Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.0036 | 0.0101 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0208 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0208 | 0.0587 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0832 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0194 | 0.0774 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0039 | 0.0039 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0024 | 0.0218 | 0.0871 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0306 | 0.1221 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0218 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0439 | 0.0439 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0439 | 0.1753 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.011 | 0.011 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.273 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0482 | 0.1926 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0104 | 0.0414 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0361 | 0.1017 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0306 | 0.1221 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0212 | 0.256 | 0.7188 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0104 | 0.0291 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Giardia lamblia | Phosphoglycerate kinase | 0.0085 | 0.0972 | 0.2664 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.011 | 0.011 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0024 | 0.0218 | 0.0218 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.0036 | 0.0101 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0104 | 0.0291 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0126 | 0.0126 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | dihydrofolate reductase | 0.0085 | 0.097 | 0.3873 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0031 | 0.0302 | 0.0848 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0271 | 0.1082 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0039 | 0.0156 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0134 | 0.0376 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0292 | 0.3561 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0292 | 0.3561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.0832 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0439 | 0.1753 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0482 | 0.1926 |
Echinococcus multilocularis | nibrin | 0.001 | 0.0036 | 0.0036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0793 | 0.3167 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0104 | 0.0414 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0099 | 0.1146 | 0.3229 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0039 | 0.0156 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0585 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0306 | 0.1221 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0134 | 0.0376 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.011 | 0.011 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0134 | 0.0534 |
Brugia malayi | Phosphoglycerate kinase | 0.0031 | 0.0302 | 0.1206 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0306 | 0.1221 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.273 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.042 | 0.1678 |
Echinococcus multilocularis | thymidylate synthase | 0.0208 | 0.2504 | 0.2504 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0285 | 0.1137 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0039 | 0.0156 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0134 | 0.1046 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0306 | 0.1221 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0585 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.3881 |
Onchocerca volvulus | 0.0236 | 0.286 | 1 | |
Toxoplasma gondii | phosphoglycerate kinase PGKII | 0.0085 | 0.0972 | 0.273 |
Leishmania major | phosphoglycerate kinase B, cytosolic | 0.0085 | 0.0972 | 0.273 |
Onchocerca volvulus | 0.0024 | 0.0208 | 0.0728 | |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0208 | 0.2504 | 1 |
Plasmodium vivax | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.273 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0306 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0444 | 0.1773 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0439 | 0.1753 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.001 | 0.0036 | 0.0143 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0306 | 0.0306 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0534 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.1138 | 0.4544 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0306 | 0.1221 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.011 | 0.0439 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.1064 | 0.4248 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.0036 | 0.0036 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.0036 | 0.0143 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.1689 | 0.6746 |
Onchocerca volvulus | 0.001 | 0.0039 | 0.0137 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.0761 | 0.304 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0157 | 0.0157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0156 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.011 | 0.0309 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0482 | 0.1926 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0223 | 0.0892 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.0497 | 0.0497 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0194 | 0.0774 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0361 | 0.0361 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.1689 | 0.6746 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0306 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0391 | 0.156 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0126 | 0.0501 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.1154 | 0.4607 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0292 | 0.3561 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.1677 |
Chlamydia trachomatis | phosphoglycerate kinase | 0.0085 | 0.0972 | 1 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0218 | 0.0613 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0208 | 0.0832 |
Brugia malayi | dihydrofolate reductase family protein | 0.0085 | 0.097 | 0.3873 |
Entamoeba histolytica | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.2739 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.1138 | 0.3207 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0039 | 0.0156 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0036 | 0.0101 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0701 | 0.2797 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.011 | 0.011 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0024 | 0.0218 | 0.0871 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0832 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0039 |
Mycobacterium ulcerans | thymidylate synthase | 0.0208 | 0.2504 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0085 | 0.097 | 0.3873 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0482 | 0.1926 |
Echinococcus granulosus | nibrin | 0.001 | 0.0036 | 0.0143 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.017 | 0.0679 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0482 | 0.0482 |
Trypanosoma brucei | phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0285 | 0.08 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0218 | 0.0613 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0208 | 0.0832 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0024 | 0.0218 | 0.0871 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0039 | 0.0039 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0212 | 0.256 | 0.7188 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0306 | 0.0306 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0039 | 0.0156 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0036 | 0.0101 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.0036 | 0.0101 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.017 | 0.0679 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.2502 | 0.9992 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0361 | 0.1441 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0133 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0534 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.1138 | 0.4544 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0039 | 0.0156 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.011 | 0.0309 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0285 | 0.08 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | Dihydrofolate reductase | 0.0085 | 0.097 | 0.3873 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0439 | 0.1753 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0361 | 0.1441 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.1677 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0085 | 0.097 | 0.3873 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0832 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0126 | 0.0501 |
Brugia malayi | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0832 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0039 | 0.0156 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0208 | 0.0587 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0761 | 0.304 |
Loa Loa (eye worm) | thymidylate synthase | 0.0208 | 0.2504 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0208 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0534 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.1138 | 0.1138 |
Echinococcus multilocularis | phosphoglycerate kinase 1 | 0.0085 | 0.0972 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0513 | 0.0513 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.1154 | 0.4607 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0039 | 0.0156 |
Echinococcus granulosus | thymidylate synthase | 0.0208 | 0.2504 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0361 | 0.1017 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0036 | 0.0101 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.0036 | 0.0101 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0439 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0157 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0972 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0497 | 0.1984 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0761 | 0.304 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0218 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0534 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0218 | 0.0871 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0039 | 0.0156 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0208 | 0.0587 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0482 | 0.1926 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0309 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0085 | 0.097 | 0.9978 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0208 | 0.0832 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0361 | 0.1441 |
