Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0193 | 0.0411 | 0.5 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0193 | 0.0411 | 0.0411 |
Brugia malayi | Peptidase family M1 containing protein | 0.0193 | 0.0411 | 0.0908 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0193 | 0.0411 | 0.0411 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0193 | 0.0411 | 0.0411 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0157 | 0.031 | 0.031 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.3634 | 1 | 1 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Onchocerca volvulus | 0.0193 | 0.0411 | 0.5 | |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0193 | 0.0411 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0193 | 0.0411 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0171 | 0.035 | 0.035 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0253 | 0.0253 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0193 | 0.0411 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0193 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0193 | 0.0411 | 0.0411 |
Brugia malayi | hypothetical protein | 0.1671 | 0.4529 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0193 | 0.0411 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0193 | 0.0411 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0193 | 0.0411 | 1 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0193 | 0.0411 | 0.0411 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0193 | 0.0411 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0157 | 0.031 | 0.031 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0193 | 0.0411 | 0.0908 |
Echinococcus granulosus | aminopeptidase N | 0.0193 | 0.0411 | 0.0411 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0193 | 0.0411 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0193 | 0.0411 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0193 | 0.0411 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0193 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.0411 | 0.0411 |
Brugia malayi | Peptidase family M1 containing protein | 0.0193 | 0.0411 | 0.0908 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0193 | 0.0411 | 0.0411 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0157 | 0.031 | 0.031 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0157 | 0.031 | 0.0685 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0193 | 0.0411 | 0.5 |
Brugia malayi | TATA binding protein associated factor | 0.0193 | 0.0411 | 0.0908 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0193 | 0.0411 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0193 | 0.0411 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.0411 | 0.0411 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0193 | 0.0411 | 0.5 |
Onchocerca volvulus | 0.0193 | 0.0411 | 0.5 | |
Trypanosoma brucei | aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0193 | 0.0411 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0193 | 0.0411 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0193 | 0.0411 | 0.5 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0193 | 0.0411 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0193 | 0.0411 | 0.5 |
Brugia malayi | hypothetical protein | 0.0193 | 0.0411 | 0.0908 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0193 | 0.0411 | 0.5 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0193 | 0.0411 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.3634 | 1 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0171 | 0.035 | 0.035 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.3634 | 1 | 1 |
Echinococcus multilocularis | aminopeptidase N | 0.0193 | 0.0411 | 0.0411 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0193 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.0411 | 0.0411 |
Brugia malayi | hypothetical protein | 0.0193 | 0.0411 | 0.0908 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0193 | 0.0411 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0193 | 0.0411 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.