Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0425 | 0.0254 | 0.0254 |
Toxoplasma gondii | AGC kinase | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0379 | 0.0038 | 0.0038 |
Brugia malayi | Protein kinase domain containing protein | 0.0382 | 0.0055 | 0.0067 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0808 | 0.203 | 0.2094 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0379 | 0.0038 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.0254 | 0.0262 |
Entamoeba histolytica | protein kinase, putative | 0.0382 | 0.0055 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0382 | 0.0055 | 0.0055 |
Schistosoma mansoni | serine/threonine kinase | 0.0382 | 0.0055 | 0.0055 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0382 | 0.0055 | 0.0057 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0808 | 0.203 | 0.203 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0382 | 0.0055 | 0.0055 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0425 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0516 | 0.0674 | 0.0696 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0382 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0382 | 0.0055 | 0.0057 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.1716 | 0.625 | 0.625 |
Schistosoma mansoni | unc-13 (munc13) | 0.0425 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0382 | 0.0055 | 0.0057 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0382 | 0.0055 | 0.0057 |
Entamoeba histolytica | protein kinase, putative | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0382 | 0.0055 | 0.0055 |
Brugia malayi | Protein kinase domain containing protein | 0.0382 | 0.0055 | 0.0067 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0382 | 0.0055 | 0.0055 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2524 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0382 | 0.0055 | 0.0055 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0382 | 0.0055 | 0.0055 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0379 | 0.0038 | 0.0038 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0382 | 0.0055 | 0.0055 |
Echinococcus granulosus | protein kinase C gamma type | 0.2153 | 0.8279 | 0.8279 |
Schistosoma mansoni | unc-13 (munc13) | 0.0425 | 0.0254 | 0.0254 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0382 | 0.0055 | 0.5 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0382 | 0.0055 | 0.0057 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0382 | 0.0055 | 0.0057 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0379 | 0.0038 | 0.0038 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.2524 | 1 | 1 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0379 | 0.0038 | 0.0046 |
Onchocerca volvulus | 0.0425 | 0.0254 | 1 | |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.1779 | 0.6542 | 0.6749 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.1716 | 0.625 | 0.625 |
Echinococcus granulosus | unc 13 munc13 | 0.0425 | 0.0254 | 0.0254 |
Echinococcus granulosus | NDR protein kinase | 0.0382 | 0.0055 | 0.0055 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.1716 | 0.625 | 0.625 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0808 | 0.203 | 0.203 |
Brugia malayi | C1-like domain containing protein | 0.0379 | 0.0038 | 0.0046 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0382 | 0.0055 | 0.0055 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0382 | 0.0055 | 0.0055 |
Echinococcus granulosus | protein kinase c iota type | 0.0753 | 0.1776 | 0.1776 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0382 | 0.0055 | 0.0055 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2524 | 1 | 1 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0379 | 0.0038 | 0.004 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0382 | 0.0055 | 0.0067 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0808 | 0.203 | 0.203 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0753 | 0.1776 | 0.1776 |
Brugia malayi | protein kinase C II. | 0.0808 | 0.203 | 0.2457 |
Brugia malayi | Protein kinase domain containing protein | 0.0382 | 0.0055 | 0.0067 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0379 | 0.0038 | 0.0038 |
Brugia malayi | protein kinase C3,putative | 0.0379 | 0.0038 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0504 | 0.0619 | 0.0639 |
Schistosoma mansoni | protein kinase C | 0.0425 | 0.0254 | 0.0254 |
Entamoeba histolytica | protein kinase, putative | 0.0382 | 0.0055 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0382 | 0.0055 | 0.0055 |
Brugia malayi | RasGEF domain containing protein | 0.2085 | 0.7962 | 0.9636 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.2458 | 0.9693 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2087 | 0.797 | 0.8223 |
Echinococcus multilocularis | serine threonine protein kinase | 0.2153 | 0.8279 | 0.8279 |
Brugia malayi | Protein kinase c protein 2 | 0.215 | 0.8262 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0753 | 0.1776 | 0.1776 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0382 | 0.0055 | 0.0067 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0382 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0382 | 0.0055 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.1716 | 0.625 | 0.6447 |
Schistosoma mansoni | protein kinase C mu | 0.0379 | 0.0038 | 0.0038 |
Trichomonas vaginalis | AGC family protein kinase | 0.0382 | 0.0055 | 1 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0382 | 0.0055 | 0.0055 |
Brugia malayi | Protein kinase domain containing protein | 0.0379 | 0.0038 | 0.0046 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0425 | 0.0254 | 0.0254 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.