Detailed information for compound 832593

Basic information

Technical information
  • TDR Targets ID: 832593
  • Name: 2-(2-chlorophenoxy)-N-[[3-(4-methoxyphenyl)-1 ,2,4-oxadiazol-5-yl]methyl]acetamide
  • MW: 373.79 | Formula: C18H16ClN3O4
  • H donors: 1 H acceptors: 3 LogP: 3.25 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1noc(n1)CNC(=O)COc1ccccc1Cl
  • InChi: 1S/C18H16ClN3O4/c1-24-13-8-6-12(7-9-13)18-21-17(26-22-18)10-20-16(23)11-25-15-5-3-2-4-14(15)19/h2-9H,10-11H2,1H3,(H,20,23)
  • InChiKey: GDQCRUOWVATYEH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-chlorophenoxy)-N-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]ethanamide
  • ZINC04868003
  • STK266904

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0096 0.0294
Echinococcus granulosus cyclins 0.0017 0.0008 0.0008
Echinococcus multilocularis nervana 2 0.0462 0.2868 0.2868
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0033 0.0135
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0151 0.0204
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0091 0.0481 0.3519
Echinococcus granulosus nervana 2 0.0751 0.473 0.473
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0016 0.0011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0042 0.0042
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0151 0.0203
Loa Loa (eye worm) hypothetical protein 0.0072 0.0362 0.0764
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0513 0.1084
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0175 0.1025 0.1025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Echinococcus multilocularis serotonin transporter 0.0181 0.1064 0.1064
Loa Loa (eye worm) hypothetical protein 0.013 0.0737 0.1558
Schistosoma mansoni microtubule-associated protein tau 0.0712 0.4479 0.4479
Loa Loa (eye worm) hypothetical protein 0.0054 0.0246 0.0519
Echinococcus granulosus nuclear receptor nhr 48 0.0083 0.043 0.043
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0014 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0138 0.0942
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0024 0.0061
Echinococcus granulosus lamin 0.0027 0.0075 0.0075
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0033 0.011 0.011
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0024 0.0051
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0038 0.014 0.014
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0024 0.0051
Leishmania major cyclin 0.0041 0.0163 0.0996
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0181 0.1064 0.3431
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0051 0.0495
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.018
Echinococcus granulosus cyclin B3 1 0.0017 0.0008 0.0008
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0033 0.0033
Echinococcus granulosus cation transporting ATPase 13A1 0.0029 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0011
Brugia malayi gamma-secretase subunit aph-1 0.0272 0.1649 0.533
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0073 0.0365 0.2633
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0051 0.0228 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Schistosoma mansoni bromodomain containing protein 0.0064 0.0313 0.0312
Onchocerca volvulus 0.0031 0.0096 0.0161
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0614
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.014 0.014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0005 0.0011
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0374 0.0374
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.004 0.0153 0.1042
Brugia malayi nuclear receptor NHR-88 0.0083 0.043 0.1376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Echinococcus multilocularis dna polymerase eta 0.004 0.0158 0.0158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0091 0.0481 0.3519
Brugia malayi MH1 domain containing protein 0.0017 0.0007 0.0007
Trichomonas vaginalis cyclin B, putative 0.0041 0.0163 0.1121
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0127 0.0847
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0083 0.043 0.0429
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0127 0.0126
Schistosoma mansoni sodium/chloride dependent transporter 0.0181 0.1064 0.1063
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0138 0.0942
Leishmania major eukaryotic initiation factor 4a, putative 0.0051 0.0228 0.1495
Echinococcus multilocularis neuroglian 0.0016 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0036 0.0127 0.0722
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.1341 0.134
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0481 0.3434
Loa Loa (eye worm) solute carrier family 6 member 4 0.0181 0.1064 0.2248
Schistosoma mansoni ATPase 0.0091 0.0481 0.0481
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0029 0.0087 0.0093
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0151 0.1191
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0738 0.5452
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0042 0.021
Schistosoma mansoni netrin receptor unc5 0.002 0.0026 0.0025
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0137 0.0782 0.0782
Brugia malayi hypoxia-induced factor 1 0.0164 0.0956 0.3081
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0046 0.0046
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0029 0.0082 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.1341 0.9678
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0029 0.0082 0.0085
Brugia malayi conserved hypotetical protein 0.0083 0.043 0.1376
Brugia malayi hypothetical protein 0.0093 0.0494 0.1583
Echinococcus granulosus cyclin b3 0.0017 0.0008 0.0008
Echinococcus granulosus heat shock protein 90 0.0037 0.0135 0.0135
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0016 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0138 0.0932
Echinococcus multilocularis cyclin B 0.0041 0.0163 0.0163
Trypanosoma brucei Aph-1 protein, putative 0.0106 0.0581 0.4261
Trypanosoma brucei mitotic cyclin 6 0.0041 0.0163 0.1108
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0016 0.0011
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0024 0.0061
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0206 0.1225 0.3954
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0021 0.0033 0.0135
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0016 0.0011
Echinococcus granulosus copper transporting ATPase 1 0.0029 0.0082 0.0082
Echinococcus granulosus gamma secretase subunit aph 1 0.0272 0.1649 0.1649
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0096 0.0095
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0175 0.1025 0.2168
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0175 0.1025 0.3307
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Plasmodium falciparum eukaryotic initiation factor 4A 0.0051 0.0228 0.4646
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0158 0.1078
Loa Loa (eye worm) fibroinase 0.0036 0.0127 0.0268
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0033 0.0033
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0462 0.2868 0.2868
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0158 0.0215
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0175 0.1025 0.1025
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0016 0.0087
Echinococcus multilocularis importin subunit beta 1 0.003 0.0094 0.0094
Echinococcus granulosus FTZ F1 alpha 0.0175 0.1025 0.1025
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0319 0.1016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0175 0.1025 0.3307
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0738 0.5389
Loa Loa (eye worm) hypothetical protein 0.0089 0.0472 0.0998
Trypanosoma cruzi CYC2-like cyclin, putative 0.0041 0.0163 0.1118
Schistosoma mansoni retinoic acid receptor RXR 0.0277 0.168 0.168
Schistosoma mansoni hypothetical protein 0.0021 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0086 0.0086
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0042 0.02
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0127 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0033 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0221 0.132 0.132
Mycobacterium ulcerans beta-lactamase 0.0224 0.1341 0.2247
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0096 0.0096
Echinococcus multilocularis snurportin 1 0.0325 0.1991 0.1991
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Onchocerca volvulus 0.005 0.0218 0.0421
Loa Loa (eye worm) ctsf protein 0.0036 0.0127 0.0268
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0158 0.1068
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0158 0.1068
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0091 0.0481 0.343
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0158 0.1078
Brugia malayi ecdysteroid receptor 0.0175 0.1025 0.3307
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0075 0.0158
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0138 0.0807
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Echinococcus multilocularis zinc finger protein 0.002 0.0026 0.0026
Onchocerca volvulus Tyrosine kinase homolog 0.0193 0.1138 0.2373
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0158 0.0157
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0151 0.1299
