Detailed information for compound 830218

Basic information

Technical information
  • TDR Targets ID: 830218
  • Name: 2-(4-methyl-1-oxophthalazin-2-yl)-N-(4-methyl sulfanylphenyl)acetamide
  • MW: 339.411 | Formula: C18H17N3O2S
  • H donors: 1 H acceptors: 2 LogP: 2.62 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1ccc(cc1)NC(=O)Cn1nc(C)c2c(c1=O)cccc2
  • InChi: 1S/C18H17N3O2S/c1-12-15-5-3-4-6-16(15)18(23)21(20-12)11-17(22)19-13-7-9-14(24-2)10-8-13/h3-10H,11H2,1-2H3,(H,19,22)
  • InChiKey: HRGNZDFSSPETRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(4-methyl-1-oxo-phthalazin-2-yl)-N-(4-methylsulfanylphenyl)acetamide
  • 2-(4-methyl-1-oxo-2-phthalazinyl)-N-[4-(methylthio)phenyl]acetamide
  • 2-(1-keto-4-methyl-phthalazin-2-yl)-N-[4-(methylthio)phenyl]acetamide
  • 2-(4-methyl-1-oxo-phthalazin-2-yl)-N-(4-methylsulfanylphenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni integrin alpha-ps 0.0547 0.0643 0.0799
Schistosoma mansoni protein kinase 0.0133 0.013 0.0162
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0719 0.0856 0.1065
Loa Loa (eye worm) integrin alpha pat-2 0.2617 0.3206 0.3206
Echinococcus multilocularis integrin alpha ps 0.0987 0.1188 0.161
Loa Loa (eye worm) hypothetical protein 0.0057 0.0036 0.0036
Toxoplasma gondii subtilisin SUB11 0.0286 0.032 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0191 0.0202 0.0201
Plasmodium falciparum plasmepsin V 0.0129 0.0125 0.3739
Brugia malayi hypothetical protein 0.0044 0.002 0.0019
Toxoplasma gondii subtilisin SUB6 0.0286 0.032 1
Giardia lamblia Neurogenic locus notch-like protein 0.0191 0.0202 0.0683
Schistosoma mansoni protein kinase 0.0133 0.013 0.0162
Loa Loa (eye worm) WD40 repeat protein 0.0134 0.0131 0.013
Echinococcus granulosus lysine specific histone demethylase 1A 0.0069 0.0051 0.0062
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Echinococcus multilocularis chromatin regulatory protein sir2 0.0326 0.0369 0.0499
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0079 0.0063 0.5
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.006 0.0039 0.1036
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Leishmania major subtilisin-like serine peptidase 0.0286 0.032 0.8573
Brugia malayi Subtilase family protein 0.0286 0.032 0.0319
Brugia malayi Will die slowly protein 0.0134 0.0131 0.013
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Brugia malayi pregnancy-associated plasma protein-A 0.0035 0.0008 0.0007
Echinococcus multilocularis c4b binding protein beta chain 0.0035 0.0008 0.001
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0139 0.0137 0.017
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0301 0.0338 0.9099
Plasmodium vivax subtilisin-like protease 2, putative 0.0286 0.032 1
Loa Loa (eye worm) hypothetical protein 0.0191 0.0202 0.0201
Brugia malayi angiogenesis inhibito 0.0081 0.0066 0.0065
Giardia lamblia Furin precursor putative serine protease 0.1295 0.1569 0.5336
Onchocerca volvulus 0.0134 0.0131 0.2972
Loa Loa (eye worm) hypothetical protein 0.0069 0.0051 0.005
Plasmodium vivax subtilisin-like serine protease, putative 0.0286 0.032 1
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0081 0.0065 0.1864
Echinococcus granulosus glutamate receptor subunit protein glur 0.0031 0.0003 0.0003
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0286 0.032 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Toxoplasma gondii subtilisin SUB12 0.0286 0.032 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0048 0.0025 0.0024
Mycobacterium ulcerans thioesterase 0.0069 0.0051 0.0897
Echinococcus granulosus integrin alpha 3 0.1358 0.1647 0.2048
Loa Loa (eye worm) angiogenesis inhibito 0.0038 0.0013 0.0012
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0326 0.0369 0.0458
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0004
Schistosoma mansoni furin-1 (S08 family) 0.2821 0.3459 0.4304
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0057 0.0036 0.0044
Schistosoma mansoni hypothetical protein 0.0057 0.0036 0.0045
Mycobacterium ulcerans polyketide synthase Pks9 0.0052 0.003 0.0169
Plasmodium falciparum subtilisin-like protease 2 0.0286 0.032 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0326 0.0369 0.0751
Onchocerca volvulus 0.0368 0.0421 1
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.3983 0.4898 0.6093
Brugia malayi celfurPC protein 0.5223 0.6434 0.6433
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0038 0.0013 0.0016
Schistosoma mansoni chromatin regulatory protein sir2 0.0326 0.0369 0.0459
