Detailed information for compound 833591

Basic information

Technical information
  • TDR Targets ID: 833591
  • Name: 3-methyl-N-[2-[1-(2-methylbutyl)benzimidazol- 2-yl]ethyl]benzamide
  • MW: 349.469 | Formula: C22H27N3O
  • H donors: 1 H acceptors: 2 LogP: 4.69 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(Cn1c(CCNC(=O)c2cccc(c2)C)nc2c1cccc2)C
  • InChi: 1S/C22H27N3O/c1-4-16(2)15-25-20-11-6-5-10-19(20)24-21(25)12-13-23-22(26)18-9-7-8-17(3)14-18/h5-11,14,16H,4,12-13,15H2,1-3H3,(H,23,26)
  • InChiKey: JYRGRKKHQUKLFA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-methyl-N-[2-[1-(2-methylbutyl)-2-benzimidazolyl]ethyl]benzamide
  • T5443139

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0054 0.0254 0.0425
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0803 0.1405
Onchocerca volvulus 0.0014 0.0017 0.0012
Schistosoma mansoni opsin-like receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0113 0.0113
Treponema pallidum glutamate/aspartate transporter 0.0339 0.1962 1
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0044 0.0196 0.0342
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0497
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis expressed conserved protein 0.0097 0.0508 0.0508
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0012 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0619 0.2891
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0113 0.0198
Brugia malayi MH2 domain containing protein 0.0144 0.0793 0.1737
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.3992
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0196 0.0409
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0113 0.0605 0.7495
Loa Loa (eye worm) fibroinase 0.002 0.0051 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0605 0.2072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0113 0.0113
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0134 0.0234
Leishmania major cathepsin L-like protease 0.0077 0.0392 0.4797
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0605 0.1058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0134 0.0234
Echinococcus granulosus importin subunit beta 1 0.0091 0.0472 0.0826
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Brugia malayi jmjC domain containing protein 0.0016 0.0027 0.0035
Echinococcus granulosus 7tm_1 domain containing protein 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0113 0.0226
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0803 0.9901
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi nuclear hormone receptor 0.0014 0.0017 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Brugia malayi hypothetical protein 0.0244 0.1389 0.3059
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0803 0.144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0364 0.2111 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0034 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0113 0.0605 0.1041
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0555 0.0971
Loa Loa (eye worm) hypothetical protein 0.0044 0.0196 0.0323
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 0.0232
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Trichomonas vaginalis set domain proteins, putative 0.0492 0.2877 1
Onchocerca volvulus 0.0034 0.0134 0.0272
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0113 0.0113
Trichomonas vaginalis importin beta-1, putative 0.0073 0.037 0.1252
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0196 0.3992
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0035 0.014 0.0245
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0339 0.1962 0.3434
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0165 0.0917 0.1588
Echinococcus granulosus hypothetical protein 0.0034 0.0134 0.0234
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0034 0.0134 0.0215
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0086 0.0351
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0113 0.0198
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0017 0.0029
Echinococcus multilocularis orexin receptor type 2 0.0034 0.0134 0.0134
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Brugia malayi putative neuropeptide receptor NPR1 0.0034 0.0134 0.0272
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.032 0.1846 0.3229
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0134 0.0234
Echinococcus multilocularis dro:myosuppressin receptor 0.0034 0.0134 0.0134
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0162 0.1875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Echinococcus granulosus microtubule associated protein 2 0.07 0.4121 0.7211
Schistosoma mansoni hypothetical protein 0.0035 0.014 0.0245
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0113 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Echinococcus multilocularis protein patched 0.0044 0.0194 0.0194
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0497
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0051 0.0854
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0228 0.0481
Brugia malayi Serotonin receptor 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.007
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Brugia malayi conserved hypotetical protein 0.0014 0.0017 0.0012
Trichomonas vaginalis ran, putative 0.0046 0.0203 0.0669
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.014 0.014
Echinococcus granulosus orexin receptor type 2 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0803 0.144
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0113 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Echinococcus granulosus sex peptide receptor 0.0034 0.0134 0.0234
Trichomonas vaginalis hypothetical protein 0.0017 0.0033 0.0076
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0134 0.0134
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0113 0.0198
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0017 0.0012
Plasmodium vivax glutathione reductase, putative 0.0039 0.0166 0.195
Loa Loa (eye worm) hypothetical protein 0.0076 0.0384 0.0653
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0287 0.0502
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Mycobacterium tuberculosis Conserved protein 0.0146 0.0803 0.144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Brugia malayi nuclear hormone receptor 0.0031 0.0113 0.0226
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) hypothetical protein 0.0063 0.0308 0.0521
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) PDE1B protein 0.0044 0.0196 0.0323
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0113 0.0178
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0308 0.054
Schistosoma mansoni amine GPCR 0.0034 0.0134 0.0234
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0034 0.0134 0.0134
