Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein patched | 0.0055 | 0.0127 | 0.0601 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0045 | 0.0079 | 0.1703 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | cAMP phosphodiesterase A, putative | 0.0045 | 0.0079 | 0.1113 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0055 | 0.0127 | 0.0601 |
Onchocerca volvulus | 0.0053 | 0.0122 | 0.909 | |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0178 | 0.0892 |
Giardia lamblia | DINP protein human, muc B family | 0.0041 | 0.0059 | 0.0206 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0055 | 0.0127 | 0.0601 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0059 | 0.0705 |
Echinococcus granulosus | dna polymerase eta | 0.0068 | 0.0196 | 0.0999 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0108 | 0.061 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0133 | 0.0524 | 1 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0133 | 0.0524 | 0.2929 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0098 | 0.035 | 0.1889 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0225 | 0.0991 | 0.1361 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0062 | 0.0166 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0068 | 0.0196 | 0.3457 |
Echinococcus granulosus | tumor protein p63 | 0.0375 | 0.1755 | 1 |
Brugia malayi | hypothetical protein | 0.0181 | 0.077 | 0.5066 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0059 | 0.0705 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.0059 | 0.0705 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0034 | 0.0023 | 0.004 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0178 | 0.0936 |
Mycobacterium ulcerans | 3-phosphoshikimate 1-carboxyvinyltransferase | 0.0563 | 0.2711 | 0.2694 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1703 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1703 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0059 | 0.0204 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.0059 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0079 | 0.036 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0036 | 0.0127 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0325 | 0.1503 | 1 |
Giardia lamblia | Hypothetical protein | 0.0045 | 0.0079 | 0.0326 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0036 | 0.0075 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1703 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.037 | 0.1732 | 1 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0045 | 0.0079 | 0.036 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0055 | 0.0127 | 0.0609 |
Echinococcus granulosus | geminin | 0.0353 | 0.1643 | 0.9357 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0122 | 0.0576 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.004 | 0.0052 | 0.0108 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Plasmodium falciparum | glutathione reductase | 0.0098 | 0.035 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0249 | 0.1113 | 0.7378 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0178 | 0.0904 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Leishmania major | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1997 | 1 | 1 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0133 | 0.0524 | 1 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0167 | 0.0699 | 0.3973 |
Brugia malayi | glutathione reductase | 0.0098 | 0.035 | 0.2242 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0068 | 0.0196 | 0.1205 |
Brugia malayi | bHLH-PAS transcription factor | 0.004 | 0.0053 | 0.0239 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.037 | 0.1732 | 0.987 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0225 | 0.0991 | 0.1361 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma cruzi | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0034 | 0.0023 | 0.1405 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0127 | 0.0642 |
Brugia malayi | PAS domain containing protein | 0.0054 | 0.0124 | 0.0719 |
Brugia malayi | hypoxia-induced factor 1 | 0.0167 | 0.0699 | 0.4586 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0249 | 0.1113 | 0.6392 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0045 | 0.0079 | 0.1703 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0036 | 0.0074 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0122 | 0.0576 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0059 | 0.0278 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0062 | 0.0166 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Plasmodium falciparum | thioredoxin reductase | 0.0098 | 0.035 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0026 | 0.0061 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0178 | 0.108 |
Echinococcus multilocularis | transfer RNA-Lys | 0.004 | 0.0053 | 0.0171 |
Onchocerca volvulus | 0.0055 | 0.0129 | 1 | |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0045 | 0.0079 | 0.1703 |
Trypanosoma cruzi | cyclic nucleotide phosphodiesterase | 0.0045 | 0.0079 | 0.1113 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0098 | 0.035 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0045 | 0.0079 | 0.1113 |
Echinococcus granulosus | single minded 2 | 0.004 | 0.0053 | 0.0171 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.1434 | 0.7139 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.037 | 0.1732 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0225 | 0.0991 | 0.1361 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0045 | 0.0079 | 0.0415 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.037 | 0.1732 | 0.987 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | PDE1B protein | 0.0045 | 0.0079 | 0.036 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0133 | 0.0524 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.037 | 0.1732 | 0.987 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Mycobacterium tuberculosis | Probable reductase | 0.0225 | 0.0991 | 0.1361 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0098 | 0.035 | 0.6533 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0045 | 0.0079 | 0.0322 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0059 | 0.3529 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0055 | 0.0127 | 0.0601 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0133 | 0.0524 | 0.2891 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0.0127 | 0.7669 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0325 | 0.1503 | 0.8664 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0133 | 0.0524 | 0.2891 |
Giardia lamblia | hypothetical protein | 0.0045 | 0.0079 | 0.0326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0178 | 0.0904 |
Mycobacterium ulcerans | putative regulatory protein | 0.004 | 0.0053 | 0.003 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1703 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.025 | 0.1119 | 0.154 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0045 | 0.0079 | 0.0415 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0045 | 0.0079 | 0.0415 |
Schistosoma mansoni | DNA polymerase eta | 0.0068 | 0.0196 | 0.1013 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Toxoplasma gondii | thioredoxin reductase | 0.0098 | 0.035 | 0.1216 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1703 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.025 | 0.1119 | 0.0207 |