Plasmodium vivax subtilisin-like protease 1 0.0286 0.032 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.002 0.0019
Giardia lamblia hypothetical protein 0.0191 0.0202 0.0683
Schistosoma mansoni ATP-binding cassette transporter 0.0031 0.0003 0.0004
Schistosoma mansoni chromatin regulatory protein sir2 0.0048 0.0025 0.0031
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Schistosoma mansoni tyrosine kinase 0.0385 0.0443 0.0551
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0326 0.0369 1
Plasmodium falciparum subtilisin-like protease 3 0.0286 0.032 1
Mycobacterium ulcerans polyketide synthase Pks13 0.0121 0.0116 0.3085
Brugia malayi Integrin alpha pat-2 precursor 0.1836 0.2239 0.2238
Echinococcus granulosus c4b binding protein beta chain 0.0035 0.0008 0.0009
Echinococcus multilocularis growth factor receptor bound protein 2 0.0123 0.0118 0.0159
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0085 0.0071 0.2052
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0301 0.0338 0.9099
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0062 0.0061
Giardia lamblia Tenascin-37 0.0191 0.0202 0.0683
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.032 0.0651
Schistosoma mansoni dihydroceramide desaturase 0.0057 0.0036 0.0045
Echinococcus multilocularis protein will die slowly 0.0134 0.0131 0.0177
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0118 0.0147
Onchocerca volvulus 0.0145 0.0145 0.3306
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Brugia malayi Disintegrin family protein 0.0057 0.0036 0.0036
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0031 0.0003 0.0003
Echinococcus granulosus integrin alpha ps 0.044 0.0511 0.0634
Echinococcus multilocularis C type lectin domian containing protein 0.0035 0.0008 0.001
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0286 0.032 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0048 0.0025 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0242 0.0265 0.0358
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Toxoplasma gondii subtilisin SUB9 0.0286 0.032 1
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.1295 0.1569 0.3202
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0025 0.0533
Loa Loa (eye worm) integrin beta-2 0.8102 1 1
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0286 0.032 0.0319
Toxoplasma gondii hypothetical protein 0.0191 0.0202 0.6298
Loa Loa (eye worm) hypothetical protein 0.0191 0.0202 0.0201
Echinococcus granulosus disintegrin and metalloproteinase 0.0057 0.0036 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0048 0.0025 0.0651
Echinococcus granulosus MAM 0.0044 0.002 0.0024
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0101 0.0124
Loa Loa (eye worm) hypothetical protein 0.0098 0.0086 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Echinococcus multilocularis integrin beta 2 0.5983 0.7376 1
Loa Loa (eye worm) hypothetical protein 0.0368 0.0421 0.0421
Brugia malayi EGF-like domain containing protein 0.0191 0.0202 0.0201
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0069 0.0051 0.088
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0003 0.0004
Schistosoma mansoni SWI/SNF complex-related 0.0029 0.0001 0.0001
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.008 0.0065 0.1847
Echinococcus multilocularis Furin 1 0.1581 0.1923 0.2607
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0286 0.032 0.0398
Onchocerca volvulus 0.0078 0.0062 0.1294
Onchocerca volvulus 0.0191 0.0202 0.468
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0069 0.0051 0.1565
Toxoplasma gondii rhoptry neck protein RON9 0.0035 0.0008 0.0231
Brugia malayi metalloprotease 0.0038 0.0013 0.0012
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0286 0.032 1
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0031 0.0003 0.0003
Loa Loa (eye worm) transcriptional regulator 0.0326 0.0369 0.0368
Echinococcus multilocularis protein kinase c epsilon type 0.0084 0.0069 0.0093
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0242 0.0265 0.0264
Toxoplasma gondii type I fatty acid synthase, putative 0.0085 0.0071 0.2205
Mycobacterium ulcerans thioesterase TesA 0.0069 0.0051 0.0897
Brugia malayi Stress-activated protein kinase jnk-1 0.0242 0.0265 0.0264
Trichomonas vaginalis WD repeat domain, putative 0.0134 0.0131 0.0266
Loa Loa (eye worm) hypothetical protein 0.0087 0.0073 0.0072
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0057 0.0036 0.0036
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0085 0.0071 0.2052
