Detailed information for compound 83017

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 380.828 | Formula: C20H17ClN4O2
  • H donors: 1 H acceptors: 3 LogP: 3.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc2c(c1)CCN2C(=O)Nc1ccc(nc1)OCc1ccccn1
  • InChi: 1S/C20H17ClN4O2/c21-15-4-6-18-14(11-15)8-10-25(18)20(26)24-16-5-7-19(23-12-16)27-13-17-3-1-2-9-22-17/h1-7,9,11-12H,8,10,13H2,(H,24,26)
  • InChiKey: ODLQXWMYQDSIKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Echinococcus granulosus hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.021 0.021
Schistosoma mansoni zinc finger protein 0.0015 0.0093 0.0097
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0251 0.2864 0.3744
Leishmania major cathepsin L-like protease 0.0019 0.0138 0.0541
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0081 0.0143
Schistosoma mansoni cpg binding protein 0.0034 0.0311 0.0323
Trypanosoma brucei trypanothione reductase 0.0031 0.0278 0.109
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0336 0.0499
Brugia malayi tailless protein 0.0017 0.0114 0.0169
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Schistosoma mansoni zinc finger protein 0.0028 0.0246 0.0256
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0584 0.0584
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0025 0.021 0.0311
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.021 0.0218
Echinococcus multilocularis thioredoxin glutathione reductase 0.0031 0.0283 0.0291
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0271 0.2866
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0006 0.0006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Brugia malayi nuclear receptor NHR-88 0.0036 0.0336 0.0499
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0061 0.0637 0.0832
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0114 0.0169
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0711 0.0711
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0203 0.0265
Schistosoma mansoni hypothetical protein 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0162
Onchocerca volvulus 0.0025 0.021 0.0797
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.0014 0.0018
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0068 0.0071
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0012 0.0062 0.0656
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0027 0.0105
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1231 1
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0009 0.0027 0.0105
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1231 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0265 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.021 0.021
Schistosoma mansoni bromodomain containing protein 0.0009 0.0027 0.0028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Toxoplasma gondii hypothetical protein 0.0009 0.0027 0.0283
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Echinococcus granulosus dnaJ subfamily B 0.0825 0.9614 0.9614
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Echinococcus granulosus sex peptide receptor 0.0025 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.002 0.0154 0.0273
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0088 0.0946 0.1237
Entamoeba histolytica hypothetical protein 0.0019 0.0135 0.1095
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.021 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0293 0.3354 0.3488
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0114 0.0114
Echinococcus multilocularis CREB binding protein 0.0009 0.0027 0.0028
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0243
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Trypanosoma cruzi cruzipain precursor, putative 0.0019 0.0138 0.0541
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0006 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0114 0.0169
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0138 0.0205
Onchocerca volvulus 0.0025 0.021 0.0797
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0011 0.0041 0.0054
Echinococcus granulosus CREB binding protein 0.0009 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Echinococcus multilocularis serotonin receptor 0.0135 0.1497 0.1542
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0041 0.0436
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0009 0.0018 0.0071
Echinococcus granulosus histone acetyltransferase KAT2B 0.0088 0.0946 0.0946
Echinococcus multilocularis fmrfamide receptor 0.0025 0.021 0.0216
Schistosoma mansoni lamin 0.0026 0.0224 0.0233
Brugia malayi hypothetical protein 0.0017 0.0114 0.0169
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Echinococcus granulosus tachykinin peptides receptor 99D 0.0025 0.021 0.021
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0025 0.021 0.0216
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0336 0.0336
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Schistosoma mansoni nocturnin 0.0008 0.0006 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1231 0.468
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Trichomonas vaginalis bromodomain-containing protein, putative 0.0088 0.0946 0.3596
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Schistosoma mansoni biogenic amine receptor 0.0025 0.021 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma cruzi Bromodomain factor 1 0.0009 0.0027 0.0105
Echinococcus multilocularis PH interacting protein 0.0009 0.0027 0.0028
Echinococcus granulosus dro:myosuppressin receptor 0.0025 0.021 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.0008 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0154 0.0154
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0571 0.0747
Echinococcus multilocularis bromodomain containing protein 8 0.0009 0.0027 0.0028
Leishmania major hypothetical protein, conserved 0.0015 0.0093 0.0365
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0008 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Echinococcus granulosus histone acetyltransferase KAT2B 0.0282 0.3231 0.3231
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0011 0.0041 0.0054
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0135 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0081 0.012
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0027 0.0283
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0118 0.0155
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Brugia malayi CXXC zinc finger family protein 0.003 0.0268 0.0399
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0336 0.0594
Leishmania major pantothenate kinase subunit, putative 0.0009 0.0018 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0336 0.0594
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0203 0.1646
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0016 0.0017
Schistosoma mansoni ap endonuclease 0.0038 0.0365 0.0379
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1231 0.468
Echinococcus multilocularis protein kinase C binding protein 1 0.0009 0.0027 0.0028
Brugia malayi Dopamine receptor 0.0025 0.021 0.0311
Brugia malayi 6-phosphofructokinase 0.0112 0.1232 0.1828
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0658 0.7651 1
Echinococcus granulosus neuropeptide receptor A26 0.0025 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0113 0.0117
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0006 0.0008
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0365 0.1431
Echinococcus multilocularis global transcription activator snf2l2 0.0009 0.0027 0.0028
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0365 0.1386
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Brugia malayi hypothetical protein 0.0019 0.0135 0.02
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.092 0.7475
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0016 0.0016
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0025 0.021 0.037
Echinococcus granulosus fmrfamide receptor 0.0025 0.021 0.021
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.1231 0.1268
Trypanosoma brucei Bromodomain, putative 0.0009 0.0027 0.0105
Trichomonas vaginalis DNA-directed RNA polymerase III subunit, putative 0.0013 0.0068 0.0258
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0027 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0336 0.0594
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0006 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0203 0.0265
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0336 0.0499
