Detailed information for compound 831654

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.757 | Formula: C15H14ClN5O2
  • H donors: 2 H acceptors: 5 LogP: 2.17 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)Cl)CCc1c(C)nc2n(c1O)ncn2
  • InChi: 1S/C15H14ClN5O2/c1-9-12(14(23)21-15(19-9)17-8-18-21)6-7-13(22)20-11-4-2-10(16)3-5-11/h2-5,8,23H,6-7H2,1H3,(H,20,22)
  • InChiKey: ZFCBWUORAKPNQC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0739
Onchocerca volvulus 0.0023 0.0088 0.0506
Schistosoma mansoni hypothetical protein 0.0327 0.1841 0.1841
Echinococcus multilocularis acetylcholinesterase 0.1745 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0023 0.0088 0.0083
Mycobacterium ulcerans hypothetical protein 0.0026 0.0106 0.0612
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Echinococcus granulosus carboxylesterase 5A 0.1745 1 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.004 0.0184 0.0179
Echinococcus multilocularis GPCR, family 2 0.0034 0.0154 0.0149
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0295 0.1653 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0005 0.0005
Echinococcus granulosus geminin 0.0363 0.2045 0.2041
Toxoplasma gondii CAAX amino terminal protease family protein 0.0026 0.0106 0.5132
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0005 0.0005
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0009 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.0295 0.1653 0.1649
Trypanosoma brucei CAAX amino terminal protease, putative 0.0126 0.0683 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0126 0.0126
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0008 0.0274
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0054 0.0268 0.0268
Brugia malayi Carboxylesterase family protein 0.0295 0.1653 0.1653
Onchocerca volvulus 0.0054 0.0268 0.1597
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0033 0.0033
Echinococcus multilocularis peregrin 0.0023 0.009 0.0085
Onchocerca volvulus 0.0295 0.1653 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0023 0.009 0.0085
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0295 0.1653 0.1649
Loa Loa (eye worm) hypothetical protein 0.0065 0.033 0.0325
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0005 0.0005
Echinococcus granulosus jumonji domain containing protein 0.0032 0.0143 0.0138
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0005 0.0005
Brugia malayi ecdysteroid receptor 0.0009 0.0005 0.0005
Toxoplasma gondii hypothetical protein 0.0026 0.0106 0.5132
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0009 0.0005 0.0005
Schistosoma mansoni gliotactin 0.0295 0.1653 0.1653
Echinococcus granulosus cpg binding protein 0.0024 0.0096 0.0091
Schistosoma mansoni cpg binding protein 0.0024 0.0096 0.0096
Echinococcus multilocularis lysine specific demethylase 5A 0.0028 0.0119 0.0114
Echinococcus granulosus BC026374 protein S09 family 0.0295 0.1653 0.1649
Brugia malayi Thioredoxin reductase 0.0025 0.0098 0.0098
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0015 0.0044 0.3826
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0009 0.0005 0.0078
Brugia malayi RNA binding protein 0.0053 0.0263 0.0263
Echinococcus granulosus tar DNA binding protein 0.0053 0.0263 0.0258
Loa Loa (eye worm) carboxylesterase 0.0295 0.1653 0.1649
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0044 0.3826
Mycobacterium tuberculosis Carboxylesterase LipT 0.0295 0.1653 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0015 0.0044 0.2122
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0233 0.0228
Mycobacterium tuberculosis Probable dehydrogenase 0.0056 0.028 0.1667
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.004 0.004
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0126 0.0683 0.0683
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.033 0.033
Brugia malayi TAR-binding protein 0.0053 0.0263 0.0263
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0154 0.0149
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0023 0.009 0.009
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0015 0.0044 0.0234
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0126 0.0683 1
Schistosoma mansoni cpg binding protein 0.0023 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0034 0.0154 0.0154
Toxoplasma gondii NADPH-glutathione reductase 0.0009 0.0005 0.0257
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.004 0.0184 0.1085
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0295 0.1653 0.1649
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0015 0.0044 0.2122
Giardia lamblia PHD finger protein 15 0.0023 0.009 0.1256
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0009 0.0005 0.0078
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0126 0.0126
Brugia malayi steroid hormone receptor 0.0009 0.0005 0.0005
Leishmania major phosphopantetheinyl transferase-like protein 0.0015 0.0044 0.0569
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0023 0.0091 0.0086
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0894 0.5102 0.5099
Schistosoma mansoni aldehyde dehydrogenase 0.004 0.0184 0.0184
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0054 0.0268 0.0268
Echinococcus granulosus neuroligin 0.0295 0.1653 0.1649
Schistosoma mansoni tar DNA-binding protein 0.0053 0.0263 0.0263
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0126 0.0683 0.0683
Echinococcus multilocularis neuroligin 0.0295 0.1653 0.1649
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0063 0.0316 0.1886
Schistosoma mansoni hypothetical protein 0.0023 0.0091 0.0091
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0295 0.1653 1
Schistosoma mansoni hypothetical protein 0.0023 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.1745 1 1
Plasmodium vivax glutathione reductase, putative 0.0025 0.0098 0.9204
Schistosoma mansoni hypothetical protein 0.0034 0.0154 0.0154
