1
Schistosoma mansoni amine GPCR 0.0062 0.4093 0.6475
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0076 0.6322 1
Brugia malayi sulfakinin receptor protein 0.0062 0.4093 0.4093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis neuropeptide receptor 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Toxoplasma gondii proteasome subunit beta type, putative 0.0076 0.6322 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0062 0.4093 0.6475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Loa Loa (eye worm) neuropeptide F receptor 0.0062 0.4093 0.4093
Schistosoma mansoni neuropeptide receptor 0.0062 0.4093 0.6475
Plasmodium vivax proteasome subunit beta type-5, putative 0.0076 0.6322 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptides capa receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0062 0.4093 0.6475
Brugia malayi RE15519p 0.0062 0.4093 0.4093
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0062 0.4093 0.6475
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0062 0.4093 0.4093
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0062 0.4093 0.4093
Echinococcus granulosus dro:myosuppressin receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis neuropeptide receptor 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Leishmania major proteasome beta 5 subunit, putative 0.0076 0.6322 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0062 0.4093 0.6475
Schistosoma mansoni neuropeptide F-like receptor 0.0062 0.4093 0.6475
Echinococcus granulosus biogenic amine 5HT receptor 0.0062 0.4093 0.6475
Schistosoma mansoni opsin-like receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Giardia lamblia Proteasome subunit beta type 1 0.0059 0.3603 0.5699
Echinococcus multilocularis dro:myosuppressin receptor 0.0062 0.4093 0.6475
Brugia malayi G-protein coupled receptor 0.0062 0.4093 0.4093
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0062 0.4093 0.6475
Brugia malayi ORL1-like opioid receptor 0.0062 0.4093 0.4093
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis g protein coupled receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis neuropeptide s receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis fmrfamide receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine (5HT) receptor 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0062 0.4093 0.6475
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0059 0.3603 0.5699
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Plasmodium falciparum proteasome subunit beta type-5 0.0076 0.6322 1
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0076 0.6322 0.5
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0062 0.4093 0.4093
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Schistosoma mansoni neuropeptide receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0062 0.4093 0.6475
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0062 0.4093 0.6475
Echinococcus granulosus 7TM GPCR rhodopsin 0.0062 0.4093 0.6475
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptide receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Trypanosoma brucei proteasome beta 6 subunit 0.0059 0.3603 0.5699
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0062 0.4093 0.4093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0059 0.3603 0.5699
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0062 0.4093 0.6475
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0062 0.4093 0.4093
Echinococcus multilocularis neuropeptides capa receptor 0.0062 0.4093 0.6475
Plasmodium vivax proteasome subunit beta type-1, putative 0.0059 0.3603 0.5699
Brugia malayi Tachykinin-like peptides receptor 99D 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Echinococcus granulosus biogenic amine 5HT receptor 0.0062 0.4093 0.6475
Brugia malayi follicle stimulating hormone receptor 0.0062 0.4093 0.4093
Echinococcus granulosus orexin receptor type 2 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0062 0.4093 0.6475
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.4093 0.6475
Echinococcus multilocularis g-protein coupled receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus proteasome prosome macropain 0.0076 0.6322 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Schistosoma mansoni growth hormone secretagogue receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni biogenic amine (5HT) receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus somatostatin receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine receptor 0.0062 0.4093 0.6475
Brugia malayi Dopamine receptor protein 1 0.0062 0.4093 0.4093
Schistosoma mansoni opsin-like receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) melatonin receptor type 1A 0.0062 0.4093 0.4093
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0062 0.4093 0.6475
Schistosoma mansoni amine GPCR 0.0062 0.4093 0.6475
Brugia malayi AKH receptor 0.0062 0.4093 0.4093
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0076 0.6322 1
Echinococcus multilocularis proteasome (prosome, macropain) 0.0076 0.6322 1
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.4093 0.6475
Echinococcus granulosus g-protein coupled receptor 0.0062 0.4093 0.6475
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0062 0.4093 0.5
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis somatostatin receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine receptor 0.0062 0.4093 0.6475
Echinococcus granulosus sex peptide receptor 0.0062 0.4093 0.6475
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0076 0.6322 1
Echinococcus multilocularis orexin receptor type 2 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Onchocerca volvulus 0.0062 0.4093 0.5
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0076 0.6322 0.5
Echinococcus granulosus allatostatin A receptor 0.0062 0.4093 0.6475
