Detailed information for compound 831733

Basic information

Technical information
  • TDR Targets ID: 831733
  • Name: N-butan-2-yl-3-(5,7-dimethyl-[1,2,4]triazolo[ 1,5-a]pyrimidin-6-yl)propanamide
  • MW: 275.349 | Formula: C14H21N5O
  • H donors: 1 H acceptors: 4 LogP: 1.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(NC(=O)CCc1c(C)nc2n(c1C)ncn2)C
  • InChi: 1S/C14H21N5O/c1-5-9(2)17-13(20)7-6-12-10(3)18-14-15-8-16-19(14)11(12)4/h8-9H,5-7H2,1-4H3,(H,17,20)
  • InChiKey: OSTVTDYDIGEPCD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-sec-butyl-propanamide
  • 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-sec-butylpropanamide
  • 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-sec-butyl-propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1694 0.2295
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0082 0.068 0.0758
Echinococcus multilocularis natriuretic peptide receptor 1 0.0096 0.0991 0.1343
Leishmania major protein kinase, putative 0.0096 0.0991 0.5852
Echinococcus multilocularis tyrosine protein kinase Blk 0.0178 0.2763 0.3743
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0082 0.068 0.068
Loa Loa (eye worm) TK/ROR protein kinase 0.0102 0.1121 0.1249
Echinococcus granulosus rho-associated protein kinase 1 0.0148 0.2125 0.2125
Echinococcus granulosus 5'partial|3'partial|mitogen activated protein kinase kinase kinase 0.0091 0.0882 0.0882
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica protein kinase, putative 0.0084 0.0737 0.2667
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0181 0.2843 0.2843
Schistosoma mansoni tensin 0.0082 0.068 0.0921
Onchocerca volvulus 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase domain containing protein 0.0099 0.1048 0.3793
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0096 0.0991 0.1105
Brugia malayi Protein kinase domain containing protein 0.0178 0.2763 0.308
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/FAK protein kinase 0.0351 0.6531 0.7279
Echinococcus granulosus receptor type guanylyl cyclase 0.0096 0.0991 0.0991
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0091 0.0882 0.1194
Schistosoma mansoni serine/threonine RGC 0.0096 0.0991 0.1343
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0178 0.2763 0.2763
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0096 0.0991 0.1105
Echinococcus multilocularis SHC transforming protein 3 0.0082 0.068 0.0921
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Echinococcus multilocularis activated cdc42 kinase 1 0.0096 0.0991 0.1343
Schistosoma mansoni tensin-related 0.0082 0.068 0.0921
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0096 0.0991 0.0991
Plasmodium falciparum protein kinase, putative 0.0096 0.0991 0.9458
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Echinococcus multilocularis tensin 0.0082 0.068 0.0921
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0096 0.0991 0.1105
Echinococcus granulosus epidermal growth factor receptor 0.0096 0.0991 0.0991
Plasmodium vivax protein kinase, putative 0.0096 0.0991 1
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus granulosus 3'partial|mitogen activated protein kinase kinase kinase 0.0091 0.0882 0.0882
Brugia malayi Protein kinase domain containing protein 0.0178 0.2763 0.308
Brugia malayi Raf kinase 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine kinase 0.0113 0.1368 0.1853
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0082 0.068 0.0921
Echinococcus granulosus fibroblast growth factor receptor 4 0.0195 0.3136 0.3136
Schistosoma mansoni tensin-related 0.0082 0.068 0.0921
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosin kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Protein kinase domain containing protein 0.0464 0.8972 1
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK protein kinase 0.0178 0.2763 0.308
Entamoeba histolytica tyrosin kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Guanylyl cyclase protein 23 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0096 0.0991 0.1343
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0082 0.068 0.0758
Trypanosoma cruzi protein kinase, putative 0.0096 0.0991 0.5852
Trypanosoma brucei Pseudokinase, putative 0.0096 0.0991 0.5852
Onchocerca volvulus Tyrosine kinase homolog 0.0275 0.4874 0.5433
Plasmodium vivax tyrosine kinase-like protein, putative 0.0096 0.0991 1
Brugia malayi Protein kinase domain containing protein 0.0178 0.2763 0.308
Echinococcus granulosus suppressor of cytokine signaling 6 0.0082 0.068 0.068
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus tyrosine kinase 0.0178 0.2763 0.2763
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Brugia malayi SRC-1 0.0181 0.2843 0.3169
Schistosoma mansoni tensin 0.0082 0.068 0.0921
Brugia malayi Variant SH3 domain containing protein 0.0085 0.076 0.0847
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0082 0.068 0.068
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0084 0.0737 0.2667
Giardia lamblia Kinase 0.0096 0.0991 1
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0181 0.2843 0.2843
Onchocerca volvulus 0.0096 0.0991 0.1105
