Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0282 | 0.0028 | 0.5 | |
Onchocerca volvulus | 0.0282 | 0.0028 | 0.5 | |
Onchocerca volvulus | 0.0282 | 0.0028 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0282 | 0.0028 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1667 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0282 | 0.0028 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1667 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1667 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1667 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 0.0028 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0282 | 0.0028 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1667 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1667 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0282 | 0.0028 | 0.5 |
Onchocerca volvulus | 0.0282 | 0.0028 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.1667 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0282 | 0.0028 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1667 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1667 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1667 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1667 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0282 | 0.0028 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1667 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.