Detailed information for compound 83386

Basic information

Technical information
  • TDR Targets ID: 83386
  • Name: (2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]am ino]-3-hydroxypropanoic acid
  • MW: 218.25 | Formula: C9H18N2O4
  • H donors: 4 H acceptors: 4 LogP: -2.98 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)O)CO)N)C
  • InChi: 1S/C9H18N2O4/c1-3-5(2)7(10)8(13)11-6(4-12)9(14)15/h5-7,12H,3-4,10H2,1-2H3,(H,11,13)(H,14,15)/t5-,6-,7-/m0/s1
  • InChiKey: TWVKGYNQQAUNRN-ACZMJKKPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[[(2S,3S)-2-amino-3-methyl-pentanoyl]amino]-3-hydroxy-propanoic acid
  • (2S)-2-[[(2S,3S)-2-amino-3-methyl-1-oxopentyl]amino]-3-hydroxypropanoic acid
  • (2S)-2-[[(2S,3S)-2-azanyl-3-methyl-pentanoyl]amino]-3-hydroxy-propanoic acid
  • (2S)-2-[[(2S,3S)-2-amino-3-methyl-pentanoyl]amino]-3-hydroxy-propionic acid
  • (2S)-2-[[(2S,3S)-2-azaniumyl-3-methylpentanoyl]amino]-3-hydroxypropanoate
  • (2S)-2-[[(2S,3S)-2-azaniumyl-3-methyl-pentanoyl]amino]-3-hydroxy-propanoate
  • (2S)-2-[[(2S,3S)-2-ammonio-3-methyl-1-oxopentyl]amino]-3-hydroxypropanoate
  • (2S)-2-[[(2S,3S)-2-ammonio-3-methyl-pentanoyl]amino]-3-hydroxy-propionate
  • ZINC02575119

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0085 0.0766 0.4313
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0081 0.0343
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0081 0.0343
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.042 0.2308
Echinococcus multilocularis microtubule associated protein 2 0.0744 0.8402 0.8402
Echinococcus multilocularis para nitrobenzyl esterase 0.0025 0.0075 0.0075
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0122 0.1199 0.1199
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0146 0.1473 0.8394
Brugia malayi nuclear receptor NHR-88 0.018 0.1869 0.2967
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0762 0.1209
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0146 0.1473 0.8394
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Plasmodium falciparum LCCL domain-containing protein 0.0063 0.0508 0.9541
Echinococcus granulosus GPCR family 2 0.0047 0.033 0.033
Schistosoma mansoni nuclear hormone receptor 0.018 0.1869 0.1869
Schistosoma mansoni memapsin-2 (A01 family) 0.0465 0.5171 0.5171
Echinococcus granulosus carboxylesterase 5A 0.0149 0.1508 0.1508
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0081 0.0294
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0081 0.0343
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0122 0.1199 1
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0051 0.0372 0.2008
Echinococcus granulosus lamin 0.0084 0.0762 0.0762
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.018 0.1869 0.2967
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0497 0.0497
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0066 0.1234
Schistosoma mansoni thyroid hormone receptor 0.0316 0.3441 0.3441
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0025 0.0075 0.0075
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0066 0.1234
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.1199 0.4181
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.1002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.018 0.1869 0.2967
Echinococcus multilocularis serotonin transporter 0.0169 0.1741 0.1741
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0812 0.0812
Echinococcus multilocularis GPCR, family 2 0.0047 0.033 0.033
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0122 0.1199 0.1199
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0081 0.0294
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0146 0.1473 0.8394
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0134 0.0654
Schistosoma mansoni loxhd1 0.0063 0.0508 0.0508
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.0184
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0122 0.1199 0.1903
Loa Loa (eye worm) hypothetical protein 0.0133 0.1327 0.2107
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0295
Schistosoma mansoni Tr4/Tr2 (homologue) 0.018 0.1869 0.1869
Leishmania major farnesyltransferase beta subunit 0.0021 0.0027 0.003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.018 0.1869 0.1869
Echinococcus multilocularis expressed conserved protein 0.009 0.0827 0.0827
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0066 0.0568
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0812 0.0812
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.018 0.1869 0.2967
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.018 0.1869 0.2967
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0063 0.0508 0.4132
Echinococcus multilocularis ecdysone induced protein 78C 0.018 0.1869 0.1869
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.042 0.1465
Trypanosoma cruzi DNA topoisomerase II, putative 0.0058 0.0457 0.2499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.1199 0.4181
Brugia malayi Nuclear hormone receptor E75 0.0081 0.0725 0.1151
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.018 0.1869 0.1869
