Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | protein kinase c epsilon type | 0.0742 | 0.1991 | 0.1991 |
Entamoeba histolytica | protein kinase, putative | 0.0355 | 0.0097 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0343 | 0.0037 | 0.0045 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0355 | 0.0097 | 0.0097 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.1636 | 0.6369 | 0.6369 |
Schistosoma mansoni | protein kinase C | 0.0387 | 0.0255 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.1636 | 0.6369 | 0.7419 |
Schistosoma mansoni | protein kinase C mu | 0.0343 | 0.0037 | 0.0037 |
Schistosoma mansoni | unc-13 (munc13) | 0.0387 | 0.0255 | 0.0255 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2378 | 1 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.1696 | 0.6662 | 0.7759 |
Toxoplasma gondii | AGC kinase | 0.0355 | 0.0097 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0355 | 0.0097 | 0.0097 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0343 | 0.0037 | 0.0045 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0355 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0343 | 0.0037 | 0.0044 |
Echinococcus granulosus | protein kinase C gamma type | 0.2043 | 0.836 | 0.836 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0355 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0355 | 0.0097 | 0.0113 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0097 | 0.0097 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0355 | 0.0097 | 0.0097 |
Brugia malayi | Protein kinase domain containing protein | 0.0355 | 0.0097 | 0.0117 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0355 | 0.0097 | 0.5 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.2378 | 1 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0355 | 0.0097 | 0.0113 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0355 | 0.0097 | 0.0097 |
Echinococcus granulosus | NDR protein kinase | 0.0355 | 0.0097 | 0.0097 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.1636 | 0.6369 | 0.6369 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0355 | 0.0097 | 0.0113 |
Schistosoma mansoni | unc-13 (munc13) | 0.0387 | 0.0255 | 0.0255 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0355 | 0.0097 | 0.0113 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0387 | 0.0255 | 0.0255 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0742 | 0.1991 | 0.1991 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0355 | 0.0097 | 0.0113 |
Brugia malayi | C1-like domain containing protein | 0.0343 | 0.0037 | 0.0045 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0355 | 0.0097 | 0.0097 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0097 | 0.0097 |
Schistosoma mansoni | serine/threonine kinase | 0.0355 | 0.0097 | 0.0097 |
Onchocerca volvulus | 0.0387 | 0.0255 | 1 | |
Echinococcus multilocularis | unc 13 (munc13) | 0.0387 | 0.0255 | 0.0255 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0343 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.0097 | 0.0113 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Brugia malayi | protein kinase C II. | 0.0742 | 0.1991 | 0.2399 |
Brugia malayi | Protein kinase domain containing protein | 0.0355 | 0.0097 | 0.0117 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.0255 | 0.0297 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Brugia malayi | protein kinase C3,putative | 0.0343 | 0.0037 | 0.0045 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0343 | 0.0037 | 0.0037 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0355 | 0.0097 | 0.0117 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0355 | 0.0097 | 0.0097 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.1636 | 0.6369 | 0.6369 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0355 | 0.0097 | 0.0097 |
Entamoeba histolytica | protein kinase, putative | 0.0355 | 0.0097 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.069 | 0.1736 | 0.1736 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0355 | 0.0097 | 0.0113 |
Brugia malayi | RasGEF domain containing protein | 0.1752 | 0.6936 | 0.8355 |
Brugia malayi | Protein kinase c protein 2 | 0.2031 | 0.8301 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.2043 | 0.836 | 0.836 |
Loa Loa (eye worm) | hypothetical protein | 0.1971 | 0.8009 | 0.9329 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.2089 | 0.8585 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0355 | 0.0097 | 0.0097 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Echinococcus granulosus | unc 13 munc13 | 0.0387 | 0.0255 | 0.0255 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0387 | 0.0255 | 0.0255 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0343 | 0.0037 | 0.0044 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0343 | 0.0037 | 0.0037 |
Schistosoma mansoni | atypical protein kinase C | 0.069 | 0.1736 | 0.1736 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0742 | 0.1991 | 0.1991 |
Brugia malayi | Protein kinase domain containing protein | 0.0355 | 0.0097 | 0.0117 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0742 | 0.1991 | 0.2319 |
Brugia malayi | Hr1 repeat family protein | 0.0355 | 0.0097 | 0.0117 |
Entamoeba histolytica | protein kinase, putative | 0.0355 | 0.0097 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2378 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0355 | 0.0097 | 1 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0343 | 0.0037 | 0.0037 |
Trichomonas vaginalis | AGC family protein kinase | 0.0355 | 0.0097 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.069 | 0.1736 | 0.1736 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0355 | 0.0097 | 0.0113 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0355 | 0.0097 | 0.0097 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.