TDR Targets

Basic information

Technical information

TDR Targets ID: 831334
Name: N-[2-(4-ethylpiperazine-1-carbonyl)pyridin-4- yl]-4-methylbenzenesulfonamide
MW: 388.484 | Formula: C19H24N4O3S
H donors: 1 H acceptors: 4 LogP: 1.71 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCN1CCN(CC1)C(=O)c1nccc(c1)NS(=O)(=O)c1ccc(cc1)C
InChi: 1S/C19H24N4O3S/c1-3-22-10-12-23(13-11-22)19(24)18-14-16(8-9-20-18)21-27(25,26)17-6-4-15(2)5-7-17/h4-9,14H,3,10-13H2,1-2H3,(H,20,21)
InChiKey: FTISTNJMDNBAKQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[2-(4-ethylpiperazine-1-carbonyl)-4-pyridyl]-4-methyl-benzenesulfonamide
N-[2-[(4-ethyl-1-piperazinyl)-oxomethyl]-4-pyridyl]-4-methylbenzenesulfonamide
N-[2-(4-ethylpiperazin-1-yl)carbonylpyridin-4-yl]-4-methyl-benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	aminoadipate-semialdehyde dehydrogenase	0.0081	0.0219	0.0489
Schistosoma mansoni	tar DNA-binding protein	0.0127	0.0375	0.0836
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0059	0.0145	0.0134
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0211	0.0656	1
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Brugia malayi	RNA recognition motif domain containing protein	0.0127	0.0375	0.0836
Mycobacterium ulcerans	4'-phosphopantetheinyl transferase	0.0023	0.0024	0.0013
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0211	0.0656	1
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0011	0.0024
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0019	0.0011	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0067	0.015
Onchocerca volvulus		0.0228	0.0715	1
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.009	0.0249	0.0555
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0108	0.024
Trichomonas vaginalis	spcc417.12 protein, putative	0.0228	0.0715	1
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0019	0.0011	0.0024
Schistosoma mansoni	aldehyde dehydrogenase	0.0059	0.0145	0.0323
Echinococcus granulosus	dna polymerase eta	0.0019	0.0011	0.0024
Echinococcus multilocularis	dna polymerase eta	0.0019	0.0011	0.0024
Brugia malayi	Carboxylesterase family protein	0.1351	0.4489	1
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0108	0.0097
Toxoplasma gondii	histone lysine-specific demethylase LSD1/BHC110/KDMA1A	0.0211	0.0656	1
Loa Loa (eye worm)	carboxylesterase	0.0228	0.0715	0.1593
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0219	0.0489
Loa Loa (eye worm)	hypothetical protein	0.1351	0.4489	1
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0211	0.0656	1
Mycobacterium tuberculosis	Carboxylesterase LipT	0.0228	0.0715	0.0759
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Schistosoma mansoni	acetylcholinesterase	0.0228	0.0715	0.1593
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0019	0.0011	0.0024
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.009	0.0249	0.0555
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0048	0.0108	0.0097
Mycobacterium ulcerans	oxidoreductase	0.0211	0.0656	0.0646
Echinococcus multilocularis	tar DNA binding protein	0.0127	0.0375	0.0836
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0228	0.0715	0.1593
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0059	0.0145	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0048	0.0108	0.0105
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0211	0.0656	1
Onchocerca volvulus		0.0228	0.0715	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0036	0.0067	0.0057
Brugia malayi	Muscleblind-like protein	0.03	0.0956	0.213
Echinococcus granulosus	geminin	0.0167	0.051	0.1136
Schistosoma mansoni	tar DNA-binding protein	0.0127	0.0375	0.0836
Loa Loa (eye worm)	hypothetical protein	0.03	0.0956	0.213
Toxoplasma gondii	aldehyde dehydrogenase	0.0059	0.0145	0.1913
Schistosoma mansoni	gliotactin	0.0228	0.0715	0.1593
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0048	0.0108	0.0105
Entamoeba histolytica	hypothetical protein	0.0035	0.0065	0.5546
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0113	0.0252
Brugia malayi	Carboxylesterase family protein	0.0228	0.0715	0.1593
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0211	0.0656	0.146
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0108	0.024
Onchocerca volvulus		0.0081	0.0219	0.1838
Brugia malayi	hypothetical protein	0.0211	0.0656	0.146
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0113	0.0252
Brugia malayi	Carboxylesterase family protein	0.1351	0.4489	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0061	0.0054
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.0228	0.0715	1
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.0108	1
Toxoplasma gondii	histone lysine-specific demethylase	0.0211	0.0656	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0061	0.0135
Brugia malayi	Carboxylesterase family protein	0.0228	0.0715	0.1593
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0228	0.0715	0.0759
Loa Loa (eye worm)	carboxylesterase	0.1351	0.4489	1
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0067	0.015
