TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 444.593 | Formula: C22H32N6O2S
H donors: 1 H acceptors: 2 LogP: 2.4 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CCCN1CCN(CC1)CCCNC(=O)Cn1nc(CC)n2c(c1=O)cc1c2ccs1
InChi: 1S/C22H32N6O2S/c1-3-8-25-10-12-26(13-11-25)9-5-7-23-21(29)16-27-22(30)18-15-19-17(6-14-31-19)28(18)20(4-2)24-27/h6,14-15H,3-5,7-13,16H2,1-2H3,(H,23,29)
InChiKey: XZUWYWPGXHZLNG-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	neuropeptide Y receptor	0.009	0.0213	0.0213
Schistosoma mansoni	hypothetical protein	0.0101	0.0243	0.0239
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0062	0.0139	0.0752
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0026	0.0045	0.0223
Brugia malayi	Cation transporter family protein	0.0178	0.0442	0.0442
Schistosoma mansoni	neuropeptide receptor	0.009	0.0213	0.021
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	1
Schistosoma mansoni	hypothetical protein	0.0011	0.0007	0.0003
Brugia malayi	hypothetical protein	0.0014	0.0015	0.0015
Plasmodium vivax	aspartyl protease, putative	0.0017	0.0022	0.005
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Echinococcus granulosus	solute carrier family 22	0.0014	0.0015	0.0014
Plasmodium falciparum	plasmepsin X	0.0017	0.0022	0.0061
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	biogenic amine receptor	0.009	0.0213	0.021
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.009	0.0213	0.0213
Onchocerca volvulus		0.0091	0.0216	0.1273
Plasmodium falciparum	protein kinase 6	0.043	0.1102	1
Onchocerca volvulus		0.0014	0.0015	0.0067
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.001	0.0004	0.0003
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0035	0.007	1
Onchocerca volvulus		0.0014	0.0015	0.0067
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.009	0.0213	0.0213
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.006	0.851
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Plasmodium falciparum	importin beta, putative	0.0035	0.0069	0.0495
Loa Loa (eye worm)	ACC-1 protein	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0772	0.1996	0.1996
Brugia malayi	Dopamine receptor	0.009	0.0213	0.0213
Onchocerca volvulus		0.0178	0.0442	0.2627
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.003	0.0057	0.0057
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0028	0.0052	0.0221
Brugia malayi	Carboxylesterase family protein	0.0648	0.1671	0.1671
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.003	0.0057	0.0255
Onchocerca volvulus		0.009	0.0213	0.1257
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.001	0.0004	0.0003
Onchocerca volvulus		0.0017	0.0022	0.0107
Toxoplasma gondii	hypothetical protein	0.0033	0.0063	0.0672
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.009	0.0213	0.1257
Loa Loa (eye worm)	G-protein coupled receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0648	0.1671	0.1668
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Echinococcus multilocularis	sex peptide receptor	0.009	0.0213	0.0213
Echinococcus granulosus	sex peptide receptor	0.009	0.0213	0.0213
Onchocerca volvulus	Putative nachr subunit	0.0178	0.0442	0.2627
Onchocerca volvulus		0.009	0.0213	0.1257
Echinococcus multilocularis	transient receptor potential ion channel A	0.0093	0.022	0.0219
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Echinococcus granulosus	solute carrier family 22	0.0014	0.0015	0.0014
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Brugia malayi	Carboxylesterase family protein	0.3835	1	1
Schistosoma mansoni	hypothetical protein	0.0086	0.0203	0.0199
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0178	0.0442	0.0442
Echinococcus multilocularis	nAChR subunit	0.0178	0.0442	0.0441
Echinococcus granulosus	orexin receptor type 2	0.009	0.0213	0.0213
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0086	0.0204	0.0203
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	g protein coupled receptor	0.009	0.0213	0.0213
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.009	0.0213	0.0213
Plasmodium vivax	aspartyl proteinase, putative	0.0017	0.0022	0.005
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0014	0.0015	0.0055
Onchocerca volvulus		0.0178	0.0442	0.2627
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0178	0.0442	0.0441
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Loa Loa (eye worm)	carboxylesterase	0.0648	0.1671	0.1671
Echinococcus multilocularis	nAChR subunit	0.0091	0.0216	0.0215
Onchocerca volvulus		0.0014	0.0015	0.0067
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.009	0.0213	0.0213
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Echinococcus multilocularis	FTZ F1 alpha	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.001	0.0004	0.0003
Echinococcus granulosus	g protein coupled receptor	0.009	0.0213	0.0213
Echinococcus granulosus	neuropeptides capa receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Schistosoma mansoni	cpg binding protein	0.003	0.0056	0.0052
Echinococcus multilocularis	para nitrobenzyl esterase	0.0648	0.1671	0.1671
Onchocerca volvulus		0.0014	0.0015	0.0067
Brugia malayi	Tachykinin-like peptides receptor 99D	0.009	0.0213	0.0213
Brugia malayi	nuclear receptor NHR-88	0.001	0.0004	0.0003
Brugia malayi	Steroid receptor seven-up type 2	0.001	0.0004	0.0003
Leishmania major	importin beta-1 subunit, putative	0.0028	0.0052	0.6599
Schistosoma mansoni	neurotransmitter gated ion channel	0.0086	0.0204	0.02
Onchocerca volvulus		0.0014	0.0015	0.0067
Loa Loa (eye worm)	neuronal acetylcholine receptor protein	0.0086	0.0204	0.0203
Schistosoma mansoni	neuropeptide f receptor 76f	0.009	0.0213	0.021
Plasmodium vivax	tryptophan-rich antigen (Pv-fam-a)	0.0524	0.1348	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.009	0.0213	0.0213
Plasmodium falciparum	proline--tRNA ligase	0.0035	0.007	0.051
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	0.0017	0.0022	0.0094
Echinococcus multilocularis	glycine receptor subunit beta	0.0178	0.0442	0.0441
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0015	0.0014
Onchocerca volvulus		0.009	0.0213	0.1257
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Schistosoma mansoni	amine GPCR	0.009	0.0213	0.021