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0089
Brugia malayi sulfakinin receptor protein 0.0034 0.0134 0.0272
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0339 0.1962 0.1962
Plasmodium falciparum glutathione reductase 0.0039 0.0166 0.3352
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0027 0.0071
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0044 0.0196 0.2322
Echinococcus granulosus g protein coupled receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.0546 0.0546
Brugia malayi Thioredoxin reductase 0.0039 0.0166 0.0344
Onchocerca volvulus Cathepsin F homolog 0.002 0.0051 0.0089
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0027 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0044 0.0196 0.0342
Leishmania major cathepsin L-like protease 0.0077 0.0392 0.4797
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0044 0.0196 0.2322
Echinococcus multilocularis allatostatin A receptor 0.0034 0.0134 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0027 0.0034
Schistosoma mansoni opsin-like receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0134 0.0234
Echinococcus granulosus tachykinin peptides receptor 99D 0.0034 0.0134 0.0234
Echinococcus multilocularis neuropeptide s receptor 0.0508 0.2971 0.2971
Echinococcus multilocularis tumor protein p63 0.0329 0.1903 0.1903
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.1733 0.8199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.0766 0.4515 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0339 0.1962 0.3434
Schistosoma mansoni survival motor neuron protein 0.005 0.0228 0.0399
Brugia malayi hypothetical protein 0.0016 0.0027 0.0034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0034 0.0134 0.0134
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0766 0.4515 0.79
Toxoplasma gondii HEAT repeat-containing protein 0.0091 0.0472 0.2192
Brugia malayi steroid hormone receptor 0.0031 0.0113 0.0226
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0027 0.0027
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0203 0.0203
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0027
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0803 0.144
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0162 0.0273
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0028
Plasmodium falciparum importin beta, putative 0.0091 0.0472 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0162 0.1893
Echinococcus granulosus geminin 0.0337 0.1948 0.3409
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Brugia malayi hypothetical protein 0.0016 0.0027 0.0034
Brugia malayi ecdysteroid receptor 0.0031 0.0113 0.0226
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0392 0.4797
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0313 0.0548
Echinococcus multilocularis neutral amino acid transporter A 0.0766 0.4515 0.4515
Loa Loa (eye worm) melatonin receptor type 1A 0.0034 0.0134 0.0215
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0162 0.0333
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0043 0.0185 0.0323
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0113 0.0198
Echinococcus granulosus expressed conserved protein 0.0097 0.0508 0.0889
Echinococcus granulosus excitatory amino acid transporter 3 0.0766 0.4515 0.79
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0034 0.0134 0.0134
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0086 0.1602
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.01 0.0529 0.094
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Plasmodium falciparum phosphodiesterase gamma, putative 0.0044 0.0196 0.3992
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Schistosoma mansoni myosin xvIII 0.0034 0.0134 0.0234
Brugia malayi ORL1-like opioid receptor 0.0034 0.0134 0.0272
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.1733 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0134 0.0234
Brugia malayi kap beta 3 protein 0.0017 0.0033 0.0048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trypanosoma brucei trypanothione reductase 0.0039 0.0166 0.195
Brugia malayi jmjC domain containing protein 0.0064 0.0313 0.0671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Echinococcus multilocularis dnaJ subfamily B 0.0848 0.5005 0.5005
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.2322
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0054 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0034 0.0134 0.0134
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus granulosus neutral amino acid transporter A 0.0766 0.4515 0.79
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0803 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0196 0.0645
Schistosoma mansoni hypothetical protein 0.0034 0.0134 0.0234
Onchocerca volvulus 0.0034 0.0134 0.0272
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0035 0.014 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Onchocerca volvulus 0.0034 0.0134 0.0272
Echinococcus granulosus neuropeptide receptor A26 0.0508 0.2971 0.5199
Leishmania major hypothetical protein, conserved 0.0044 0.0196 0.2322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.1389 0.243
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0113 0.0198
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0293 0.0293
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0044 0.0196 0.0409
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0931 0.5506 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0162 0.3255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0134 0.0134
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0308 0.0308
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0034 0.0134 0.0215
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.014 0.0286
Echinococcus multilocularis excitatory amino acid transporter 2 0.0766 0.4515 0.4515
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0364 0.2111 0.2111
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0339 0.1962 0.1962
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0196 0.0409
Brugia malayi nuclear receptor NHR-88 0.0031 0.0113 0.0226
Echinococcus granulosus g protein coupled receptor 0.0034 0.0134 0.0234
Brugia malayi tailless protein 0.0014 0.0017 0.0012
Schistosoma mansoni amine GPCR 0.0034 0.0134 0.0234
Echinococcus granulosus Excitatory amino acid transporter 0.0766 0.4515 0.79
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus multilocularis muscleblind protein 0.0165 0.0917 0.0917
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0162 0.0334
Brugia malayi glutathione reductase 0.0039 0.0166 0.0344
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0033 0.0262
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0766 0.4515 0.8196
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0034 0.0134 0.0272