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0065	0.0144
Schistosoma mansoni	hypothetical protein	0.0035	0.0065	0.0144
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0048	0.0108	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0108	0.024
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.1351	0.4489	1
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0048	0.0108	0.0097
Mycobacterium ulcerans	protoporphyrinogen oxidase	0.0211	0.0656	0.0646
Echinococcus multilocularis		0.0211	0.0656	0.146
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0108	0.1504
Echinococcus granulosus	para nitrobenzyl esterase	0.0228	0.0715	0.1593
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0211	0.0656	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.0249	0.0555
Schistosoma mansoni	BC026374 protein (S09 family)	0.0228	0.0715	0.1593
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0228	0.0715	0.0759
Entamoeba histolytica	hypothetical protein	0.0035	0.0065	0.5546
Mycobacterium ulcerans	dehydrogenase	0.0211	0.0656	0.0646
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0011	0.0024
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0059	0.0145	0.0145
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0061	0.0054
Echinococcus multilocularis	neuroligin	0.0228	0.0715	0.1593
Echinococcus granulosus	tar DNA binding protein	0.0127	0.0375	0.0836
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0113	0.0252
Echinococcus granulosus	acetylcholinesterase	0.1351	0.4489	1
Brugia malayi	amine oxidase, flavin-containing family protein	0.0211	0.0656	0.146
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0211	0.0656	0.0695
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0108	0.1504
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0211	0.0656	0.146
Schistosoma mansoni	hypothetical protein	0.0167	0.051	0.1136
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.009	0.0249	0.0555
Loa Loa (eye worm)	carboxylesterase	0.0228	0.0715	0.1593
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0228	0.0715	0.1593
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0228	0.0715	0.1593
Schistosoma mansoni	amine oxidase	0.0211	0.0656	0.146
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.009	0.0249	0.0555
Echinococcus multilocularis	L aminoadipate semialdehyde	0.0081	0.0219	0.0489
Plasmodium vivax	hypothetical protein, conserved	0.0211	0.0656	1
Plasmodium vivax	acyl-CoA synthetase, putative	0.0036	0.0067	0.0684
Onchocerca volvulus		0.0228	0.0715	1
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Schistosoma mansoni	hypothetical protein	0.0167	0.051	0.1136
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0228	0.0715	0.1593
Entamoeba histolytica	hypothetical protein	0.0035	0.0065	0.5546
Brugia malayi	SWIRM domain containing protein	0.0211	0.0656	0.146
Mycobacterium ulcerans	monoamine oxidase	0.0211	0.0656	0.0646
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.0108	0.1325
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.0249	0.0555
Brugia malayi	hypothetical protein	0.0035	0.0065	0.0144
Echinococcus granulosus	carboxylesterase 5A	0.1351	0.4489	1
Echinococcus multilocularis	acetylcholinesterase	0.1351	0.4489	1
Leishmania major	UDP-galactopyranose mutase	0.0211	0.0656	1
Echinococcus granulosus	neuroligin	0.0228	0.0715	0.1593
Echinococcus multilocularis	muscleblind protein	0.03	0.0956	0.213
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0127	0.0375	0.0836
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0059	0.0145	0.2081
Brugia malayi	Carboxylesterase family protein	0.0228	0.0715	0.1593
Wolbachia endosymbiont of Brugia malayi	4'-phosphopantetheinyl transferase	0.0023	0.0024	0.5
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.009	0.0249	0.0555
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0061	0.0054
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0108	0.0097
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.299	1	1
Loa Loa (eye worm)	transcription factor SMAD2	0.0122	0.0357	0.0796
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0211	0.0656	0.146
Mycobacterium leprae	PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO)	0.0211	0.0656	1
Schistosoma mansoni	hypothetical protein	0.0034	0.0061	0.0135
Onchocerca volvulus		0.0228	0.0715	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0122	0.0357	0.0796
Echinococcus multilocularis	carboxylesterase 5A	0.1351	0.4489	1
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0059	0.0145	0.0134
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.009	0.0249	0.0555
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0036	0.0067	0.0061
Echinococcus granulosus	BC026374 protein S09 family	0.0228	0.0715	0.1593
Mycobacterium tuberculosis	Possible oxidoreductase	0.0211	0.0656	0.0695
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0059	0.0145	0.0323
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0061	0.0054
Schistosoma mansoni	tar DNA-binding protein	0.0127	0.0375	0.0836