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0182
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0528 0.4408
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Trypanosoma cruzi lanosterol synthase, putative 0.0153 0.1559 0.8898
Schistosoma mansoni hypothetical protein 0.0026 0.0081 0.0081
Onchocerca volvulus 0.0029 0.0116 0.0215
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0497 0.0497
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0236 0.4438
Echinococcus granulosus expressed conserved protein 0.009 0.0827 0.0827
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.042 0.2285
Schistosoma mansoni BC026374 protein (S09 family) 0.0025 0.0075 0.0075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0186 0.0186
Loa Loa (eye worm) doublecortin family protein 0.0063 0.0508 0.0806
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Schistosoma mansoni lamin 0.0084 0.0762 0.0762
Brugia malayi Nuclear hormone receptor family member nhr-41 0.018 0.1869 0.2967
Schistosoma mansoni nuclear receptor 0.0081 0.0725 0.0725
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0236 0.1217
Brugia malayi cytochrome P450 0.0026 0.0081 0.0128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.018 0.1869 0.1869
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Giardia lamblia DNA topoisomerase II 0.0062 0.0499 0.4059
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0021 0.0027 0.0027
Mycobacterium ulcerans oxidoreductase 0.012 0.1176 0.6666
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0236 1
Mycobacterium leprae putative cytochrome p450 0.0146 0.1473 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.018 0.1869 0.1869
Loa Loa (eye worm) TAR-binding protein 0.0123 0.1207 0.1916
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0146 0.1473 0.8402
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0247 0.0861
Echinococcus multilocularis expressed protein 0.0364 0.3994 0.3994
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0247 0.1279
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.018 0.1869 0.1869
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0021 0.0027 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0146 0.1473 0.8402
Schistosoma mansoni hypothetical protein 0.0047 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0563 0.6299 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0025 0.0075 0.0262
Loa Loa (eye worm) hypothetical protein 0.0484 0.5386 0.8551
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0021 0.0027 0.0027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0123 0.1207 0.1916
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0017 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0123 0.1207 0.1207
Schistosoma mansoni hypothetical protein 0.0879 0.996 0.996
Brugia malayi Nuclear hormone receptor family member nhr-3 0.018 0.1869 0.2967
Brugia malayi Nuclear hormone receptor family member nhr-19 0.018 0.1869 0.2967
Loa Loa (eye worm) histone methyltransferase 0.002 0.002 0.0032
Schistosoma mansoni retinoid-x-receptor (RXR) 0.018 0.1869 0.1869
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0081 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.042 0.363
Schistosoma mansoni laminin gamma-3 chain 0.0023 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0146 0.1473 0.8402
Schistosoma mansoni hypothetical protein 0.0047 0.033 0.033
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0081 0.0343
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0027 0.0045
Brugia malayi Cytochrome P450 family protein 0.0035 0.019 0.0302
Trypanosoma cruzi DNA topoisomerase II, putative 0.0058 0.0457 0.2499
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0122 0.1199 0.1199
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Schistosoma mansoni cell polarity protein 0.0023 0.0055 0.0055
Brugia malayi Carboxylesterase family protein 0.0149 0.1508 0.2394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.018 0.1869 0.2967
Brugia malayi photoreceptor-specific nuclear receptor 0.018 0.1869 0.2967
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Schistosoma mansoni intermediate filament proteins 0.0084 0.0762 0.0762
Loa Loa (eye worm) CYP4Cod1 0.0035 0.019 0.0302
Brugia malayi conserved hypotetical protein 0.0081 0.0725 0.1151
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0133 0.1327 0.756
Schistosoma mansoni lipoxygenase 0.0063 0.0508 0.0508
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0501 0.0796
Onchocerca volvulus 0.0029 0.0116 0.0215
Brugia malayi Steroid receptor seven-up type 2 0.018 0.1869 0.2967
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0247 0.1262
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0146 0.1473 0.8402
Echinococcus multilocularis dna polymerase kappa 0.004 0.0247 0.0247
Schistosoma mansoni hypothetical protein 0.0879 0.996 0.996
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0136 0.1356 0.1356
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) nuclear hormone receptor 0.0081 0.0725 0.1151
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0812 0.0812