Schistosoma mansoni myosin xvIII 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Brugia malayi proteasome subunit beta type 1 0.0059 0.3603 0.3603
Echinococcus multilocularis serotonin receptor 0.0062 0.4093 0.6475
Brugia malayi Melatonin receptor type 1A 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0067 0.4979 0.4979
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus neuropeptide Y receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) G-protein coupled receptor 0.0062 0.4093 0.4093
Brugia malayi GnHR receptor homolog 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis G-protein coupled receptor, putative 0.0062 0.4093 0.6475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0059 0.3603 0.5699
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.4093 0.6475
Loa Loa (eye worm) G-protein coupled receptor 0.0062 0.4093 0.4093
Schistosoma mansoni hypothetical protein 0.0062 0.4093 0.6475
Echinococcus multilocularis g protein coupled receptor 0.0062 0.4093 0.6475
Echinococcus granulosus peptide allatostatin:somatostatin 0.0062 0.4093 0.6475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Schistosoma mansoni amine GPCR 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) proteasome subunit beta type 1 0.0059 0.3603 0.3603
Echinococcus multilocularis neuropeptide receptor A26 0.0062 0.4093 0.6475
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0076 0.6322 1
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0059 0.3603 0.5699
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0062 0.4093 0.4093
Schistosoma mansoni opsin-like receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis sex peptide receptor 0.0062 0.4093 0.6475
Schistosoma mansoni biogenic amine receptor 0.0062 0.4093 0.6475
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0059 0.3603 0.5699
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0062 0.4093 0.6475
Brugia malayi Dopamine receptor protein 2 0.0062 0.4093 0.4093
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0062 0.4093 0.6475
Echinococcus multilocularis neuropeptide Y receptor 0.0062 0.4093 0.6475
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0062 0.4093 0.6475
Brugia malayi Dopamine receptor 0.0062 0.4093 0.4093
Schistosoma mansoni neuropeptide receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni hypothetical protein 0.0062 0.4093 0.6475
Brugia malayi putative neuropeptide receptor NPR1 0.0062 0.4093 0.4093
Echinococcus granulosus hypothetical protein 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Schistosoma mansoni neuropeptide F-like receptor 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptide receptor A26 0.0062 0.4093 0.6475
Loa Loa (eye worm) TYRA-2 protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0062 0.4093 0.6475
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0099 1 1
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0059 0.3603 0.5699
Schistosoma mansoni amine GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus serotonin receptor 0.0062 0.4093 0.6475
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0076 0.6322 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0062 0.4093 0.6475
Echinococcus multilocularis serotonin receptor 0.0062 0.4093 0.6475
Schistosoma mansoni adenoreceptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Brugia malayi larval opioid receptor 0.0062 0.4093 0.4093
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Echinococcus granulosus neuropeptide Y receptor 0.0062 0.4093 0.6475
Echinococcus granulosus 7tm_1 domain containing protein 0.0062 0.4093 0.6475
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0059 0.3603 0.5699
Echinococcus multilocularis neuropeptides capa receptor 0.0062 0.4093 0.6475
Echinococcus granulosus fmrfamide receptor 0.0062 0.4093 0.6475
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0062 0.4093 0.6475
Brugia malayi hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Brugia malayi G protein-coupled receptor 0.0062 0.4093 0.4093
Schistosoma mansoni hypothetical protein 0.0062 0.4093 0.6475
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0059 0.3603 0.5699
Echinococcus granulosus g protein coupled receptor 0.0062 0.4093 0.6475
Onchocerca volvulus 0.0062 0.4093 0.5
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0062 0.4093 0.6475
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Brugia malayi neuropeptide F receptor 0.0062 0.4093 0.4093
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0062 0.4093 0.6475
Loa Loa (eye worm) neuropeptide F receptor 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Echinococcus granulosus neuropeptide s receptor 0.0062 0.4093 0.6475
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0062 0.4093 0.4093
Onchocerca volvulus 0.0062 0.4093 0.5
Brugia malayi Serotonin receptor 0.0062 0.4093 0.4093
Loa Loa (eye worm) hypothetical protein 0.0062 0.4093 0.4093
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0076 0.6322 0.6322
Echinococcus granulosus G protein coupled receptor 139 0.0062 0.4093 0.6475
Schistosoma mansoni hypothetical protein 0.0067 0.4979 0.7875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.4093 0.6475
Mycobacterium ulcerans proteasome PrcB 0.0076 0.6322 0.5
Echinococcus granulosus g protein coupled receptor 0.0062 0.4093 0.6475
Schistosoma mansoni neuropeptide receptor 0.0062 0.4093 0.6475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.4093 0.6475
Echinococcus multilocularis neuropeptide Y receptor 0.0062 0.4093 0.6475
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0062 0.4093 0.6475
Brugia malayi Proteasome A-type and B-type family protein 0.0076 0.6322 0.6322
Brugia malayi Serotonin receptor 0.0062 0.4093 0.4093
Echinococcus multilocularis fmrfamide receptor 0.0062 0.4093 0.6475

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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