Schistosoma mansoni	amine oxidase	0.0211	0.0656	0.146
Mycobacterium ulcerans	carboxylesterase, LipT	0.0228	0.0715	0.0705
Mycobacterium tuberculosis	Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO)	0.2779	0.9292	1
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.0108	0.1325
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0067	0.015
Plasmodium falciparum	protoporphyrinogen oxidase	0.0211	0.0656	1
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0019	0.0011	0.0024
Schistosoma mansoni	aldehyde dehydrogenase	0.0059	0.0145	0.0323
Echinococcus multilocularis	geminin	0.0167	0.051	0.1136
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0011	0.0024
Echinococcus granulosus	L aminoadipate semialdehyde	0.0081	0.0219	0.0489
Echinococcus granulosus	muscleblind protein	0.03	0.0956	0.213
Mycobacterium ulcerans	phosphopantetheinyl transferase, PptII	0.0023	0.0024	0.0013
Trypanosoma brucei	hypothetical protein, conserved	0.0023	0.0024	1
Echinococcus multilocularis	dna polymerase kappa	0.0019	0.0011	0.0024
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0108	0.024
Brugia malayi	Carboxylesterase family protein	0.0228	0.0715	0.1593
Giardia lamblia	DINP protein human, muc B family	0.0019	0.0011	0.5
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0113	0.0252
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Mycobacterium tuberculosis	holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie	0.0023	0.0024	0.0014
Brugia malayi	RNA binding protein	0.0127	0.0375	0.0836
Echinococcus multilocularis	acetylcholinesterase	0.1351	0.4489	1
Entamoeba histolytica	hypothetical protein	0.0023	0.0024	0.1376
Entamoeba histolytica	hypothetical protein	0.0035	0.0065	0.5546
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0108	0.024
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0228	0.0715	0.1593
Onchocerca volvulus		0.0211	0.0656	0.9021
Entamoeba histolytica	acyl-coA synthetase, putative	0.0048	0.0108	1
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0065	0.0144
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.0249	0.0555
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0228	0.0715	0.1593
Brugia malayi	TAR-binding protein	0.0127	0.0375	0.0836
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0211	0.0656	1
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0211	0.0656	0.146
Echinococcus granulosus	dna polymerase kappa	0.0019	0.0011	0.0024
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0065	0.0144
Loa Loa (eye worm)	hypothetical protein	0.03	0.0956	0.213
Loa Loa (eye worm)	acetylcholinesterase 1	0.1351	0.4489	1
Schistosoma mansoni	DNA polymerase eta	0.0019	0.0011	0.0024
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0019	0.0011	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0061	0.0135
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0067	0.015
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0108	0.1504
Echinococcus multilocularis	muscleblind protein 1	0.03	0.0956	0.213
Brugia malayi	hypothetical protein	0.0228	0.0715	0.1593
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Brugia malayi	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	0.0081	0.0219	0.0489
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0048	0.0108	0.0097
Schistosoma mansoni	tar DNA-binding protein	0.0127	0.0375	0.0836
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0656	0.146
Plasmodium vivax	hypothetical protein, conserved	0.0211	0.0656	1
Loa Loa (eye worm)	TAR-binding protein	0.0127	0.0375	0.0836
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0228	0.0715	0.1593
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0211	0.0656	0.146
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.0108	1
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0059	0.0145	0.0134
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0108	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0067	0.015
Treponema pallidum	4'-phosphopantetheinyl transferase	0.0023	0.0024	0.5
Mycobacterium ulcerans	hypothetical protein	0.0048	0.0108	0.0097
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0211	0.0656	0.146
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0715	0.1593
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0036	0.0067	0.0684
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0108	0.024
Schistosoma mansoni	tar DNA-binding protein	0.0127	0.0375	0.0836
Leishmania major	phosphopantetheinyl transferase-like protein	0.0023	0.0024	0.0207
Plasmodium falciparum	acyl-CoA synthetase	0.0036	0.0067	0.0684
Loa Loa (eye worm)	hypothetical protein	0.1351	0.4489	1
Loa Loa (eye worm)	RNA binding protein	0.0127	0.0375	0.0836
Echinococcus multilocularis	para nitrobenzyl esterase	0.0228	0.0715	0.1593
Brugia malayi	MH2 domain containing protein	0.0122	0.0357	0.0796
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0211	0.0656	1
Onchocerca volvulus		0.0228	0.0715	1
Echinococcus granulosus	acetylcholinesterase	0.1351	0.4489	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 831334