Toxoplasma gondii histone lysine methyltransferase SET1 0.0119 0.1157 1
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0133 0.1327 0.1327
Trichomonas vaginalis set domain proteins, putative 0.0266 0.2867 1
Brugia malayi hypothetical protein 0.0063 0.0508 0.0806
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0894 0.746
Schistosoma mansoni hypothetical protein 0.004 0.0243 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Onchocerca volvulus 0.0025 0.0075 0.0139
Brugia malayi hypothetical protein 0.0035 0.019 0.0301
Loa Loa (eye worm) solute carrier family 6 member 4 0.0169 0.1741 0.2764
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0021 0.0027 0.0027
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0133 0.1327 0.2107
Loa Loa (eye worm) hypothetical protein 0.0043 0.0286 0.0454
Echinococcus granulosus Niemann Pick C1 protein 0.0192 0.2006 0.2006
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0169 0.1741 0.1741
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0122 0.0122
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0051 0.0372 0.2008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.151 0.2396
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0528 0.2935
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.018 0.1869 0.2967
Schistosoma mansoni hypothetical protein 0.0063 0.0508 0.0508
Leishmania major lanosterol 14-alpha-demethylase, putative 0.017 0.1749 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0006 0.0009
Loa Loa (eye worm) cytochrome P450 0.0026 0.0081 0.0128
Loa Loa (eye worm) hypothetical protein 0.0169 0.1741 0.2764
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.042 0.2285
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0256 0.0256
Brugia malayi Pre-SET motif family protein 0.0234 0.2495 0.3961
Brugia malayi nuclear hormone receptor 0.0081 0.0725 0.1151
Leishmania major cytochrome p450-like protein 0.0026 0.0081 0.0343
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0081 0.0294
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0099 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.1223 0.1942
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0021 0.0027 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0081 0.0725 0.0725
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.003 0.0259
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0081 0.0725 0.1346
Loa Loa (eye worm) hypothetical protein 0.0149 0.1508 0.2394
Echinococcus granulosus pikachurin 0.0023 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0096 0.0894 0.142
Brugia malayi nuclear hormone receptor family member nhr-6 0.0081 0.0725 0.1151
Echinococcus multilocularis dnaJ subfamily B 0.0882 1 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0122 0.1199 0.6816
Loa Loa (eye worm) norepinephrine transporter 0.0169 0.1741 0.2764
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0099 0.0928 0.1473
Echinococcus granulosus thyroid hormone receptor alpha 0.0081 0.0725 0.0725
Onchocerca volvulus 0.0062 0.0501 0.093
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0029 0.0116 0.0116
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0021 0.0027 0.0223
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0896 0.3124
Plasmodium vivax SET domain protein, putative 0.0035 0.0186 0.3494
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.033 0.033
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0528 0.0839
Echinococcus multilocularis Polycystic kidney disease protein 0.0063 0.0508 0.0508
Plasmodium falciparum transporter, putative 0.0029 0.0116 0.2177
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0186 0.0186
Plasmodium vivax geranylgeranyltransferase, putative 0.0021 0.0027 0.05
Brugia malayi MAP kinase sur-1 0.0055 0.042 0.0667
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.042 0.1465
Schistosoma mansoni hypothetical protein 0.0882 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0247 0.1279
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1199 0.6816
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.018 0.1869 0.1869
Onchocerca volvulus 0.0063 0.0508 0.0943
Brugia malayi Nuclear hormone receptor family member nhr-25 0.018 0.1869 0.2967
Echinococcus granulosus FTZ F1 alpha 0.018 0.1869 0.1869
Echinococcus granulosus BC026374 protein S09 family 0.0025 0.0075 0.0075
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0116 0.0116
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0378 0.4161 0.4161
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0528 0.2935
Echinococcus granulosus ecdysone induced protein 78C 0.018 0.1869 0.1869
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0065 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Onchocerca volvulus 0.0035 0.0186 0.0345
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0021 0.0027 0.023
Loa Loa (eye worm) TOPoisomerase family member 0.0065 0.0532 0.0845
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0021 0.0027 0.05
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0236 0.1825