Schistosoma mansoni biogenic amine receptor 0.0034 0.0134 0.0234
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0113 0.0198
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0111 0.0593 0.1021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.0546 0.3103
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0308 0.054
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0027 0.0189
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0033 0.0038
Loa Loa (eye worm) hypothetical protein 0.0111 0.0593 0.1021
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.01 0.0529 0.1755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0134 0.0134
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0162 0.1893
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0086 0.0932
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0044 0.0196 0.2322
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0364 0.2111 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0162 0.0264
Loa Loa (eye worm) hypothetical protein 0.0244 0.1389 0.2415
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0134 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0011 0.0001
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0017 0.0012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis importin subunit beta 1 0.0091 0.0472 0.0472
Schistosoma mansoni hypothetical protein 0.0337 0.1948 0.3409
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.2322
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0034 0.0134 0.0272
Echinococcus multilocularis GPCR, family 2 0.0035 0.014 0.014
Schistosoma mansoni hypothetical protein 0.0034 0.0134 0.0234
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0047 0.0083
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0803 0.144
Onchocerca volvulus 0.0063 0.0308 0.066
Toxoplasma gondii thioredoxin reductase 0.0039 0.0166 0.0735
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0017 0.0029
Schistosoma mansoni cpg binding protein 0.0063 0.0307 0.0537
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0086 0.1602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0033 0.0099
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0113 0.0226
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0044 0.0196 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0113 0.0178
Plasmodium vivax transportin, putative 0.0017 0.0033 0.0262
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0051 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0803 0.2764
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0134 0.0234
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0313 0.0548
Echinococcus multilocularis cpg binding protein 0.0063 0.0307 0.0307
Onchocerca volvulus 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Brugia malayi G-protein coupled receptor 0.0034 0.0134 0.0272
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0089
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0203 0.2412
Onchocerca volvulus 0.0034 0.0134 0.0272
Leishmania major hypothetical protein, conserved 0.0026 0.0086 0.0932
Schistosoma mansoni hypothetical protein 0.0076 0.0384 0.0671
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0203 0.0909
Onchocerca volvulus 0.0034 0.0134 0.0272
Echinococcus granulosus g-protein coupled receptor 0.0034 0.0134 0.0234
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0027
Plasmodium falciparum transportin 0.0017 0.0033 0.045
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.009 0.0469 0.0831
Plasmodium vivax vivapain-2 0.002 0.0051 0.0497
Echinococcus granulosus importin 5 0.0017 0.0033 0.0057
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0293 0.0293
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0196 0.2322
Schistosoma mansoni amine GPCR 0.0034 0.0134 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Mycobacterium leprae Probable lipase LipE 0.0146 0.0803 0.977
Leishmania major cysteine peptidase A (CPA) 0.002 0.0051 0.0497
Brugia malayi RNA, U transporter 1 0.0257 0.1471 0.3242
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0673 0.0673
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Mycobacterium ulcerans hypothetical protein 0.0146 0.0803 0.9901
Brugia malayi jmjC domain containing protein 0.0016 0.0027 0.0035
Echinococcus multilocularis importin 5 0.0017 0.0033 0.0033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Schistosoma mansoni opsin-like receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.032 0.1846 0.3216
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0134 0.0234
Onchocerca volvulus 0.0492 0.2877 0.6363
Brugia malayi Latrophilin receptor protein 2 0.0035 0.014 0.0286
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0803 0.2764
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0113 0.0113
Echinococcus multilocularis serotonin receptor 0.0034 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0811 0.1454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Echinococcus granulosus muscleblind protein 0.0165 0.0917 0.1604
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0053 0.0092
Brugia malayi Pre-SET motif family protein 0.0433 0.252 0.5571
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0308 0.1412
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0017 0.0012
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0027 0.0027
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0012 0.0002
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0673 0.3149
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0113 0.0178
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0162 0.0874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0113 0.0198
Echinococcus multilocularis neuropeptide FF receptor 2 0.0034 0.0134 0.0134
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0203 0.0355
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0134 0.0134
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0673 0.8274
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0803 1
Brugia malayi jmjC domain containing protein 0.0016 0.0027 0.0035
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0017 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0605 0.2072
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Onchocerca volvulus 0.0034 0.0134 0.0272
Onchocerca volvulus 0.0034 0.0134 0.0272
Brugia malayi jmjC domain containing protein 0.0061 0.0293 0.0626
Brugia malayi Excitatory amino acid transporter 0.0766 0.4515 1
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Onchocerca volvulus 0.0014 0.0017 0.0012
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.032 0.1846 0.1846
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0194 0.0194
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0219 0.0383
