Detailed information for compound 829726

Basic information

Technical information
  • TDR Targets ID: 829726
  • Name: 2-[3-(4-methoxyphenyl)-5-methyl-7-oxopyrano[5 ,6-f][1]benzoxol-6-yl]acetic acid
  • MW: 364.348 | Formula: C21H16O6
  • H donors: 1 H acceptors: 3 LogP: 3.3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1coc2c1cc1c(c2)oc(=O)c(c1C)CC(=O)O
  • InChi: 1S/C21H16O6/c1-11-14-7-16-17(12-3-5-13(25-2)6-4-12)10-26-18(16)9-19(14)27-21(24)15(11)8-20(22)23/h3-7,9-10H,8H2,1-2H3,(H,22,23)
  • InChiKey: YKCRRDVZXWZRLJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[3-(4-methoxyphenyl)-5-methyl-7-oxo-pyrano[5,6-f]benzofuran-6-yl]acetic acid
  • 2-[3-(4-methoxyphenyl)-5-methyl-7-oxo-6-pyrano[5,6-f]benzofuranyl]acetic acid
  • 2-[7-keto-3-(4-methoxyphenyl)-5-methyl-pyrano[5,6-f]benzofuran-6-yl]acetic acid
  • 2-[3-(4-methoxyphenyl)-5-methyl-7-oxo-pyrano[5,6-f][1]benzoxol-6-yl]ethanoic acid
  • ChemDiv3_014499
  • IDI1_030297
  • STOCK1N-35474

