Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 1 | 1 |
Onchocerca volvulus | 0.0196 | 1 | 1 | |
Giardia lamblia | Aldose reductase | 0.0196 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0057 | 0.178 | 0.178 |
Echinococcus granulosus | hypothetical protein | 0.0196 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0139 | 0.6648 | 0.5922 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0196 | 1 | 1 |
Toxoplasma gondii | aldo-keto reductase | 0.0057 | 0.178 | 0.178 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0196 | 1 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0057 | 0.178 | 0.178 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0057 | 0.178 | 0.178 |
Schistosoma mansoni | aldo-keto reductase | 0.0196 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0196 | 1 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0057 | 0.178 | 0.178 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.2095 | 0.0383 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0196 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.2095 | 0.2095 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0196 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0196 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.2095 | 0.2095 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0057 | 0.178 | 0.178 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0196 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0196 | 1 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0062 | 0.2095 | 0.0383 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.2095 | 0.0383 |
Entamoeba histolytica | aldose reductase, putative | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0057 | 0.178 | 0.178 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.2095 | 0.2095 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0196 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0196 | 1 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0062 | 0.2095 | 0.0383 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0062 | 0.2095 | 0.0383 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0062 | 0.2095 | 0.0383 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0196 | 1 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0196 | 1 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0057 | 0.178 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0139 | 0.6648 | 0.5922 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0057 | 0.178 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0057 | 0.178 | 0.178 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0062 | 0.2095 | 0.0383 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0196 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0196 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0139 | 0.6648 | 0.5922 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 1 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0057 | 0.178 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0196 | 1 | 1 |
Onchocerca volvulus | 0.0196 | 1 | 1 | |
Onchocerca volvulus | 0.0196 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0196 | 1 | 1 |
Onchocerca volvulus | 0.0196 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0196 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0196 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0196 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0196 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0196 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0196 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0196 | 1 | 1 |
Onchocerca volvulus | 0.0196 | 1 | 1 | |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0057 | 0.178 | 0.178 |
Plasmodium vivax | aldehyde reductase, putative | 0.0057 | 0.178 | 1 |
Onchocerca volvulus | 0.0196 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.