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0614
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0091 0.0481 0.3512
Brugia malayi Nuclear hormone receptor E75 0.0083 0.043 0.1376
Schistosoma mansoni zinc finger protein 0.0083 0.043 0.0429
Brugia malayi hypothetical protein 0.0152 0.0873 0.2814
Giardia lamblia Grp94/Hsp90 0.0029 0.0087 0.0655
Loa Loa (eye worm) TK protein kinase 0.0034 0.0117 0.0246
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.5467
Trichomonas vaginalis esterase, putative 0.0224 0.1341 0.9678
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Entamoeba histolytica hypothetical protein 0.0025 0.0057 0.0563
Echinococcus granulosus jun protein 0.0092 0.0488 0.0488
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0033 0.0135
Trypanosoma brucei glucosidase, putative 0.0037 0.0138 0.0922
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0751 0.473 0.473
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0272 0.1649 0.3487
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0033 0.0033
Brugia malayi Ets-domain containing protein 0.0074 0.0374 0.1196
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Onchocerca volvulus 0.0041 0.0163 0.0303
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0294
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0297 0.1807 0.3047
Brugia malayi nuclear hormone receptor family member odr-7 0.0083 0.043 0.1376
Schistosoma mansoni heat shock protein 0.0037 0.0135 0.0134
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0091 0.0481 0.0481
Echinococcus granulosus tyrosine protein kinase Lyn 0.0038 0.014 0.014
Treponema pallidum ATP-dependent RNA helicase 0.0051 0.0228 0.2036
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0051 0.0228 0.161
Trichomonas vaginalis cyclin B, putative 0.0041 0.0163 0.1121
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0175 0.1025 0.3307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0151 0.1647
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.014 0.014
Echinococcus granulosus dna polymerase kappa 0.004 0.0158 0.0158
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0005 0.0005
Toxoplasma gondii hypothetical protein 0.0031 0.0096 0.0614
Treponema pallidum sodium- and chloride- dependent transporter 0.0181 0.1064 1
Echinococcus multilocularis endoplasmin 0.0029 0.0087 0.0087
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0091 0.0481 0.0481
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0751 0.473 0.473
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0289 0.0289
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0051 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Trypanosoma cruzi P-type H+-ATPase, putative 0.0058 0.0269 0.192
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0319 0.0674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0135 0.0919
Leishmania major P-type H -ATPase, putative 0.0058 0.0269 0.1809
Schistosoma mansoni ATPase 0.0091 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0016 0.0015
Echinococcus granulosus nervana 2 0.0462 0.2868 0.2868
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0058
Brugia malayi tailless protein 0.0083 0.043 0.1376
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0319 0.0318
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0138 0.0932
Brugia malayi steroid hormone receptor 0.0175 0.1025 0.3307
Loa Loa (eye worm) RNA binding protein 0.0065 0.0319 0.0674
Brugia malayi nuclear hormone receptor 0.0175 0.1025 0.3307
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0127 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Plasmodium vivax heat shock protein 86, putative 0.0037 0.0135 0.0898
Toxoplasma gondii exonuclease III APE 0.0039 0.0151 0.1028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Echinococcus multilocularis smad 0.0017 0.0007 0.0007
Echinococcus granulosus lamin dm0 0.0027 0.0075 0.0075
Echinococcus granulosus GPCR family 2 0.0017 0.0005 0.0005
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.004 0.0153 0.0323
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0024 0.0023
Schistosoma mansoni hypothetical protein 0.0106 0.0578 0.0578
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.0135 0.0908
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0331 0.0331
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0135 0.0898
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0082 0.051
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0496 0.309 0.6532
Echinococcus granulosus dna polymerase eta 0.004 0.0158 0.0158
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0051 0.0228 0.1601
Leishmania major DNA polymerase kappa, putative 0.004 0.0158 0.0955
Brugia malayi MH2 domain containing protein 0.0017 0.0007 0.0007
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.1469 0.1469
Brugia malayi Steroid receptor seven-up type 2 0.0175 0.1025 0.3307
Brugia malayi orphan nuclear receptor NR2E1 0.0083 0.043 0.1376
Brugia malayi Pre-SET motif family protein 0.0203 0.1205 0.3888
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0331 0.1055
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0073 0.0365 0.0365
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0024 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0094 0.059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0082 0.0174
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.3434
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0016 0.0087
Entamoeba histolytica protein kinase, putative 0.003 0.0092 0.0969
Brugia malayi follicle stimulating hormone receptor 0.0496 0.309 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0138 0.0942
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0206 0.1225 0.259
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0151 0.1034
Trichomonas vaginalis cyclin B, putative 0.0041 0.0163 0.1121
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0124 0.0694 0.5125
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0738 0.0738
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0462 0.2868 0.2868
Loa Loa (eye worm) hypothetical protein 0.0221 0.132 0.2791
Schistosoma mansoni phosphoserine phosphatase 0.0018 0.0015 0.0014
Mycobacterium ulcerans esterase/lipase LipP 0.0224 0.1341 0.2247
Entamoeba histolytica hypothetical protein 0.0152 0.0873 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.077 0.5696
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0158
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0331 0.2375
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0158 0.0493
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0029 0.0082 0.0499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0051 0.0311
Brugia malayi Membrane calcium atpase protein 3 0.0073 0.0365 0.1165
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.098 0.3159
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0138 0.1499
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0029 0.0082 0.0081
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0091 0.0481 0.3512
Onchocerca volvulus 0.0027 0.0075 0.0116
Loa Loa (eye worm) nuclear hormone receptor 0.0083 0.043 0.0909
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0175 0.1025 0.1025
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.098 0.2071
Entamoeba histolytica hypothetical protein 0.002 0.0024 0.0182
Plasmodium falciparum importin beta, putative 0.003 0.0094 0.1814
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0374 0.0791
Echinococcus multilocularis heat shock protein 90 0.0037 0.0135 0.0135
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0138 0.043
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0751 0.473 0.473
Schistosoma mansoni ran 0.0022 0.0042 0.0042
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0127 0.0227
Trypanosoma cruzi P-type H+-ATPase, putative 0.0058 0.0269 0.192
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0331 0.2279
Trypanosoma cruzi Aph-1 protein, putative 0.0106 0.0581 0.4268
Toxoplasma gondii cathepsin CPL 0.0036 0.0127 0.0847
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0082 0.0852
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.014 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Echinococcus multilocularis nervana 2 0.0751 0.473 0.473
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0033 0.0125
Schistosoma mansoni endoplasmin 0.0037 0.0135 0.0134
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0203 0.1204 0.1203
Brugia malayi Cyclin, N-terminal domain containing protein 0.0041 0.0163 0.051
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.1503 0.3176
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0117 0.0117
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0051 0.0228 0.161
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0093 0.0494 0.0494
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0135 0.0898
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0127 0.0268
Plasmodium falciparum calcium-transporting ATPase 0.0073 0.0365 0.7537
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0023
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0331 0.2384
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0237 0.0751
Brugia malayi bZIP transcription factor family protein 0.0092 0.0488 0.1565