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Loa Loa (eye worm) hypothetical protein 0.002 0.0154 0.0273
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0006 0.0052
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0017 0.0114 0.0118
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0006 0.0008
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Schistosoma mansoni alpha-1 adrenergic receptor 0.0025 0.021 0.0218
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Trypanosoma brucei calpain-like protein, putative 0.0224 0.2549 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Echinococcus multilocularis musashi 0.0026 0.0224 0.0231
Echinococcus multilocularis neuropeptide receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) phosphofructokinase 0.0112 0.1231 0.2174
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0009 0.0027 0.0035
Echinococcus granulosus bromodomain containing 2 0.0009 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.021 0.0218
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0336 0.035
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0365 0.1431
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Schistosoma mansoni lipoxygenase 0.0057 0.0584 0.0607
Echinococcus multilocularis g protein coupled receptor 0.0025 0.021 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0011 0.0041 0.0144
Onchocerca volvulus 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0135 0.1497 0.2642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Brugia malayi PHD-finger family protein 0.0033 0.0308 0.0457
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0009 0.0027 0.0027
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0658 0.7651 1
Onchocerca volvulus 0.0025 0.021 0.0797
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0009 0.0027 0.0028
Brugia malayi hypothetical protein 0.0019 0.0138 0.0205
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0027 0.0105
Schistosoma mansoni microtubule-associated protein tau 0.0367 0.4232 0.4402
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0203 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0011 0.0041 0.0054
Echinococcus multilocularis RUN 0.002 0.0154 0.0159
Trypanosoma brucei Bromodomain, putative 0.0009 0.0027 0.0105
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.001 0.0039 0.0148
Plasmodium falciparum glutathione reductase 0.0031 0.0278 0.0363
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.1231 0.483
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Schistosoma mansoni loxhd1 0.002 0.0154 0.0161
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0025 0.021 0.0311
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0135 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1231 0.468
Brugia malayi nuclear receptor NHR-67 0.0017 0.0114 0.0169
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Plasmodium falciparum bromodomain protein 2, putative 0.0009 0.0027 0.0035
Echinococcus granulosus thioredoxin glutathione reductase 0.0031 0.0283 0.0283
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0025 0.021 0.0218
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0203 0.0795
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0008 0.0006 0.0025
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0571 0.0571
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0138 0.0138
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0135 0.0238
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0676 0.0704
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0024
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0027 0.0283
Echinococcus multilocularis nuclear receptor nhr 48 0.0017 0.0114 0.0118
Giardia lamblia Hypothetical protein 0.0008 0.0014 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Brugia malayi Pre-SET motif family protein 0.0203 0.2302 0.3417
Brugia malayi PXA domain containing protein 0.0019 0.0135 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Schistosoma mansoni hypothetical protein 0.0009 0.0027 0.0028
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Schistosoma mansoni opsin-like receptor 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Toxoplasma gondii DNA-directed RNA polymerase I RPA2 0.0009 0.0025 0.0263
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Brugia malayi hypothetical protein 0.0118 0.1307 0.194
Schistosoma mansoni hypothetical protein 0.0009 0.0027 0.0028
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Leishmania major phosphopantetheinyl transferase-like protein 0.0012 0.0062 0.0243
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0018 0.013 0.023
Echinococcus granulosus G protein coupled receptor 139 0.0025 0.021 0.021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0138 0.0142
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0011 0.0041 0.0054
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0012 0.0062 0.0081
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0203 0.0795
Brugia malayi nuclear hormone receptor 0.0017 0.0114 0.0169
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0012 0.0062 0.0081
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.021 0.0218
Onchocerca volvulus 0.0024 0.0203 0.077
Schistosoma mansoni bromodomain containing protein 0.0013 0.0069 0.0072
Plasmodium falciparum DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0068 0.0089
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0006 0.0006
Leishmania major DNA-directed RNA polymerase polypeptide, putative 0.0013 0.0068 0.0266
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.021 0.021
Onchocerca volvulus 0.0009 0.0027 0.0102
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.0114 0.0434
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0135 0.0135
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0025 0.021 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0243
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0118 0.0155
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Mycobacterium ulcerans hydrolase 0.0008 0.0014 0.0018
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0135 0.0135
Brugia malayi acetyltransferase, GNAT family protein 0.0293 0.3354 0.4978
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.021 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Schistosoma mansoni biogenic amine receptor 0.0025 0.021 0.0218
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.021 0.021
Echinococcus multilocularis sex peptide receptor 0.0025 0.021 0.0216
Plasmodium falciparum DNA-directed RNA polymerase I subunit RPA2, putative 0.0009 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0036 0.0336 0.0336
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.1231 0.1609
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0135 0.02
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0126 0.1399 0.1441
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0025 0.021 0.0218
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0224 0.2549 1
Schistosoma mansoni DNA-directed rna polymerase II subunit 0.0013 0.0068 0.0071
Echinococcus multilocularis peregrin 0.0009 0.0027 0.0028
Schistosoma mansoni synaptojanin 0.0008 0.0006 0.0007
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.021 0.0218
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0135 0.02
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0068 0.0551
Echinococcus granulosus microtubule associated protein 2 0.0367 0.4232 0.4232
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi hypothetical protein 0.002 0.0154 0.0229
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0025 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0336 0.035
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Onchocerca volvulus 0.0025 0.021 0.0797
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0006 0.0024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0041 0.0162
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.013 0.017
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0336 0.0594
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0068 0.0258
Schistosoma mansoni bromodomain containing protein 0.0071 0.0753 0.0783
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus multilocularis 0.0009 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0047 0.0462 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Echinococcus granulosus thyroid hormone receptor alpha 0.0017 0.0114 0.0114