Loa Loa (eye worm)	TYRA-2 protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	melatonin receptor type 1A	0.009	0.0213	0.0213
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0031	0.0059	0.0329
Onchocerca volvulus		0.009	0.0213	0.1257
Schistosoma mansoni	hypothetical protein	0.009	0.0213	0.021
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0164	0.0406	0.2932
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.006	0.0271
Echinococcus multilocularis	transient receptor potential gamma protein	0.0096	0.0228	0.0228
Brugia malayi	Pepsin A precursor	0.0017	0.0022	0.0021
Brugia malayi	major facilitator superfamily protein	0.0014	0.0015	0.0015
Schistosoma mansoni	transient receptor potential channel 4	0.0096	0.0228	0.0225
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.006	0.851
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0015	0.0015
Echinococcus granulosus	neuroligin	0.0648	0.1671	0.1671
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0011	0.0007	0.0006
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0094	0.0225	0.0224
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0178	0.0442	0.0438
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.009	0.0213	0.0213
Echinococcus multilocularis	short transient receptor potential channel 6	0.0063	0.0143	0.0143
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0178	0.0442	0.0441
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Brugia malayi	neuropeptide F receptor	0.009	0.0213	0.0213
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0091	0.0216	0.0212
Loa Loa (eye worm)	hypothetical protein	0.006	0.0135	0.0134
Schistosoma mansoni	neurotransmitter gated ion channel	0.0086	0.0204	0.02
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.001	0.0004	0.0003
Onchocerca volvulus		0.0028	0.0052	0.0288
Onchocerca volvulus		0.0648	0.1671	1
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0035	0.007	0.0779
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0026	0.0045	0.0044
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.007	1
Brugia malayi	hypothetical protein	0.0086	0.0204	0.0203
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0062	0.0139	0.0752
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0031	0.0059	0.8362
Echinococcus granulosus	alpha 1A adrenergic receptor	0.009	0.0213	0.0213
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0026	0.0045	0.0044
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0037	0.0033
Echinococcus multilocularis	fmrfamide receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0564	0.145	0.145
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0059	0.0058
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0022	0.0021
Echinococcus granulosus	acetylcholinesterase	0.3835	1	1
Loa Loa (eye worm)	carboxylesterase	0.0648	0.1671	0.1671
Brugia malayi	Probable ClpP-like protease	0.0094	0.0225	0.0224
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Brugia malayi	Cation transporter family protein	0.0178	0.0442	0.0442
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0062	0.0139	0.0139
Brugia malayi	Serotonin receptor	0.009	0.0213	0.0213
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0014	0.0015	0.0011
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0091	0.0216	0.0216
Plasmodium vivax	CDK-related protein kinase 6, putative	0.043	0.1102	0.8155
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0043	0.0042
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.001	0.0004	0.0003
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.009	0.0213	0.021
Schistosoma mansoni	protein kinase	0.0031	0.0059	0.0055
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.001	0.0004	0.0003
Echinococcus granulosus	synaptic vesicle 2 protein	0.0014	0.0015	0.0014
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Onchocerca volvulus		0.0014	0.0015	0.0067
Echinococcus granulosus	tm gpcr rhodopsin	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0069	0.0068
Schistosoma mansoni	cathepsin D (A01 family)	0.0017	0.0022	0.0018
Brugia malayi	putative neuropeptide receptor	0.009	0.0213	0.0213
Schistosoma mansoni	amine GPCR	0.009	0.0213	0.021
Echinococcus granulosus	nAChR subunit	0.0091	0.0216	0.0215
Schistosoma mansoni	cpg binding protein	0.003	0.0056	0.0052
Brugia malayi	steroid hormone receptor	0.001	0.0004	0.0003
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Schistosoma mansoni	biogenic amine receptor	0.009	0.0213	0.021
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.006	0.8107
Echinococcus granulosus	neuropeptides capa receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Brugia malayi	Sugar transporter family protein	0.0014	0.0015	0.0015
Onchocerca volvulus		0.009	0.0213	0.1257
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.009	0.0213	0.0213
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0043	0.5028
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.006	0.0271
Echinococcus granulosus	allatostatin A receptor	0.009	0.0213	0.0213
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.001	0.0004	0.0003
Brugia malayi	major facilitator superfamily protein	0.0014	0.0015	0.0015
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0648	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0031	0.006	0.8107
Brugia malayi	G protein-coupled receptor	0.009	0.0213	0.0213
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.001	0.0004	0.0003
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0178	0.0442	0.0441
Onchocerca volvulus		0.0014	0.0015	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Loa Loa (eye worm)	aspartyl protease 6	0.0017	0.0022	0.0021
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Onchocerca volvulus		0.009	0.0213	0.1257
Leishmania major	protein kinase, putative	0.0031	0.0059	0.7919
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0042	0.0042
Echinococcus granulosus	lysyl tRNA synthetase	0.0023	0.0037	0.0036
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0033	0.0063	0.0359
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.0019	0.0028	0.0078
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0033	0.0063	0.044
Schistosoma mansoni	serine-rich repeat protein	0.0086	0.0203	0.0199
Onchocerca volvulus		0.0014	0.0015	0.0067