Schistosoma mansoni ephrin receptor 0.0096 0.0991 0.1343
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK/EGFR protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0181 0.2843 0.3852
Echinococcus granulosus tyrosine protein kinase csk 0.0096 0.0991 0.0991
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1694 0.2295
Loa Loa (eye worm) TK/ACK protein kinase 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0178 0.2763 0.308
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0178 0.2763 1
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0096 0.0991 0.1105
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0082 0.068 0.0921
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Sex muscle abnormal protein 5 0.0085 0.076 0.0847
Echinococcus granulosus activated cdc42 kinase 1 0.0096 0.0991 0.0991
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0178 0.2763 0.2763
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0128 0.1694 1
Toxoplasma gondii protein kinase 0.0096 0.0991 0.9458
Onchocerca volvulus 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Schistosoma mansoni tyrosine kinase 0.0348 0.6466 0.8759
Loa Loa (eye worm) TK protein kinase 0.0201 0.3265 0.3639
Echinococcus granulosus activated cdc42 kinase 1 0.0096 0.0991 0.0991
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus multilocularis insulin receptor 0.0096 0.0991 0.1343
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.2125 0.2878
Onchocerca volvulus 0.0082 0.068 0.0758
Loa Loa (eye worm) TK/ALK protein kinase 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi SH2 domain containing protein 0.0178 0.2763 0.308
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0085 0.076 0.1029
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0181 0.2843 0.3852
Schistosoma mansoni suppressor of cytokine signaling 0.0082 0.068 0.0921
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0096 0.0991 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0308 0.5583 0.6223
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis N chimaerin 0.0082 0.068 0.0921
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis signal transduction protein lnk realted 0.0082 0.068 0.0921
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Brugia malayi SH2 domain containing protein 0.0178 0.2763 0.308
Loa Loa (eye worm) TK/EPH protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0091 0.0882 0.1194
Entamoeba histolytica cysteine surface protein, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0991 0.1105
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0096 0.0991 0.0991
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0178 0.2763 0.3743
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.068 0.0921
Echinococcus granulosus retinal guanylyl cyclase 2 0.0096 0.0991 0.0991
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Onchocerca volvulus 0.0178 0.2763 0.308
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus suppressor of cytokine signaling 7 0.0082 0.068 0.068
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0096 0.0991 1
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0178 0.2763 0.308
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Brugia malayi C-terminal src kinase protein 1 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Onchocerca volvulus 0.0082 0.068 0.0758
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi hypothetical protein 0.0178 0.2763 0.308
Loa Loa (eye worm) TK/RYK protein kinase 0.0096 0.0991 0.1105
Echinococcus granulosus tensin 0.0082 0.068 0.068
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0096 0.0991 0.1343
Brugia malayi Protein kinase domain containing protein 0.0178 0.2763 0.308
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0181 0.2843 0.3852
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Entamoeba histolytica receptor protein kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0085 0.076 0.0847
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0096 0.0991 0.1343
Brugia malayi ephrin receptor 1 precursor 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/CSK protein kinase 0.0096 0.0991 0.1105
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.01 0.1071 0.1451
Echinococcus granulosus SH2 domain containing protein 7 0.0082 0.068 0.068
Echinococcus granulosus tyrosine protein kinase Src42A 0.0082 0.068 0.068
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0085 0.076 0.076
Schistosoma mansoni tyrosine kinase 0.0181 0.2843 0.3852
Echinococcus granulosus mitogen activated protein kinase 14 0.0128 0.1694 0.1694
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0096 0.0991 0.1105
Plasmodium vivax tyrosine kinase-like protein, putative 0.0096 0.0991 1
Entamoeba histolytica receptor protein kinase, putative 0.0096 0.0991 0.3587
Echinococcus multilocularis protein KINase family member (kin 25) 0.0096 0.0991 0.1343
Loa Loa (eye worm) SH2 domain-containing protein 0.0082 0.068 0.0758
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0184 0.2908 0.2908
Loa Loa (eye worm) SH2 domain-containing protein 0.0082 0.068 0.0758