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0203 0.0265
Toxoplasma gondii thioredoxin reductase 0.0031 0.0278 0.2938
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0025 0.021 0.0218
Giardia lamblia Hypothetical protein 0.0009 0.0027 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0336 0.0499
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0006 0.0011
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0114 0.0114
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0006 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0118 0.0155
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0336 0.0499
Echinococcus granulosus synaptojanin 1 0.0008 0.0006 0.0006
Plasmodium vivax DNA-directed RNA polymerase I subunit RPA2, putative 0.0009 0.0025 0.0033
Plasmodium vivax thioredoxin reductase, putative 0.0031 0.0278 0.0363
Onchocerca volvulus Putative neutral sphingomyelinase 0.0008 0.0006 0.0024
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0224 0.0332
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0135 0.0135
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.0114 0.0119
Echinococcus granulosus global transcription activator snf2l2 0.0009 0.0027 0.0027
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0006 0.0008
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0025 0.021 0.0216
Echinococcus multilocularis somatostatin receptor 0.0025 0.021 0.0216
Brugia malayi Tachykinin-like peptides receptor 99D 0.0025 0.021 0.0311
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1231 1
Schistosoma mansoni amine GPCR 0.0025 0.021 0.0218
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0218 0.0385
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0006 0.0024
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0571 0.0594
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.036 0.0636
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0336 0.0499
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0336 0.035
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0135 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0027 0.0283
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0027 0.0105
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Onchocerca volvulus 0.002 0.0154 0.0587
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0251 0.2864 1
Plasmodium falciparum bromodomain protein, putative 0.0009 0.0027 0.0035
Onchocerca volvulus 0.0044 0.0436 0.1657
Plasmodium vivax DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0068 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0336 0.0336
Brugia malayi ORL1-like opioid receptor 0.0025 0.021 0.0311
Loa Loa (eye worm) BRM protein 0.0009 0.0027 0.0047
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0162
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0006 0.0007
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0268 0.0474
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis bromodomain containing 2 0.0009 0.0027 0.0028
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0711 0.0733
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0088 0.0946 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0006 0.0052
Brugia malayi putative neuropeptide receptor 0.0025 0.021 0.0311
Echinococcus granulosus nuclear receptor nhr 48 0.0017 0.0114 0.0114
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0114 0.0118
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0041 0.0157
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0011 0.0041 0.0054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0365 0.1431
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Onchocerca volvulus UPF0528 protein homolog 0.004 0.0382 0.1453
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0025 0.021 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0135 0.014
Schistosoma mansoni neuropeptide receptor 0.0025 0.021 0.0218
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0135 0.014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.2549 1
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0278 0.109
Brugia malayi NC domain containing protein 0.004 0.0382 0.0567
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0011
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0065 0.0066
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0025 0.021 0.021
Leishmania major hypothetical protein, conserved 0.0008 0.0006 0.0025
Echinococcus granulosus peptide allatostatin:somatostatin 0.0025 0.021 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma brucei AAA ATPase, putative 0.0009 0.0027 0.0105
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.021 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0135 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0006 0.0025
Schistosoma mansoni hypothetical protein 0.0009 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis dnaJ subfamily B 0.0825 0.9614 0.9905
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0008 0.0006 0.0007
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0025 0.021 0.0218
Echinococcus multilocularis g-protein coupled receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0135 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0114 0.0169
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0025 0.021 0.0216
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.0008 0.0012
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0041 0.0436
Schistosoma mansoni transcription initiation factor tfiid 0.0009 0.0027 0.0028
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0135 0.014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0271 0.0926
Brugia malayi BRM protein 0.0009 0.0027 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0365 0.0477
Echinococcus multilocularis G-protein coupled receptor, putative 0.0025 0.021 0.0216
Brugia malayi putative neuropeptide receptor NPR1 0.0025 0.021 0.0311
Giardia lamblia Transcription regulatory protein SNF2 0.0009 0.0027 0.0246
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0154 0.0202
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0008 0.0006 0.0025
Echinococcus granulosus 7tm_1 domain containing protein 0.0025 0.021 0.021
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0025 0.021 0.037
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0138 0.0243
Plasmodium vivax SET domain containing protein 0.0011 0.0047 0.0061
Mycobacterium ulcerans arylsulfatase AtsB 0.0008 0.0014 0.0018
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0011 0.0041 0.0054
Brugia malayi TAZ zinc finger family protein 0.0009 0.0027 0.004
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0008 0.0006 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.021 0.0216
Onchocerca volvulus 0.0025 0.021 0.0797
Schistosoma mansoni thyroid hormone receptor 0.0162 0.182 0.1893
Trypanosoma cruzi bromodomain factor 2 protein 0.0009 0.0027 0.0105
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.0114 0.0119
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0154 0.0154
Brugia malayi steroid hormone receptor 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0041
Toxoplasma gondii DNA-directed RNA polymerase II RPB2 0.0013 0.0068 0.0717
Schistosoma mansoni neuropeptide receptor 0.0025 0.021 0.0218
Echinococcus granulosus cpg binding protein 0.0034 0.0311 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma cruzi DNA-directed RNA polymerase II subunit 2, putative 0.0009 0.0016 0.0064
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0024
Schistosoma mansoni opsin-like receptor 0.0025 0.021 0.0218
Onchocerca volvulus 0.0011 0.0044 0.0168
Onchocerca volvulus 0.0008 0.0006 0.0024
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0114 0.0169
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0006 0.0024
Plasmodium vivax SET domain protein, putative 0.003 0.0265 0.0346
Echinococcus granulosus serotonin receptor 0.0025 0.021 0.021
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0336 0.0346
Schistosoma mansoni rab6-interacting 0.002 0.0154 0.0161
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0008 0.0014 0.0053
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0336 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0008 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0336 0.1278
Entamoeba histolytica hypothetical protein 0.0012 0.0062 0.0504
Brugia malayi PXA domain containing protein 0.0019 0.0135 0.02
Echinococcus granulosus zinc finger protein 0.0028 0.0246 0.0246
