Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cyclin dependent kinase binding protein, putative | 0.0029 | 0.142 | 0.0966 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Giardia lamblia | Hypothetical protein | 0.0029 | 0.142 | 0.2194 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0029 | 0.142 | 0.1574 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0181 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0118 | 0.6472 | 0.5888 |
Trypanosoma cruzi | cyclin, putative | 0.0118 | 0.6472 | 1 |
Trypanosoma brucei | cyclin 9 | 0.0029 | 0.142 | 0.1536 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0503 | 0.0551 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0006 | 0.0169 | 0.0178 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0118 | 0.6472 | 1 |
Giardia lamblia | Hypothetical protein | 0.0029 | 0.142 | 0.2194 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0029 | 0.142 | 0.1536 |
Giardia lamblia | Cyclin B-like protein | 0.0029 | 0.142 | 0.2194 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0012 | 0.0503 | 0.0764 |
Echinococcus granulosus | cyclins | 0.0118 | 0.6472 | 0.7222 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0029 | 0.142 | 0.1574 |
Echinococcus granulosus | cyclins | 0.0118 | 0.6472 | 0.7222 |
Echinococcus multilocularis | cyclin A3 4 | 0.0029 | 0.142 | 0.1574 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.142 | 0.2183 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.6472 | 1 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0029 | 0.142 | 0.0966 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Entamoeba histolytica | cyclin, putative | 0.0118 | 0.6472 | 1 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Brugia malayi | hypothetical protein | 0.0029 | 0.142 | 0.2183 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0029 | 0.142 | 0.2183 |
Echinococcus granulosus | cyclins | 0.0029 | 0.142 | 0.1576 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.0029 | 0.142 | 0.1536 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Leishmania major | cyclin | 0.0118 | 0.6472 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus granulosus | cyclin y | 0.0029 | 0.142 | 0.1576 |
Trichomonas vaginalis | cyclin B3, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus granulosus | cyclins | 0.0118 | 0.6472 | 0.7222 |
Echinococcus granulosus | Cyclin L1 | 0.0029 | 0.142 | 0.1576 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0503 | 0.0764 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Echinococcus granulosus | cyclin y | 0.0029 | 0.142 | 0.1576 |
Entamoeba histolytica | cyclin family protein | 0.0118 | 0.6472 | 1 |
Schistosoma mansoni | Cyclin fold protein | 0.0029 | 0.142 | 0.1609 |
Trypanosoma brucei | mitotic cyclin | 0.0029 | 0.142 | 0.1536 |
Giardia lamblia | Hypothetical protein | 0.0118 | 0.6472 | 1 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0503 | 0.0552 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.142 | 0.1536 |
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0503 | 0.0764 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Leishmania major | mitotic cyclin, putative | 0.0029 | 0.142 | 0.1536 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0181 | 1 | 1 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.0029 | 0.142 | 0.0966 |
Schistosoma mansoni | cyclin G2 | 0.0029 | 0.142 | 0.1609 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.142 | 0.0966 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0012 | 0.0503 | 0.0563 |
Brugia malayi | Cyclin C | 0.0029 | 0.142 | 0.2183 |
Entamoeba histolytica | cyclin family protein | 0.0118 | 0.6472 | 1 |
Entamoeba histolytica | cyclin C, putative | 0.0029 | 0.142 | 0.1536 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Toxoplasma gondii | cyclin 4, putative | 0.0029 | 0.142 | 0.0966 |
Trichomonas vaginalis | cyclins, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus multilocularis | cyclin B3 1 | 0.0118 | 0.6472 | 0.7211 |
Echinococcus granulosus | cyclin A3 4 | 0.0029 | 0.142 | 0.1576 |
Echinococcus multilocularis | cyclin G2 | 0.0029 | 0.142 | 0.1574 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0029 | 0.142 | 0.1574 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0029 | 0.142 | 0.1609 |
Onchocerca volvulus | 0.0118 | 0.6472 | 1 | |
Echinococcus granulosus | calcium activated potassium channel | 0.0006 | 0.0169 | 0.0178 |
Schistosoma mansoni | cyclin B3 | 0.0118 | 0.6472 | 0.7372 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0118 | 0.6472 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0118 | 0.6472 | 0.5888 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0029 | 0.142 | 0.1536 |
Trichomonas vaginalis | cyclin B, putative | 0.0118 | 0.6472 | 0.5888 |
Entamoeba histolytica | cyclin, putative | 0.0118 | 0.6472 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0029 | 0.142 | 0.1576 |
Onchocerca volvulus | 0.0029 | 0.142 | 0.1536 | |
Leishmania major | cyclin 9, putative | 0.0029 | 0.142 | 0.1536 |
Toxoplasma gondii | hypothetical protein | 0.009 | 0.4865 | 0.4593 |
Trichomonas vaginalis | hypothetical protein | 0.0181 | 1 | 1 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0029 | 0.142 | 0.1536 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.142 | 0.2183 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0029 | 0.142 | 0.1576 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.142 | 0.0966 |
Echinococcus multilocularis | cyclin t1 | 0.0029 | 0.142 | 0.1574 |
Echinococcus multilocularis | Cyclin L1 | 0.0029 | 0.142 | 0.1574 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Schistosoma mansoni | dihydropteridine reductase | 0.0012 | 0.0503 | 0.0563 |
Echinococcus multilocularis | cyclin | 0.0029 | 0.142 | 0.1574 |
Echinococcus multilocularis | cyclin G2 | 0.0029 | 0.142 | 0.1574 |
Plasmodium vivax | cyclin 4, putative | 0.0029 | 0.142 | 0.0966 |