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0021 0.0027 0.0093
Loa Loa (eye worm) hypothetical protein 0.0063 0.0508 0.0806
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0134 0.0654
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0963 0.153
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0497 0.4297
Schistosoma mansoni cpg binding protein 0.0062 0.0501 0.0501
Brugia malayi Carboxylesterase family protein 0.0025 0.0075 0.0119
Echinococcus multilocularis pikachurin 0.0023 0.0055 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0186 0.0186
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0116 0.0116
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0081 0.0725 0.0725
Loa Loa (eye worm) hypothetical protein 0.0169 0.1741 0.2764
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0066 0.0227
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Echinococcus granulosus expressed protein 0.0364 0.3994 0.3994
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0186 0.1607
Brugia malayi TAR-binding protein 0.0123 0.1207 0.1916
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.018 0.1869 0.1869
Brugia malayi nuclear receptor RXR 0.0081 0.0725 0.1151
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0497 0.2754
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.1002
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0528 0.0839
Loa Loa (eye worm) steroid hormone receptor 0.018 0.1869 0.2967
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.002 0.002
Schistosoma mansoni rab6-interacting 0.0063 0.0508 0.0508
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.2718
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0006
Brugia malayi small heat shock protein 0.0563 0.6299 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.019 0.0931
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0075 0.0075
Echinococcus granulosus ubiquitin specific protease 41 0.0122 0.1199 0.1199
Schistosoma mansoni hypothetical protein 0.0047 0.033 0.033
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.042 0.2285
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0021 0.0027 0.003
Brugia malayi Carboxylesterase family protein 0.0025 0.0075 0.0119
Brugia malayi ecdysone receptor 0.0081 0.0725 0.1151
Echinococcus multilocularis tar DNA binding protein 0.0123 0.1207 0.1207
Echinococcus granulosus intermediate filament protein 0.0084 0.0762 0.0762
Plasmodium falciparum geranylgeranyltransferase, putative 0.0021 0.0027 0.05
Schistosoma mansoni sodium-dependent amino acid transporter 0.0029 0.0116 0.0116
Trypanosoma cruzi lanosterol synthase, putative 0.0153 0.1559 0.8898
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.017 0.1749 1
Toxoplasma gondii hypothetical protein 0.0029 0.0116 0.1002
Loa Loa (eye worm) hypothetical protein 0.0122 0.1199 0.1903
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0116 0.0116
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0122 0.1199 0.1199
Onchocerca volvulus 0.0169 0.1741 0.3232
Echinococcus multilocularis neurogenic locus notch protein 0.0023 0.0055 0.0055
Trichomonas vaginalis spcc417.12 protein, putative 0.0025 0.0075 0.0262
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0084 0.0762 0.1209
Leishmania major geranylgeranyltransferase, putative 0.0021 0.0027 0.003
Schistosoma mansoni RAR-like nuclear receptor 0.018 0.1869 0.1869
Echinococcus multilocularis acetylcholinesterase 0.0149 0.1508 0.1508
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0236 0.0236
Trypanosoma brucei protein kinase, putative 0.0055 0.042 0.2308
Loa Loa (eye worm) hypothetical protein 0.0083 0.0744 0.1181
Schistosoma mansoni ap endonuclease 0.0039 0.0236 0.0236
Echinococcus granulosus retinoic acid receptor rxr beta a 0.018 0.1869 0.1869
Brugia malayi Nuclear hormone receptor family member nhr-25 0.018 0.1869 0.2967
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0133 0.1327 0.7553
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0081 0.0725 0.1151
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0099 0.0928 0.1473
Brugia malayi hypothetical protein 0.0025 0.0075 0.0119
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0027 0.0093
Trichomonas vaginalis DNA topoisomerase II, putative 0.0065 0.0532 0.1857
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0066 0.1234
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0021 0.0027 0.0093
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0081 0.0725 0.0725
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0081 0.0343
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.2718
Echinococcus multilocularis sterol regulatory element binding protein 0.0096 0.0896 0.0896
Brugia malayi Carboxylesterase family protein 0.0025 0.0075 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.018 0.1869 0.2967
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0894 0.0894
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0087
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.019 0.0302
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0812 0.0812
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0065 0.0532 0.0845