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0006 0.0024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0011 0.0041 0.0054
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0008 0.0006 0.0006
Schistosoma mansoni bromodomain containing 0.0009 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0358
Loa Loa (eye worm) RNA polymerase III 128kD subunit-PA 0.0013 0.0068 0.012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Giardia lamblia Hypothetical protein 0.0009 0.0027 0.0246
Leishmania major hypothetical protein, conserved 0.0009 0.0027 0.0105
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0462 0.0476
Echinococcus granulosus alpha 1A adrenergic receptor 0.0025 0.021 0.021
Onchocerca volvulus 0.0025 0.021 0.0797
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0224 0.0395
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0336 0.0594
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0062 0.0243
Schistosoma mansoni amine GPCR 0.0025 0.021 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0224 0.2549 1
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0658 0.7651 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0203 0.0265
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0006 0.0052
Onchocerca volvulus 0.0017 0.0114 0.0434
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0265 0.2797
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0006 0.0011
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0135 0.0139
Echinococcus multilocularis neuropeptide FF receptor 2 0.0025 0.021 0.0216
Echinococcus granulosus RUN 0.002 0.0154 0.0154
Giardia lamblia Kinase, putative 0.0009 0.0027 0.0246
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0203 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0135 0.02
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0162 0.182 0.1893
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Schistosoma mansoni hypothetical protein 0.0025 0.021 0.0218
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0025 0.021 0.0797
Schistosoma mansoni neuropeptide receptor 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0293 0.3354 0.3455
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0336 0.035
Leishmania major hypothetical protein, conserved 0.0008 0.0006 0.0025
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0135 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0336 0.0594
Loa Loa (eye worm) DNA-directed RNA polymerase 0.0011 0.0041 0.0072
Echinococcus multilocularis neuropeptide receptor A26 0.0025 0.021 0.0216
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0365 0.1431
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0135 0.02
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Brugia malayi Melatonin receptor type 1A 0.0025 0.021 0.0311
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0006 0.0011
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0008 0.0006 0.0025
Brugia malayi DNA-directed RNA polymerase II second largest subunit, putative 0.0013 0.0068 0.0101
Plasmodium vivax DNA-directed RNA polymerase III subunit, putative 0.0013 0.0068 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0114 0.0118
Loa Loa (eye worm) hypothetical protein 0.0044 0.0436 0.0769
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.092 0.7475
Trypanosoma cruzi RNA polymerase I second largest subunit, putative 0.0009 0.0025 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0041 0.0162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Echinococcus granulosus neuropeptide receptor 0.0025 0.021 0.021
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0009 0.0025 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Trypanosoma brucei Bromodomain, putative 0.0009 0.0027 0.0105
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0027 0.0283
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0025 0.021 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0041 0.0157
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0006 0.0025
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.1231 0.1281
Brugia malayi DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide 0.0013 0.0068 0.0101
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0336 0.0346
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0224 0.2549 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0065 0.0114
Entamoeba histolytica ankyrin repeat protein, putative 0.0009 0.0027 0.0217
Echinococcus granulosus CREB binding protein 0.0009 0.0027 0.0027
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0271 0.2202
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0058 0.0086
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.021 0.037
Brugia malayi G-protein coupled receptor 0.0025 0.021 0.0311
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.021 0.0216
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0658 0.7651 1
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.0014 0.0018
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0135 0.02
Onchocerca volvulus 0.0009 0.0027 0.0102
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0365 0.0477
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0006 0.0024
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.021 0.021
Onchocerca volvulus 0.0026 0.0224 0.0851
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0336 0.0499
Onchocerca volvulus 0.0036 0.0336 0.1278
Brugia malayi G protein-coupled receptor 0.0025 0.021 0.0311
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0006 0.0007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.0114 0.0434
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0012 0.0062 0.0081
Brugia malayi neuropeptide F receptor 0.0025 0.021 0.0311
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0044 0.0436 0.0647
Echinococcus granulosus orexin receptor type 2 0.0025 0.021 0.021
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Echinococcus granulosus PH interacting protein 0.0009 0.0027 0.0027
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0154 0.0154
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0203 0.0301
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Giardia lamblia Histone acetyltransferase GCN5 0.0078 0.0835 1
Echinococcus granulosus intermediate filament protein 0.0026 0.0224 0.0224
Schistosoma mansoni nuclear receptor 0.0017 0.0114 0.0119
Mycobacterium ulcerans hypothetical protein 0.0024 0.0203 0.0265
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0006 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0204 0.036
Giardia lamblia Hypothetical protein 0.0008 0.0014 0.009
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0135 0.0135
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0006 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.021 0.0218
Treponema pallidum NADH oxidase 0.0011 0.0041 0.0122
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0203 0.1646
Trypanosoma cruzi DNA-directed RNA polymerase III, putative 0.0013 0.0068 0.0266
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.1497 0.1557
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0336 0.0594
Leishmania major hypothetical protein, conserved 0.0008 0.0006 0.0025
Onchocerca volvulus 0.0008 0.0006 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0016
Loa Loa (eye worm) DNA-directed RNA polymerase II second largest subunit 0.0013 0.0068 0.012
Echinococcus granulosus polybromo 1 0.0009 0.0027 0.0027
Entamoeba histolytica DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide, putative 0.0013 0.0068 0.0551
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0027 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0336 0.0336
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0026 0.0224 0.0395
Schistosoma mansoni cpg binding protein 0.0034 0.0311 0.0323
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0114 0.0119
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0012 0.0062 0.0081
Schistosoma mansoni intermediate filament proteins 0.0026 0.0224 0.0233
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0006 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0138 0.0541
Loa Loa (eye worm) hypothetical protein 0.007 0.0735 0.1298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0571 0.2242
Loa Loa (eye worm) hypothetical protein 0.0013 0.0069 0.0122
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Echinococcus multilocularis L aminoadipate semialdehyde 0.0044 0.0436 0.0449
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0135 0.0139