Echinococcus multilocularis | cyclin B | 0.0118 | 0.6472 | 0.7211 |
Trichomonas vaginalis | cyclin D, putative | 0.0118 | 0.6472 | 0.5888 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0181 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.142 | 0.1609 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0118 | 0.6472 | 1 |
Giardia lamblia | Cyclin A | 0.0118 | 0.6472 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0118 | 0.6472 | 1 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0159 | 0.8776 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0118 | 0.6472 | 0.5888 |
Plasmodium falciparum | cyclin 1 | 0.0029 | 0.142 | 0.0966 |
Plasmodium vivax | cyclin homologue, putative | 0.0029 | 0.142 | 0.0966 |
Trypanosoma brucei | cyclin 3 | 0.0029 | 0.142 | 0.1536 |
Plasmodium falciparum | cyclin | 0.0118 | 0.6472 | 0.6285 |
Trichomonas vaginalis | cyclin B, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus granulosus | cyclin t1 | 0.0029 | 0.142 | 0.1576 |
Echinococcus multilocularis | cyclin y | 0.0029 | 0.142 | 0.1574 |
Echinococcus granulosus | cyclin B | 0.0118 | 0.6472 | 0.7222 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0118 | 0.6472 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0163 | 0.8958 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0029 | 0.142 | 0.1576 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0181 | 1 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0118 | 0.6472 | 0.5888 |
Loa Loa (eye worm) | CYL-1 protein | 0.0029 | 0.142 | 0.2183 |
Trypanosoma cruzi | cyclin 6, putative | 0.0118 | 0.6472 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus multilocularis | cyclin k | 0.0029 | 0.142 | 0.1574 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0118 | 0.6472 | 1 |
Echinococcus granulosus | cyclin b3 | 0.0118 | 0.6472 | 0.7222 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0003 | 0.0009 | 0.00000021007 |
Trichomonas vaginalis | cyclins, putative | 0.0118 | 0.6472 | 0.5888 |
Echinococcus multilocularis | cyclin b3 | 0.0118 | 0.6472 | 0.7211 |
Toxoplasma gondii | cyclin dependent kinase binding protein | 0.0029 | 0.142 | 0.0966 |
Onchocerca volvulus | Protein CNPPD1 homolog | 0.0029 | 0.142 | 0.1536 |
Echinococcus granulosus | cyclin B3 1 | 0.0118 | 0.6472 | 0.7222 |
Trichomonas vaginalis | cyclin B, putative | 0.0118 | 0.6472 | 0.5888 |
Trypanosoma cruzi | cyclin, putative | 0.0118 | 0.6472 | 1 |
Echinococcus granulosus | cyclin k | 0.0029 | 0.142 | 0.1576 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0503 | 0.0764 |
Schistosoma mansoni | cyclin k | 0.0029 | 0.142 | 0.1609 |
Echinococcus granulosus | ankyrin repeat protein | 0.0159 | 0.8776 | 0.9796 |
Echinococcus multilocularis | cyclin y | 0.0029 | 0.142 | 0.1574 |
Leishmania major | mitotic cyclin, putative | 0.0029 | 0.142 | 0.1536 |
Echinococcus granulosus | cyclins | 0.0118 | 0.6472 | 0.7222 |
Echinococcus granulosus | cyclin | 0.0029 | 0.142 | 0.1576 |
Schistosoma mansoni | cyclin d | 0.0029 | 0.142 | 0.1609 |
Schistosoma mansoni | cyclin l | 0.0029 | 0.142 | 0.1609 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0012 | 0.0503 | 0.0764 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0118 | 0.6472 | 1 |
Trypanosoma cruzi | cyclin 9, putative | 0.0029 | 0.142 | 0.1536 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.0029 | 0.142 | 0.1536 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0003 | 0.0009 | 0.00000020975 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Trichomonas vaginalis | cyclins, putative | 0.0118 | 0.6472 | 0.5888 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0029 | 0.142 | 0.2183 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0118 | 0.6472 | 0.7211 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0181 | 1 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0181 | 1 | 1 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0181 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0163 | 0.8972 | 1 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0029 | 0.142 | 0.1609 |
Giardia lamblia | Cyclin fold protein 1, putative | 0.0029 | 0.142 | 0.2194 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0503 | 0.0764 |
Loa Loa (eye worm) | cyclin C | 0.0029 | 0.142 | 0.2183 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0159 | 0.8776 | 0.9781 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0029 | 0.142 | 0.0966 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0029 | 0.142 | 0.2183 |
Echinococcus multilocularis | cyclins | 0.0118 | 0.6472 | 0.7211 |
Onchocerca volvulus | Cyclin L homolog | 0.0029 | 0.142 | 0.1536 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0029 | 0.142 | 0.1576 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0029 | 0.142 | 0.1576 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0118 | 0.6472 | 1 |
Toxoplasma gondii | cyclin domain protein, cyclin H family protein | 0.0029 | 0.142 | 0.0966 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.6472 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Echinococcus granulosus | cyclins | 0.0118 | 0.6472 | 0.7222 |
Brugia malayi | hypothetical protein | 0.0029 | 0.142 | 0.2183 |
Schistosoma mansoni | cyclins | 0.0118 | 0.6472 | 0.7372 |
Trichomonas vaginalis | cyclins, putative | 0.0118 | 0.6472 | 0.5888 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.142 | 0.1609 |
Schistosoma mansoni | cyclin B | 0.0118 | 0.6472 | 0.7372 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Schistosoma mansoni | cyclin G | 0.0029 | 0.142 | 0.1609 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0118 | 0.6472 | 0.7222 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0029 | 0.142 | 0.2183 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0029 | 0.142 | 0.1536 |
Onchocerca volvulus | Cyclin L homolog | 0.0029 | 0.142 | 0.1536 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.