Loa Loa (eye worm) hypothetical protein 0.1396 0.1694 0.1693
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.1295 0.1569 0.3202
Onchocerca volvulus Fatty acid synthase homolog 0.015 0.0151 0.3461
Mycobacterium ulcerans polyketide synthase 0.008 0.0065 0.1354
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Schistosoma mansoni amine oxidase 0.0069 0.0051 0.0063
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0085 0.0071 0.1427
Giardia lamblia Tenascin-X 0.0191 0.0202 0.0683
Loa Loa (eye worm) hypothetical protein 0.6518 0.8037 0.8037
Echinococcus granulosus serine:threonine protein kinase N2 0.0069 0.005 0.0062
Loa Loa (eye worm) proprotein convertase 2 0.1581 0.1923 0.1923
Loa Loa (eye worm) hypothetical protein 0.1242 0.1504 0.1503
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0069 0.0086
Mycobacterium ulcerans polyketide synthase 0.0085 0.0071 0.1572
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0052 0.003 0.0169
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0023 0.003
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0326 0.0369 1
Toxoplasma gondii rhoptry neck protein RON1 0.0035 0.0008 0.0231
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Loa Loa (eye worm) glutamate receptor 2 0.0031 0.0003 0.0002
Echinococcus multilocularis fibrillin 2 0.0191 0.0202 0.0272
Echinococcus multilocularis protoporphyrinogen oxidase 0.0069 0.0051 0.0068
Trypanosoma cruzi UDP-galactopyranose mutase 0.0069 0.0051 0.0755
Giardia lamblia Neurogenic locus Notch protein precursor 0.0191 0.0202 0.0683
Echinococcus multilocularis protein jagged 2 0.0191 0.0202 0.0272
Giardia lamblia Transcriptional regulator, Sir2 family 0.0048 0.0025 0.0081
Loa Loa (eye worm) fatty acid synthase 0.0082 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.034 0.0386 0.0385
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0048 0.0025 0.0032
Brugia malayi Sushi domain 0.0035 0.0008 0.0007
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0048 0.0025 0.0032
Giardia lamblia Hypothetical protein 0.0326 0.0369 0.1252
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0057 0.0036 0.0048
Loa Loa (eye worm) hypothetical protein 0.0191 0.0202 0.0201
Echinococcus granulosus integrin alpha ps 0.0987 0.1188 0.1477
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0035 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.001
Plasmodium vivax NAD-dependent deacetylase, putative 0.0048 0.0025 0.0533
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0069 0.0051 0.1366
Echinococcus multilocularis lysine specific histone demethylase 1A 0.034 0.0386 0.0522
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0031 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.032 0.0651
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0301 0.0338 0.9099
Echinococcus granulosus lysine specific histone demethylase 1A 0.034 0.0386 0.0479
Brugia malayi Glutamate receptor 2 precursor 0.0031 0.0003 0.0002
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0286 0.032 1
Schistosoma mansoni integrin alpha-ps 0.0919 0.1103 0.1372
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0031 0.0003 0.0003
Brugia malayi EGF-like domain containing protein 0.0191 0.0202 0.0201
Schistosoma mansoni septate junction protein 0.0034 0.0007 0.0009
Schistosoma mansoni integrin beta subunit 0.4741 0.5837 0.7263
Toxoplasma gondii histone deacetylase SIR2-like 0.0048 0.0025 0.0751
Echinococcus granulosus Furin 1 0.1581 0.1923 0.2392
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0023 0.0027
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0069 0.0051 0.088
Loa Loa (eye worm) hypothetical protein 0.0069 0.0051 0.005
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0069 0.0051 0.1366
Echinococcus granulosus integrin beta 2 0.5983 0.7376 0.9177
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0069 0.0051 0.1366
Loa Loa (eye worm) hypothetical protein 0.034 0.0386 0.0385
Loa Loa (eye worm) reprolysin 0.0139 0.0137 0.0136
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0048 0.0025 0.0533
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0048 0.0025 0.0569
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.008 0.0065 0.1206
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0069 0.0051 0.0063
Brugia malayi EGF-like domain containing protein 0.0191 0.0202 0.0201
Toxoplasma gondii subtilisin SUB5 0.0286 0.032 1
Toxoplasma gondii subtilisin SUB2 0.0286 0.032 1
Brugia malayi ADAM-TS Spacer 1 family protein 0.0081 0.0066 0.0065