Brugia malayi polk-prov protein 0.003 0.0134 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0186 0.0186
Brugia malayi ecdysteroid receptor 0.0484 0.5386 0.8551
Entamoeba histolytica hypothetical protein 0.0035 0.019 0.1582
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0378 0.4161 0.6605
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1199 0.6807
Echinococcus multilocularis cpg binding protein 0.0065 0.0542 0.0542
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.042 0.2308
Plasmodium falciparum DNA gyrase subunit B 0.0021 0.003 0.0563
Loa Loa (eye worm) hypothetical protein 0.005 0.0368 0.0584
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0146 0.1473 0.8394
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0081 0.0343
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.1002
Brugia malayi CXXC zinc finger family protein 0.0062 0.0501 0.0796
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.018 0.1869 0.1869
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0081 0.0343
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0021 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0146 0.1473 0.8394
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0453 0.5034 0.5034
Onchocerca volvulus 0.0025 0.0075 0.0139
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0236 0.1217
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0182
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.017 0.1749 1
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0928 0.1473
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0146 0.1473 0.8402
Brugia malayi steroid hormone receptor 0.018 0.1869 0.2967
Brugia malayi hypothetical protein 0.0081 0.0725 0.1151
Echinococcus multilocularis FTZ F1 alpha 0.018 0.1869 0.1869
Schistosoma mansoni coup transcription factor 0.018 0.1869 0.1869
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0039 0.0238 0.0377
Loa Loa (eye worm) nuclear receptor NHR-67 0.0081 0.0725 0.1151
Brugia malayi Probable DNA topoisomerase II 0.0065 0.0532 0.0845
Loa Loa (eye worm) abnormal epIthelia family member 0.0023 0.0055 0.0087
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0308 0.0488
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0236 0.1972
Schistosoma mansoni tar DNA-binding protein 0.0123 0.1207 0.1207
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0146 0.1473 0.8394
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0021 0.0027 0.0093
Loa Loa (eye worm) serotonin transporter b 0.0169 0.1741 0.2764
Loa Loa (eye worm) hypothetical protein 0.0099 0.0928 0.1473
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0508 0.1771
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0006 0.0009
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.033 0.033
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0075 0.0311
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0122 0.1199 0.1199
Brugia malayi Nuclear hormone receptor family member nhr-1 0.018 0.1869 0.2967
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.019 0.0949
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0102 0.0963 0.0963
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0133 0.1327 0.7548
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.018 0.1869 0.1869
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0081 0.0725 0.1346
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.0184
Echinococcus granulosus dna polymerase kappa 0.004 0.0247 0.0247
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0023 0.0055 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0169 0.1741 0.2764
Loa Loa (eye worm) DR-78 0.0081 0.0725 0.1151
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0006 0.0006
Schistosoma mansoni polycystin 1-related 0.0063 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0247 0.0861
Schistosoma mansoni cpg binding protein 0.0065 0.0542 0.0542
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0528 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-49 0.018 0.1869 0.2967
Schistosoma mansoni hypothetical protein 0.004 0.0243 0.0243
Toxoplasma gondii exonuclease III APE 0.0039 0.0236 0.2042
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Trypanosoma brucei unspecified product 0.0034 0.0173 0.0875
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0247 0.1279
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0378 0.4161 0.6605
Brugia malayi hypothetical protein 0.0063 0.0508 0.0806
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.019 0.019
Schistosoma mansoni nuclear receptor 0.0081 0.0725 0.0725
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0146 0.1473 0.8394
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0508 0.0508
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0099 0.0928 0.0928
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0133 0.1327 0.7553
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0021 0.0027 0.0027
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0116 0.0116
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0116 0.0116