Brugia malayi STAT protein, DNA binding domain containing protein 0.0082 0.068 0.0758
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0096 0.0991 0.0991
Echinococcus granulosus hypothetical protein 0.0082 0.068 0.068
Giardia lamblia Protein 21.1 0.0096 0.0991 1
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus retinal guanylyl cyclase 2 0.0096 0.0991 0.0991
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Brugia malayi Protein kinase domain containing protein 0.0178 0.2763 0.308
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 7 0.0091 0.0882 0.1194
Schistosoma mansoni SH2A 0.0082 0.068 0.0921
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0096 0.0991 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0181 0.2843 0.3852
Echinococcus multilocularis receptor type guanylyl cyclase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Brugia malayi Tyrosine-protein kinase PR2 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0391 0.7382 1
Giardia lamblia Kinase, NEK 0.0096 0.0991 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0096 0.0991 0.1343
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Echinococcus granulosus tyrosine kinase 0.0178 0.2763 0.2763
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0096 0.0991 0.0991
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0178 0.2763 0.3743
Brugia malayi bone morphogenetic protein type 1 receptor 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0308 0.5583 0.6223
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0099 0.1048 0.1048
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0082 0.068 0.0758
Schistosoma mansoni tensin 0.0082 0.068 0.0921
Onchocerca volvulus 0.0082 0.068 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Echinococcus multilocularis tyrosine protein kinase 0.0096 0.0991 0.1343
Loa Loa (eye worm) STAT protein 0.0082 0.068 0.0758
Brugia malayi P38 map kinase family protein 2 0.0128 0.1694 0.1888
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0128 0.1694 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Schistosoma mansoni tyrosine kinase 0.0181 0.2843 0.3852
Echinococcus multilocularis epidermal growth factor receptor 0.0096 0.0991 0.1343
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Onchocerca volvulus 0.0464 0.8972 1
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1694 0.2295
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus multilocularis FL cytokine receptor 0.0096 0.0991 0.1343
Loa Loa (eye worm) TK/Met protein kinase 0.0096 0.0991 0.1105
Echinococcus granulosus tyrosine protein kinase 0.0096 0.0991 0.0991
Schistosoma mansoni tyrosine protein kinase 0.0096 0.0991 0.1343
Schistosoma mansoni growth factor receptor-bound protein 0.0085 0.076 0.1029
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0096 0.0991 0.1105
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Trypanosoma brucei protein kinase, putative 0.0099 0.1048 0.6188
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0128 0.1694 0.1888
Echinococcus granulosus raf serine:threonine protein kinase 0.0096 0.0991 0.0991
Schistosoma mansoni suppressor of cytokine signaling 0.0082 0.068 0.0921
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0181 0.2843 0.2843
Echinococcus multilocularis kinase suppressor of Ras 1 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0096 0.0991 1
Brugia malayi Protein kinase domain containing protein 0.0184 0.2908 0.3241
Echinococcus granulosus insulin receptor 0.0096 0.0991 0.0991
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0096 0.0991 0.1343
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Schistosoma mansoni protein kinase 0.0099 0.1048 0.142
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0082 0.068 0.0921
Schistosoma mansoni protein tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis tyrosine protein kinase Srms 0.0178 0.2763 0.3743
Echinococcus granulosus kinase suppressor of Ras 1 0.0096 0.0991 0.0991
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1694 0.2295
Echinococcus granulosus N chimaerin 0.0082 0.068 0.068
Toxoplasma gondii STE kinase 0.0096 0.0991 0.9458
Echinococcus multilocularis activin receptor type 0.0099 0.1048 0.142
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Onchocerca volvulus 0.0178 0.2763 0.308
Onchocerca volvulus 0.0178 0.2763 0.308
Echinococcus multilocularis tyrosine protein kinase csk 0.0096 0.0991 0.1343
Echinococcus granulosus natriuretic peptide receptor 1 0.0096 0.0991 0.0991
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis 0.0082 0.068 0.0921
Brugia malayi Receptor family ligand binding region containing protein 0.0096 0.0991 0.1105
Onchocerca volvulus 0.0082 0.068 0.0758
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0178 0.2763 0.3743
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0096 0.0991 0.1105
Echinococcus granulosus tyrosine protein kinase csk 0.0096 0.0991 0.0991
Onchocerca volvulus 0.0096 0.0991 0.1105
Loa Loa (eye worm) IKK protein kinase 0.0464 0.8972 1
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) serine/threonine protein kinase 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Schistosoma mansoni tyrosine kinase 0.0309 0.561 0.7599