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0139 0.0137 0.017
Echinococcus multilocularis neuroendocrine convertase 2 0.4116 0.5063 0.6864
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0003 0.0004
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0123 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0081 0.0066 0.0065
Mycobacterium leprae Probable polyketide synthase Pks1 0.0085 0.0071 0.1427
Brugia malayi Angiotensin-converting enzyme family protein 0.0608 0.0718 0.0717
Loa Loa (eye worm) hypothetical protein 0.0547 0.0643 0.0642
Echinococcus granulosus glutamate NMDA receptor subunit 0.0259 0.0286 0.0355
Toxoplasma gondii histone deacetylase SIR2 0.0048 0.0025 0.0751
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0191 0.0202 0.041
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Schistosoma mansoni hypothetical protein 0.0057 0.0036 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Brugia malayi endoprotease bli-4 precursor 0.6518 0.8037 0.8037
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.032 0.0651
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0023 0.0027
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0326 0.0369 1
Brugia malayi ADAMTS-like protease 0.0081 0.0066 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.032 0.0651
Mycobacterium tuberculosis Probable thioesterase TesA 0.0069 0.0051 0.1415
Brugia malayi hypothetical protein 0.1242 0.1504 0.1503
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0031 0.0003 0.0003
Echinococcus multilocularis 0.0069 0.0051 0.0068
Schistosoma mansoni apoptosis regulator bax 0.0057 0.0036 0.0045
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0286 0.032 0.0432
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3983 0.4898 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0326 0.0369 0.0368
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0057 0.0036 0.0044
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0101 0.0136
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Loa Loa (eye worm) hypothetical protein 0.129 0.1563 0.1562
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0259 0.0286 0.0387
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0079 0.0063 0.129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0012
Brugia malayi Glutamate receptor 1 precursor 0.0031 0.0003 0.0002
Echinococcus granulosus neuroendocrine convertase 2 0.4116 0.5063 0.6299
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Brugia malayi Sex muscle abnormal protein 5 0.0123 0.0118 0.0117
Echinococcus granulosus chromatin regulatory protein sir2 0.0326 0.0369 0.0458
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Brugia malayi protein kinase C II. 0.0084 0.0069 0.0069
Echinococcus granulosus protein kinase c epsilon type 0.0084 0.0069 0.0085
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0608 0.0718 0.0717
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0085 0.0071 0.1572
Schistosoma mansoni protein kinase 0.0133 0.013 0.0162
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Loa Loa (eye worm) glutamate receptor 1 0.0031 0.0003 0.0002
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0048 0.0025 0.0651
Loa Loa (eye worm) hypothetical protein 0.0044 0.0019 0.0019
Echinococcus multilocularis integrin alpha ps 0.0919 0.1103 0.1494
Loa Loa (eye worm) hypothetical protein 0.0043 0.0018 0.0017
Echinococcus multilocularis epidermal growth factor receptor 0.0385 0.0443 0.0599
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0286 0.032 0.0319
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3983 0.4898 1
Echinococcus multilocularis NMDA receptor 0.0031 0.0003 0.0003
Giardia lamblia High cysteine protein 0.0191 0.0202 0.0683
Echinococcus granulosus growth factor receptor bound protein 2 0.0123 0.0118 0.0146
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0003 0.0004
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0181 0.019 0.0236
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0116 0.0109 0.0108
Toxoplasma gondii type I fatty acid synthase, putative 0.0059 0.0039 0.1188
Entamoeba histolytica PH domain containing protein kinase, putative 0.0069 0.005 0.1347
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0719 0.0856 0.116
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0034 0.0007 0.0009
Echinococcus multilocularis fibrillin 1 0.0205 0.022 0.0297
Echinococcus granulosus fibrillin 2 0.0191 0.0202 0.025
Brugia malayi amine oxidase, flavin-containing family protein 0.0098 0.0086 0.0085