Brugia malayi Pre-SET motif family protein 0.0029 0.0086 0.026
Brugia malayi nuclear receptor RXR 0.0093 0.0494 0.1583
Onchocerca volvulus 0.0083 0.043 0.087
Echinococcus granulosus cyclins 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0231 0.1386 0.29
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0029 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.014 0.014
Onchocerca volvulus 0.0224 0.1341 0.2804
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0051 0.0227 0.2523
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0082 0.0852
Loa Loa (eye worm) hypothetical protein 0.0093 0.0494 0.1044
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.098 0.098
Schistosoma mansoni amine oxidase 0.0021 0.0033 0.0032
Echinococcus multilocularis cyclin B3 1 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0091 0.0481 0.0771
Brugia malayi heat shock protein 90 0.0037 0.0135 0.042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0082 0.0174
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0051 0.0228 0.0227
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0138 0.0942
Loa Loa (eye worm) hypothetical protein 0.0043 0.0178 0.0376
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0033 0.0509
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0007 0.0016
Mycobacterium tuberculosis Conserved protein 0.0224 0.1341 0.144
Trypanosoma cruzi heat shock protein 90, putative 0.0029 0.0087 0.0544
Brugia malayi Nuclear hormone receptor E75 0.0083 0.043 0.1376
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0024 0.0024
Trichomonas vaginalis cyclins, putative 0.0041 0.0163 0.1121
Loa Loa (eye worm) cysteine protease 0.0036 0.0127 0.0268
Schistosoma mansoni hypothetical protein 0.157 1 1
Trypanosoma brucei calcium-translocating P-type ATPase 0.0073 0.0365 0.2633
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0135 0.0908
Schistosoma mansoni regulator of G protein signaling 0.002 0.0024 0.0023
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0051 0.0228 0.254
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.004 0.0153 0.1042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0175 0.1025 0.3307
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0007 0.0007
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0221 0.132 0.2212
Brugia malayi hypothetical protein 0.002 0.0024 0.0061
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0224 0.1341 0.144
Leishmania major eukaryotic initiation factor 4a, putative 0.0051 0.0228 0.1495
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0513 0.0512
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0073 0.0365 0.0365
Leishmania major calcium-transporting ATPase, putative 0.0073 0.0365 0.254
Loa Loa (eye worm) hypothetical protein 0.0118 0.0654 0.1384
Brugia malayi beta-lactamase family protein 0.0224 0.1341 0.4329
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Echinococcus granulosus importin subunit beta 1 0.003 0.0094 0.0094
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0175 0.1025 0.1025
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0096 0.0096
Schistosoma mansoni DNA polymerase eta 0.004 0.0158 0.0157
Echinococcus multilocularis ecdysone induced protein 78C 0.0175 0.1025 0.1025
Trichomonas vaginalis cyclins, putative 0.0041 0.0163 0.1121
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Trypanosoma cruzi Aph-1 protein, putative 0.0106 0.0581 0.4268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0175 0.1025 0.1025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0151 0.0151
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0033 0.0509
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0513 0.0513
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0175 0.1025 0.2168
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0007 0.0016
Brugia malayi Bromodomain containing protein 0.0039 0.0149 0.0466
Schistosoma mansoni transmemberane protein 0.0751 0.473 0.473
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0043 0.0178 0.1231
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0083 0.043 0.043
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0127 0.2506
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Plasmodium vivax vivapain-2 0.0036 0.0127 0.0837
Loa Loa (eye worm) heat shock protein 90 0.0037 0.0135 0.0285
Giardia lamblia G2/mitotic-specific cyclin B 0.0041 0.0163 0.1292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Loa Loa (eye worm) hypothetical protein 0.0178 0.1045 0.2208
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0127 0.0861
Schistosoma mansoni single-minded 0.0053 0.024 0.0239
Loa Loa (eye worm) hypothetical protein 0.0039 0.015 0.0316
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0031 0.0096 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0051 0.0311
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0374 0.0374
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0151 0.1018
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0007 0.0007
Schistosoma mansoni alpha glucosidase 0.0037 0.0138 0.0137
Echinococcus multilocularis cation transporting ATPase 13A1 0.0029 0.0082 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0175 0.1025 0.3307
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0083 0.043 0.0909
Echinococcus granulosus expressed protein 0.0381 0.2353 0.2353
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0017 0.0006 0.0006
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0073 0.0365 0.2589
Echinococcus granulosus serotonin transporter 0.0181 0.1064 0.1064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.018
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0029 0.0082 0.0055
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0138 0.0932
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0055
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0073 0.0365 0.0364
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0033 0.011 0.0721
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0751 0.473 0.473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0175 0.1025 0.2168
Onchocerca volvulus 0.0021 0.0033 0.0027
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0043 0.0254
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.077 0.5696
Trypanosoma cruzi cyclin, putative 0.0041 0.0163 0.1118
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Loa Loa (eye worm) DR-78 0.0083 0.043 0.0909
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0151 0.0472
Schistosoma mansoni cell adhesion molecule 0.0017 0.0006 0.0006
Onchocerca volvulus 0.0036 0.0127 0.0227
Echinococcus multilocularis dna polymerase kappa 0.004 0.0158 0.0158
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0481 0.3434
Loa Loa (eye worm) hypothetical protein 0.0093 0.0494 0.1044
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0152 0.0873 0.0873
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus granulosus tyrosine protein kinase Src42A 0.0033 0.011 0.011
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.02
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0246 0.0245
Echinococcus granulosus axis inhibition protein axin 0.002 0.0024 0.0024
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0029 0.0087 0.0087
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0091 0.0481 0.0481
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0138 0.0138
Trypanosoma cruzi cyclin, putative 0.0041 0.0163 0.1118
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0007 0.0007
Mycobacterium tuberculosis Probable esterase LipL 0.0224 0.1341 0.144
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0294
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0024 0.0024
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0319 0.0319
Leishmania major cathepsin L-like protease 0.0036 0.0127 0.0722
Entamoeba histolytica Ran family GTPase 0.0022 0.0042 0.0393
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0038 0.0176
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.098 0.098
Echinococcus multilocularis nervana 2 0.0462 0.2868 0.2868
Trichomonas vaginalis cyclins, putative 0.0041 0.0163 0.1121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0175 0.1025 0.2168
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0127 0.0127
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0149 0.0149
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0197 0.0197
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0029 0.0082 0.0085
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0138 0.0138
Trypanosoma cruzi cation-transporting ATPase, putative 0.0029 0.0082 0.051
Brugia malayi Nuclear hormone receptor-like 1 0.0093 0.0494 0.1583
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0091 0.0481 0.5467
Loa Loa (eye worm) hypothetical protein 0.0024 0.0051 0.0109
Brugia malayi Fli-1 protein 0.0225 0.1344 0.4339
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0051 0.0228 0.0227
Trypanosoma brucei calcium-transporting ATPase, putative 0.0043 0.0178 0.1221
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0175 0.1025 0.1025
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0051 0.0228 0.1596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Leishmania major DNA polymerase eta, putative 0.004 0.0158 0.0955
Loa Loa (eye worm) nuclear receptor NHR-67 0.0083 0.043 0.0909