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0178 0.2763 0.3743
Echinococcus granulosus tyrosine protein kinase shark 0.0391 0.7382 0.7382
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0181 0.2843 0.3852
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0195 0.3136 0.3136
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus protein tyrosine kinase 0.0348 0.6466 0.6466
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0082 0.068 0.0921
Toxoplasma gondii protein kinase domain-containing protein 0.0096 0.0991 0.9458
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis SH2 motif 0.0082 0.068 0.0921
Echinococcus granulosus tyrosine protein kinase ABL1 0.0178 0.2763 0.2763
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0082 0.068 0.0758
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Leishmania major hypothetical protein, conserved 0.0096 0.0991 0.5852
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0091 0.0882 0.1194
Echinococcus granulosus activin receptor type 0.0099 0.1048 0.1048
Brugia malayi tRNA modification GTPase TrmE family protein 0.0082 0.068 0.0758
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Onchocerca volvulus 0.0096 0.0991 0.1105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0096 0.0991 0.5852
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0181 0.2843 0.3852
Trypanosoma brucei Flagellum attachment zone protein 20 0.0096 0.0991 0.5852
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0082 0.068 0.0921
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0096 0.0991 0.1343
Echinococcus granulosus tyrosine protein kinase Fyn 0.0181 0.2843 0.2843
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0082 0.068 0.0921
Brugia malayi protein-tyrosine kinase 0.0178 0.2763 0.308
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis c src tyrosine kinase 0.0181 0.2843 0.3852
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis protein kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica tyrosin kinase, putative 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0096 0.0991 0.1105
Trichomonas vaginalis protein tyrosine kinase, putative 0.0096 0.0991 1
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein kinase shark 0.0391 0.7382 1
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0082 0.068 0.0921
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni ephrin receptor 0.0096 0.0991 0.1343
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0195 0.3136 0.4248
Entamoeba histolytica ankyrin repeat protein 0.0096 0.0991 0.3587
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0181 0.2843 0.3852
Brugia malayi Variant SH3 domain containing protein 0.0082 0.068 0.0758
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Echinococcus granulosus signal transduction protein lnk realted 0.0082 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0082 0.068 0.0758
Echinococcus multilocularis kinase protein 0.0091 0.0882 0.1194
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Furin-like cysteine rich region family protein 0.0096 0.0991 0.1105
Echinococcus multilocularis rho associated protein kinase 0.0148 0.2125 0.2878
Leishmania major protein kinase, putative 0.0099 0.1048 0.6188
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Echinococcus multilocularis protein tyrosine kinase 0.0348 0.6466 0.8759
Loa Loa (eye worm) SH2 domain-containing protein 0.0082 0.068 0.0758
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0181 0.2843 0.2843
Echinococcus multilocularis growth factor receptor bound protein 2 0.0085 0.076 0.1029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Plasmodium falciparum protein kinase, putative 0.0096 0.0991 0.9458
Entamoeba histolytica hypothetical protein, conserved 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Echinococcus granulosus tyrosine kinase 0.0096 0.0991 0.0991
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0082 0.068 0.0921
Echinococcus multilocularis raf serine:threonine protein kinase 0.0096 0.0991 0.1343
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0096 0.0991 0.0991
Trichomonas vaginalis protein kinase atn1, putative 0.0096 0.0991 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni nck2/grb4 0.0085 0.076 0.1029
Loa Loa (eye worm) hypothetical protein 0.0085 0.076 0.0847
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0102 0.1121 0.1518
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) SRC-1 0.0181 0.2843 0.3169
Echinococcus granulosus SHC transforming protein 3 0.0082 0.068 0.068
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1694 1
Echinococcus multilocularis tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0178 0.2763 0.2763
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0099 0.1048 0.142
Plasmodium falciparum tyrosine kinase-like protein 0.0096 0.0991 0.9458
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0099 0.1048 0.6188
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0082 0.068 0.0758
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi Variant SH3 domain containing protein 0.0085 0.076 0.0847