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0057 0.0036 0.0045
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Giardia lamblia High cysteine protein 0.0191 0.0202 0.0683
Echinococcus multilocularis MAM 0.0044 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.001
Loa Loa (eye worm) transcriptional regulator 0.0048 0.0025 0.0024
Trypanosoma cruzi subtilisin peptidase 0.0286 0.032 0.8573
Schistosoma mansoni Lysine-specific histone demethylase 1 0.034 0.0386 0.048
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Onchocerca volvulus 0.0105 0.0095 0.2096
Toxoplasma gondii subtilisin SUB8 0.0286 0.032 1
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.1295 0.1569 0.3202
Echinococcus granulosus adam 17 protease 0.0057 0.0036 0.0044
Mycobacterium leprae Polyketide synthase Pks13 0.0121 0.0116 0.2966
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0078 0.0062 0.1749
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Loa Loa (eye worm) metalloprotease 0.0038 0.0013 0.0012
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0023 0.003
Loa Loa (eye worm) acyl carrier protein 0.0038 0.0013 0.0012
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0048 0.0025 0.003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0025 0.0024
Schistosoma mansoni glutamate receptor NMDA 0.0046 0.0023 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0031 0.0003 0.0003
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0046 0.0023 0.0027
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0085 0.0071 0.2052
Brugia malayi Kelch motif family protein 0.1257 0.1522 0.1521
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0042 0.0017 0.0519
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0064 0.0045 0.0671
Loa Loa (eye worm) hypothetical protein 0.0069 0.005 0.0049
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Plasmodium falciparum subtilisin-like protease 1 0.0286 0.032 1
Onchocerca volvulus 0.0044 0.002 0.0293
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0069 0.0051 0.1366
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0286 0.032 0.0397
Plasmodium falciparum protoporphyrinogen oxidase 0.0069 0.0051 0.1366
Echinococcus multilocularis 0.5223 0.6434 0.8723
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0048 0.0025 0.0081
Loa Loa (eye worm) TK/ALK protein kinase 0.0044 0.002 0.0019
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0023 0.003
Brugia malayi EGF-like domain containing protein 0.0191 0.0202 0.0201
Loa Loa (eye worm) endoprotease bli-4 0.6518 0.8037 0.8037
Echinococcus granulosus C type lectin domian containing protein 0.0035 0.0008 0.0009
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.008 0.0065 0.1354
Mycobacterium ulcerans oxidoreductase 0.0069 0.0051 0.088
Loa Loa (eye worm) apoptosis regulator protein 0.0057 0.0036 0.0036
Echinococcus granulosus furin 0.6518 0.8037 1
Brugia malayi hypothetical protein 0.0181 0.019 0.0189
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0048 0.0025 0.003
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0079 0.0063 0.5
Brugia malayi hypothetical protein 0.0069 0.0051 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.032 0.0651
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0051 0.1366
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0121 0.0116 0.3479
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0065 0.0046 0.1245
Chlamydia trachomatis glutamine binding protein 0.0079 0.0063 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.002 0.0019
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0069 0.0051 0.074
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0079 0.0063 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.008 0.0065 0.1847
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0326 0.0369 0.0499
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.3983 0.4898 0.664
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0054 0.0032 0.0983
Plasmodium vivax plasmepsin V, putative 0.0129 0.0125 0.3739
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0003 0.0004
Loa Loa (eye worm) kelch domain-containing protein family protein 0.1257 0.1522 0.1521
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0064 0.0045 0.0671
Giardia lamblia Tenascin-like 0.0191 0.0202 0.0683
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0037 0.0011 0.001
Schistosoma mansoni integrin alpha 0.1836 0.2239 0.2786
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0286 0.032 1