Brugia malayi intermediate filament protein 0.0026 0.0224 0.0332
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0025 0.021 0.0311
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0135 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0194 0.0342
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0113 0.0113
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Plasmodium falciparum thioredoxin reductase 0.0031 0.0278 0.0363
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0027 0.0102
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0336 0.0336
Echinococcus multilocularis conserved hypothetical protein 0.0833 0.9706 1
Onchocerca volvulus 0.0025 0.021 0.0797
Echinococcus multilocularis cpg binding protein 0.0034 0.0311 0.032
Echinococcus granulosus neuropeptide receptor 0.0025 0.021 0.021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0336 0.0499
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0251 0.2864 0.371
Loa Loa (eye worm) TYRA-2 protein 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) CBP-B 0.0009 0.0027 0.0047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0224 0.2549 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0025 0.021 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0135 0.014
Onchocerca volvulus 0.0025 0.021 0.0797
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0009 0.0027 0.0028
Echinococcus granulosus protein kinase C binding protein 1 0.0009 0.0027 0.0027
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0006 0.0007
Brugia malayi phosphofructokinase 0.0112 0.1231 0.1827
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0025 0.021 0.0218
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0138 0.0205
Brugia malayi Bromodomain containing protein 0.0045 0.0443 0.0658
Schistosoma mansoni hypothetical protein 0.002 0.0155 0.0161
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0025 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Mycobacterium leprae conserved hypothetical protein 0.0012 0.0062 0.0217
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Loa Loa (eye worm) hypothetical protein 0.0051 0.0514 0.0907
Echinococcus multilocularis serotonin receptor 0.0135 0.1497 0.1542
Onchocerca volvulus 0.003 0.0268 0.1021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0336 0.0499
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Onchocerca volvulus Brd8 homolog 0.0009 0.0027 0.0102
Brugia malayi polybromodomain protein 0.0009 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0336 0.0499
Schistosoma mansoni hypothetical protein 0.0008 0.0006 0.0007
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.1231 0.4298
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.013 0.0117
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0365 0.4323
Trypanosoma cruzi ISWI complex protein 0.0015 0.0093 0.0365
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0658 0.7651 1
Leishmania major hypothetical protein, conserved 0.0009 0.0027 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0068 0.0071
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0365 0.1254
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0336 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Onchocerca volvulus 0.0017 0.0114 0.0434
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0658 0.7651 1
Brugia malayi 6-phosphofructokinase 0.0112 0.1231 0.1827
Trypanosoma brucei calpain, putative 0.0224 0.2549 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.013 0.017
Brugia malayi follicle stimulating hormone receptor 0.0489 0.5664 0.8407
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0336 0.035
Echinococcus granulosus g protein coupled receptor 0.0025 0.021 0.021
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0088 0.0946 0.3596
Trypanosoma brucei Bromodomain factor 1 0.0009 0.0027 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0365 0.1386
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0135 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.1231 0.1281
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Leishmania major RNA-editing complex protein MP100, putative 0.0008 0.0006 0.0025
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Echinococcus multilocularis fmrfamide receptor 0.0025 0.021 0.0216
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Schistosoma mansoni CREB-binding protein 2 0.0009 0.0027 0.0028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Leishmania major endonuclease/exonuclease protein-like protein 0.0008 0.0006 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0365 0.0425
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0271 0.2866
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0126 0.1399 0.1399
Trypanosoma brucei ISWI complex protein 0.0015 0.0093 0.0365
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1231 0.468
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0114 0.0119
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0271 0.0354
Echinococcus multilocularis DNA directed RNA polymerase III subunit RPC2 0.0013 0.0068 0.007
Loa Loa (eye worm) histone methyltransferase 0.001 0.0037 0.0066
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0336 0.0594
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Onchocerca volvulus 0.0026 0.0224 0.0851
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.1231 0.2174
Onchocerca volvulus 0.002 0.0154 0.0587
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0336 0.1278
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Brugia malayi neuropeptide F receptor 0.0025 0.021 0.0311
Echinococcus multilocularis synaptojanin 1 0.0008 0.0006 0.0007
Schistosoma mansoni helicase 0.0009 0.0027 0.0028
Schistosoma mansoni myosin xvIII 0.0025 0.021 0.0218
Brugia malayi sulfakinin receptor protein 0.0025 0.021 0.0311
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0271 0.0354
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0203 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Brugia malayi AKH receptor 0.0025 0.021 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0584 0.0601
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0006 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi ATPase, AAA family protein 0.0009 0.0027 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Plasmodium vivax bromodomain protein, putative 0.0009 0.0027 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0041 0.0162
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0203 0.0265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0012 0.0062 0.0027
Onchocerca volvulus 0.0025 0.021 0.0797
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0336 0.0499
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Schistosoma mansoni adenoreceptor 0.0025 0.021 0.0218
Brugia malayi hypothetical protein 0.002 0.0154 0.0229
Plasmodium falciparum DNA-directed RNA polymerase III subunit RPC2, putative 0.0013 0.0068 0.0089
Schistosoma mansoni synaptojanin 0.0008 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Mycobacterium tuberculosis Probable exported protein 0.0008 0.0006 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0265 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Mycobacterium ulcerans arylsulfatase, AslA 0.0008 0.0014 0.0018
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0265 0.0273
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0489 0.5664 1
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Echinococcus granulosus L aminoadipate semialdehyde 0.0044 0.0436 0.0436
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0138 0.0541
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Schistosoma mansoni neuropeptide receptor 0.0025 0.021 0.0218
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0271 0.3194
Schistosoma mansoni hypothetical protein 0.0009 0.0027 0.0028
Echinococcus multilocularis polybromo 1 0.0009 0.0027 0.0028
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0336 0.0346
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.2549 1
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0006 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi Dopamine receptor protein 2 0.0025 0.021 0.0311
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0027 0.0283
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.0114 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Onchocerca volvulus 0.0025 0.021 0.0797
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0041 0.0162
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0571 0.0747