Schistosoma mansoni microtubule-associated protein tau 0.07 0.4121 0.7211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni ran 0.0046 0.0203 0.0355
Brugia malayi Dopamine receptor protein 2 0.0034 0.0134 0.0272
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0044 0.0196 0.0323
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0051 0.0497
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0012 0.0021
Schistosoma mansoni zinc finger protein 0.0014 0.0017 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Brugia malayi larval opioid receptor 0.0034 0.0134 0.0272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0605 0.7495
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0051 0.0854
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0027
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.032 0.1846 0.4073
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0673 0.1178
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0017 0.0009
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus multilocularis G protein coupled receptor 139 0.0034 0.0134 0.0134
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0134 0.0134
Onchocerca volvulus 0.0034 0.0134 0.0272
Echinococcus multilocularis translational activator gcn1 0.0017 0.0033 0.0033
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0803 0.1758
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0113 0.0198
Loa Loa (eye worm) beta-lactamase 0.0146 0.0803 0.1388
Brugia malayi N-terminal motif family protein 0.0203 0.1148 0.2525
Brugia malayi GnHR receptor homolog 0.0034 0.0134 0.0272
Schistosoma mansoni alpha-1 adrenergic receptor 0.0034 0.0134 0.0234
Leishmania major cathepsin L-like protease 0.0077 0.0392 0.4797
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0293 0.0513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Schistosoma mansoni ap endonuclease 0.0039 0.0162 0.0283
Echinococcus granulosus neutral amino acid transporter A 0.0766 0.4515 0.79
Loa Loa (eye worm) hypothetical protein 0.0044 0.0194 0.0321
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0811 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.081 0.081
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0803 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0113 0.0113
Echinococcus granulosus GPCR family 2 0.0035 0.014 0.0245
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0673 0.8274
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0051
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0051 0.0854
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0012 0.0004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0113 0.0605 0.3448
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0086 0.0932
Schistosoma mansoni neuropeptide receptor 0.0034 0.0134 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0012 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0113 0.0226
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0196 0.0342
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.2322
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0033 0.0099
Brugia malayi Importin beta-1 subunit 0.0091 0.0472 0.1023
Echinococcus granulosus dro:myosuppressin receptor 0.0034 0.0134 0.0234
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 0.0232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus granulosus Excitatory amino acid transporter 0.0766 0.4515 0.79
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0113 0.0198
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0051
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0203 0.2412
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0027 0.0189
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0113 0.0226
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0134 0.0234
Echinococcus granulosus snurportin 1 0.0966 0.5715 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus tumor protein p63 0.0329 0.1903 0.3329
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0203 0.1148 0.1994
Schistosoma mansoni growth hormone secretagogue receptor 0.0034 0.0134 0.0234
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0032 0.0032
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0392 0.4797
Brugia malayi CHE-14 protein 0.0044 0.0194 0.0406
Brugia malayi G protein-coupled receptor F59B2.13 0.0034 0.0134 0.0272
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi jmjC domain containing protein 0.0016 0.0027 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0027 0.0071
Treponema pallidum glutamate transporter 0.0339 0.1962 1
Echinococcus multilocularis Excitatory amino acid transporter 0.0766 0.4515 0.4515
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.037 0.1252
Trypanosoma brucei importin beta-1 subunit, putative 0.0091 0.0472 0.5817
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.01 0.0529 0.094
Onchocerca volvulus 0.006 0.0287 0.0611
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0605 0.1058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.1042 0.1806
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0027 0.0047
Leishmania major hypothetical protein, conserved 0.0016 0.0027 0.0189
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0134 0.0134
Onchocerca volvulus 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0044 0.0196 0.0323
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0044 0.0196 0.0196
Echinococcus granulosus transportin 1 0.0017 0.0033 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0113 0.0226
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0027 0.0047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0017 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0803 0.2764
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.1733 1
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0113 0.0198
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0196 0.2322
Schistosoma mansoni hypothetical protein 0.0337 0.1948 0.3409
Onchocerca volvulus 0.002 0.0051 0.0089
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0017 0.0009
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0027 0.0027
Echinococcus multilocularis excitatory amino acid transporter 2 0.0766 0.4515 0.4515
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Mycobacterium tuberculosis Conserved protein 0.0146 0.0803 0.144
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0113 0.0226
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0166 0.0281
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi Calcitonin receptor-like protein seb-1 0.0111 0.0593 0.1293
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0113 0.0198
Schistosoma mansoni neuropeptide receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0766 0.4515 0.4515
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0017 0.0029
Brugia malayi beta-lactamase 0.0146 0.0803 0.1758
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0803 0.144