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.009	0.0213	0.021
Echinococcus multilocularis	ecdysone induced protein 78C	0.001	0.0004	0.0003
Loa Loa (eye worm)	steroid hormone receptor	0.001	0.0004	0.0003
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0178	0.0442	0.0441
Schistosoma mansoni	hypothetical protein	0.009	0.0213	0.021
Schistosoma mansoni	opsin-like receptor	0.009	0.0213	0.021
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Brugia malayi	aspartic protease BmAsp-1, identical	0.0017	0.0022	0.0021
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Schistosoma mansoni	cpg binding protein	0.0028	0.0052	0.0048
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.003	0.0057	0.0053
Echinococcus granulosus	solute carrier family 22	0.0014	0.0015	0.0014
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0031	0.0059	0.0617
Plasmodium vivax	proline--tRNA ligase, putative	0.0035	0.007	0.0416
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.001	0.0004	0.0003
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0164	0.0406	0.5495
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0054	0.0118	0.1452
Onchocerca volvulus		0.0648	0.1671	1
Brugia malayi	G-protein coupled receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Brugia malayi	putative neuropeptide receptor NPR1	0.009	0.0213	0.0213
Schistosoma mansoni	acetylcholine receptor-related	0.0086	0.0204	0.02
Echinococcus granulosus	neuropeptide FF receptor 2	0.009	0.0213	0.0213
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.0043	0.0392
Loa Loa (eye worm)	aspartic protease BmAsp-1	0.0017	0.0022	0.0021
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.009	0.0213	0.021
Schistosoma mansoni	memapsin-2 (A01 family)	0.0418	0.1071	0.1067
Brugia malayi	GnHR receptor homolog	0.009	0.0213	0.0213
Schistosoma mansoni	ran	0.0026	0.0045	0.0041
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0004	0.0003
Echinococcus multilocularis	carboxylesterase 5A	0.3835	1	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0086	0.0204	0.0203
Brugia malayi	hypothetical protein	0.0086	0.0204	0.0203
Echinococcus multilocularis	voltage dependent calcium channel subunit	0.0167	0.0413	0.0412
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.009	0.0213	0.0213
Echinococcus multilocularis	G protein coupled receptor 139	0.009	0.0213	0.0213
Trichomonas vaginalis	importin beta-1, putative	0.0028	0.0052	0.0221
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0648	0.1671	0.1671
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.0037	0.0033
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0031	0.0059	0.0058
Loa Loa (eye worm)	neuropeptide F receptor	0.009	0.0213	0.0213
Echinococcus granulosus	biogenic amine 5HT receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	importin subunit beta 1	0.0035	0.0069	0.0068
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.001	0.0004	0.0003
Echinococcus granulosus	ecdysone induced protein 78C	0.001	0.0004	0.0003
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0043	0.0256
Echinococcus multilocularis	neuropeptides capa receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.0017	0.0022	0.0021
Trichomonas vaginalis	spcc417.12 protein, putative	0.0648	0.1671	1
Echinococcus granulosus	neuropeptide receptor A26	0.009	0.0213	0.0213
Plasmodium falciparum	lysine--tRNA ligase	0.0023	0.0037	0.0201
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0026	0.0045	0.5369
Echinococcus multilocularis	allatostatin A receptor	0.009	0.0213	0.0213
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0648	0.1671	1
Echinococcus multilocularis	cpg binding protein	0.003	0.0056	0.0055
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.006	0.0271
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Brugia malayi	hypothetical protein	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0031	0.006	0.851
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Brugia malayi	hypothetical protein	0.0025	0.0043	0.0042
Echinococcus multilocularis	acetylcholinesterase	0.3835	1	1
Schistosoma mansoni	nAChR subunit	0.0086	0.0204	0.02
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0178	0.0442	0.0441
Brugia malayi	Carboxylesterase family protein	0.0648	0.1671	0.1671
Echinococcus multilocularis	neuropeptide s receptor	0.009	0.0213	0.0213
Onchocerca volvulus		0.0648	0.1671	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.009	0.0213	0.0213
Onchocerca volvulus		0.009	0.0213	0.1257
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.003	0.0057	0.0057
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0178	0.0442	0.0441
Schistosoma mansoni	amine GPCR	0.009	0.0213	0.021
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0014	0.0015	0.0055
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Plasmodium vivax	aspartyl protease, putative	0.0017	0.0022	0.005
Brugia malayi	ORL1-like opioid receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0178	0.0442	0.0442
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Brugia malayi	ecdysteroid receptor	0.001	0.0004	0.0003
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Leishmania major	lysyl-tRNA synthetase, putative	0.0023	0.0037	0.395
Echinococcus granulosus	cpg binding protein	0.003	0.0056	0.0055
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.009	0.0213	0.0213
Schistosoma mansoni	myosin xvIII	0.009	0.0213	0.021
Echinococcus multilocularis	glycine receptor subunit beta	0.0178	0.0442	0.0441
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.003	0.0057	0.0057
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0015	0.0015
Echinococcus multilocularis	g-protein coupled receptor	0.009	0.0213	0.0213
Schistosoma mansoni	biogenic amine receptor	0.009	0.0213	0.021
Echinococcus multilocularis	lysyl tRNA synthetase	0.0023	0.0037	0.0036
Loa Loa (eye worm)	sugar transporter	0.0101	0.0243	0.0242
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Plasmodium falciparum	plasmepsin VII	0.0017	0.0022	0.0061
Echinococcus granulosus	tachykinin peptides receptor 99D	0.009	0.0213	0.0213
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0031	0.0059	0.0404
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.009	0.0213	0.021