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.021 0.0216
Echinococcus multilocularis Bromodomain containing protein 0.0009 0.0027 0.0028
Brugia malayi Dopamine receptor protein 1 0.0025 0.021 0.0311
Echinococcus multilocularis neuropeptide s receptor 0.0025 0.021 0.0216
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.1231 0.483
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0027 0.0105
Echinococcus granulosus lamin dm0 0.0026 0.0224 0.0224
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0114 0.0169
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0013 0.0068 0.0741
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0135 0.014
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0197 0.0205
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Brugia malayi polybromodomain protein 0.0009 0.0027 0.004
Onchocerca volvulus 0.0025 0.021 0.0797
Schistosoma mansoni cript-related 0.0008 0.0006 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0012 0.0062 0.0027
Echinococcus multilocularis microtubule associated protein 2 0.0367 0.4232 0.436
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0336 0.0336
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0025 0.021 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0365 0.0477
Echinococcus granulosus peregrin 0.0009 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.013 0.023
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0009 0.0027 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0135 0.02
Loa Loa (eye worm) hypothetical protein 0.0018 0.013 0.023
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0336 0.0499
Echinococcus granulosus g protein coupled receptor 0.0025 0.021 0.021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Schistosoma mansoni ap endonuclease 0.0038 0.0365 0.0379
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0135 0.014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.021 0.0216
Toxoplasma gondii DNA-directed RNA polymerase III RPC2 0.0013 0.0068 0.0717
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.021 0.021
Plasmodium falciparum histone acetyltransferase GCN5 0.0078 0.0835 0.1092
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0041 0.0421
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0332 0.0332
Brugia malayi DNA-directed RNA polymerase, beta subunit family protein 0.0013 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0104
Echinococcus multilocularis DNA directed RNA polymerase I subunit RPA2 0.0013 0.0068 0.007
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0006 0.0052
Leishmania major cathepsin L-like protease 0.0019 0.0138 0.0541
Brugia malayi nuclear receptor RXR 0.0019 0.0138 0.0205
Brugia malayi glutathione reductase 0.0031 0.0278 0.0413
Echinococcus granulosus 7TM GPCR rhodopsin 0.0025 0.021 0.021
Schistosoma mansoni opsin-like receptor 0.0025 0.021 0.0218
Brugia malayi nuclear receptor RXR 0.0017 0.0114 0.0169
Echinococcus multilocularis lamin dm0 0.0026 0.0224 0.0231
Onchocerca volvulus 0.0025 0.021 0.0797
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0271 0.2866
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0135 0.0238
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis hypothetical protein 0.0009 0.0027 0.0102
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0203 0.0265
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0011 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Trypanosoma brucei RNA polymerase I second largest subunit 0.0009 0.0025 0.0098
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0155 0.0273
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0203 0.0301
Brugia malayi Bromodomain containing protein 0.0083 0.0888 0.1319
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.021 0.021
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Brugia malayi ecdysone receptor 0.0017 0.0114 0.0169
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.1231 0.2174
Plasmodium falciparum thioredoxin reductase 0.0011 0.0041 0.0054
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0006 0.0007
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0527 0.0931
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus multilocularis g protein coupled receptor 0.0025 0.021 0.0216
Onchocerca volvulus 0.003 0.0265 0.1006
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.1231 0.1231
Brugia malayi nuclear hormone receptor 0.0036 0.0336 0.0499
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0006 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0017 0.0114 0.0114
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0017 0.0114 0.0118
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0041 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0203 0.0795
Echinococcus granulosus DNA directed RNA polymerase II subunit RPB2 0.0013 0.0068 0.0068
Onchocerca volvulus 0.0025 0.021 0.0797
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0658 0.7651 1
Echinococcus granulosus g protein coupled receptor 0.0025 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0336 0.0336
Brugia malayi hypothetical protein 0.0019 0.0138 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0336 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0135 0.014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0244 0.0244
Mycobacterium ulcerans sulfatase 0.0008 0.0014 0.0018
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.013 0.017
Schistosoma mansoni growth hormone secretagogue receptor 0.0025 0.021 0.0218
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0025 0.021 0.0216
Echinococcus granulosus Bromodomain containing protein 0.0009 0.0027 0.0027
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.0114 0.0119
Onchocerca volvulus 0.0025 0.021 0.0797
Echinococcus multilocularis lamin 0.0026 0.0224 0.0231
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0336 0.0346
Echinococcus granulosus neuropeptide s receptor 0.0025 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trypanosoma cruzi ISWI complex protein 0.0015 0.0093 0.0365
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0336 0.0336
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0009 0.0027 0.0102
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0571 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0513
Schistosoma mansoni phd finger protein 0.0009 0.0027 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.021 0.0216
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.021 0.021
Echinococcus granulosus lamin 0.0026 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Plasmodium vivax bromodomain protein, putative 0.0009 0.0027 0.0035
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.1231 0.483
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0135 0.0139
Echinococcus granulosus somatostatin receptor 0.0025 0.021 0.021
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) bromodomain containing protein 0.0009 0.0027 0.0047
Schistosoma mansoni polycystin 1-related 0.002 0.0154 0.0161
Schistosoma mansoni hypothetical protein 0.0825 0.9614 1
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0197 0.0197
Echinococcus granulosus DNA directed RNA polymerase I subunit RPA2 0.0013 0.0068 0.0068
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0027 0.0102
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.1231 0.4285
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0027 0.0105
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.021 0.0218
Schistosoma mansoni histamine h1 receptor 0.0025 0.021 0.0218
Echinococcus multilocularis expressed protein 0.0363 0.4182 0.4308
Schistosoma mansoni polybromo-1 0.0009 0.0027 0.0028
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0135 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0243
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0017 0.0119 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0047 0.0471 0.0832
Onchocerca volvulus Neuropeptide F receptor homolog 0.0025 0.021 0.0797
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0114 0.0118
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0271 0.0302
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0006 0.0024
Echinococcus multilocularis DNA directed RNA polymerase II subunit RPB2 0.0013 0.0068 0.007
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus expressed protein 0.0363 0.4182 0.4182
