Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.015 | 0.168 | 0.168 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.08 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0071 | 0.0671 | 0.0671 |
Schistosoma mansoni | gabp alpha | 0.0071 | 0.0671 | 0.0671 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0071 | 0.0668 | 0.0668 |
Onchocerca volvulus | Bile acid receptor homolog | 0.015 | 0.168 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0428 | 0.5237 | 0.5237 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | nuclear receptor NHR-67 | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | nuclear hormone receptor | 0.0071 | 0.0668 | 0.0668 |
Echinococcus multilocularis | geminin | 0.0166 | 0.1885 | 0.1885 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | nuclear receptor RXR | 0.0079 | 0.0776 | 0.0776 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0079 | 0.0776 | 0.0776 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0079 | 0.0776 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.3978 | 0.3978 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | steroid hormone receptor | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0215 | 0.0215 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.015 | 0.168 | 0.168 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0215 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0368 | 0.0368 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.2723 | 0.2723 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0375 | 0.4566 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.08 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Brugia malayi | CHE-14 protein | 0.0329 | 0.3978 | 0.3978 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0715 | 0.8919 | 0.8919 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0071 | 0.0668 | 0.2286 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1885 | 0.1885 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0329 | 0.3978 | 0.3978 |
Brugia malayi | conserved hypotetical protein | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0071 | 0.0668 | 0.0668 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | nuclear receptor RXR | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0388 | 0.0388 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0215 | 0.0215 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.08 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0715 | 0.8919 | 0.8919 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0329 | 0.3978 | 0.3978 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0715 | 0.8919 | 0.8919 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0071 | 0.0671 | 0.0671 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0329 | 0.3978 | 0.3978 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0329 | 0.3978 | 0.3978 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0191 | 0.0191 |
Brugia malayi | hypothetical protein | 0.0231 | 0.2723 | 0.2723 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0375 | 0.4566 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0388 | 0.0388 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.08 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.0776 | 0.0776 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0109 | 0.1165 | 0.1165 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0071 | 0.0668 | 0.0668 |
Toxoplasma gondii | MAPEG family protein | 0.0109 | 0.1165 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0079 | 0.0776 | 0.0776 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | nuclear hormone receptor | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0071 | 0.0668 | 0.0668 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0337 | 0.0337 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0375 | 0.4566 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | patched 1 | 0.0329 | 0.3978 | 0.3978 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0079 | 0.0776 | 0.0776 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0071 | 0.0668 | 0.2286 |
Brugia malayi | Fli-1 protein | 0.0215 | 0.2515 | 0.2515 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0109 | 0.1165 | 0.1165 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0191 | 0.0191 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0337 | 0.0337 |
Echinococcus granulosus | FTZ F1 alpha | 0.015 | 0.168 | 0.168 |
Brugia malayi | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0073 | 0.0696 | 0.0696 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.0776 | 0.0776 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0071 | 0.0668 | 0.0668 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.2723 | 0.2723 |
Brugia malayi | tailless protein | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.015 | 0.168 | 0.168 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0329 | 0.3978 | 0.3978 |
Onchocerca volvulus | 0.015 | 0.168 | 1 | |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0215 | 0.0215 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.168 | 0.168 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.08 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | coup transcription factor | 0.015 | 0.168 | 0.168 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | fli-1 protein | 0.0215 | 0.2515 | 0.2515 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0539 | 0.0539 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0715 | 0.8919 | 0.8919 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0073 | 0.0696 | 0.0696 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | protein patched | 0.0329 | 0.3978 | 0.3978 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0337 | 0.0337 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0109 | 0.1165 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0191 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0329 | 0.3978 | 0.3978 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0329 | 0.3978 | 0.3978 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0 | 0.5 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0671 | 0.0671 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.015 | 0.168 | 0.168 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0337 | 0.0337 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0375 | 0.4566 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | ecdysone receptor | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.0477 | 0.5874 | 0.5874 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Onchocerca volvulus | 0.0071 | 0.0668 | 0.2286 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0388 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | zinc finger protein | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0368 | 0.0368 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.08 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.015 | 0.168 | 0.168 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0215 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0329 | 0.3978 | 0.8712 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.08 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.168 | 0.168 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | FTZ F1 alpha | 0.015 | 0.168 | 0.168 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.2723 | 0.2723 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0215 | 1 |
Brugia malayi | ecdysteroid receptor | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | ets-related | 0.0215 | 0.2515 | 0.2515 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0079 | 0.0776 | 0.0776 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | nuclear hormone receptor | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | nuclear receptor | 0.0071 | 0.0668 | 0.0668 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.015 | 0.168 | 0.168 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0215 | 0.0215 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.015 | 0.168 | 0.168 |
Onchocerca volvulus | 0.0071 | 0.0668 | 0.2286 | |
Loa Loa (eye worm) | DR-78 | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0337 | 0.0337 |
Brugia malayi | nuclear hormone receptor | 0.015 | 0.168 | 0.168 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0671 | 0.0671 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0071 | 0.0668 | 0.0668 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0071 | 0.0671 | 0.0671 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.015 | 0.168 | 0.168 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0388 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.0668 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0071 | 0.0668 | 0.0668 |
Brugia malayi | hypothetical protein | 0.0079 | 0.0776 | 0.0776 |
Echinococcus multilocularis | protein dispatched 1 | 0.0329 | 0.3978 | 0.3978 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.015 | 0.168 | 0.168 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.08 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.015 | 0.168 | 0.168 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0337 | 0.0337 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0715 | 0.8919 | 0.8919 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.08 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.015 | 0.168 | 0.168 |
Echinococcus granulosus | geminin | 0.0166 | 0.1885 | 0.1885 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.015 | 0.168 | 0.168 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.015 | 0.168 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1885 | 0.1885 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.015 | 0.168 | 0.168 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0215 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.015 | 0.168 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.015 | 0.168 | 0.168 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.015 | 0.168 | 0.168 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.