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.009	0.0213	0.0213
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Echinococcus multilocularis	neuropeptide Y receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.0017	0.0022	0.0021
Brugia malayi	hypothetical protein	0.0016	0.002	0.0019
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.001	0.0004	0.0003
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0004	0.0003
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.001	0.0004	0.0003
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0091	0.0216	0.0216
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.009	0.0213	0.0213
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.0017	0.0022	0.0021
Plasmodium vivax	lysine--tRNA ligase, putative	0.0023	0.0037	0.0164
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.009	0.0213	0.0213
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0094	0.0225	0.2947
Schistosoma mansoni	BC026374 protein (S09 family)	0.0648	0.1671	0.1668
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0031	0.0059	0.0058
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0031	0.0059	0.0329
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0031	0.0059	0.0329
Brugia malayi	Nuclear hormone receptor-like 1	0.001	0.0004	0.0003
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.009	0.0213	0.0213
Onchocerca volvulus		0.009	0.0213	0.1257
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Onchocerca volvulus		0.0091	0.0216	0.1273
Brugia malayi	excitatory GABA receptor EXP-1A	0.0178	0.0442	0.0442
Plasmodium falciparum	plasmepsin II	0.0017	0.0022	0.0061
Schistosoma mansoni	peptidase Clp (S14 family)	0.0094	0.0225	0.0221
Plasmodium falciparum	hexose transporter	0.0101	0.0243	0.2094
Brugia malayi	photoreceptor-specific nuclear receptor	0.001	0.0004	0.0003
Echinococcus granulosus	voltage dependent calcium channel subunit	0.0167	0.0413	0.0412
Schistosoma mansoni	glucose transport protein	0.0101	0.0243	0.0239
Loa Loa (eye worm)	neuropeptide F receptor	0.009	0.0213	0.0213
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0026	0.0045	0.0044
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.009	0.0213	0.021
Echinococcus multilocularis	voltage dependent calcium channel subunit	0.0366	0.0935	0.0934
Trichomonas vaginalis	conserved hypothetical protein	0.0101	0.0243	0.1374
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0037	0.0036
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Onchocerca volvulus		0.0648	0.1671	1
Echinococcus granulosus	para nitrobenzyl esterase	0.0648	0.1671	0.1671
Echinococcus granulosus	glycine receptor subunit beta	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Echinococcus granulosus	neuropeptide s receptor	0.009	0.0213	0.0213
Echinococcus granulosus	somatostatin receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Onchocerca volvulus		0.009	0.0213	0.1257
Onchocerca volvulus		0.009	0.0213	0.1257
Echinococcus granulosus	G protein coupled receptor 139	0.009	0.0213	0.0213
Echinococcus granulosus	dro:myosuppressin receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Trypanosoma brucei	importin beta-1 subunit, putative	0.0035	0.0069	0.9769
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Giardia lamblia	Prolyl-tRNA synthetase	0.003	0.0057	1
Trypanosoma cruzi	hexose transporter, putative	0.0017	0.0023	0.1383
Echinococcus granulosus	7tm_1 domain containing protein	0.009	0.0213	0.0213
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.009	0.0213	0.0213
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0015	0.0014
Echinococcus multilocularis	neuropeptides capa receptor	0.009	0.0213	0.0213
Mycobacterium ulcerans	sugar transporter	0.0014	0.0015	0.0055
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Onchocerca volvulus		0.009	0.0213	0.1257
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Onchocerca volvulus		0.0014	0.0015	0.0067
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0086	0.0204	0.02
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0026	0.0045	0.7043
Onchocerca volvulus	Neuropeptide F receptor homolog	0.009	0.0213	0.1257
Echinococcus granulosus	snurportin 1	0.0372	0.0949	0.0948
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0022	0.0021
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0052	0.0052
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.009	0.0213	0.0213
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Plasmodium vivax	aspartyl proteinase, putative	0.0017	0.0022	0.005
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0178	0.0442	0.0438
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.009	0.0213	0.021
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0178	0.0442	0.0441
Onchocerca volvulus	Putative transporter	0.0014	0.0015	0.0067
Schistosoma mansoni	alpha-1 adrenergic receptor	0.009	0.0213	0.021
Schistosoma mansoni	amine GPCR	0.009	0.0213	0.021
Onchocerca volvulus		0.0014	0.0015	0.0067
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.009	0.0213	0.0213
Toxoplasma gondii	aspartyl protease ASP1	0.0017	0.0022	0.0094
Toxoplasma gondii	eukaryotic aspartyl protease superfamily protein	0.0017	0.0022	0.0094
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.0036	0.0071	0.007
Schistosoma mansoni	growth hormone secretagogue receptor	0.009	0.0213	0.021
Trichomonas vaginalis	ran, putative	0.0026	0.0045	0.018
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0648	0.1671	0.1668
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Schistosoma mansoni	dihydropyridine-sensitive l-type calcium channel	0.0081	0.0188	0.0184
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0019	0.0028	0.0078
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0043	0.0256
Echinococcus multilocularis	General substrate transporter	0.0087	0.0205	0.0205
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Echinococcus granulosus	TRP transient receptor potential channel	0.0036	0.0071	0.007
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.009	0.0213	0.021
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Schistosoma mansoni	adenoreceptor	0.009	0.0213	0.021
Brugia malayi	AKH receptor	0.009	0.0213	0.0213
Schistosoma mansoni	serine/threonine protein kinase	0.0031	0.0059	0.0055