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0096 0.0991 0.1343
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Echinococcus multilocularis integrin linked protein kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis tyrosine kinase 0.0178 0.2763 0.3743
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0099 0.1048 0.6188
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0181 0.2843 0.3852
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus granulosus SH2 motif 0.0082 0.068 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0456 0.8796 0.9804
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus epidermal growth factor receptor 0.0096 0.0991 0.0991
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0096 0.0991 0.0991
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0181 0.2843 0.2843
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0082 0.068 0.0921
Schistosoma mansoni growth factor receptor-bound protein 0.0085 0.076 0.1029
Schistosoma mansoni signal transduction protein lnk-related 0.0082 0.068 0.0921
Echinococcus multilocularis heat shock protein 70 0.0096 0.0991 0.1343
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0096 0.0991 0.3587
Echinococcus multilocularis NCK adaptor protein 0.0085 0.076 0.1029
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.068 0.068
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0096 0.0991 0.1343
Echinococcus granulosus tyrosine protein kinase HCK 0.0096 0.0991 0.0991
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0082 0.068 0.068
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis SH2 motif 0.0082 0.068 0.0921
Echinococcus granulosus tyrosine protein kinase Src42A 0.0181 0.2843 0.2843
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0096 0.0991 0.0991
Echinococcus granulosus retinal guanylyl cyclase 2 0.0096 0.0991 0.0991
Brugia malayi hypothetical protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0184 0.2908 0.3241
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0148 0.2125 0.2368
Echinococcus granulosus integrin linked protein kinase 0.0096 0.0991 0.0991
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0096 0.0991 0.1343
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Echinococcus granulosus expressed conserved protein 0.0082 0.068 0.068
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Schistosoma mansoni tyrosine kinase 0.0181 0.2843 0.3852
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0096 0.0991 0.0991
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Entamoeba histolytica ankyrin repeat protein 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/DDR protein kinase 0.0096 0.0991 0.1105
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni vav2 0.0082 0.068 0.0921
Entamoeba histolytica tyrosin kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.068 0.0921
Onchocerca volvulus 0.0173 0.2662 0.2967
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis ephrin type A receptor 4 A 0.0096 0.0991 0.1343
Trypanosoma cruzi protein kinase, putative 0.0096 0.0991 0.5852
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus c src tyrosine kinase 0.0181 0.2843 0.2843
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0181 0.2843 0.3852
Echinococcus granulosus SH2 domain containing adapter protein F 0.0082 0.068 0.068
Brugia malayi Protein kinase domain containing protein 0.0456 0.8796 0.9804
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0991 0.1343
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica SH2 domain containing protein 0.0082 0.068 0.2461
Brugia malayi hypothetical protein 0.0082 0.068 0.0758
Schistosoma mansoni GTPase activating protein 0.0082 0.068 0.0921
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Schistosoma mansoni tyrosine kinase 0.0181 0.2843 0.3852
Echinococcus granulosus protein kinase 0.0096 0.0991 0.0991
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0181 0.2843 0.3852
Brugia malayi cytokine inducible SH2-containing protein 5 0.0082 0.068 0.0758
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Echinococcus multilocularis tyrosine protein kinase Abl 0.0181 0.2843 0.3852
Schistosoma mansoni hypothetical protein 0.0082 0.068 0.0921
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0991 0.1343
Schistosoma mansoni adapter molecule crk 0.0085 0.076 0.1029
Loa Loa (eye worm) hypothetical protein 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Echinococcus multilocularis transfer RNA-Thr 0.0096 0.0991 0.1343
Echinococcus multilocularis SH2 domain containing protein 7 0.0082 0.068 0.0921
Onchocerca volvulus 0.0178 0.2763 0.308
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) hypothetical protein 0.0082 0.068 0.0758
Brugia malayi Protein kinase domain containing protein 0.0351 0.6531 0.7279
Echinococcus multilocularis epidermal growth factor receptor 0.0096 0.0991 0.1343
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Echinococcus granulosus tyrosine protein kinase pr2 0.0096 0.0991 0.0991
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0181 0.2843 0.3852
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0195 0.3136 0.4248