Toxoplasma gondii subtilisin SUB4 0.0286 0.032 1
Loa Loa (eye worm) hypothetical protein 0.0917 0.1101 0.1101
Loa Loa (eye worm) hypothetical protein 0.0044 0.002 0.0019
Trichomonas vaginalis hypothetical protein 0.0191 0.0202 0.041
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0084 0.0069 0.0069
Schistosoma mansoni chromatin regulatory protein sir2 0.0326 0.0369 0.0459
Loa Loa (eye worm) hypothetical protein 0.2535 0.3105 0.3104
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0326 0.0369 1
Schistosoma mansoni hypothetical protein 0.0134 0.0131 0.0163
Mycobacterium ulcerans monoamine oxidase 0.0069 0.0051 0.088
Loa Loa (eye worm) transcriptional regulator 0.0048 0.0025 0.0024
Giardia lamblia Tenascin precursor 0.0191 0.0202 0.0683
Echinococcus multilocularis glutamate receptor 2 0.0031 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Brugia malayi neuroendocrine convertase 1 precursor 0.4116 0.5063 0.5063
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.008 0.0065 0.1847
Loa Loa (eye worm) hypothetical protein 0.0139 0.0137 0.0136
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0048 0.0025 0.003
Loa Loa (eye worm) hypothetical protein 0.0286 0.032 0.0319
Onchocerca volvulus 0.0286 0.032 0.7536
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0057 0.0036 0.0048
Schistosoma mansoni hypothetical protein 0.0044 0.002 0.0025
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0047 0.0024 0.0542
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.6518 0.8037 1
Brugia malayi Protein kinase domain containing protein 0.0044 0.002 0.0019
Echinococcus granulosus epidermal growth factor receptor 0.0385 0.0443 0.055
Toxoplasma gondii histone lysine-specific demethylase 0.0069 0.0051 0.1565
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0069 0.0051 0.088
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0121 0.0116 0.3479
Giardia lamblia Sirtuin type 2 0.0048 0.0025 0.0081
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0109 0.0101 0.0136
Trypanosoma brucei subtilisin peptidase 0.0286 0.032 0.8573
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Echinococcus granulosus c-Jun N-terminal kinases 0.0242 0.0265 0.0328
Loa Loa (eye worm) sirtuin 4 0.0048 0.0025 0.0024
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0286 0.032 0.0398
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Echinococcus granulosus glutamate receptor 2 0.0046 0.0023 0.0027
Mycobacterium ulcerans dehydrogenase 0.0069 0.0051 0.088
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0223 0.0242 0.0301
Schistosoma mansoni chromatin regulatory protein sir2 0.0326 0.0369 0.0459
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0057 0.0036 0.0036
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1581 0.1923 0.3926
Brugia malayi NAD-dependent deacetylase SIRT1 0.0048 0.0025 0.0024
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0286 0.032 0.8573
Toxoplasma gondii subtilisin SUB1 0.0286 0.032 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Brugia malayi GCC2 and GCC3 family protein 0.0044 0.0019 0.0019
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0081 0.0065 0.1864
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0048 0.0025 0.0032
Schistosoma mansoni chromatin regulatory protein sir2 0.0048 0.0025 0.0031
Echinococcus multilocularis serine:threonine protein kinase N2 0.0077 0.0061 0.0081
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0064 0.0045 0.051
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Loa Loa (eye worm) hypothetical protein 0.0044 0.0019 0.0019
Schistosoma mansoni chromatin regulatory protein sir2 0.0048 0.0025 0.0031
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1229 0.1488 0.1851
Leishmania major silent information regulator 2, putative 0.0326 0.0369 1
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0286 0.032 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0046 0.0023 0.003
Brugia malayi Integrin alpha cytoplasmic region family protein 0.129 0.1563 0.1562
Schistosoma mansoni hypothetical protein 0.1295 0.1569 0.1952
Echinococcus granulosus adam 0.0372 0.0426 0.0529
Mycobacterium ulcerans Type I modular polyketide synthase 0.008 0.0065 0.1354
Schistosoma mansoni c4b-binding protein beta chain 0.0035 0.0008 0.001
Echinococcus multilocularis adam 0.0372 0.0426 0.0577
Loa Loa (eye worm) hypothetical protein 0.0081 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0137 0.0135 0.0134
Brugia malayi Reprolysin 0.0081 0.0066 0.0065