Leishmania major | cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 | 0.0045 | 0.0079 | 0.1113 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0178 | 0.0892 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0225 | 0.0991 | 0.1361 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0045 | 0.0079 | 0.0415 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0178 | 0.0936 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0055 | 0.0129 | 0.0617 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0225 | 0.0991 | 0.1361 |
Brugia malayi | Thioredoxin reductase | 0.0098 | 0.035 | 0.2242 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0178 | 0.0904 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0059 | 0.0204 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0178 | 0.108 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0036 | 0.0074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0178 | 0.0904 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0045 | 0.0079 | 0.1113 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.1434 | 0.7139 | 1 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0146 | 0.0591 | 0.3864 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0059 | 0.0035 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0108 | 0.061 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0262 | 0.1183 | 0.6698 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0041 | 0.0059 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0325 | 0.1503 | 0.8547 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0045 | 0.0079 | 0.1703 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0054 | 0.0124 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.077 | 0.4389 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0133 | 0.0524 | 0.3409 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0045 | 0.0079 | 0.1703 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0068 | 0.0196 | 0.3457 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0098 | 0.035 | 0.1942 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0563 | 0.2711 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0133 | 0.0524 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.1643 | 0.948 |
Chlamydia trachomatis | phosphoshikimate 1-carboxyl vinyltransferase | 0.0563 | 0.2711 | 0.2694 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0524 | 0.2954 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0059 | 0.005 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Loa Loa (eye worm) | STAT protein | 0.0146 | 0.0591 | 0.3347 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1732 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0062 | 0.0166 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0178 | 0.108 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0059 | 0.0705 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0045 | 0.0079 | 0.1113 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.1643 | 0.948 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0045 | 0.0079 | 0.0415 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0059 | 0.0204 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0262 | 0.1183 | 0.6698 |
Schistosoma mansoni | single-minded | 0.0054 | 0.0124 | 0.059 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0055 | 0.0127 | 0.0601 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0059 | 0.0035 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0026 | 0.0052 |
Schistosoma mansoni | patched 1 | 0.0055 | 0.0127 | 0.0609 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.037 | 0.1732 | 0.6357 |
Trypanosoma brucei | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0055 | 0.0127 | 0.0601 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1997 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0325 | 0.1503 | 0.8547 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0079 | 0.036 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.1113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0036 | 0.0075 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.025 | 0.1119 | 0.154 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus multilocularis | protein dispatched 1 | 0.0055 | 0.0127 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0079 | 0.036 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.004 | 0.0052 | 0.0581 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Brugia malayi | CHE-14 protein | 0.0055 | 0.0127 | 0.0741 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0098 | 0.035 | 0.046 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.0059 | 0.0206 |
Leishmania major | trypanothione reductase | 0.0098 | 0.035 | 0.6533 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0079 | 0.4758 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0059 | 0.0204 |
Leishmania major | DNA polymerase eta, putative | 0.0068 | 0.0196 | 0.3457 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0129 | 0.065 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0045 | 0.0079 | 0.0326 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0249 | 0.1113 | 0.6392 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0108 | 0.0529 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.025 | 0.1119 | 0.154 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0122 | 0.0703 |
Leishmania major | DNA polymerase eta, putative | 0.004 | 0.0052 | 0.0581 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.1183 | 0.6797 |
Plasmodium vivax | glutathione reductase, putative | 0.0098 | 0.035 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0041 | 0.0059 | 0.005 |
Echinococcus multilocularis | dna polymerase eta | 0.0068 | 0.0196 | 0.0999 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0196 | 0.1044 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0108 | 0.0529 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0059 | 0.0705 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0045 | 0.0079 | 0.0322 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.0059 | 0.0206 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0045 | 0.0079 | 0.0322 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1997 | 1 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | glutathione reductase | 0.0098 | 0.035 | 0.1942 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0178 | 0.0936 |
Brugia malayi | hypothetical protein | 0.0262 | 0.1183 | 0.7845 |
Echinococcus multilocularis | tumor protein p63 | 0.0375 | 0.1755 | 1 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0098 | 0.035 | 0.1889 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Echinococcus multilocularis | geminin | 0.0353 | 0.1643 | 0.9357 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0133 | 0.0524 | 0.0502 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0045 | 0.0079 | 0.1113 |
Mycobacterium leprae | probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS | 0.0563 | 0.2711 | 0.2798 |
Trypanosoma brucei | trypanothione reductase | 0.0098 | 0.035 | 0.6533 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0045 | 0.0079 | 0.0415 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0026 | 0.0017 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0034 | 0.0023 | 0.1405 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.037 | 0.1732 | 0.987 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0059 | 0.3529 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0062 | 0.0166 | 0.0835 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0055 | 0.0127 | 0.0642 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0178 | 0.0904 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0079 | 0.1113 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0045 | 0.0079 | 0.4758 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0045 | 0.0079 | 0.0207 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.