Leishmania major | hypothetical protein, conserved | 0.0212 | 0.256 | 0.7188 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0306 | 0.1221 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0208 | 0.2504 | 1 |
Treponema pallidum | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.2664 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0134 | 0.0534 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0036 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0039 | 0.0156 |
Onchocerca volvulus | 0.001 | 0.0036 | 0.0125 | |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.1664 | 0.6643 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0212 | 0.256 | 0.7188 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.011 | 0.0309 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0039 | 0.0156 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.001 | 0.0036 | 0.0143 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0486 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0585 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0439 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0039 | 0.0039 |
Trypanosoma cruzi | 3-phosphoglycerate kinase, glycosomal | 0.0031 | 0.0302 | 0.0848 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.0036 | 0.0143 |
Echinococcus granulosus | phosphoglycerate kinase 1 | 0.0085 | 0.0972 | 0.3881 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0036 | 0.0143 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0557 | 0.2225 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.273 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0085 | 0.097 | 0.3873 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.011 | 0.0309 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0832 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0208 | 0.0832 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0039 | 0.0156 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.011 | 0.0309 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.0036 | 0.0143 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.039 | 0.1557 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0208 | 0.0832 |
Trichomonas vaginalis | set domain proteins, putative | 0.0236 | 0.286 | 0.8058 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0482 | 0.1926 |
Wolbachia endosymbiont of Brugia malayi | phosphoglycerate kinase | 0.0085 | 0.0972 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0486 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0208 | 0.0832 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0039 | 0.0156 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0039 | 0.0156 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.0036 | 0.0101 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0291 | 0.3549 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0439 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1154 | 0.4607 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Leishmania major | phosphoglycerate kinase C, glycosomal | 0.0085 | 0.0972 | 0.273 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.1664 | 0.1664 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0039 | 0.0156 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0486 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0039 | 0.0039 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.2739 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0832 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0039 | 0.0156 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0036 | 0.0101 |
Plasmodium falciparum | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.273 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.273 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0099 | 0.1146 | 0.3218 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0486 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0482 | 0.0482 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0208 | 0.2504 | 1 |
Mycobacterium leprae | Probable phosphoglycerate kinase Pgk | 0.0085 | 0.0972 | 0.3881 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0126 | 0.0501 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0292 | 0.3561 | 1 |
Onchocerca volvulus | 0.0208 | 0.2504 | 0.8757 | |
Echinococcus granulosus | dihydrofolate reductase | 0.0085 | 0.097 | 0.3873 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0039 | 0.0137 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0039 | 0.0156 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0291 | 0.3549 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0439 | 0.1753 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0085 | 0.097 | 0.3873 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0534 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.01 | 0.1157 | 0.462 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0439 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1138 | 0.4544 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0292 | 0.3561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0036 | 0.0101 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0036 | 0.0101 |
Toxoplasma gondii | phosphoglycerate kinase PGKI | 0.0085 | 0.0972 | 0.273 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0846 | 0.338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0482 | 0.1926 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0039 | 0.0156 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.0497 | 0.1984 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Brugia malayi | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0656 | 0.262 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0104 | 0.0291 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.3881 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0306 | 0.1221 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0104 | 0.0291 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0101 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.011 | 0.011 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.011 | 0.0309 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0361 | 0.1441 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.1154 | 0.4607 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0157 | 0.0627 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0085 | 0.0972 | 0.2739 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.0036 | 0.0143 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.011 | 0.0309 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.036 | 0.1439 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.0036 | 0.0101 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.0036 | 0.0143 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0361 | 0.1017 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0285 | 0.0285 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0497 | 0.1984 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.1064 | 0.1064 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.0036 | 0.0143 |
Onchocerca volvulus | 0.003 | 0.0285 | 0.0996 | |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.1677 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.3549 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0306 | 0.0306 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0036 | 0.0101 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0024 | 0.0218 | 0.0871 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0142 | 0.1689 | 0.6746 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0039 | 0.0156 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0208 | 0.0832 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0306 | 0.1221 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0439 | 0.1237 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0024 | 0.0218 | 0.0615 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.001 | 0.0036 | 0.0101 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | thymidylate synthase | 0.0208 | 0.2504 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0361 | 0.1017 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0039 | 0.0137 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0039 | 0.0156 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.036 | 0.036 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0039 | 0.0156 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0031 | 0.0302 | 0.0848 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.011 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0439 | 0.1753 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.2502 | 0.9992 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0156 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | hypothetical protein | 0.0099 | 0.1146 | 0.4576 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0656 | 0.0656 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0039 | 0.0156 |
Brugia malayi | Phosphoglycerate kinase | 0.0085 | 0.0972 | 0.3881 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0036 | 0.0143 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0085 | 0.097 | 0.097 |
Brugia malayi | topoisomerase | 0.001 | 0.0036 | 0.0143 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0285 | 0.1137 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.0832 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0099 | 0.1146 | 0.4576 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.1677 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0292 | 0.3561 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0024 | 0.0218 | 0.0871 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0024 | 0.0218 | 0.0871 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0285 | 0.1137 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0039 | 0.0156 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0497 | 0.1984 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0039 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0039 | 0.0137 |
Mycobacterium ulcerans | phosphoglycerate kinase | 0.0085 | 0.0972 | 0.3881 |
Mycobacterium tuberculosis | Probable phosphoglycerate kinase Pgk | 0.0085 | 0.0972 | 0.3881 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.