Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0725 | 0.2677 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0188 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0096 | 0.0188 | 0.0702 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0096 | 0.0188 | 0.5 |
Toxoplasma gondii | peptidase family M13 protein | 0.0096 | 0.0188 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0725 | 0.2677 | 1 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1127 | 0.0958 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0096 | 0.0188 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0725 | 0.2677 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0188 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0188 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.2575 | 1 | 1 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0725 | 0.2677 | 0.2612 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0096 | 0.0188 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0096 | 0.0007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.