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Loa Loa (eye worm) DR-78 0.0017 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Brugia malayi Bromodomain containing protein 0.0009 0.0027 0.004
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.021 0.0216
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0224 0.0395
Echinococcus multilocularis G protein coupled receptor 139 0.0025 0.021 0.0216
Brugia malayi nuclear receptor NHR-88 0.0017 0.0114 0.0169
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus DNA directed RNA polymerase III subunit RPC2 0.0013 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0126 0.1399 0.1455
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0243
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0012 0.0062 0.0195
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0571 0.0589
Onchocerca volvulus 0.0231 0.2631 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0332 0.0342
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0068 0.0717 0.0937
Brugia malayi hypothetical protein 0.0008 0.0014 0.0021
Schistosoma mansoni nuclear receptor 0.0017 0.0114 0.0119
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0009 0.0027 0.0105
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0251 0.2864 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0006 0.0009
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Echinococcus granulosus Bromodomain containing protein 0.0009 0.0027 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0135 0.014
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0006 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0203 0.1646
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0462 0.0481
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0271 0.1031
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Plasmodium falciparum bromodomain protein 1 0.0009 0.0027 0.0035
Schistosoma mansoni biogenic amine receptor 0.0025 0.021 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0336 0.0499
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0006 0.0006
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.1231 0.1609
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Schistosoma mansoni retinoic acid receptor RXR 0.0036 0.0336 0.035
Brugia malayi Doublecortin family protein 0.002 0.0154 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Echinococcus granulosus allatostatin A receptor 0.0025 0.021 0.021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0336 0.0346
Echinococcus multilocularis Bromodomain containing protein 0.0009 0.0027 0.0028
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0037 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus g-protein coupled receptor 0.0025 0.021 0.021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.013 0.017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0336 0.0346
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0113 0.0118
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0009 0.0027 0.0283
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0197 0.0203
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0025 0.021 0.0311
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0025 0.021 0.0218
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) doublecortin family protein 0.002 0.0154 0.0273
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0027 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0025 0.021 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Brugia malayi Pre-SET motif family protein 0.003 0.0265 0.0393
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0114 0.0169
Plasmodium falciparum glutathione reductase 0.0011 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.013 0.023
Brugia malayi hypothetical protein 0.0019 0.0135 0.02
Mycobacterium tuberculosis Probable sulfatase 0.0008 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Brugia malayi CCR4 0.0008 0.0006 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0135 0.0139
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.021 0.037
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0365 0.0644
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0065 0.0065
Loa Loa (eye worm) glutathione reductase 0.0031 0.0278 0.0491
Brugia malayi Sulfatase family protein 0.0008 0.0014 0.0021
Trypanosoma brucei hypothetical protein 0.0224 0.2549 1
Mycobacterium tuberculosis Possible hydrolase 0.0008 0.0014 0.0018
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0025 0.021 0.0218
Schistosoma mansoni zinc finger protein 0.0017 0.0114 0.0119
Plasmodium vivax glutathione reductase, putative 0.0031 0.0278 0.0363
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.092 0.7475
Brugia malayi larval opioid receptor 0.0025 0.021 0.0311
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.021 0.0216
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0154 0.0202
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0154 0.0159
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0135 0.0139
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0271 0.0302
Trypanosoma cruzi bromodomain-containing protein 3 0.0009 0.0027 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0135 0.0513
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0009 0.0027 0.0028
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0251 0.2864 0.371
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0006 0.0024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0138 0.0541
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0135 0.0135
Echinococcus multilocularis g protein coupled receptor 0.0025 0.021 0.0216
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Mycobacterium tuberculosis Probable oxidoreductase 0.0011 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0358
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0135 0.0238
Schistosoma mansoni amine GPCR 0.0218 0.2475 0.2574
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0018 0.013 0.023
Leishmania major trypanothione reductase 0.0031 0.0278 0.109
Trichomonas vaginalis lymphoid specific helicase, putative 0.0009 0.0027 0.0102
Brugia malayi conserved hypotetical protein 0.0017 0.0114 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0135 0.0238
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0658 0.7651 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.1497 0.2642
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.021 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0309 0.3541 0.6253
Echinococcus multilocularis orexin receptor type 2 0.0025 0.021 0.0216
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Entamoeba histolytica bromodomain-containing protein 0.0009 0.0027 0.0217
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0154 0.0159
Trypanosoma cruzi major cysteine proteinase, putative 0.0015 0.009 0.0355
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0138 0.0143
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0135 0.0135
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0365 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0041 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.021 0.0216
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0203 0.0708
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0365 0.0376
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0203 0.0265
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0203 0.0265
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0243
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0135 0.0139
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0365 0.0365
Schistosoma mansoni lipoxygenase 0.002 0.0154 0.0161
Giardia lamblia DNA-directed RNA polymerase RPB2 0.0013 0.0068 0.0741
Echinococcus multilocularis neuropeptide receptor 0.0025 0.021 0.0216
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0037 0.0037
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0708 0.7478
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0006 0.0052
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0224 0.2549 1
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0068 0.0258
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0009 0.0027 0.0102
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0571 0.0747
Trypanosoma brucei DNA-directed RNA polymerase II subunit 2, putative 0.0013 0.0068 0.0266
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.092 0.7475
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0135 0.0139
Brugia malayi G-protein coupled receptor 0.0025 0.021 0.0311
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0012 0.0062 0.0656