Brugia malayi hypothetical protein 0.0023 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Loa Loa (eye worm) hypothetical protein 0.0126 0.0683 0.0678
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0076 0.0396 0.0391
Echinococcus multilocularis geminin 0.0363 0.2045 0.2041
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0009 0.0007 0.0002
Echinococcus granulosus PHD finger protein rhinoceros 0.0023 0.009 0.0085
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0056 0.028 0.1667
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0154 0.0149
Toxoplasma gondii PHD-finger domain-containing protein 0.0023 0.009 0.4373
Echinococcus multilocularis L aminoadipate semialdehyde 0.0054 0.0268 0.0263
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0237 0.0237
Onchocerca volvulus 0.0065 0.033 0.1971
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0005 0.0005
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0053 0.0263 0.0263
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0076 0.0396 0.0391
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.004 0.0184 0.0179
Brugia malayi Carboxylesterase family protein 0.0295 0.1653 0.1653
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0106 0.0612
Echinococcus multilocularis BC026374 protein (S09 family) 0.0295 0.1653 0.1649
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0015 0.0044 0.3826
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0005 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0044 0.0642
Mycobacterium ulcerans carboxylesterase, LipT 0.0295 0.1653 1
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0126 0.0683 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0056 0.028 0.1667
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0583 0.0583
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1745 1 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0295 0.1653 0.1649
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0005 0.0005
Onchocerca volvulus Alhambra homolog 0.0023 0.009 0.0518
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.0126 0.0121
Brugia malayi jmjC domain containing protein 0.003 0.0126 0.0126
Mycobacterium tuberculosis Probable oxidoreductase 0.0063 0.0316 0.1886
Echinococcus granulosus acetylcholinesterase 0.1745 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0154 0.0149
Echinococcus multilocularis cpg binding protein 0.0024 0.0096 0.0091
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0025 0.0098 0.1369
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0076 0.0396 0.0396
Schistosoma mansoni tar DNA-binding protein 0.0053 0.0263 0.0263
Toxoplasma gondii PHD-finger domain-containing protein 0.0023 0.009 0.4373
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.0295 0.1653 0.1653
Schistosoma mansoni neuroligin 3 (S09 family) 0.0295 0.1653 0.1653
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.0184 0.1085
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.004 0.0184 0.2637
Loa Loa (eye worm) TAR-binding protein 0.0053 0.0263 0.0258
Onchocerca volvulus 0.0295 0.1653 1
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0384 0.0384
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0005 0.0078
Entamoeba histolytica CAAX prenyl protease family 0.0126 0.0683 1
Schistosoma mansoni hypothetical protein 0.0074 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.004 0.0186 0.0181
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0005 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0025 0.01 0.0095
Entamoeba histolytica CAAX amino terminal protease family 0.0026 0.0106 0.0974
Loa Loa (eye worm) glutathione reductase 0.0025 0.0098 0.0093
Plasmodium vivax thioredoxin reductase, putative 0.0025 0.0098 0.9204
Loa Loa (eye worm) carboxylesterase 0.1745 1 1
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0026 0.0106 0.0612
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.0184 0.1085
Loa Loa (eye worm) thioredoxin reductase 0.0025 0.0098 0.0093
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0126 0.0683 1
Mycobacterium tuberculosis Probable integral membrane protein 0.0026 0.0106 0.0612
Onchocerca volvulus 0.0061 0.0306 0.1824
Schistosoma mansoni acetylcholinesterase 0.0295 0.1653 0.1653
Echinococcus granulosus acetylcholinesterase 0.1745 1 1
Toxoplasma gondii hypothetical protein 0.0026 0.0106 0.5132
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0583 0.0578
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0085
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0044 0.3826
Onchocerca volvulus 0.0295 0.1653 1
Entamoeba histolytica CAAX amino terminal protease family 0.0026 0.0106 0.0974
Echinococcus granulosus para nitrobenzyl esterase 0.0295 0.1653 0.1649
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0023 0.0091 0.0086
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0015 0.0044 0.0234
Echinococcus multilocularis carboxylesterase 5A 0.1745 1 1
Echinococcus multilocularis CAAX prenyl protease 2 0.0126 0.0683 0.0678
Schistosoma mansoni hypothetical protein 0.0034 0.0154 0.0154
Schistosoma mansoni cpg binding protein 0.0024 0.0096 0.0096
Echinococcus granulosus thioredoxin glutathione reductase 0.0025 0.01 0.0095
Schistosoma mansoni hypothetical protein 0.0363 0.2045 0.2045
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0056 0.028 0.1667
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0063 0.0316 0.1886
Echinococcus multilocularis tar DNA binding protein 0.0053 0.0263 0.0258
Loa Loa (eye worm) hypothetical protein 0.0034 0.0154 0.0149
Plasmodium falciparum protease, putative 0.0026 0.0106 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0005 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0023 0.009 0.8442
Echinococcus multilocularis dnaJ subfamily B 0.0327 0.1841 0.1836
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.0184 0.1085
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0053 0.0263 0.0258