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Schistosoma mansoni cyclin B 0.0041 0.0163 0.0162
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0096 0.0095
Brugia malayi protein-tyrosine kinase 0.0034 0.0117 0.036
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0333
Brugia malayi E1-E2 ATPase family protein 0.0029 0.0082 0.0249
Loa Loa (eye worm) hypothetical protein 0.0024 0.0053 0.0111
Mycobacterium tuberculosis Conserved protein 0.0224 0.1341 0.144
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0024 0.0061
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0024 0.0051
Brugia malayi RNA binding protein 0.0065 0.0319 0.1016
Echinococcus granulosus cation transporting ATPase 13A3 0.0029 0.0082 0.0082
Schistosoma mansoni regulator of G protein signaling 0.002 0.0024 0.0023
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0038 0.014 0.014
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0481 0.3434
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0038 0.014 0.014
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0029 0.0082 0.0852
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0738 0.1211
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0051 0.0109
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0751 0.473 0.473
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0331 0.0699
Loa Loa (eye worm) hypothetical protein 0.004 0.0153 0.0323
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0158 0.0138
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0192 0.1133 0.3656
Schistosoma mansoni nuclear hormone receptor 0.0083 0.043 0.0429
Schistosoma mansoni thyroid hormone receptor 0.0313 0.191 0.1909
Echinococcus granulosus cathepsin L 0.0018 0.0016 0.0016
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0513 0.1645
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Loa Loa (eye worm) RGS-3 protein 0.002 0.0024 0.0051
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0738 0.0737
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Leishmania major importin beta-1 subunit, putative 0.0025 0.0057 0.0188
Trypanosoma brucei unspecified product 0.004 0.0158 0.1068
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0158 0.0333
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0024 0.0024
Loa Loa (eye worm) serotonin transporter b 0.0181 0.1064 0.2248
Schistosoma mansoni axis inhibition protein axin 0.002 0.0024 0.0023
Treponema pallidum heat shock protein 90 0.0029 0.0087 0.0688
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Giardia lamblia DINP protein human, muc B family 0.004 0.0158 0.1247
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0091 0.0481 0.3519
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0237 0.0751
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0583 0.4289
Echinococcus granulosus Nuclear hormone receptor HR96 0.0083 0.043 0.043
Schistosoma mansoni tyrosine kinase 0.0038 0.014 0.0139
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0024 0.0024
Mycobacterium tuberculosis Conserved protein 0.0224 0.1341 0.144
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0024 0.0024
Plasmodium falciparum endoplasmin, putative 0.0023 0.0043 0.0739
Brugia malayi eukaryotic initiation factor 4A 0.0051 0.0228 0.0722
Leishmania major cathepsin L-like protease 0.0135 0.077 0.5637
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0024 0.0023
Brugia malayi PXA domain containing protein 0.002 0.0024 0.0061
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0029 0.0082 0.0535
Leishmania major calcium-translocating P-type ATPase 0.0091 0.0481 0.343
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0091 0.0481 0.3519
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0057 0.0353
Brugia malayi nuclear receptor RXR 0.0083 0.043 0.1376
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0158 0.1082
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0127 0.0722
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0175 0.1025 0.1025
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0158 0.1723
Schistosoma mansoni hypothetical protein 0.0152 0.0873 0.0873
Mycobacterium leprae Probable lipase LipE 0.0224 0.1341 0.2247
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0093 0.0494 0.0494
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0415 0.0415
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.077 0.5696
Entamoeba histolytica cysteine protease, putative 0.0036 0.0127 0.137
Echinococcus granulosus tumor protein p63 0.0369 0.2272 0.2272
Brugia malayi hypothetical protein 0.0244 0.1469 0.4744
Leishmania major cathepsin L-like protease 0.0135 0.077 0.5637
Onchocerca volvulus 0.0036 0.0127 0.0227
Brugia malayi beta-lactamase 0.0224 0.1341 0.4329
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0135 0.1462
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Onchocerca volvulus 0.0031 0.0096 0.0161
Brugia malayi E1-E2 ATPase family protein 0.0058 0.0269 0.0855
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0175 0.1025 0.3307
Trichomonas vaginalis cation-transporting ATPase, putative 0.0058 0.0269 0.1894
Brugia malayi Nuclear hormone receptor-like 1 0.0175 0.1025 0.3307
Schistosoma mansoni steroid hormone receptor ad4bp 0.0175 0.1025 0.1025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0513 0.0512
Echinococcus granulosus cathepsin l1 0.0024 0.0051 0.0051
Schistosoma mansoni smad 0.0017 0.0007 0.0007
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0082 0.051
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Echinococcus granulosus tyrosine kinase 0.0034 0.0117 0.0117
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Onchocerca volvulus 0.0221 0.132 0.276
Brugia malayi MH2 domain containing protein 0.0249 0.1503 0.4854
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0158 0.1078
Onchocerca volvulus 0.0175 0.1025 0.2134
Brugia malayi Bromodomain containing protein 0.0076 0.039 0.1245
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0175 0.1025 0.3307
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0073 0.0365 0.2641
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.1341 0.9678
Echinococcus granulosus tyrosine protein kinase HCK 0.003 0.0092 0.0092
Loa Loa (eye worm) fli-1 protein 0.0225 0.1344 0.2841
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0127 0.0127
Mycobacterium ulcerans proteasome PrcA 0.0925 0.5854 1
Echinococcus granulosus ecdysone induced protein 78C 0.0175 0.1025 0.1025
Echinococcus granulosus cyclins 0.0017 0.0008 0.0008
Echinococcus multilocularis thyroid hormone receptor alpha 0.0313 0.191 0.191
Echinococcus granulosus nervana 2 0.0751 0.473 0.473
Toxoplasma gondii heat shock protein HSP90 0.0037 0.0135 0.0908
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0175 0.1025 0.1025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0175 0.1025 0.3307
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.0135 0.0908
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0224 0.1341 0.144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Brugia malayi hypothetical protein 0.0072 0.0361 0.1154
Echinococcus multilocularis tyrosine protein kinase HCK 0.003 0.0092 0.0092
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0751 0.473 0.473
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0175 0.1025 0.3307
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0289 0.0289
Brugia malayi hypothetical protein 0.002 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0165 0.0349
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0091 0.0481 0.343
Schistosoma mansoni hypothetical protein 0.0137 0.0782 0.0782
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0138 0.0942
Trypanosoma brucei unspecified product 0.0028 0.0077 0.046
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0086 0.0085
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0152 0.0873 0.0873
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0043 0.0178 0.0376
Schistosoma mansoni hypothetical protein 0.157 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0175 0.1025 0.2168
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0083 0.043 0.043
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0192 0.1133 0.2395
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0513 0.0513
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.0135 0.0908
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0092 0.0488 0.0488
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0135 0.0908
Onchocerca volvulus 0.0036 0.0127 0.0227
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0091 0.0481 1
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0029 0.0082 0.051
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0096 0.0095
Brugia malayi hypothetical protein 0.0093 0.0494 0.1583
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0151 0.013
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Onchocerca volvulus 0.0224 0.1341 0.2804
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0158 0.0215
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0224 0.1341 0.2834
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Schistosoma mansoni ets-related 0.0225 0.1344 0.1343
Brugia malayi Smad1 0.0017 0.0007 0.0007
Echinococcus granulosus single minded 2 0.0039 0.0151 0.0151
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1205 0.2546
