Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0159 | 0.2935 | 0.3202 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.4259 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0126 | 0.0749 | 0.1758 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0252 | 0.9166 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.3821 | 0.4169 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0252 | 0.9166 | 0.9166 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0152 | 0.2518 | 0.5912 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0126 | 0.0749 | 0.1758 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.9066 | 0.9891 |
Echinococcus granulosus | geminin | 0.0179 | 0.4259 | 1 |
Brugia malayi | hypothetical protein | 0.0172 | 0.3821 | 0.3821 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0252 | 0.9166 | 0.9166 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.2518 | 0.5912 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.4259 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0115 | 0 | 0.5 |
Brugia malayi | hypoxia-induced factor 1 | 0.0159 | 0.2935 | 0.2935 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0115 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0115 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.0749 | 0.1758 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.2518 | 0.5912 |
Echinococcus multilocularis | geminin | 0.0179 | 0.4259 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.