Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | set domain proteins, putative | 0.0254 | 0.9995 | 0.5 |
Brugia malayi | hypothetical protein | 0.0043 | 0.1161 | 0.0587 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0043 | 0.1161 | 0.3638 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Brugia malayi | conserved hypotetical protein | 0.0043 | 0.1161 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Onchocerca volvulus | 0.0043 | 0.1161 | 0.0505 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0092 | 0.319 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0043 | 0.1161 | 0.0505 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0043 | 0.1161 | 0.3638 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0092 | 0.319 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.069 | 0.2163 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0043 | 0.1161 | 0.0587 |
Brugia malayi | nuclear receptor RXR | 0.0043 | 0.1161 | 0.0587 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0092 | 0.319 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0043 | 0.1161 | 0.3638 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.1161 | 0.3638 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0043 | 0.1161 | 0.3638 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0092 | 0.319 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0092 | 0.319 | 0.312 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0092 | 0.319 | 0.312 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0043 | 0.1161 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Brugia malayi | nuclear receptor NHR-67 | 0.0043 | 0.1161 | 0.0587 |
Brugia malayi | nuclear receptor NHR-88 | 0.0043 | 0.1161 | 0.0587 |
Schistosoma mansoni | coup transcription factor | 0.0092 | 0.319 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0048 | 0.1378 | 0.2751 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0092 | 0.319 | 0.312 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0092 | 0.319 | 1 |
Brugia malayi | tailless protein | 0.0043 | 0.1161 | 0.0587 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0092 | 0.319 | 0.2685 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0043 | 0.1161 | 0.3638 |
Brugia malayi | nuclear hormone receptor | 0.0043 | 0.1161 | 0.0587 |
Schistosoma mansoni | zinc finger protein | 0.0043 | 0.1161 | 0.1882 |
Brugia malayi | Pre-SET motif family protein | 0.0223 | 0.8702 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0965 | 0.1101 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0092 | 0.319 | 0.312 |
Brugia malayi | ecdysteroid receptor | 0.0092 | 0.319 | 0.312 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1378 | 0.1583 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0048 | 0.1378 | 0.1583 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0092 | 0.319 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0043 | 0.1161 | 0.3638 |
Schistosoma mansoni | nuclear receptor | 0.0043 | 0.1161 | 0.1882 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0043 | 0.1161 | 0.1334 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0043 | 0.1161 | 0.1882 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Onchocerca volvulus | 0.0043 | 0.1161 | 0.0505 | |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.069 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0092 | 0.319 | 0.3666 |
Brugia malayi | nuclear hormone receptor | 0.0092 | 0.319 | 0.312 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0092 | 0.319 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0043 | 0.1161 | 0.1882 |
Schistosoma mansoni | thyroid hormone receptor | 0.0092 | 0.319 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0092 | 0.319 | 0.312 |
Schistosoma mansoni | thyroid hormone receptor | 0.0092 | 0.319 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0048 | 0.1378 | 0.4319 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0965 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.069 | 0.0793 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0092 | 0.319 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0043 | 0.1161 | 0.0505 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0043 | 0.1161 | 0.0587 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0043 | 0.1161 | 0.0587 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0092 | 0.319 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0965 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0092 | 0.319 | 0.2685 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0043 | 0.1161 | 0.1334 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0092 | 0.319 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0048 | 0.1378 | 0.0859 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0092 | 0.319 | 0.3666 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0092 | 0.319 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0092 | 0.319 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.069 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0092 | 0.319 | 0.3666 |
Echinococcus granulosus | FTZ F1 alpha | 0.0092 | 0.319 | 1 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0079 | 0.2658 | 0.8332 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0043 | 0.1161 | 0.0587 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.069 | 0.2163 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0048 | 0.1378 | 0.0859 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0965 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0092 | 0.319 | 0.2685 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0092 | 0.319 | 0.312 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1378 | 0.1583 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0092 | 0.319 | 0.3666 |
Schistosoma mansoni | nuclear hormone receptor | 0.0043 | 0.1161 | 0.1882 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0043 | 0.1161 | 0.3638 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0641 | 0.2008 |
Brugia malayi | hypothetical protein | 0.0048 | 0.1378 | 0.0859 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0092 | 0.319 | 0.312 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0043 | 0.1161 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1378 | 0.1583 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Schistosoma mansoni | nuclear receptor | 0.0043 | 0.1161 | 0.1882 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0043 | 0.1161 | 0.1882 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0092 | 0.319 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0965 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0965 | 0.3026 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | DR-78 | 0.0043 | 0.1161 | 0.1334 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0092 | 0.319 | 0.312 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0048 | 0.1378 | 0.0859 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0092 | 0.319 | 0.312 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0092 | 0.319 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0092 | 0.319 | 1 |
Brugia malayi | steroid hormone receptor | 0.0092 | 0.319 | 0.312 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0092 | 0.319 | 0.312 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0048 | 0.1378 | 0.4319 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0079 | 0.2658 | 0.8332 |
Brugia malayi | hypothetical protein | 0.0043 | 0.1161 | 0.0587 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0092 | 0.319 | 0.312 |
Brugia malayi | nuclear receptor NHR-88 | 0.0092 | 0.319 | 0.312 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0043 | 0.1161 | 0.3638 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0092 | 0.319 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0092 | 0.319 | 0.312 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0092 | 0.319 | 0.312 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.1161 | 0.3638 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0043 | 0.1161 | 0.3638 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1378 | 0.1583 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0965 | 0.3026 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0043 | 0.1161 | 0.3638 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0092 | 0.319 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0092 | 0.319 | 0.312 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0965 | 0.5 |
Brugia malayi | ecdysone receptor | 0.0043 | 0.1161 | 0.0587 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0092 | 0.319 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1378 | 0.1583 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0048 | 0.1378 | 0.2751 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.319 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1161 | 0.1334 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0092 | 0.319 | 0.312 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0043 | 0.1161 | 0.1882 |
Schistosoma mansoni | nuclear hormone receptor | 0.0092 | 0.319 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0043 | 0.1161 | 0.1334 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0223 | 0.8702 | 1 |
Onchocerca volvulus | 0.0092 | 0.319 | 0.2685 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.069 | 0.2163 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0965 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0092 | 0.319 | 1 |
Brugia malayi | hypothetical protein | 0.0048 | 0.1378 | 0.0859 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0092 | 0.319 | 0.312 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0092 | 0.319 | 0.3666 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0092 | 0.319 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.