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0803 0.144
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.037 0.4521
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0134 0.0215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Schistosoma mansoni amine GPCR 0.0034 0.0134 0.0234
Brugia malayi nuclear receptor RXR 0.0014 0.0017 0.0012
Toxoplasma gondii ABC1 family protein 0.0146 0.0803 0.3768
Giardia lamblia hypothetical protein 0.0044 0.0196 0.0875
Schistosoma mansoni hypothetical protein 0.0035 0.014 0.0245
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0134 0.0134
Entamoeba histolytica cysteine protease, putative 0.002 0.0051 0.0232
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0086 0.0932
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0027 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0027 0.0028
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0113 0.0605 0.2824
Brugia malayi G-protein coupled receptor 0.0034 0.0134 0.0272
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0194 0.034
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0027 0.0325
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0113 0.0178
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0017 0.0017
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Brugia malayi Serotonin receptor 0.0034 0.0134 0.0272
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Entamoeba histolytica hypothetical protein 0.0073 0.037 0.2082
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0028
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.014 0.014
Echinococcus multilocularis Excitatory amino acid transporter 0.0766 0.4515 0.4515
Chlamydia trachomatis neutral amino acid transporter 0.0339 0.1962 0.4331
Brugia malayi AKH receptor 0.0034 0.0134 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Brugia malayi Muscleblind-like protein 0.0165 0.0917 0.2011
Echinococcus multilocularis serotonin receptor 0.0034 0.0134 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Leishmania major cAMP-specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0113 0.0226
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0766 0.4515 1
Echinococcus granulosus neutral amino acid transporter 0.0766 0.4515 0.79
Brugia malayi nuclear receptor NHR-67 0.0014 0.0017 0.0012
Plasmodium vivax vivapain-2 0.002 0.0051 0.0497
Schistosoma mansoni cpg binding protein 0.0063 0.0307 0.0537
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0034 0.0134 0.0134
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0803 0.1405
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0364 0.2111 0.3694
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0017 0.0029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0203 0.2412
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0134 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0196 0.0645
Leishmania major hypothetical protein, conserved 0.0044 0.0196 0.2322
Leishmania major GTP-binding protein, putative 0.0046 0.0203 0.2412
Echinococcus granulosus fmrfamide receptor 0.0034 0.0134 0.0234
Echinococcus granulosus allatostatin A receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0605 0.0605
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0027 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0673 0.1178
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.0203 0.2412
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0113 0.0198
Loa Loa (eye worm) DR-78 0.0014 0.0017 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0113 0.0605 0.1058
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0162 0.0283
Mycobacterium tuberculosis Putative ferredoxin reductase 0.009 0.0469 0.0831
Onchocerca volvulus 0.0034 0.0134 0.0272
Echinococcus granulosus neuropeptide s receptor 0.0508 0.2971 0.5199
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0113 0.0605 0.1058
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Brugia malayi ecdysone receptor 0.0014 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.0043 0.0185 0.0323
Brugia malayi Pre-SET motif family protein 0.0063 0.0308 0.066
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0044 0.0196 0.0409
Brugia malayi RE15519p 0.0034 0.0134 0.0272
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0034 0.0134 0.0234
Schistosoma mansoni patched 1 0.0044 0.0194 0.034
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0044 0.0196 0.0196
Schistosoma mansoni neuropeptide receptor 0.0034 0.0134 0.0234
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0017 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0141
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0113 0.0198
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0166 0.195
Plasmodium vivax importin-beta 2, putative 0.0091 0.0472 0.5817
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0194 0.0321
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0605 0.7495
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Brugia malayi nuclear receptor NHR-88 0.0014 0.0017 0.0012
Echinococcus granulosus translational activator gcn1 0.0017 0.0033 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0113 0.0198
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0113 0.0226
Onchocerca volvulus 0.0034 0.0134 0.0272
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0027 0.0047
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0044 0.0196 0.0409
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0027 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0027 0.0028
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0497
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0803 0.2764
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0034 0.0134 0.0215
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Onchocerca volvulus 0.002 0.0051 0.0089
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0293 0.0513
Echinococcus granulosus peptide allatostatin:somatostatin 0.0034 0.0134 0.0234
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0027 0.0028
Onchocerca volvulus 0.002 0.0051 0.0089
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.009 0.0469 0.0831
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.014 0.0245
Loa Loa (eye worm) hypothetical protein 0.0048 0.0219 0.0364
Schistosoma mansoni importin beta-1 0.0091 0.0472 0.0826
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0364 0.2111 0.3694
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0194 0.064
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0134 0.0234
Brugia malayi latrophilin 2 splice variant baaae 0.0076 0.0384 0.0827
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0034 0.0134 0.0234
Schistosoma mansoni hypothetical protein 0.0966 0.5715 1
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0169 0.0296