Echinococcus granulosus L aminoadipate semialdehyde 0.0054 0.0268 0.0263
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0005 0.0005
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0009 0.0008 0.0274
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0739
Brugia malayi PHD-finger family protein 0.0009 0.0008 0.0008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0154 0.0154
Toxoplasma gondii aldehyde dehydrogenase 0.004 0.0184 0.89
Loa Loa (eye worm) hypothetical protein 0.0054 0.0268 0.0263
Plasmodium falciparum glutathione reductase 0.0025 0.0098 0.9204
Brugia malayi nuclear receptor NHR-88 0.0009 0.0005 0.0005
Echinococcus granulosus dnaJ subfamily B 0.0327 0.1841 0.1836
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0009 0.0005 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.1745 1 1
Plasmodium falciparum phd finger protein, putative 0.0023 0.009 0.8442
Brugia malayi RNA recognition motif domain containing protein 0.0053 0.0263 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0005 0.0005
Onchocerca volvulus 0.0295 0.1653 1
Toxoplasma gondii thioredoxin reductase 0.0025 0.0098 0.4744
Brugia malayi glutathione reductase 0.0025 0.0098 0.0098
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0015 0.0044 0.0234
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0009 0.0007 0.0002
Onchocerca volvulus 0.0295 0.1653 1
Plasmodium falciparum thioredoxin reductase 0.0025 0.0098 0.9204
Loa Loa (eye worm) RNA binding protein 0.0053 0.0263 0.0258
Mycobacterium ulcerans hypothetical protein 0.0026 0.0106 0.0612
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0053 0.0263 0.0263
Echinococcus granulosus CAAX prenyl protease 2 0.0126 0.0683 0.0678
Giardia lamblia Hypothetical protein 0.0126 0.0683 1
Schistosoma mansoni aldehyde dehydrogenase 0.004 0.0184 0.0184
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0295 0.1653 0.1653
Schistosoma mansoni coup transcription factor 0.0009 0.0005 0.0005
Mycobacterium ulcerans integral membrane protein 0.0026 0.0106 0.0612
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.009 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0053 0.0263 0.0263
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0295 0.1653 0.1653
Brugia malayi PHD-finger family protein 0.0023 0.009 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0126 0.0121
Brugia malayi nuclear hormone receptor 0.0009 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0074 0.0384 0.0379
Loa Loa (eye worm) hypothetical protein 0.0109 0.0583 0.0578
Loa Loa (eye worm) acetylcholinesterase 1 0.1745 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0025 0.0098 0.0563
Schistosoma mansoni transcription factor LCR-F1 0.0023 0.0091 0.0091
Brugia malayi Carboxylesterase family protein 0.0295 0.1653 0.1653
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Echinococcus multilocularis acetylcholinesterase 0.1745 1 1
Brugia malayi hypothetical protein 0.0295 0.1653 0.1653
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0005 0.0078
Plasmodium vivax protease, putative 0.0026 0.0106 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0295 0.1653 1
Schistosoma mansoni hypothetical protein 0.0034 0.0154 0.0154
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0739
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0154 0.0149
Schistosoma mansoni hypothetical protein 0.0363 0.2045 0.2045
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0056 0.028 0.1667
Leishmania major trypanothione reductase 0.0025 0.0098 0.1369
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0005 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0154 0.0149
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0063 0.0316 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0739
Chlamydia trachomatis hypothetical protein 0.0026 0.0106 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0583 0.0583
Echinococcus granulosus GPCR family 2 0.0034 0.0154 0.0149
Trypanosoma brucei trypanothione reductase 0.0025 0.0098 0.1436
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0026 0.0106 0.0612
Brugia malayi CAAX amino terminal protease family protein 0.0126 0.0683 0.0683
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0005 0.0005
Treponema pallidum hypothetical protein 0.0026 0.0106 1
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0005 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0295 0.1653 0.1653
Brugia malayi Bromodomain containing protein 0.0023 0.009 0.009
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0306 0.0306
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0005 0.0005
Brugia malayi CXXC zinc finger family protein 0.0023 0.0088 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0005 0.0005
Brugia malayi Trypsin family protein 0.0065 0.033 0.033
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0056 0.028 0.8672
Echinococcus multilocularis jumonji domain containing protein 0.0032 0.0143 0.0138
Loa Loa (eye worm) hypothetical protein 0.0295 0.1653 0.1649
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0126 0.0683 0.4114
Mycobacterium tuberculosis Probable reductase 0.0056 0.028 0.1667
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0005 0.0005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.033 0.033
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0015 0.0044 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.033 0.0325
Echinococcus granulosus peregrin 0.0023 0.009 0.0085
Loa Loa (eye worm) hypothetical protein 0.1745 1 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0295 0.1653 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0044 0.0207 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0295 0.1653 0.1653
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0005 0.0005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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