Echinococcus granulosus ephrin type A receptor 4 A 0.0096 0.0991 0.0991
Entamoeba histolytica hypothetical protein 0.0096 0.0991 0.3587
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0085 0.076 0.0847
Trichomonas vaginalis STE family protein kinase 0.0096 0.0991 1
Schistosoma mansoni hypothetical protein 0.0096 0.0991 0.1343
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0096 0.0991 0.1343
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0082 0.068 0.0758
Onchocerca volvulus 0.0082 0.068 0.0758
Echinococcus multilocularis SH2 motif 0.0082 0.068 0.0921
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0096 0.0991 0.1343
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Echinococcus granulosus tyrosine protein kinase csk 0.0096 0.0991 0.0991
Schistosoma mansoni protein kinase 0.0099 0.1048 0.142
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0082 0.068 0.0921
Schistosoma mansoni protein kinase 0.0096 0.0991 0.1343
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Giardia lamblia Kinase, NEK 0.0096 0.0991 1
Schistosoma mansoni tyrosine kinase 0.0195 0.3136 0.4248
Brugia malayi RhoGAP domain containing protein 0.0082 0.068 0.0758
Brugia malayi SH2 domain containing protein 0.0082 0.068 0.0758
Echinococcus multilocularis kinase protein 0.0091 0.0882 0.1194
Echinococcus multilocularis tyrosine protein kinase pr2 0.0096 0.0991 0.1343
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Brugia malayi Immunoglobulin I-set domain containing protein 0.0201 0.3265 0.3639
Brugia malayi Variant SH3 domain containing protein 0.0082 0.068 0.0758
Brugia malayi Tensin 0.0082 0.068 0.0758
Onchocerca volvulus 0.0146 0.2068 0.2305
Plasmodium falciparum protein kinase, putative 0.0099 0.1048 1
Brugia malayi hypothetical protein 0.0096 0.0991 0.1105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0991 0.3587
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Loa Loa (eye worm) TK/ABL protein kinase 0.0178 0.2763 0.308
Echinococcus multilocularis tyrosine protein kinase csk 0.0096 0.0991 0.1343
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0082 0.068 0.0921
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0096 0.0991 0.9458
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0991 0.1105
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0096 0.0991 0.9458
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0991 1
Trichomonas vaginalis TK family protein kinase 0.0096 0.0991 1
Entamoeba histolytica protein kinase, putative 0.0096 0.0991 0.3587
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0184 0.29 0.29
Echinococcus multilocularis tyrosine protein kinase HCK 0.0096 0.0991 0.1343
Schistosoma mansoni hypothetical protein 0.0082 0.068 0.0921
Echinococcus granulosus NCK adaptor protein 0.0085 0.076 0.076
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0102 0.1121 0.1121
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0099 0.1048 0.6188
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0099 0.1048 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0181 0.2843 0.2843
Brugia malayi Tyrosine-protein kinase abl-1 0.0181 0.2843 0.3169
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus mitogen activated protein kinase 11 0.0128 0.1694 0.1694
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0096 0.0991 0.1343
Loa Loa (eye worm) TK/FER protein kinase 0.0178 0.2763 0.308
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Echinococcus multilocularis protein kinase 0.0096 0.0991 0.1343
Brugia malayi integrin-linked kinase 0.0096 0.0991 0.1105
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Onchocerca volvulus 0.0178 0.2763 0.308
Schistosoma mansoni protein kinase 0.0099 0.1048 0.142
Entamoeba histolytica serine/threonine kinase, putative 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni shc transforming protein 0.0082 0.068 0.0921
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni tyrosine kinase 0.0096 0.0991 0.1343
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Entamoeba histolytica tyrosine kinase, putative 0.0096 0.0991 0.3587
Plasmodium falciparum tyrosine kinase-like protein 0.0096 0.0991 0.9458
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0096 0.0991 0.1343
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0096 0.0991 0.3587
Onchocerca volvulus 0.0082 0.068 0.0758
Echinococcus multilocularis tensin 0.0082 0.068 0.0921
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0184 0.2908 0.3939
Loa Loa (eye worm) TK protein kinase 0.0096 0.0991 0.1105
Trichomonas vaginalis TKL family protein kinase 0.0096 0.0991 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0178 0.2763 0.2763
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1694 1
Onchocerca volvulus 0.0096 0.0991 0.1105
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Echinococcus granulosus SH2 motif 0.0082 0.068 0.068
Brugia malayi Protein kinase domain containing protein 0.0096 0.0991 0.1105
Loa Loa (eye worm) TK/FER protein kinase 0.0096 0.0991 0.1105

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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