Schistosoma mansoni DNA-directed RNA polymerase I subunit 0.0009 0.0025 0.0026
Brugia malayi GnHR receptor homolog 0.0025 0.021 0.0311
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0041 0.0162
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0135 0.014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0025 0.021 0.0311
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0336 0.1278
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0025 0.021 0.0218
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0044 0.0436 0.0453
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0006 0.0007
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0154 0.0159
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0365 0.2962
Schistosoma mansoni coup transcription factor 0.0036 0.0336 0.035
Echinococcus multilocularis dro:myosuppressin receptor 0.0025 0.021 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0006 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0462 0.0481
Trichomonas vaginalis hypothetical protein 0.0009 0.0027 0.0102
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0041 0.0061
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.1497 0.1497
Plasmodium vivax bromodomain protein, putative 0.0009 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0041 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0271 0.1031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0358
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0006 0.0025
Onchocerca volvulus 0.0025 0.021 0.0797
Schistosoma mansoni lamin 0.0026 0.0224 0.0233
Brugia malayi hypothetical protein 0.0017 0.0114 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0135 0.0139
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0008 0.0006 0.0025
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0135 0.0238
Entamoeba histolytica acetyltransferase, GNAT family 0.0078 0.0835 0.6784
Entamoeba histolytica hypothetical protein 0.0009 0.0027 0.0217
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.021 0.0218
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2302 0.4065
Onchocerca volvulus 0.0025 0.021 0.0797
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0009 0.0027 0.0102
Brugia malayi ecdysteroid receptor 0.0036 0.0336 0.0499
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0271 0.0354
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0068 0.0551
Schistosoma mansoni hypothetical protein 0.002 0.0154 0.0161
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2631 1
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0336 0.035
Leishmania major cathepsin L-like protease 0.0019 0.0138 0.0541
Leishmania major RNA polymerase I second largest subunit, putative 0.0009 0.0025 0.0098
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0336 0.035
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0015 0.0093 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0138 0.0541
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0006 0.0052
Brugia malayi RE15519p 0.0025 0.021 0.0311
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Schistosoma mansoni amine GPCR 0.0025 0.021 0.0218
Brugia malayi Cytochrome P450 family protein 0.0024 0.0194 0.0287
Schistosoma mansoni amine GPCR 0.0025 0.021 0.0218
Schistosoma mansoni rab6-interacting 0.002 0.0154 0.0161
Brugia malayi Thioredoxin reductase 0.0031 0.0278 0.0413
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.001 0.0039 0.0148
Entamoeba histolytica hypothetical protein 0.0019 0.0135 0.1095
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0041 0.0162
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0006 0.0024
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0009 0.0027 0.0283
Echinococcus granulosus neuropeptide FF receptor 2 0.0025 0.021 0.021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0162 0.182 0.1875
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) hypothetical protein 0.0025 0.021 0.037
Trypanosoma brucei DNA-directed RNA polymerase III, putative 0.0013 0.0068 0.0266
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0031 0.0278 0.0363
Loa Loa (eye worm) hypothetical protein 0.0009 0.0027 0.0047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0336 0.0346
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0016 0.0016
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.092 0.7475
Echinococcus granulosus bromodomain containing protein 8 0.0009 0.0027 0.0027
Schistosoma mansoni neuropeptide f receptor 76f 0.0025 0.021 0.0218
Brugia malayi bromodomain containing protein 0.0009 0.0027 0.004
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0135 0.014
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0271 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0201
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0006 0.0011
Brugia malayi Serotonin receptor 0.0025 0.021 0.0311
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0088 0.0946 1
Brugia malayi hypothetical protein 0.0025 0.021 0.0311
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0365 0.0541
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0118 0.0155
Loa Loa (eye worm) hypothetical protein 0.004 0.0382 0.0675
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0114 0.0114
Echinococcus multilocularis allatostatin A receptor 0.0025 0.021 0.0216
Loa Loa (eye worm) acetyltransferase 0.0293 0.3354 0.5921
Schistosoma mansoni hypothetical protein 0.0025 0.021 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0336 0.0594
Loa Loa (eye worm) thioredoxin reductase 0.0031 0.0278 0.0491
Schistosoma mansoni cpg binding protein 0.003 0.0268 0.0279
Toxoplasma gondii exonuclease III APE 0.0038 0.0365 0.3854
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0006 0.0025
Brugia malayi Serotonin receptor 0.0581 0.6737 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0138 0.0143
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Echinococcus multilocularis zinc finger protein 0.0028 0.0246 0.0254
Loa Loa (eye worm) melatonin receptor type 1A 0.0025 0.021 0.037
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0011 0.0041 0.0054
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0008 0.0014 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0224 0.2549 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0025 0.021 0.0311
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0135 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0027 0.0102
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0006 0.0025
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0009 0.0027 0.0027
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0012 0.0062 0.0081
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0006 0.0025
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0006 0.0008
Toxoplasma gondii hypothetical protein 0.004 0.0382 0.4039
Entamoeba histolytica hypothetical protein 0.0019 0.0135 0.1095
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0008 0.0014 0.0018
Onchocerca volvulus 0.0025 0.021 0.0797
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0113 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0027 0.0102

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = -7.5 In vitro binding affinity at human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by [3H]-mesulergine displacement. ChEMBL. 10969987
Ki (binding) = -6 In vitro binding affinity at human cloned 5-hydroxytryptamine 2B receptor of HEK293 cells by [3H]-5-HT displacement. ChEMBL. 10969987
Ki (binding) > -5.3 In vitro binding affinity at human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by [3H]-ketanserin displacement. ChEMBL. 10969987
Log Ki (binding) > 5.3 In vitro binding affinity at human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by [3H]-ketanserin displacement. ChEMBL. 10969987
Log Ki (binding) = 6 In vitro binding affinity at human cloned 5-hydroxytryptamine 2B receptor of HEK293 cells by [3H]-5-HT displacement. ChEMBL. 10969987
Log Ki (binding) = 7.5 In vitro binding affinity at human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by [3H]-mesulergine displacement. ChEMBL. 10969987
Selectivity (binding) = 30 Selectivity at serotonin 5-HT 2C receptor compared to serotonin 5-HT 2B receptor ChEMBL. 10969987
Selectivity (binding) > 160 Selectivity at 5-HT 2C receptor compared to serotonin 5-HT 2A receptor ChEMBL. 10969987

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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