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0073 0.0365 0.2981
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0029 0.0082 0.0535
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0029 0.0082 0.0085
Trichomonas vaginalis ran, putative 0.0022 0.0042 0.0247
Echinococcus granulosus intermediate filament protein 0.0027 0.0075 0.0075
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0319 0.0318
Echinococcus granulosus nervana 2 0.0462 0.2868 0.2868
Loa Loa (eye worm) hypothetical protein 0.0046 0.0197 0.0417
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0151 0.1034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0175 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.0063 0.0305 0.0645
Trypanosoma brucei P-type H+-ATPase, putative 0.0058 0.0269 0.1911
Echinococcus granulosus hypothetical protein 0.07 0.4402 0.4402
Echinococcus granulosus axis inhibition protein axin 0.002 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.0135 0.1058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0093 0.0494 0.0493
Loa Loa (eye worm) SRC-1 0.0038 0.014 0.0296
Brugia malayi TAR-binding protein 0.0065 0.0319 0.1016
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0007
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Echinococcus multilocularis cation transporting atpase worm 0.0029 0.0082 0.0082
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0057 0.0353
Schistosoma mansoni hypothetical protein 0.0074 0.0378 0.0377
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0203 0.1204 0.1204
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0029 0.0082 0.0085
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0062 0.0294 0.0288
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.021
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.004 0.0153 0.0478
Trichomonas vaginalis cyclin A, putative 0.0041 0.0163 0.1121
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Echinococcus granulosus cathepsin l1 0.0036 0.0127 0.0127
Onchocerca volvulus 0.0036 0.0127 0.0227
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0091 0.0481 0.0481
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0159 0.0921 0.1947
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0091 0.0481 0.3956
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0093 0.0494 0.1044
Entamoeba histolytica hypothetical protein 0.0152 0.0873 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0117 0.0117
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0138 0.0942
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0268
Schistosoma mansoni amine oxidase 0.0021 0.0033 0.0032
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0086 0.0535
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0082 0.0535
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0083 0.043 0.043
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0029 0.0082 0.0249
Schistosoma mansoni coup transcription factor 0.0175 0.1025 0.1025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0175 0.1025 0.2168
Toxoplasma gondii P-type ATPase PMA1 0.0058 0.0269 0.192
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0041 0.0163 0.0344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0024 0.0024
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0024 0.0024
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0175 0.1025 0.2134
Schistosoma mansoni gamma-secretase subunit aph-1 0.0272 0.1649 0.1649
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0127 0.0127
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0029 0.0082 0.0085
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0005 0.0005
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0021 0.0035 0.0417
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0319 0.0318
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0083 0.043 0.1376
Schistosoma mansoni cation-transporting ATPase 0.0029 0.0082 0.0081
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0094 0.059
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0075 0.0158
Schistosoma mansoni ran 0.0022 0.0042 0.0042
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0051 0.0228 0.161
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0029 0.0082 0.0082
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Toxoplasma gondii hypothetical protein 0.0031 0.0096 0.0614
Onchocerca volvulus 0.0027 0.0075 0.0116
Plasmodium vivax SET domain protein, putative 0.0029 0.0086 0.0525
Echinococcus granulosus cyclins 0.0017 0.0008 0.0008
Leishmania major calcium motive p-type ATPase, putative 0.0073 0.0365 0.254
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0079 0.0079
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0192 0.1133 0.1891
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0718
Loa Loa (eye worm) beta-lactamase 0.0224 0.1341 0.2834
Leishmania major proton motive ATPase, putative 0.0029 0.0082 0.038
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0082 0.0081
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0175 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.0093 0.0494 0.1044
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0042 0.0042
Schistosoma mansoni gabp alpha 0.0074 0.0374 0.0374
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0092 0.0488 0.0488
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0319 0.0318
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0151 0.1018
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0051 0.0228 0.0442
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0751 0.473 0.473
Onchocerca volvulus 0.0181 0.1064 0.2216
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0024 0.0114
Schistosoma mansoni hypothetical protein 0.0325 0.1991 0.1991
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0127 0.0127
Echinococcus multilocularis heat shock protein 90 0.0029 0.0087 0.0087
Mycobacterium ulcerans heat shock protein 90 0.0029 0.0087 0.0093
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0738 0.1211
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0117 0.0117
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0203
Echinococcus multilocularis netrin receptor unc 5 0.002 0.0026 0.0026
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Plasmodium vivax amine transporter, putative 0.0031 0.0096 0.0604
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0224 0.1341 0.144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.098 0.098
Echinococcus multilocularis tumor protein p63 0.0369 0.2272 0.2272
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0151 1
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0016 0.0087
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0024 0.0061
Brugia malayi nuclear receptor NHR-67 0.0083 0.043 0.1376
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0276 0.1672 0.1805
Schistosoma mansoni hypothetical protein 0.005 0.0218 0.0218
Brugia malayi calcium ATPase 0.004 0.0153 0.0478
Brugia malayi Protein kinase domain containing protein 0.0118 0.0654 0.2104
Trypanosoma brucei unspecified product 0.0028 0.0077 0.046
Trichomonas vaginalis cyclin B, putative 0.0041 0.0163 0.1121
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0038 0.014 0.014
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0158 0.1068
Loa Loa (eye worm) E1-E2 ATPase 0.0058 0.0269 0.0569
Brugia malayi MH2 domain containing protein 0.0017 0.0007 0.0007
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0033 0.0088
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0127 0.137
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.077 0.5696
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0051 0.0109
Loa Loa (eye worm) hypothetical protein 0.0093 0.0494 0.1044
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0041 0.0163 0.0996
Echinococcus granulosus Nuclear hormone receptor HR96 0.0083 0.043 0.043
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0127 0.0227
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0175 0.1025 0.1025
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0925 0.5854 1
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0158 0.1082
Echinococcus multilocularis expressed protein 0.0381 0.2353 0.2353
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus multilocularis lamin dm0 0.0027 0.0075 0.0075
Echinococcus granulosus twitchin 0.0016 0.0001 0.0001
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0091 0.0481 0.3434
Brugia malayi hypothetical protein 0.0018 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0175 0.1025 0.1025
Schistosoma mansoni survival motor neuron protein 0.005 0.0218 0.0218
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.014 0.014
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0181 0.1064 0.2248
Schistosoma mansoni ap endonuclease 0.0039 0.0151 0.015
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0091 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0043 0.0178 0.0375
Brugia malayi calcium ATPase 0.0033 0.011 0.034
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Echinococcus granulosus microtubule associated protein 2 0.0712 0.4479 0.4479
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0073 0.0365 0.1165
Loa Loa (eye worm) hypothetical protein 0.0163 0.0949 0.2006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0014