Loa Loa (eye worm) carboxylesterase 0.0025 0.0075 0.0119
Echinococcus multilocularis neuroligin 0.0025 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0146 0.1473 0.8402
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0508 0.0508
Schistosoma mansoni ap endonuclease 0.0039 0.0236 0.0236
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0186 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0146 0.1473 0.8402
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0215 0.0215
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0236 0.1244
Entamoeba histolytica DNA topoisomerase II, putative 0.0065 0.0532 0.4441
Schistosoma mansoni lamin 0.0084 0.0762 0.0762
Brugia malayi Carboxylesterase family protein 0.0025 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Toxoplasma gondii DNA topoisomerase 2, putative 0.0065 0.0532 0.46
Brugia malayi hypothetical protein 0.0029 0.0116 0.0184
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.003 0.005
Echinococcus granulosus cpg binding protein 0.0065 0.0542 0.0542
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0029 0.0116 0.5374
Echinococcus granulosus neurogenic locus notch protein 0.0023 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0087
Loa Loa (eye worm) hypothetical protein 0.0096 0.0896 0.1422
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0021 0.0027 0.05
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0497 0.0497
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0247 0.1262
Brugia malayi nuclear hormone receptor 0.018 0.1869 0.2967
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0058 0.0457 0.2522
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0066 0.0257
Schistosoma mansoni microtubule-associated protein tau 0.0744 0.8402 0.8402
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0236 0.12
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0029 0.0116 0.0184
Brugia malayi laminin-like protein K08C7.3 precursor 0.0023 0.0055 0.0087
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.0184
Echinococcus multilocularis geminin 0.0879 0.996 0.996
Onchocerca volvulus 0.0063 0.0508 0.0943
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.019 0.0302
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2495 0.3961
Plasmodium vivax multidomain scavenger receptor, putative 0.0063 0.0508 0.9541
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0021 0.0027 0.0093
Plasmodium vivax DNA gyrase subunit B, putative 0.0021 0.003 0.0563
Onchocerca volvulus 0.0084 0.0762 0.1414
Brugia malayi Nuclear hormone receptor family member nhr-31 0.018 0.1869 0.2967
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0047 0.0327 0.0606
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0066 0.0227
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0025 0.0075 0.0075
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0081 0.0696
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0215 0.0215
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0133 0.1327 0.1327
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0146 0.1473 0.8394
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0021 0.0027 0.05
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0236 0.1206
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0075 0.0075
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0146 0.1473 0.8394
Echinococcus granulosus Polycystic kidney disease protein 0.0063 0.0508 0.0508
Schistosoma mansoni gliotactin 0.0025 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Schistosoma mansoni hypothetical protein 0.004 0.0243 0.0243
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0894 0.0894
Schistosoma mansoni hypothetical protein 0.0136 0.1356 0.1356
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0027 0.0093
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.033 0.0524
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0256 0.0256
Echinococcus granulosus sterol regulatory element binding protein 0.0096 0.0896 0.0896
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.018 0.1869 0.2967
Loa Loa (eye worm) acetylcholinesterase 1 0.0149 0.1508 0.2394
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0508 0.0508
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.018 0.1869 0.1869
Leishmania major DNA topoisomerase ii 0.0058 0.0457 0.2522
Schistosoma mansoni neuroligin 3 (S09 family) 0.0025 0.0075 0.0075
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0236 0.4438
Schistosoma mansoni lipoxygenase 0.0175 0.1811 0.1811
Schistosoma mansoni nuclear hormone receptor 0.0081 0.0725 0.0725
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0021 0.0027 0.0042
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0096 0.0896 0.1422
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.042 0.2285
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0006 0.0006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.042 0.0667
Loa Loa (eye worm) hypothetical protein 0.0102 0.0963 0.153
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0021 0.0027 0.0042
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0508 0.1771