Echinococcus granulosus ubiquitin specific protease 41 0.0113 0.0605 0.1058
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0017 0.0029
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0027 0.0189
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0113 0.0198
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0196 0.0196
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0113 0.0605 0.1318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0162 0.0713
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0113 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0033 0.0125
Schistosoma mansoni cpg binding protein 0.006 0.0287 0.0501
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Mycobacterium tuberculosis Probable dehydrogenase 0.009 0.0469 0.0831
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Onchocerca volvulus 0.0034 0.0134 0.0272
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0162 0.0526
Leishmania major hypothetical protein, conserved 0.0146 0.0803 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0034 0.0134 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0113 0.0226
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0034 0.0134 0.0234
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0293 0.3549
Echinococcus granulosus excitatory amino acid transporter 2 0.0766 0.4515 0.79
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0605 0.7495
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0194 0.034
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0113 0.0198
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0134 0.0234
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0017 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0134 0.0134
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0196 0.0196
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0134 0.0134
Schistosoma mansoni adenoreceptor 0.0034 0.0134 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1042 0.1822
Brugia malayi Dopamine receptor 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0103 0.0546 0.0937
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0134 0.0234
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0044 0.0196 0.0342
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0113 0.0198
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0026 0.0086 0.013
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0166 0.0272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1042 0.1822
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0017 0.0029
Brugia malayi hypothetical protein 0.0014 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Echinococcus granulosus cpg binding protein 0.0063 0.0307 0.0537
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.1733 0.8824
Onchocerca volvulus 0.0034 0.0134 0.0272
Loa Loa (eye worm) excitatory amino acid transporter 0.0766 0.4515 0.7896
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0162 0.0526
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0086 0.0932
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.014 0.0226
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0673 0.1178
Echinococcus granulosus 7TM GPCR rhodopsin 0.0034 0.0134 0.0234
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0287 0.0483
Schistosoma mansoni biogenic amine receptor 0.0034 0.0134 0.0234
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0196 0.3992
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0196 0.0409
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0134 0.0234
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Brugia malayi Tachykinin-like peptides receptor 99D 0.0034 0.0134 0.0272
Plasmodium vivax phosphodiesterase gamma, putative 0.0044 0.0196 0.2322
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0605 0.0605
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0017 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0017 0.0029
Leishmania major trypanothione reductase 0.0039 0.0166 0.195
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0027 0.0047
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0673 0.8356
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0917 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Brugia malayi neuropeptide F receptor 0.0034 0.0134 0.0272
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0169 0.0169
Schistosoma mansoni hypothetical protein 0.0043 0.0185 0.0323
Schistosoma mansoni hypothetical protein 0.0043 0.0185 0.0323
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0162 0.0768
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0134 0.0215
Leishmania major hypothetical protein, conserved 0.0017 0.0033 0.0262
Chlamydia trachomatis glutamate symporter 0.0766 0.4515 1
Echinococcus granulosus excitatory amino acid transporter 2 0.0766 0.4515 0.79
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus granulosus g protein coupled receptor 0.0034 0.0134 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Mycobacterium ulcerans beta-lactamase 0.0146 0.0803 0.9901
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0766 0.4515 0.4515
Onchocerca volvulus 0.0146 0.0803 0.1758
Schistosoma mansoni ap endonuclease 0.0039 0.0162 0.0283
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0196 0.2322
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0032 0.0057
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0017 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0196 0.0342
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0673 0.8274
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0113 0.0226
Brugia malayi nuclear receptor RXR 0.0016 0.0027 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0113 0.0198
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0034 0.0134 0.0134
Echinococcus granulosus somatostatin receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis sex peptide receptor 0.0034 0.0134 0.0134
Echinococcus multilocularis g-protein coupled receptor 0.0034 0.0134 0.0134
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0134 0.0234
Echinococcus granulosus dnaJ subfamily B 0.0848 0.5005 0.8757
Schistosoma mansoni hypothetical protein 0.0034 0.0134 0.0234
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0113 0.0198
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0033 0.0038
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0134 0.0134
Brugia malayi Dopamine receptor protein 1 0.0034 0.0134 0.0272
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0803 1
Onchocerca volvulus 0.0146 0.0803 0.1758
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0051 0.009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0034 0.0134 0.0272
Echinococcus granulosus neuropeptide receptor 0.0034 0.0134 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0113 0.0226
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0134 0.0215