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0031	0.0059	0.0329
Echinococcus granulosus	calcium dependent protein kinase	0.0029	0.0054	0.0053
Echinococcus granulosus	transient receptor potential gamma protein	0.0096	0.0228	0.0228
Brugia malayi	hypothetical protein	0.0648	0.1671	0.1671
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.002	0.003	0.0088
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Mycobacterium ulcerans	carboxylesterase, LipT	0.0648	0.1671	1
Schistosoma mansoni	hypothetical protein	0.0372	0.0949	0.0946
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Mycobacterium ulcerans	integral membrane transport protein	0.0014	0.0015	0.0055
Onchocerca volvulus		0.0014	0.0015	0.0067
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0035	0.007	1
Trichomonas vaginalis	CAMK family protein kinase	0.0031	0.0059	0.0265
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Schistosoma mansoni	gliotactin	0.0648	0.1671	0.1668
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.006	0.0271
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0178	0.0442	0.0441
Brugia malayi	Serotonin receptor	0.009	0.0213	0.0213
Schistosoma mansoni	opsin-like receptor	0.009	0.0213	0.021
Brugia malayi	Acetylcholine receptor protein, alpha-like chain 1 precursor	0.0086	0.0204	0.0203
Onchocerca volvulus		0.0086	0.0204	0.1198
Brugia malayi	neuropeptide F receptor	0.009	0.0213	0.0213
Leishmania major	glucose transporter, lmgt3	0.0031	0.006	0.8107
Echinococcus multilocularis	somatostatin receptor	0.009	0.0213	0.0213
Brugia malayi	lysyl-tRNA synthetase	0.0023	0.0037	0.0036
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Echinococcus granulosus	carboxylesterase 5A	0.3835	1	1
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0178	0.0442	0.0441
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0094	0.0225	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.009	0.0213	0.021
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.001	0.0004	0.0003
Mycobacterium tuberculosis	Carboxylesterase LipT	0.0648	0.1671	1
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0052	0.0051
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0026	0.0045	0.6354
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0086	0.0204	0.0203
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0094	0.0225	0.2947
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0015	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Toxoplasma gondii	protein kinase, putative	0.0286	0.0726	1
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Echinococcus granulosus	short transient receptor potential channel 6	0.0063	0.0143	0.0143
Plasmodium vivax	plasmepsin V, putative	0.0017	0.0022	0.005
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0037	0.0186
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0014	0.0015	0.0014
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Echinococcus granulosus	FTZ F1 alpha	0.001	0.0004	0.0003
Echinococcus multilocularis	g protein coupled receptor	0.009	0.0213	0.0213
Brugia malayi	Transient-receptor-potential like protein	0.0036	0.0071	0.0071
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	0.0017	0.0022	0.004
Brugia malayi	hypothetical protein	0.0086	0.0204	0.0203
Brugia malayi	G protein-coupled receptor F59B2.13	0.009	0.0213	0.0213
Onchocerca volvulus		0.0014	0.0015	0.0067
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0015	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Brugia malayi	Neuronal acetylcholine receptor protein, alpha-2 chain precursor	0.0086	0.0204	0.0203
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0043	0.5028
Echinococcus multilocularis	calcium dependent protein kinase	0.0029	0.0054	0.0053
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	protein kinase	0.0031	0.0059	0.0055
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0014	0.0015	0.0014
Trypanosoma brucei	glucose transporter 2A	0.0031	0.006	0.851
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	0.1928
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.009	0.0213	0.021
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0023	0.0037	0.0453
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.003	0.0057	0.0057
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus granulosus	tm gpcr rhodopsin	0.009	0.0213	0.0213
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0023	0.0037	0.395
Echinococcus granulosus	neuropeptide Y receptor	0.009	0.0213	0.0213
Schistosoma mansoni	transient receptor potential channel	0.0096	0.0228	0.0225
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.007	1
Brugia malayi	Sugar transporter family protein	0.0014	0.0015	0.0015
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0372	0.0949	0.0948
Echinococcus multilocularis	serotonin receptor	0.009	0.0213	0.0213
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus		0.0014	0.0015	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0022	0.0021
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus		0.0017	0.0022	0.0107
Loa Loa (eye worm)	hypothetical protein	0.3835	1	1
Echinococcus granulosus	short transient receptor potential channel 6	0.0063	0.0143	0.0143
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Echinococcus granulosus	nAChR subunit	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Schistosoma mansoni	neuropeptide receptor	0.009	0.0213	0.021
Toxoplasma gondii	aspartyl protease	0.0017	0.0022	0.0094
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Brugia malayi	Carboxylesterase family protein	0.0648	0.1671	0.1671
Toxoplasma gondii	facilitative glucose transporter GT1	0.0101	0.0243	0.3201
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0178	0.0442	0.0438
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.006	0.8107
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0091	0.0216	0.0212
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0178	0.0442	0.0441
Toxoplasma gondii	HEAT repeat-containing protein	0.0035	0.0069	0.0756
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0033	0.0063	0.2604
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0091	0.0216	0.0216
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.001	0.0004	0.0003