Schistosoma mansoni tar DNA-binding protein 0.0123 0.1207 0.1207
Echinococcus multilocularis 0.0026 0.0081 0.0081
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0116 0.0116
Onchocerca volvulus 0.0266 0.2867 0.5323
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.0184
Echinococcus granulosus nuclear receptor nhr 48 0.0081 0.0725 0.0725
Loa Loa (eye worm) hypothetical protein 0.0063 0.0508 0.0806
Brugia malayi nuclear receptor NHR-88 0.0081 0.0725 0.1151
Loa Loa (eye worm) carboxylesterase 0.0149 0.1508 0.2394
Schistosoma mansoni hypothetical protein 0.0108 0.1037 0.1037
Brugia malayi RNA recognition motif domain containing protein 0.0123 0.1207 0.1916
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0021 0.0027 0.0027
Schistosoma mansoni steroid hormone receptor ad4bp 0.018 0.1869 0.1869
Echinococcus granulosus serotonin transporter 0.0169 0.1741 0.1741
Schistosoma mansoni nuclear hormone receptor 0.0081 0.0725 0.0725
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0027 0.023
Onchocerca volvulus 0.0029 0.0116 0.0215
Loa Loa (eye worm) hypothetical protein 0.0047 0.033 0.0524
Echinococcus multilocularis musashi 0.0084 0.0762 0.0762
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.042 0.042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0812 0.0812
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0146 0.1473 0.8394
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0021 0.0027 0.0027
Echinococcus multilocularis Niemann Pick C1 protein 0.0192 0.2006 0.2006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0152 0.1547 0.1547
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.018 0.1869 0.1869
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0099 0.0928 0.0928
Treponema pallidum sodium- and chloride- dependent transporter 0.0169 0.1741 1
Onchocerca volvulus 0.018 0.1869 0.347
Brugia malayi hypothetical protein 0.0081 0.0725 0.1151
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0065 0.0532 0.0532
Echinococcus granulosus lamin dm0 0.0084 0.0762 0.0762
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0762 0.1209
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.2489 0.3951
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0021 0.0027 0.0223
Onchocerca volvulus 0.0081 0.0725 0.1346
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Echinococcus granulosus neuroligin 0.0025 0.0075 0.0075
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0169 0.1741 0.2764
Echinococcus multilocularis carboxylesterase 5A 0.0149 0.1508 0.1508
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.1223 0.1942
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0146 0.1473 0.8402
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.132 0.132
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.033 0.0524
Leishmania major hypothetical protein, conserved 0.0024 0.0066 0.0257
Leishmania major mitochondrial DNA topoisomerase II 0.0051 0.0372 0.2032
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0528 0.0528
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0133 0.1327 0.756
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.018 0.1869 0.1869
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0021 0.0027 0.0027
Echinococcus granulosus acetylcholinesterase 0.0149 0.1508 0.1508
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0081 0.0725 0.0725
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0236 0.1244
Schistosoma mansoni hypothetical protein 0.0047 0.033 0.033
Leishmania major lanosterol synthase, putative 0.0132 0.1316 0.7494
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0027 0.003
Giardia lamblia Prenyltransferase 0.0021 0.0027 0.0045
Trypanosoma brucei DNA topoisomerase ii 0.0051 0.0372 0.2032
Echinococcus granulosus Protein patched homolog 1 0.0096 0.0896 0.0896
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.033 0.033
Brugia malayi tailless protein 0.0081 0.0725 0.1151
Loa Loa (eye worm) hypothetical protein 0.0039 0.0238 0.0377
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0136 0.1356 0.1356
Schistosoma mansoni slit 0.0023 0.0055 0.0055
Brugia malayi Cytochrome P450 family protein 0.0035 0.019 0.0302
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0236 0.0824
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Schistosoma mansoni acetylcholinesterase 0.0025 0.0075 0.0075
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0021 0.0027 0.0223
Echinococcus multilocularis slit 2 protein 0.0023 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.004 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0042
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.019 0.0949
Brugia malayi Carboxylesterase family protein 0.0149 0.1508 0.2394
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0041 0.0256 0.0406
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0116 0.0184
Brugia malayi Latrophilin receptor protein 2 0.0047 0.033 0.0524
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0497 0.2754
Echinococcus granulosus RUN 0.0063 0.0508 0.0508