Leishmania major cathepsin L-like protease 0.0036 0.0127 0.0722
Schistosoma mansoni cyclins 0.0017 0.0008 0.0008
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0127 0.2506
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0415 0.0415
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0016 0.0011
Loa Loa (eye worm) hypoxia-induced factor 1 0.0164 0.0956 0.202
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0158 0.1078
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0738 0.0737
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0007 0.0007
Schistosoma mansoni endoplasmin 0.0037 0.0135 0.0134
Brugia malayi Cathepsin L-like precursor 0.0024 0.0051 0.0149
Brugia malayi PXA domain containing protein 0.002 0.0024 0.0061
Echinococcus multilocularis musashi 0.0027 0.0075 0.0075
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0029 0.0082 0.0055
Trichomonas vaginalis cyclins, putative 0.0028 0.0079 0.0513
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0073 0.0365 0.0364
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0203 0.1204 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0017 0.0008 0.001
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0087 0.0568
Onchocerca volvulus 0.0036 0.0127 0.0227
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0033 0.0032
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0158 0.0138
Brugia malayi hypothetical protein 0.0031 0.0096 0.0294
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0117 0.0117
Schistosoma mansoni transcription factor LCR-F1 0.0152 0.0873 0.0873
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0513 0.0513
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0151 0.0905
Echinococcus granulosus cyclins 0.0017 0.0008 0.0008
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Schistosoma mansoni atpase class VI type 11c 0.0018 0.0015 0.0014
Brugia malayi Fibroblast growth factor family protein 0.0055 0.0253 0.0804
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.3434
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0077 0.046
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0738 0.1211
Plasmodium vivax cation transporting ATPase, putative 0.0029 0.0082 0.0499
Echinococcus granulosus eukaryotic initiation factor 4A 0.0051 0.0228 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0175 0.1025 0.3307
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0218 0.0691
Schistosoma mansoni zinc finger protein 0.002 0.0026 0.0026
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0029 0.0087 0.0414
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Echinococcus multilocularis GPCR, family 2 0.0017 0.0005 0.0005
Trypanosoma cruzi P-type H+-ATPase, putative 0.004 0.0153 0.1042
Schistosoma mansoni RAR-like nuclear receptor 0.0175 0.1025 0.1025
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0138 0.1499
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0057 0.0321
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0007 0.0007
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0096 0.0096
Schistosoma mansoni nuclear receptor nhr-48 0.0083 0.043 0.0429
Entamoeba histolytica hypothetical protein 0.0152 0.0873 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0029 0.0087 0.006
Plasmodium falciparum transporter, putative 0.0031 0.0096 0.1851
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0016 0.0034
Plasmodium vivax copper-transporting ATPase, putative 0.0029 0.0082 0.0499
Trypanosoma cruzi cyclin 6, putative 0.0041 0.0163 0.1118
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0277 0.168 0.168
Loa Loa (eye worm) hypothetical protein 0.0053 0.0237 0.0501
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0073 0.0365 0.2641
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0024 0.0024
Onchocerca volvulus 0.0036 0.0127 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0026 0.0066
Schistosoma mansoni importin beta-1 0.003 0.0094 0.0094
Brugia malayi Ets-domain containing protein 0.0074 0.0374 0.1196
Schistosoma mansoni axis inhibition protein axin 0.002 0.0024 0.0023
Onchocerca volvulus 0.0039 0.0151 0.0278
Brugia malayi PAS domain containing protein 0.0053 0.024 0.076
Onchocerca volvulus 0.0462 0.2868 0.6047
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0184 0.1085 0.1085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.001 0.001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0331 0.2384
Schistosoma mansoni tyrosine kinase 0.0038 0.014 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.043 0.043
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0151 0.0151
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0181 0.1064 0.1063
Onchocerca volvulus 0.0054 0.0246 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0175 0.1025 0.3307
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0051 0.0228 0.0228
Brugia malayi SRC-1 0.0038 0.014 0.0437
Giardia lamblia Heat shock protein HSP 90-alpha 0.0029 0.0087 0.0655
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0151
Schistosoma mansoni thyroid hormone receptor 0.0313 0.191 0.1909
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1432 0.9115 1
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0051 0.0228 0.1596
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0083 0.043 0.0429
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0016 0.0015
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0029 0.0082 0.0617
Schistosoma mansoni intermediate filament proteins 0.0027 0.0075 0.0074
Echinococcus granulosus netrin receptor unc 5 0.002 0.0026 0.0026
Brugia malayi Endoplasmin precursor 0.0037 0.0135 0.042
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0033 0.0033
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0042 0.021
Leishmania major copper-transporting ATPase-like protein, putative 0.0029 0.0082 0.038
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0016 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0086 0.0085
Brugia malayi nuclear receptor NHR-88 0.0175 0.1025 0.3307
Schistosoma mansoni nuclear hormone receptor 0.0175 0.1025 0.1025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0175 0.1025 0.1025
Echinococcus granulosus smad 0.0017 0.0007 0.0007
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0093 0.0494 0.0493
Onchocerca volvulus 0.0224 0.1341 0.2804
Brugia malayi Cathepsin L-like precursor 0.0024 0.0051 0.0149
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.5467
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.1341 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.3434
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0462 0.2868 0.2868
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0127 0.0394
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Loa Loa (eye worm) hypothetical protein 0.0181 0.1064 0.2248
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0057 0.0353
Echinococcus granulosus roundabout 2 0.002 0.0027 0.0027
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.0284
Onchocerca volvulus 0.0097 0.0524 0.1069
Echinococcus multilocularis cathepsin L 0.0018 0.0016 0.0016
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.1341 0.134
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0224 0.1341 0.2247
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0138 0.0942
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0091 0.0481 0.3519
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Onchocerca volvulus 0.0188 0.111 0.2314
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0294
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0024 0.0023
Echinococcus multilocularis jun protein 0.0092 0.0488 0.0488
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0016 0.0087
Echinococcus multilocularis conserved hypothetical protein 0.0689 0.4333 0.4333
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.004 0.0153 0.1668
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0033 0.0125
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0094 0.0601
Plasmodium falciparum heat shock protein 90 0.0037 0.0135 0.2675
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0082 0.0535
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0158 0.1068
Loa Loa (eye worm) endoplasmin 0.0037 0.0135 0.0285
Brugia malayi Cyclin, N-terminal domain containing protein 0.0041 0.0163 0.051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Brugia malayi hypothetical protein 0.0083 0.043 0.1376
Echinococcus multilocularis cysteine protease 0.0036 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0224 0.1341 0.2834
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0331 0.033
Echinococcus granulosus Na:K ATPase alpha subunit 0.0203 0.1204 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0017 0.0008 0.0008
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0046 0.0045
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0096 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0175 0.1025 0.1025
Schistosoma mansoni heat shock protein 0.0037 0.0135 0.0134
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0083 0.043 0.087
Brugia malayi SWIRM domain containing protein 0.0021 0.0033 0.0088
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0073 0.0365 0.0365
Echinococcus granulosus tar DNA binding protein 0.0065 0.0319 0.0319
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0158 0.0955