Schistosoma mansoni histamine h1 receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis excitatory amino acid transporter 3 0.0766 0.4515 0.4515
Leishmania major importin beta-1 subunit, putative 0.0073 0.037 0.4521
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0028
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus granulosus sodium:dicarboxylate symporter 0.0766 0.4515 0.79
Echinococcus multilocularis geminin 0.0337 0.1948 0.1948
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0111 0.0593 0.1293
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.014 0.0245
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0032 0.0057
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0034 0.0134 0.0234
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0433 0.252 0.4398
Schistosoma mansoni neuropeptide receptor 0.0034 0.0134 0.0234
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0803 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Echinococcus multilocularis protein dispatched 1 0.005 0.0232 0.0232
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0017 0.0017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0113 0.0113
Brugia malayi neuropeptide F receptor 0.0034 0.0134 0.0272
Echinococcus multilocularis neuropeptide receptor A26 0.0508 0.2971 0.2971
Loa Loa (eye worm) hypothetical protein 0.0044 0.0196 0.0323
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Onchocerca volvulus Neuropeptide F receptor homolog 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0165 0.0917 0.1588
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0027 0.0047
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0134 0.0134
Echinococcus granulosus neuropeptide receptor 0.0034 0.0134 0.0234
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0308 0.0308
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0134 0.0234
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0113 0.0113
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.1042 0.1822
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0392 0.4797
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Plasmodium falciparum thioredoxin reductase 0.0039 0.0166 0.3352
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Trichomonas vaginalis esterase, putative 0.0146 0.0803 0.2764
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.3992
Onchocerca volvulus 0.0048 0.0219 0.0461
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi beta-lactamase family protein 0.0146 0.0803 0.1758
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi putative neuropeptide receptor 0.0034 0.0134 0.0272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0308 0.054
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0162 0.1893
Schistosoma mansoni hypothetical protein 0.0035 0.014 0.0245
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0134 0.0134
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0196 0.0645
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.1148 0.2525
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.1042 0.1042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1042 0.1822
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0051 0.0089
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0017 0.0029
Echinococcus granulosus cathepsin l1 0.0014 0.0011 0.002
Schistosoma mansoni hypothetical protein 0.0034 0.0134 0.0234
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.0546 0.0955
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0034 0.0134 0.0215
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0113 0.0226
Echinococcus granulosus serotonin receptor 0.0034 0.0134 0.0234
Giardia lamblia Hypothetical protein 0.0044 0.0196 0.0875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Echinococcus multilocularis snurportin 1 0.0966 0.5715 0.5715
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0364 0.2111 0.2111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0673 0.1203
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0966 0.5715 1
Mycobacterium ulcerans lipase LipD 0.0146 0.0803 0.9901
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0044 0.0196 0.0196
Mycobacterium tuberculosis Probable reductase 0.009 0.0469 0.0831
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0011 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0313 0.053
Echinococcus multilocularis G-protein coupled receptor, putative 0.0034 0.0134 0.0134
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0162 0.1893
Plasmodium vivax SET domain protein, putative 0.0063 0.0308 0.3747
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0034 0.0134 0.0134
Schistosoma mansoni nuclear receptor 0.0014 0.0017 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.0546 0.1186
Schistosoma mansoni biogenic amine receptor 0.0034 0.0134 0.0234
Onchocerca volvulus 0.002 0.0051 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0146 0.0803 0.1388
Toxoplasma gondii cathepsin CPL 0.002 0.0051 0.0187
Onchocerca volvulus 0.0146 0.0803 0.1758
Brugia malayi beta-lactamase family protein 0.0146 0.0803 0.1758
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0803 0.0803
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0113 0.0226
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0017 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0392 0.4797
Entamoeba histolytica Ran family GTPase 0.0046 0.0203 0.1112
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0027 0.0047
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Loa Loa (eye worm) cysteine protease 0.002 0.0051 0.007
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0793 0.1371
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0113 0.0198
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0054 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.1042 0.1042
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0017 0.0033 0.0262
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0203 0.0336
Onchocerca volvulus 0.0034 0.0134 0.0272
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0032 0.0032
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.037 0.1252
Onchocerca volvulus 0.002 0.0051 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0113 0.0178
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0134 0.0215
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0044 0.0196 0.0342
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0044 0.0196 0.0342
Echinococcus multilocularis ubiquitin specific protease 41 0.0113 0.0605 0.0605
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0134 0.0234
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0793 0.1371
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0134 0.0234
Echinococcus multilocularis microtubule associated protein 2 0.07 0.4121 0.4121
