Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0165 | 0.3588 | 0.6981 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0165 | 0.3588 | 0.3564 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1996 | 0.2264 |
Echinococcus granulosus | protein kinase C gamma type | 0.0174 | 0.3894 | 0.3871 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1556 | 0.1755 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.8182 | 0.9411 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0213 | 0.5124 | 0.5106 |
Mycobacterium ulcerans | lysophospholipase | 0.007 | 0.0527 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.007 | 0.0527 | 1 |
Schistosoma mansoni | amidase | 0.0102 | 0.1556 | 0.2986 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6952 | 0.7989 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Plasmodium vivax | PST-A protein | 0.007 | 0.0527 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.007 | 0.0527 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.007 | 0.0527 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.007 | 0.0527 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.007 | 0.0527 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0069 | 0.0499 | 0.0463 |
Plasmodium falciparum | lysophospholipase, putative | 0.007 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.8692 | 1 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.007 | 0.0527 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.007 | 0.0527 | 0.5 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0174 | 0.3894 | 0.3871 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0102 | 0.1556 | 0.1524 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0102 | 0.1556 | 0.1524 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.007 | 0.0527 | 1 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0115 | 0.1996 | 0.1966 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.0527 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.007 | 0.0527 | 0.5 |
Echinococcus granulosus | protein kinase c iota type | 0.0093 | 0.1268 | 0.1235 |
Brugia malayi | Protein kinase c protein 2 | 0.016 | 0.3421 | 0.953 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.0527 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0102 | 0.1556 | 0.1524 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0115 | 0.1996 | 0.1966 |
Toxoplasma gondii | AGC kinase | 0.0054 | 0.0038 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.007 | 0.0527 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0165 | 0.3588 | 0.4103 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.007 | 0.0527 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.007 | 0.0527 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0102 | 0.1556 | 0.1524 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0102 | 0.1556 | 0.2986 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.007 | 0.0527 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0069 | 0.0499 | 0.9413 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0213 | 0.5124 | 0.5106 |
Leishmania major | monoglyceride lipase, putative | 0.007 | 0.0527 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.3227 | 0.3685 |
Echinococcus multilocularis | protein kinase c iota type | 0.0093 | 0.1268 | 0.1235 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0213 | 0.5124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6952 | 0.7989 |
Onchocerca volvulus | 0.027 | 0.6952 | 0.5 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0213 | 0.5124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6952 | 0.7989 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.007 | 0.0527 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0115 | 0.1996 | 0.1966 |
Brugia malayi | amidase | 0.0102 | 0.1556 | 0.4276 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0121 | 0.2191 | 0.2489 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0165 | 0.3588 | 0.3564 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Brugia malayi | protein kinase C II. | 0.0165 | 0.3588 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Echinococcus multilocularis | expressed protein | 0.0365 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0054 | 0.0038 | 0.0712 |
Schistosoma mansoni | atypical protein kinase C | 0.0093 | 0.1268 | 0.2419 |
Plasmodium falciparum | esterase, putative | 0.007 | 0.0527 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.007 | 0.0527 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0122 | 0.2201 | 0.2172 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.