Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1509 | 0.2486 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1509 | 0.2486 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2517 | 0.1187 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.2517 | 0.2445 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0096 | 0.0381 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.2517 | 0.1187 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.2517 | 0.5 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0096 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2517 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.2517 | 1 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.2517 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.2517 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2517 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1509 | 0.2486 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.2517 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.607 | 0.6032 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.2517 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.607 | 0.5371 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.1509 | 0.1427 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.2517 | 0.4147 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.2517 | 0.5 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0096 | 0.5 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.2517 | 0.4147 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.1509 | 0.2486 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0096 | 0.0381 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.2517 | 0.5 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.2517 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.2517 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.1509 | 0.1427 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.2517 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0096 | 0.0158 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.2517 | 0.2445 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.607 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0096 | 0.0000000020559 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.2517 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 1 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.2517 | 0.5 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.2517 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2517 | 0.1187 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.2517 | 0.2445 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.2517 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.2517 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.