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0223 0.0143
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0037 0.0082 0.0135
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0187 0.6066 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0037 0.0082 0.0048
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0037 0.0082 0.0048
Brugia malayi proteasome subunit alpha type 2 0.0037 0.0082 0.0034
Loa Loa (eye worm) PAS-3 protein 0.0037 0.0082 0.0034
Echinococcus granulosus proteasome subunit alpha type 2 0.0037 0.0082 0.0135
Plasmodium vivax proteasome subunit beta type-4, putative 0.0037 0.0082 0.0048
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0186 0.0173
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.009 0.2204 0.3546
Plasmodium vivax proteasome subunit beta type-6, putative 0.0037 0.0082 0.0048
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0145 0.4405 0.7261
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0037 0.0082 0.0048
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0037 0.0082 0.0048
Echinococcus multilocularis proteasome subunit alpha type 2 0.0037 0.0082 0.0048
Echinococcus multilocularis proteasome subunit beta type 6 0.0037 0.0082 0.0048
Plasmodium falciparum proteasome subunit beta type-5 0.0187 0.6066 1
Echinococcus multilocularis proteasome (prosome, macropain) 0.0187 0.6066 1
Brugia malayi Proteasome subunit alpha type 7-1 0.0037 0.0082 0.0034
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0187 0.6066 1
Giardia lamblia Proteasome subunit beta type 2 0.009 0.2204 0.3546
Brugia malayi proteasome subunit beta type 3 0.0037 0.0082 0.0034
Brugia malayi Proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0187 0.6066 1
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0037 0.0082 0.0034
Trypanosoma cruzi 20S proteasome subunit 0.009 0.2204 0.3546
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0145 0.4405 0.7224
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0223 0.0199
Echinococcus granulosus proteasome subunit beta t family 0.0037 0.0082 0.0135
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0037 0.0082 0.0048
Echinococcus granulosus subfamily T1A non peptidase ue 0.0037 0.0082 0.0135
Trypanosoma brucei proteasome beta 6 subunit 0.0145 0.4405 0.7224
Echinococcus granulosus Proteasome subunit alpha type 7 0.0037 0.0082 0.0135
Trichomonas vaginalis set domain proteins, putative 0.0286 1 1
Brugia malayi proteasome subunit alpha type 1 0.0037 0.0082 0.0034
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0037 0.0082 0.0135
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0037 0.0082 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.8618 1
Brugia malayi proteasome subunit alpha type 3 0.0037 0.0082 0.0034
Trichomonas vaginalis rotamase, putative 0.004 0.0223 0.0143
Echinococcus granulosus proteasome subunit beta type 7 0.0037 0.0082 0.0135
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0037 0.0082 0.0048
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0186 0.0221
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0037 0.0082 0.0034
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0037 0.0082 0.0048
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0187 0.6066 1
Plasmodium vivax proteasome subunit beta type-5, putative 0.0187 0.6066 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.2204 0.3577
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Leishmania major proteasome beta 5 subunit, putative 0.0187 0.6066 1
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0037 0.0082 0.0048
Echinococcus multilocularis expressed protein 0.004 0.0223 0.0284
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0037 0.0082 0.0048
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0037 0.0082 0.0048
Echinococcus granulosus expressed protein 0.004 0.0223 0.0368
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0037 0.0082 0.0048
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.4405 0.7224
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0145 0.4405 0.7237
Brugia malayi Proteasome A-type and B-type family protein 0.0187 0.6066 0.702
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0037 0.0082 0.0048
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0037 0.0082 0.0048
Loa Loa (eye worm) proteasome subunit beta type 2 0.009 0.2204 0.2511
Loa Loa (eye worm) proteasome subunit beta type 1 0.0145 0.4405 0.5081
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0037 0.0082 0.0034
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0037 0.0082 0.0048
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0186 0.0173
Brugia malayi Pre-SET motif family protein 0.0251 0.8618 1
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0037 0.0082 0.0048
Toxoplasma gondii proteasome subunit alpha type, putative 0.0037 0.0082 0.0048
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0037 0.0082 0.5
Toxoplasma gondii heat shock protein hslv, putative 0.0037 0.0082 0.0048
Plasmodium vivax proteasome subunit beta type-3, putative 0.0037 0.0082 0.0048
Echinococcus granulosus proteasome subunit alpha type 6 0.0037 0.0082 0.0135
Mycobacterium ulcerans proteasome PrcB 0.0187 0.6066 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0187 0.6066 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0037 0.0082 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0053 0.0087
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0187 0.6066 1
Onchocerca volvulus Notchless protein homolog 0.0037 0.0082 0.0029
Echinococcus granulosus Proteasome subunit alpha beta 0.0037 0.0082 0.0135
Echinococcus multilocularis proteasome subunit beta type 7 0.0037 0.0082 0.0048
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.4405 0.7224
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0145 0.4405 0.4359
Brugia malayi proteasome subunit alpha type 4 0.0037 0.0082 0.0034
Leishmania major proteasome beta 2 subunit, putative 0.009 0.2204 0.3546
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0037 0.0082 0.0034
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0037 0.0082 0.0048
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0186 0.0173
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0223 0.0199
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0037 0.0082 0.0048
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0037 0.0082 0.0048
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0145 0.4405 0.7224
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0187 0.6066 1
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0037 0.0082 0.0048
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0037 0.0082 0.0048
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.2204 0.2139
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.2204 0.3577
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0037 0.0082 0.0048
Brugia malayi 20S proteasome alpha5 subunit 0.0037 0.0082 0.0034
Plasmodium vivax proteasome subunit beta type-1, putative 0.0145 0.4405 0.7237
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0037 0.0082 0.0048
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0186 0.0173
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0037 0.0082 0.0048
Loa Loa (eye worm) proteasome subunit beta type 3 0.0037 0.0082 0.0034
Toxoplasma gondii proteasome subunit beta type 2, putative 0.009 0.2204 0.3577
Brugia malayi Proteasome subunit alpha type 1 0.0037 0.0082 0.0034
Brugia malayi proteasome subunit beta type 2 0.009 0.2204 0.2511
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0037 0.0082 0.0034
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0037 0.0082 0.0048
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.009 0.2204 0.3546
Toxoplasma gondii proteasome subunit alpha1, putative 0.0037 0.0082 0.0048
Trichomonas vaginalis rotamase, putative 0.0039 0.0186 0.0104
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0037 0.0082 0.0048
Brugia malayi proteasome subunit beta type 1 0.0145 0.4405 0.5081
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0037 0.0082 0.0048
Toxoplasma gondii proteasome subunit 0.0037 0.0082 0.0048
Plasmodium vivax proteasome subunit beta type-2, putative 0.009 0.2204 0.3577
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0037 0.0082 0.0048
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0187 0.6066 1
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0037 0.0082 0.0048
Toxoplasma gondii proteasome subunit beta type, putative 0.0187 0.6066 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0037 0.0082 0.0048
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0037 0.0082 0.0048
Echinococcus granulosus proteasome subunit beta type 6 0.0037 0.0082 0.0135
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0037 0.0082 0.0048
Toxoplasma gondii proteasome beta subunit 0.0037 0.0082 0.0048
Plasmodium falciparum proteasome subunit beta type-2, putative 0.009 0.2204 0.3546
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0037 0.0082 0.0048
Brugia malayi proteasome subunit alpha type 6 0.0037 0.0082 0.0034
Trypanosoma brucei proteasome subunit beta type-2, putative 0.009 0.2204 0.3546
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.009 0.2204 0.3577
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0037 0.0082 0.0135
Schistosoma mansoni rotamase 0.004 0.0223 0.0284
Echinococcus multilocularis proteasome subunit alpha type 6 0.0037 0.0082 0.0048
Toxoplasma gondii peptidase, T1 family protein 0.0037 0.0082 0.0048
Echinococcus granulosus proteasome prosome macropain 0.0187 0.6066 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0187 0.6066 0.702
Brugia malayi Proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0145 0.4405 0.7237
Plasmodium vivax proteasome subunit beta type-7, putative 0.0037 0.0082 0.0048
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.2204 0.2139
Echinococcus granulosus proteasome prosome macropain subunit beta 0.009 0.2204 0.3633
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0037 0.0082 0.0048
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0037 0.0082 0.0048
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0187 0.6066 0.6034
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0145 0.4405 0.7224
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0037 0.0082 0.0034
Brugia malayi Proteasome A-type and B-type family protein 0.0037 0.0082 0.0034
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0145 0.4405 0.7237
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0186 0.0173
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0037 0.0082 0.0048
Giardia lamblia Proteasome subunit beta type 1 0.0145 0.4405 0.7224

Activities

Activity type Activity value Assay description Source Reference
AbsAC40_uM (functional) > 26 uM PUBCHEM_BIOASSAY: Sustained Induction of HSF-1 Measured in Cell-Based System Using Plate Reader - 2038-07_Activator_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
EC50 (functional) > 260 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493224] ChEMBL. No reference
Potency (functional) 1.4125 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 21.3349 uM PubChem BioAssay. qHTS for Inhibitors of the Phosphatase Activity of Eya2: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8545 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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