Leishmania major	GTP-binding protein, putative	0.0026	0.0045	0.5369
Echinococcus multilocularis	thyroid hormone receptor alpha	0.001	0.0004	0.0003
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Entamoeba histolytica	hypothetical protein	0.0028	0.0052	0.0819
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus		0.009	0.0213	0.1257
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0178	0.0442	0.0441
Brugia malayi	aspartic protease BmAsp-2, identical	0.0017	0.0022	0.0021
Echinococcus multilocularis	neuropeptide receptor A26	0.009	0.0213	0.0213
Leishmania major	hypothetical protein, conserved	0.0025	0.0043	0.5028
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.001	0.0004	0.0003
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.009	0.0213	0.0213
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.0062	0.0139	0.5675
Trypanosoma brucei	importin beta-1 subunit, putative	0.0035	0.0069	0.9769
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0086	0.0204	0.0203
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0011	0.0007	0.0006
Schistosoma mansoni	opsin-like receptor	0.009	0.0213	0.021
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus granulosus	solute carrier family 22	0.0014	0.0015	0.0014
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0028	0.0052	0.6599
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0026	0.0045	0.5369
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Plasmodium falciparum	plasmepsin I	0.0017	0.0022	0.0061
Onchocerca volvulus		0.009	0.0213	0.1257
Plasmodium falciparum	plasmepsin IV	0.0017	0.0022	0.0061
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Schistosoma mansoni	sugar transporter	0.0014	0.0015	0.0011
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0031	0.0059	0.0404
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0004	0.0003
Plasmodium vivax	importin-beta 2, putative	0.0035	0.0069	0.0403
Brugia malayi	sulfakinin receptor protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.006	0.0271
Echinococcus multilocularis	neuroligin	0.0648	0.1671	0.1671
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0164	0.0406	0.3595
Giardia lamblia	Lysyl-tRNA synthetase	0.0023	0.0037	0.5182
Onchocerca volvulus		0.0086	0.0204	0.1198
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0014	0.0015	0.0014
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.003	0.0057	0.1135
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0178	0.0442	0.0438
Brugia malayi	follicle stimulating hormone receptor	0.009	0.0213	0.0213
Leishmania major	glucose transporter, lmgt2	0.0031	0.006	0.8107
Brugia malayi	Cation transporter family protein	0.0178	0.0442	0.0442
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0031	0.0059	0.0617
Echinococcus multilocularis	neuropeptide receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0004	0.0003
Echinococcus granulosus	voltage dependent calcium channel subunit	0.0366	0.0935	0.0934
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0648	0.1671	0.1668
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0086	0.0204	0.0203
Loa Loa (eye worm)	acetylcholinesterase 1	0.3835	1	1
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0094	0.0225	0.0224
Echinococcus granulosus	g protein coupled receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0012	0.001	0.001
Toxoplasma gondii	lysine-tRNA ligase	0.0023	0.0037	0.0308
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.009	0.0213	0.021
Entamoeba histolytica	protein kinase, putative	0.0031	0.0059	0.1227
Onchocerca volvulus		0.0178	0.0442	0.2627
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0094	0.0225	0.1572
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Onchocerca volvulus		0.0178	0.0442	0.2627
Plasmodium falciparum	plasmepsin VIII, putative	0.0017	0.0022	0.0061
Loa Loa (eye worm)	G-protein coupled receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Schistosoma mansoni	neuropeptide receptor	0.009	0.0213	0.021
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.001	0.0004	0.0003
Echinococcus granulosus	importin subunit beta 1	0.0035	0.0069	0.0068
Loa Loa (eye worm)	hypothetical protein	0.0094	0.0225	0.0224
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.003	0.0057	0.1488
Trypanosoma brucei	sugar transporter, putative	0.0014	0.0015	0.2127
Brugia malayi	Cache domain containing protein	0.0074	0.017	0.017
Echinococcus granulosus	dnaJ subfamily B	0.0404	0.1034	0.1033
Echinococcus granulosus	biogenic amine 5HT receptor	0.009	0.0213	0.0213
Plasmodium falciparum	protein kinase 7	0.0286	0.0726	0.6542
Schistosoma mansoni	nAChR subunit	0.0086	0.0204	0.02
Loa Loa (eye worm)	ACC-1 protein	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Onchocerca volvulus		0.009	0.0213	0.1257
Schistosoma mansoni	ran	0.0026	0.0045	0.0041
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	hypothetical protein	0.009	0.0213	0.021
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0043	0.0209
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.0135	0.0131
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0178	0.0442	0.0441
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0004	0.0003
Echinococcus granulosus	neuropeptide receptor	0.009	0.0213	0.0213
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0004	0.0003
Mycobacterium leprae	ATP-dependent Clp protease proteolytic subunit 1	0.0033	0.0063	0.1771
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Brugia malayi	Eukaryotic aspartyl protease family protein	0.0017	0.0022	0.0021
Echinococcus granulosus	serotonin receptor	0.009	0.0213	0.0213
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.006	0.8107
Onchocerca volvulus		0.0086	0.0204	0.1198
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.009	0.0213	0.021
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Schistosoma mansoni	neuropeptide F-like receptor	0.009	0.0213	0.021
Schistosoma mansoni	neuropeptide F-like receptor	0.009	0.0213	0.021
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.065	0.1676	0.1676
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0031	0.0059	0.0058
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0031	0.0059	0.0404
Onchocerca volvulus		0.0178	0.0442	0.2627
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0014	0.0015	0.0014
