Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0895 | 0.4467 | 1 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0785 | 0.3868 | 0.3868 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0785 | 0.3868 | 0.3868 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1907 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0785 | 0.3868 | 0.866 |
Loa Loa (eye worm) | hypothetical protein | 0.0785 | 0.3868 | 0.3868 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.1907 | 1 | 1 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0895 | 0.4467 | 1 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0895 | 0.4467 | 1 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1907 | 1 | 0.5 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.1907 | 1 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0785 | 0.3868 | 0.3868 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.1907 | 1 | 0.5 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0785 | 0.3868 | 0.3868 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0895 | 0.4467 | 1 |
Echinococcus multilocularis | protein patched | 0.0785 | 0.3868 | 0.3868 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0785 | 0.3868 | 0.3868 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.1907 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1907 | 1 | 1 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1907 | 1 | 0.5 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0785 | 0.3868 | 0.3868 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0785 | 0.3868 | 0.3868 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1907 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.