Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0743 | 0.2246 | 0.0488 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1898 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0712 | 0.2035 | 0.3199 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0743 | 0.2246 | 0.1649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Leishmania major | cathepsin L-like protease | 0.0743 | 0.2246 | 0.0488 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0743 | 0.2246 | 0.2246 |
Loa Loa (eye worm) | hypothetical protein | 0.0743 | 0.2246 | 0.1649 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0515 | 0.0715 | 0.0715 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0743 | 0.2246 | 0.2246 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0743 | 0.2246 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Plasmodium vivax | vivapain-2 | 0.0743 | 0.2246 | 1 |
Leishmania major | cathepsin L-like protease | 0.0743 | 0.2246 | 0.0488 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0743 | 0.2246 | 0.2246 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0743 | 0.2246 | 0.2246 |
Echinococcus multilocularis | cathepsin b | 0.1898 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0743 | 0.2246 | 0.2246 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1898 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0743 | 0.2246 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Leishmania major | cathepsin L-like protease | 0.0743 | 0.2246 | 0.0488 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0743 | 0.2246 | 0.2246 |
Giardia lamblia | Cathepsin B precursor | 0.0712 | 0.2035 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0712 | 0.2035 | 0.9061 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0743 | 0.2246 | 1 |
Leishmania major | cathepsin L-like protease | 0.1356 | 0.6362 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0515 | 0.0715 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.1356 | 0.6362 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Plasmodium vivax | vivapain-2 | 0.0743 | 0.2246 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0743 | 0.2246 | 0.2246 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0743 | 0.2246 | 0.0488 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0743 | 0.2246 | 0.2246 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0743 | 0.2246 | 0.2246 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Echinococcus granulosus | cathepsin b | 0.1898 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Leishmania major | cathepsin L-like protease | 0.1356 | 0.6362 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0515 | 0.0715 | 0.0715 |
Echinococcus granulosus | cathepsin b | 0.1898 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1128 | 0.483 | 0.483 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1898 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Loa Loa (eye worm) | cathepsin B | 0.0712 | 0.2035 | 0.1422 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0743 | 0.2246 | 0.2246 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0743 | 0.2246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1898 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1356 | 0.6362 | 0.6362 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0515 | 0.0715 | 0.3182 |
Brugia malayi | cathepsin L-like precursor | 0.0515 | 0.0715 | 0.0715 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1356 | 0.6362 | 0.6362 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Leishmania major | cysteine peptidase A (CPA) | 0.0743 | 0.2246 | 0.0488 |
Toxoplasma gondii | cathepsin CPL | 0.0743 | 0.2246 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0515 | 0.0715 | 0.0715 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0743 | 0.2246 | 0.1649 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0743 | 0.2246 | 0.2246 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0743 | 0.2246 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Echinococcus granulosus | cathepsin l1 | 0.0743 | 0.2246 | 0.2246 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0712 | 0.2035 | 0.2035 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0712 | 0.2035 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Onchocerca volvulus | 0.0743 | 0.2246 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1356 | 0.6362 | 0.6362 |
Brugia malayi | Cathepsin L-like precursor | 0.0515 | 0.0715 | 0.0715 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0743 | 0.2246 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0743 | 0.2246 | 0.1649 |
Echinococcus multilocularis | cathepsin b | 0.1898 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0743 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0712 | 0.2035 | 0.2035 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0712 | 0.2035 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0743 | 0.2246 | 0.1649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0743 | 0.2246 | 0.2246 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1356 | 0.6362 | 0.6362 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0515 | 0.0715 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0515 | 0.0715 | 0.0715 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0793 | 0.2584 | 0.2584 |
Onchocerca volvulus | Cathepsin F homolog | 0.0743 | 0.2246 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0743 | 0.2246 | 0.1649 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1356 | 0.6362 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0743 | 0.2246 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0743 | 0.2246 | 0.2246 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1898 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1898 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.