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0175 0.1025 0.1025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0197 0.0197
Brugia malayi intermediate filament protein 0.0027 0.0075 0.0225
Brugia malayi Fibroblast growth factor family protein 0.0055 0.0253 0.0804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0513 0.0513
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0138 0.0942
Chlamydia trachomatis metal transport ATPase 0.0029 0.0082 0.7825
Echinococcus granulosus tyrosine protein kinase Src64B 0.0038 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0237 0.0501
Loa Loa (eye worm) calcium ATPase 0.0051 0.0227 0.0479
Echinococcus multilocularis calcium transporting atpase 0.0073 0.0365 0.0365
Echinococcus multilocularis 0.0021 0.0033 0.0033
Plasmodium vivax vivapain-2 0.0036 0.0127 0.0837
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0018 0.0015 0.0015
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0033 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0175 0.1025 0.3307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Echinococcus granulosus cation transporting atpase worm 0.0029 0.0082 0.0082
Echinococcus multilocularis cyclin b3 0.0017 0.0008 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0138 0.0942
Onchocerca volvulus 0.0029 0.0086 0.0139
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0175 0.1025 0.1025
Echinococcus multilocularis copper transporting ATPase 1 0.0029 0.0082 0.0082
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0021 0.0033 0.0088
Echinococcus multilocularis cyclins 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0036 0.013 0.0129
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0016 0.0015
Echinococcus multilocularis nervana 2 0.0751 0.473 0.473
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.014 0.014
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0033 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Brugia malayi MH1 domain containing protein 0.0017 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.043 0.043
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0127 0.0861
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0051 0.0228 0.1838
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.014 0.014
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0127 0.0227
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Echinococcus granulosus cyclin B 0.0041 0.0163 0.0163
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0096 0.1851
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0016 0.0055
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0091 0.0481 0.1017
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.0275
Loa Loa (eye worm) hypothetical protein 0.0751 0.473 1
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0149 0.0149
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.1991 0.421
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.1469 0.1469
Schistosoma mansoni nuclear receptor 0.0083 0.043 0.0429
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Toxoplasma gondii ABC1 family protein 0.0224 0.1341 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0175 0.1025 0.2168
Echinococcus granulosus phospholipid transporting ATPase VA 0.0018 0.0015 0.0015
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0062 0.0294 0.045
Brugia malayi Importin beta-1 subunit 0.003 0.0094 0.0288
Brugia malayi cathepsin L-like precursor 0.0024 0.0051 0.0149
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0046 0.0046
Leishmania major P-type ATPase, putative 0.0073 0.0365 0.254
Brugia malayi nuclear hormone receptor 0.0083 0.043 0.1376
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0023
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0051 0.0228 0.0482
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Schistosoma mansoni ap endonuclease 0.0039 0.0151 0.015
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0297 0.1807 0.3047
Loa Loa (eye worm) cyclin domain-containing protein 0.0017 0.0008 0.0018
Plasmodium falciparum copper-transporting ATPase 0.0029 0.0082 0.1559
Brugia malayi PHD-finger family protein 0.0025 0.0061 0.0181
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0043 0.0254
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Schistosoma mansoni type V p-type atpase isoform 0.0029 0.0082 0.0081
Plasmodium vivax RNA helicase-1, putative 0.0051 0.0228 0.1601
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0038 0.014 0.014
Mycobacterium ulcerans hypothetical protein 0.0224 0.1341 0.2247
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Echinococcus granulosus neuroglian 0.0016 0.0001 0.0001
Echinococcus multilocularis roundabout 2 0.002 0.0027 0.0027
Brugia malayi Na,K-ATPase alpha subunit 0.0221 0.132 0.4262
Onchocerca volvulus 0.0036 0.0127 0.0227
Schistosoma mansoni Smad4 0.0017 0.0007 0.0007
Plasmodium vivax endoplasmin, putative 0.0037 0.0135 0.0898
Schistosoma mansoni regulator of G protein signaling 0.002 0.0024 0.0023
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0135 0.0908
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0073 0.0365 0.0364
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0096 0.0096
Onchocerca volvulus 0.0072 0.0361 0.0725
Giardia lamblia Copper-transporting P-type ATPase 0.0029 0.0082 0.0617
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0042 0.009
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0016 0.0087
Schistosoma mansoni regulator of G protein signaling 0.002 0.0024 0.0023
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0083 0.043 0.043
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0024 0.0024
Echinococcus granulosus heat shock protein 90 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0244 0.1469 0.3105
Brugia malayi nuclear hormone receptor family member nhr-6 0.0083 0.043 0.1376
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0158 0.0158
Onchocerca volvulus 0.0031 0.0096 0.0161
Loa Loa (eye worm) TK protein kinase 0.003 0.0092 0.0195
Schistosoma mansoni alpha-glucosidase 0.0145 0.0829 0.0828
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1385 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Echinococcus multilocularis cation transporting ATPase 13A3 0.0029 0.0082 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0158 0.1078
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0082 0.051
Loa Loa (eye worm) hypothetical protein 0.0751 0.473 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0096 0.0096
Trichomonas vaginalis cyclins, putative 0.0041 0.0163 0.1121
Echinococcus multilocularis Smad4 0.0017 0.0007 0.0007
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0082 0.0852
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0151 0.1028
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0029 0.0082 0.0085
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0009
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.3434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0197 0.0197
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0751 0.473 0.473
Entamoeba histolytica cyclin, putative 0.0041 0.0163 0.1785
Brugia malayi RNA, U transporter 1 0.0087 0.0456 0.146
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0051 0.0227 0.2523
Plasmodium vivax importin-beta 2, putative 0.003 0.0094 0.059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0224 0.1341 0.4329
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.0135 0.0898
Schistosoma mansoni lamin 0.0027 0.0075 0.0074
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Toxoplasma gondii P-type ATPase4, putative 0.0091 0.0481 0.3519
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0038 0.014 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0077 0.046
Brugia malayi ecdysone receptor 0.0083 0.043 0.1376
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.3434
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0462 0.2868 0.2868
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.0093 0.0494 0.1044
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0016 0.0011
Echinococcus granulosus thyroid hormone receptor alpha 0.0083 0.043 0.043
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0535
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.013 0.0404
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0091 0.0481 0.3512
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0096 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0096 0.0095
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0175 0.1025 0.1025
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0096 0.0096
Echinococcus multilocularis gamma secretase subunit aph 1 0.0272 0.1649 0.1649
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Schistosoma mansoni nuclear hormone receptor 0.0083 0.043 0.0429
Schistosoma mansoni alpha-glucosidase 0.0145 0.0829 0.0828
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0331 0.3726
Echinococcus multilocularis heat shock protein 0.0037 0.0135 0.0135
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0175 0.1025 0.2168
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0024 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0224 0.1341 0.144
Loa Loa (eye worm) hypothetical protein 0.0181 0.1064 0.2248
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0051 0.0227 0.0717