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0178	0.0442	0.0442
Brugia malayi	Melatonin receptor type 1A	0.009	0.0213	0.0213
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	histamine h1 receptor	0.009	0.0213	0.021
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Echinococcus multilocularis	solute carrier family 22	0.0014	0.0015	0.0014
Trypanosoma cruzi	hexose transporter	0.0031	0.006	0.8107
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.3835	1	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.009	0.0213	0.021
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	1
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Echinococcus granulosus	BC026374 protein S09 family	0.0648	0.1671	0.1671
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0178	0.0442	0.0441
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0178	0.0442	0.0442
Echinococcus granulosus	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus		0.0014	0.0015	0.0067
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0178	0.0442	0.0442
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0031	0.0059	0.0058
Echinococcus granulosus	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0071	0.007
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.001	0.0004	0.0003
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0178	0.0442	0.0442
Schistosoma mansoni	sugar transporter	0.0014	0.0015	0.0011
Echinococcus multilocularis	dro:myosuppressin receptor	0.009	0.0213	0.0213
Schistosoma mansoni	protein kinase	0.0031	0.0059	0.0055
Echinococcus granulosus	transient receptor potential ion channel A	0.0093	0.022	0.0219
Schistosoma mansoni	transient receptor potential channel	0.0063	0.0143	0.014
Schistosoma mansoni	glucose transport protein	0.0101	0.0243	0.0239
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Brugia malayi	hypothetical protein	0.0086	0.0204	0.0203
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0026	0.0045	0.0418
Brugia malayi	Carboxylesterase family protein	0.0648	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Entamoeba histolytica	Ran family GTPase	0.0026	0.0045	0.0438
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.003	0.0057	0.0057
Loa Loa (eye worm)	GABA receptor subunit	0.0091	0.0216	0.0215
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0035	0.007	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.009	0.0213	0.0213
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0648	0.1671	0.1671
Schistosoma mansoni	glucose transporter	0.0014	0.0015	0.0011
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	1
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0031	0.0059	0.0404
Schistosoma mansoni	nAChR subunit	0.0178	0.0442	0.0438
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Loa Loa (eye worm)	acetylcholine receptor protein	0.0086	0.0204	0.0203
Schistosoma mansoni	neuropeptide receptor	0.009	0.0213	0.021
Echinococcus granulosus	g-protein coupled receptor	0.009	0.0213	0.0213
Brugia malayi	Importin beta-1 subunit	0.0035	0.0069	0.0068
Schistosoma mansoni	sugar transporter	0.0014	0.0015	0.0011
Brugia malayi	hypothetical protein	0.0014	0.0015	0.0015
Echinococcus multilocularis	rhodopsin orphan GPCR	0.009	0.0213	0.0213
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0178	0.0442	0.0441
Plasmodium falciparum	plasmepsin III	0.0017	0.0022	0.0061
Brugia malayi	nuclear hormone receptor	0.001	0.0004	0.0003
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0026	0.0045	0.0274
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Onchocerca volvulus		0.0648	0.1671	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Loa Loa (eye worm)	sugar transporter	0.0014	0.0015	0.0014
Echinococcus multilocularis	snurportin 1	0.0372	0.0949	0.0948
Brugia malayi	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	fmrfamide receptor	0.009	0.0213	0.0213
Schistosoma mansoni	neurotransmitter gated ion channel	0.0091	0.0216	0.0212
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0031	0.0059	0.0617
Onchocerca volvulus		0.009	0.0213	0.1257
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.001	0.0004	0.0003
Brugia malayi	Cam kinase protein 1	0.0031	0.0059	0.0058
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0178	0.0442	0.0442
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0086	0.0204	0.0203
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0086	0.0204	0.0203
Brugia malayi	RE15519p	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0216	0.0215
Plasmodium falciparum	plasmepsin IX	0.0017	0.0022	0.0061
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0178	0.0442	0.0442
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0178	0.0442	0.0442
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	0.1313
Schistosoma mansoni	transient receptor potential channel	0.0063	0.0143	0.014
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.003	0.0057	0.0053
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	dnaJ subfamily B	0.0404	0.1034	0.1033
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0004	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0204	0.0203
Plasmodium vivax	aspartyl protease, putative	0.0017	0.0022	0.005
Echinococcus granulosus	glycine receptor subunit beta	0.0178	0.0442	0.0441
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Entamoeba histolytica	protein kinase, putative	0.0031	0.0059	0.1227
Brugia malayi	G-protein coupled receptor	0.009	0.0213	0.0213
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0043	0.6085
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.006	0.0271
Brugia malayi	hypothetical protein	0.0017	0.0022	0.0021
Onchocerca volvulus		0.0178	0.0442	0.2627
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0648	0.1671	0.1668
Echinococcus granulosus	General substrate transporter	0.0087	0.0205	0.0205
Echinococcus multilocularis	G-protein coupled receptor, putative	0.009	0.0213	0.0213
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0023	0.0037	0.5237
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Brugia malayi	hypothetical protein	0.0014	0.0015	0.0015
Schistosoma mansoni	biogenic amine (5HT) receptor	0.009	0.0213	0.021
Loa Loa (eye worm)	carboxylesterase	0.3835	1	1