Schistosoma mansoni site-1 peptidase (S08 family) 0.0286 0.032 0.0398
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0025 0.0651
Leishmania major UDP-galactopyranose mutase 0.0069 0.0051 0.0755
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Echinococcus multilocularis disintegrin and metalloproteinase 0.0057 0.0036 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0265 0.0329
Mycobacterium tuberculosis Possible oxidoreductase 0.0069 0.0051 0.1399
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0118 0.0147
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0007
Trichomonas vaginalis hypothetical protein 0.1295 0.1569 0.3202
Mycobacterium ulcerans Type I modular polyketide synthase 0.008 0.0065 0.1354
Brugia malayi SWIRM domain containing protein 0.0368 0.0421 0.0421
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0286 0.032 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.013 0.0161
Toxoplasma gondii subtilisin SUB7 0.0286 0.032 1
Schistosoma mansoni hypothetical protein 0.0044 0.002 0.0025
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0085 0.0071 0.1572
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0048 0.0025 0.0049
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0286 0.032 1
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0085 0.0071 0.1427
Brugia malayi proprotein convertase 2 0.4116 0.5063 0.5063
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.1581 0.1923 0.2393
Trichomonas vaginalis conserved hypothetical protein 0.1295 0.1569 0.3202
Schistosoma mansoni amine oxidase 0.0069 0.0051 0.0063
Echinococcus multilocularis integrin alpha ps 0.044 0.0511 0.0691
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0051 0.1366
Schistosoma mansoni hypothetical protein 0.044 0.0511 0.0635
Loa Loa (eye worm) hypothetical protein 0.0509 0.0596 0.0595
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0326 0.0369 1
Echinococcus multilocularis integrin alpha 3 0.1358 0.1647 0.2232
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0155 0.0157 0.0156
Echinococcus granulosus membrane bound transcription factor site 1 0.0286 0.032 0.0397
Mycobacterium ulcerans Type I modular polyketide synthase 0.008 0.0065 0.1354
Schistosoma mansoni site-1 peptidase (S08 family) 0.0286 0.032 0.0398
Giardia lamblia High cysteine membrane protein Group 2 0.2402 0.294 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0385 0.0443 0.0442
Toxoplasma gondii aspartyl protease ASP5 0.0117 0.011 0.3439
Trypanosoma cruzi UDP-galactopyranose mutase 0.0069 0.0051 0.0755
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0048 0.0025 0.0533
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0079 0.0063 0.1786
Loa Loa (eye worm) subtilase 0.0286 0.032 0.0319
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0046 0.0023 0.003
Brugia malayi Furin-like cysteine rich region family protein 0.0385 0.0443 0.0442
Echinococcus multilocularis membrane bound transcription factor site 1 0.0286 0.032 0.0432
Onchocerca volvulus 0.0044 0.002 0.0293
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.013 0.0175
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0069 0.0051 0.0723
Schistosoma mansoni chromatin regulatory protein sir2 0.0048 0.0025 0.0031
Brugia malayi hypothetical protein 0.0035 0.0008 0.0007
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0046 0.0023 0.0027
Echinococcus granulosus protein will die slowly 0.0134 0.0131 0.0162
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0051 0.1399
Echinococcus granulosus fibrillin 1 0.0192 0.0203 0.0252
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0116 0.0109 0.0108
Mycobacterium leprae Possible secreted protease 0.0286 0.032 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0326 0.0369 0.0751
Onchocerca volvulus 0.0037 0.0011 0.0058
Schistosoma mansoni glutamate receptor NMDA 0.0259 0.0286 0.0356
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0286 0.032 0.0651
Toxoplasma gondii subtilisin SUB10 0.0286 0.032 1
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0003 0.0004
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0286 0.032 1
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.008 0.0065 0.0064
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.008 0.0065 0.1206
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0139 0.0137 0.0185
Schistosoma mansoni hypothetical protein 0.0057 0.0036 0.0045
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0139 0.0137 0.0169

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.