Echinococcus granulosus Smad4 0.0017 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0077 0.046
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0087 0.0568
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0319 0.0318
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0091 0.0481 0.0481
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0051 0.0228 0.0215
Mycobacterium leprae conserved hypothetical protein 0.0224 0.1341 0.2247
Mycobacterium tuberculosis Probable lipase LipE 0.0224 0.1341 0.144
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0016 0.0016
Treponema pallidum cation-transporting ATPase, P-type 0.0029 0.0082 0.0644
Brugia malayi hypothetical protein 0.0178 0.1045 0.3369
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.1341 1
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0091 0.0481 0.5467
Leishmania major cathepsin L-like protease 0.0135 0.077 0.5637
Echinococcus granulosus snurportin 1 0.0325 0.1991 0.1991
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Loa Loa (eye worm) hypothetical protein 0.0041 0.0163 0.0344
Echinococcus multilocularis FTZ F1 alpha 0.0175 0.1025 0.1025
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0029 0.0082 0.0055
Echinococcus multilocularis microtubule associated protein 2 0.0712 0.4479 0.4479
Leishmania major GTP-binding protein, putative 0.0022 0.0042 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0203
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0151 0.0319
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.003 0.0094 0.0199
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0083 0.043 0.087
Plasmodium vivax hypothetical protein, conserved 0.0224 0.1341 1
Echinococcus granulosus calcium transporting atpase 0.0073 0.0365 0.0365
Echinococcus granulosus endoplasmin 0.0029 0.0087 0.0087
Echinococcus multilocularis cysteine protease 0.0036 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.1341 0.9678
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Trypanosoma brucei P-type H+-ATPase, putative 0.0058 0.0269 0.1911
Loa Loa (eye worm) norepinephrine transporter 0.0181 0.1064 0.2248
Entamoeba histolytica hypothetical protein 0.002 0.0024 0.0182
Brugia malayi photoreceptor-specific nuclear receptor 0.0175 0.1025 0.3307
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0005 0.0005
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0151 0.0472
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0024 0.0023
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0925 0.5854 0.6409
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0073 0.0365 0.2641
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0075 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0051
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Loa Loa (eye worm) hypothetical protein 0.0175 0.1025 0.2168
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0016 0.0087
Brugia malayi beta-lactamase family protein 0.0224 0.1341 0.4329
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.1341 0.9678
Loa Loa (eye worm) hypothetical protein 0.0055 0.0253 0.0535
Brugia malayi Nuclear hormone receptor-like 1 0.0093 0.0494 0.1583
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.024 0.0239
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0135 0.1462
Onchocerca volvulus 0.0083 0.043 0.087
Onchocerca volvulus Protein ultraspiracle homolog 0.0175 0.1025 0.2134
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.1503 0.3176
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0096 0.0095
Onchocerca volvulus 0.0024 0.0051 0.0066
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0029 0.0082 0.0249
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0197 0.0197
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0029 0.0082 0.0085
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0096 0.0096
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0033 0.0509
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0024 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0127 0.137
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0024 0.0051
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0073 0.0365 0.0364
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0033 0.0135
Echinococcus multilocularis nuclear receptor nhr 48 0.0083 0.043 0.043
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0158 0.0493
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0221 0.132 0.2791
Trypanosoma brucei cation-transporting ATPase, putative 0.0029 0.0082 0.0499
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0114
Schistosoma mansoni jun-related protein 0.0074 0.0378 0.0377
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.1341 0.9678
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0096 0.0604
Schistosoma mansoni nuclear receptor 0.0083 0.043 0.0429
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 0.002 0.0024 0.0023
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.014 0.014
Leishmania major P-type H -ATPase, putative 0.0058 0.0269 0.1809
Leishmania major cathepsin L-like protease 0.0036 0.0127 0.0722
Schistosoma mansoni copper ABC transporter ATPase 0.0029 0.0082 0.0081
Plasmodium vivax P-type ATPase4, putative 0.0091 0.0481 0.3512
Echinococcus multilocularis geminin 0.157 1 1
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.004 0.0153 0.1042
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Echinococcus granulosus beta LACTamase domain containing family member 0.0224 0.1341 0.1341
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0051 0.0228 0.1596
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0087 0.0568
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Echinococcus multilocularis lamin 0.0027 0.0075 0.0075
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0127 0.0861
Trypanosoma cruzi heat shock protein 85, putative 0.0029 0.0087 0.0544
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0117 0.0117
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0738 0.0738
Leishmania major hypothetical protein, conserved 0.0224 0.1341 1
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.1341 1
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0029 0.0082 0.0055
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0096 0.0614
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0043 0.0178 0.0559
Trypanosoma brucei heat shock protein, putative 0.0037 0.0135 0.0898
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0051 0.0149
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0073 0.0365 0.0365
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0151 0.1028
Leishmania major heat shock protein 83-1 0.0037 0.0135 0.0783
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0058
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0127 0.2506
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0151 0.3012
Schistosoma mansoni lamin 0.0027 0.0075 0.0074
Brugia malayi Cathepsin L-like precursor 0.0036 0.0127 0.0394
Entamoeba histolytica hypothetical protein 0.002 0.0024 0.0182
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0138 0.0292
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0038 0.014 0.014
Giardia lamblia Hypothetical protein 0.0055 0.0253 0.2048
Onchocerca volvulus 0.0751 0.473 1
Schistosoma mansoni cyclin B3 0.0017 0.0008 0.0008
Plasmodium vivax calcium-transporting ATPase, putative 0.0091 0.0481 0.3512
Mycobacterium tuberculosis Probable hydrolase 0.0224 0.1341 0.144
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0137 0.0782 0.0782
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0175 0.1025 0.1025
Echinococcus granulosus heat shock protein 0.0037 0.0135 0.0135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0513 0.0512
Echinococcus granulosus cysteine protease 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0158 0.0158
Entamoeba histolytica hypothetical protein 0.0152 0.0873 1
Loa Loa (eye worm) Smad1 0.0017 0.0007 0.0016
Leishmania major cathepsin L-like protease 0.0036 0.0127 0.0722
Brugia malayi Serotonin receptor 0.047 0.2924 0.946
Entamoeba histolytica cysteine protease, putative 0.0018 0.0016 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0127 0.0861
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0073 0.0365 0.0364
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0319 0.0674
Brugia malayi hypothetical protein 0.0083 0.043 0.1376
Echinococcus granulosus zinc finger protein 0.002 0.0026 0.0026
Mycobacterium ulcerans lipase LipD 0.0224 0.1341 0.2247
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0158 0.1068
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0175 0.1025 0.3307
Echinococcus multilocularis beta LACTamase domain containing family member 0.0224 0.1341 0.1341
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0134 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.077 0.5691
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.0909
Onchocerca volvulus Bile acid receptor homolog 0.0175 0.1025 0.2134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0096 0.0203
Echinococcus multilocularis phosphoserine phosphatase 0.0018 0.0015 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0738 0.0776

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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