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0028	0.0052	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Chlamydia trachomatis	lysine--tRNA ligase	0.0023	0.0037	0.142
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.065	0.1676	0.1676
Brugia malayi	RNA, U transporter 1	0.0099	0.0236	0.0236
Loa Loa (eye worm)	hypothetical protein	0.3835	1	1
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0178	0.0442	0.0441
Brugia malayi	Major Facilitator Superfamily protein	0.0014	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0096	0.0228	0.0228
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0017	0.0022	0.0018
Plasmodium falciparum	plasmepsin V	0.0017	0.0022	0.0061
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0648	0.1671	1
Schistosoma mansoni	glucose transport protein	0.0101	0.0243	0.0239
Echinococcus granulosus	g protein coupled receptor	0.009	0.0213	0.0213
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0086	0.0204	0.0203
Brugia malayi	Dopamine receptor protein 2	0.009	0.0213	0.0213
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0031	0.0059	0.0404
Brugia malayi	larval opioid receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	LGC-31 protein	0.0178	0.0442	0.0441
Schistosoma mansoni	cathepsin D (A01 family)	0.0017	0.0022	0.0018
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	dihydropyridine-sensitive l-type calcium channel	0.016	0.0395	0.0391
Echinococcus granulosus	tm gpcr rhodopsin	0.009	0.0213	0.0213
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Brugia malayi	Sugar transporter family protein	0.0101	0.0243	0.0242
Echinococcus multilocularis	acetylcholinesterase	0.3835	1	1
Echinococcus multilocularis	short transient receptor potential channel 6	0.0063	0.0143	0.0143
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0091	0.0216	0.0216
Brugia malayi	Dopamine receptor protein 1	0.009	0.0213	0.0213
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.001	0.0004	0.0003
Leishmania major	glucose transporter, lmgt1	0.0031	0.006	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0026	0.0045	0.0044
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0178	0.0442	0.0438
Schistosoma mansoni	hypothetical protein	0.0404	0.1034	0.103
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0178	0.0442	0.0441
Echinococcus multilocularis	orexin receptor type 2	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0014	0.0015	0.2127
Onchocerca volvulus		0.0014	0.0015	0.0067
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0178	0.0442	0.0438
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0063	0.0062
Echinococcus multilocularis	serotonin receptor	0.009	0.0213	0.0213
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Trypanosoma brucei	glucose transporter 1E	0.0031	0.006	0.851
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Echinococcus multilocularis	neuropeptide receptor	0.009	0.0213	0.0213
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0178	0.0442	0.0441
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.001	0.0004	0.0003
Entamoeba histolytica	hypothetical protein	0.0091	0.0216	1
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0101	0.0243	0.0242
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Schistosoma mansoni	amine GPCR	0.009	0.0213	0.021
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.009	0.0213	0.0213
Schistosoma mansoni	acetylcholinesterase	0.0648	0.1671	0.1668
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.009	0.0213	0.0213
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.003	0.0057	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0074	0.017	0.017
Brugia malayi	hypothetical protein	0.0017	0.0022	0.0021
Schistosoma mansoni	hypothetical protein	0.009	0.0213	0.021
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.0648	0.1671	1
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0101	0.0243	0.0242
Echinococcus granulosus	peptide allatostatin:somatostatin	0.009	0.0213	0.0213
Plasmodium falciparum	plasmepsin VI	0.0017	0.0022	0.0061
Plasmodium vivax	hexose transporter	0.0101	0.0243	0.1708
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.0037	0.0186
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0178	0.0442	0.0442
Onchocerca volvulus		0.009	0.0213	0.1257
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0023	0.0037	0.0132
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.009	0.0213	0.0213
Echinococcus granulosus	peptidase Clp S14 family	0.0062	0.0139	0.0139
Echinococcus granulosus	fmrfamide receptor	0.009	0.0213	0.0213
Echinococcus granulosus	7TM GPCR rhodopsin	0.009	0.0213	0.0213
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0094	0.0225	0.1313
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0178	0.0442	0.0441
Echinococcus granulosus	acetylcholinesterase	0.3835	1	1
Echinococcus multilocularis	g protein coupled receptor	0.009	0.0213	0.0213
Schistosoma mansoni	importin beta-1	0.0035	0.0069	0.0065
Loa Loa (eye worm)	hypothetical protein	0.009	0.0213	0.0213
Plasmodium vivax	plasmepsin IV, putative	0.0017	0.0022	0.005
Echinococcus granulosus	neuropeptide receptor	0.009	0.0213	0.0213
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0178	0.0442	0.0441
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0031	0.0059	0.0058
Toxoplasma gondii	aspartyl protease ASP3	0.0017	0.0022	0.0094
Loa Loa (eye worm)	hypothetical protein	0.0178	0.0442	0.0441
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0648	0.1671	0.1671
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.009	0.0213	0.021
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.009	0.0213	0.021
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0015	0.0014
Onchocerca volvulus		0.009	0.0213	0.1257
Trypanosoma brucei	glucose transporter, putative	0.0031	0.006	0.851
Schistosoma mansoni	sugar transporter	0.0014	0.0015	0.0011
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.006	0.0271
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.009	0.0213	0.021
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.001	0.0004	0.0003
Onchocerca volvulus		0.0014	0.0015	0.0067
Echinococcus granulosus	neuropeptide Y receptor	0.009	0.0213	0.0213

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 832237