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Echinococcus granulosus phd:f box containing protein 0.0016 0.0027 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0051 0.007
Echinococcus granulosus cathepsin l1 0.002 0.0051 0.009
Echinococcus multilocularis neutral amino acid transporter A 0.0766 0.4515 0.4515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0027 0.0047
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Brugia malayi hypothetical protein 0.0014 0.0017 0.0012
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0803 0.977
Brugia malayi CXXC zinc finger family protein 0.006 0.0287 0.0611
Echinococcus granulosus G protein coupled receptor 139 0.0034 0.0134 0.0234
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0027 0.0027
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0044 0.0196 0.0342
Brugia malayi hypothetical protein 0.0026 0.0086 0.0165
Loa Loa (eye worm) hypothetical protein 0.0091 0.0472 0.0808
Schistosoma mansoni hypothetical protein 0.0848 0.5005 0.8757
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0113 0.0178
Loa Loa (eye worm) glutathione reductase 0.0039 0.0166 0.0272
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0803 0.1388
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0027 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0113 0.0226
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0051
Mycobacterium tuberculosis Conserved protein 0.0146 0.0803 0.144
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0134 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0605 0.2072
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Onchocerca volvulus 0.0034 0.0134 0.0272
Onchocerca volvulus 0.002 0.0051 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0113 0.0178
Onchocerca volvulus 0.005 0.0228 0.0481
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0044 0.0196 0.0342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Trypanosoma brucei importin beta-1 subunit, putative 0.0091 0.0472 0.5817
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0134 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0027 0.0034
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.009 0.0469 0.0831
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0497
Brugia malayi follicle stimulating hormone receptor 0.0034 0.0134 0.0272
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0134 0.0234
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0803 0.2764
Plasmodium falciparum phosphodiesterase delta, putative 0.0044 0.0196 0.3992
Onchocerca volvulus 0.002 0.0051 0.0089
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.1042 0.1822
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.081 0.1417
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0203 0.0425
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0113 0.0226
Echinococcus multilocularis somatostatin receptor 0.0034 0.0134 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0308 0.054
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0044 0.0196 0.0342
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0803 0.9901
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0811 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.1042 0.2287
Brugia malayi hypothetical protein 0.0017 0.0031 0.0043
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.1389 0.1389
Echinococcus multilocularis transportin 1 0.0017 0.0033 0.0033
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0027 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.0645
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0017 0.0012
Schistosoma mansoni coup transcription factor 0.0031 0.0113 0.0198
Brugia malayi G protein-coupled receptor 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0803 0.144
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0351 0.4291
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0134 0.0134
Echinococcus granulosus neuropeptide FF receptor 2 0.0034 0.0134 0.0234
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.0203 0.4146
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0196 0.2322
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0034 0.0134 0.0234
Schistosoma mansoni ran 0.0046 0.0203 0.0355
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0166 0.195
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.07 0.1224
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0162 0.1893
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0044 0.0196 0.2322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.1733 0.6009
Loa Loa (eye worm) ctsf protein 0.002 0.0051 0.007
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0196 0.2322
Brugia malayi hypothetical protein 0.0034 0.0134 0.0272
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0032 0.0057
Schistosoma mansoni importin-beta 2 0.0017 0.0033 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0141
Plasmodium vivax JmjC domain containing protein 0.0016 0.0027 0.0189
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0034 0.0134 0.0215
Loa Loa (eye worm) TYRA-2 protein 0.0034 0.0134 0.0215
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0034 0.0134 0.0272
Brugia malayi Melatonin receptor type 1A 0.0034 0.0134 0.0272
Schistosoma mansoni amine GPCR 0.0034 0.0134 0.0234
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0141
Mycobacterium tuberculosis Probable oxidoreductase 0.01 0.0529 0.094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0113 0.0178
Echinococcus multilocularis neutral amino acid transporter A 0.0766 0.4515 0.4515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0392 0.4797
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.0203 0.0909
Onchocerca volvulus 0.0031 0.0113 0.0226
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0051 0.009
Onchocerca volvulus 0.0034 0.0134 0.0272
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0162 0.0162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0196 0.0875
Loa Loa (eye worm) hypothetical protein 0.0364 0.2111 0.3681
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0364 0.2111 0.3694
Schistosoma mansoni nuclear receptor 0.0014 0.0017 0.0029
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0044 0.0196 0.0645
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0313 0.0548
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0308 0.054
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0034 0.0134 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0196 0.2322
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0089
Schistosoma mansoni hypothetical protein 0.005 0.0228 0.0399
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0134 0.0234
Toxoplasma gondii exonuclease III APE 0.0039 0.0162 0.0713

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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