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0378 0.4161 0.4161
Schistosoma mansoni tar DNA-binding protein 0.0123 0.1207 0.1207
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0081 0.0343
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.1199 0.4181
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0021 0.0027 0.05
Echinococcus multilocularis lamin dm0 0.0084 0.0762 0.0762
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.017 0.1749 1
Brugia malayi Cytochrome P450 family protein 0.0047 0.0328 0.052
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0149 0.1508 0.1508
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0247 0.1279
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.003 0.0134 0.0213
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.002 0.002
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0894 0.142
Echinococcus multilocularis RUN 0.0063 0.0508 0.0508
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0378 0.4161 0.4161
Brugia malayi hypothetical protein 0.0024 0.0066 0.0105
Schistosoma mansoni cytochrome P450 0.0026 0.0081 0.0081
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0308 0.0488
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0528 0.2913
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.1176 0.6683
Loa Loa (eye worm) hypothetical protein 0.018 0.1869 0.2967
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0116 0.0116
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0497 0.0497
Echinococcus multilocularis ubiquitin specific protease 41 0.0122 0.1199 0.1199
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.151 0.2396
Brugia malayi MH2 domain containing protein 0.0124 0.1223 0.1942
Schistosoma mansoni hypothetical protein 0.0035 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0099 0.0928 0.1473
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0021 0.0027 0.0027
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0027 0.0093
Onchocerca volvulus 0.0081 0.0725 0.1346
Schistosoma mansoni rab6-interacting 0.0063 0.0508 0.0508
Brugia malayi orphan nuclear receptor NR2E1 0.0081 0.0725 0.1151
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0928 0.1473
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0236 0.0824
Echinococcus multilocularis thyroid hormone receptor alpha 0.0316 0.3441 0.3441
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0762 0.1209
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0146 0.1473 0.8394
Echinococcus multilocularis protein patched 0.0096 0.0896 0.0896
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.1199 0.6807
Toxoplasma gondii hypothetical protein 0.0029 0.0116 0.1002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0116 0.0116
Brugia malayi Nuclear hormone receptor E75 0.0081 0.0725 0.1151
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0247 0.1306
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0328 0.052
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.017 0.1749 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.151 0.2396
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0058 0.0457 0.2522
Onchocerca volvulus Bile acid receptor homolog 0.0484 0.5386 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0025 0.0075 0.0262
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0047 0.0327 0.0606
Echinococcus multilocularis BC026374 protein (S09 family) 0.0025 0.0075 0.0075
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.018 0.1869 0.1869
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0081 0.0725 0.0725
Echinococcus granulosus para nitrobenzyl esterase 0.0025 0.0075 0.0075
Schistosoma mansoni zinc finger protein 0.0081 0.0725 0.0725
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0021 0.0027 0.0042
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0116 0.0116
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.018 0.1869 0.1869
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.018 0.1869 0.347
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0528 0.2913
Echinococcus multilocularis protein dispatched 1 0.0102 0.0963 0.0963
Echinococcus granulosus nuclear receptor 2DBD gamma 0.018 0.1869 0.1869
Schistosoma mansoni patched 1 0.0096 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.0099 0.0928 0.1473
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0812 0.1288
Brugia malayi intermediate filament protein 0.0084 0.0762 0.1209
Brugia malayi Nuclear hormone receptor-like 1 0.018 0.1869 0.2967
Onchocerca volvulus 0.0025 0.0075 0.0139
Plasmodium falciparum DNA topoisomerase 2 0.0065 0.0532 1
Echinococcus granulosus microtubule associated protein 2 0.0744 0.8402 0.8402
Entamoeba histolytica hypothetical protein 0.0035 0.019 0.1582
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0075 0.0311
Onchocerca volvulus Protein ultraspiracle homolog 0.018 0.1869 0.347
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0146 0.1473 0.8394
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0146 0.1473 0.8394
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0236 0.0375
Loa Loa (eye worm) hypothetical protein 0.0043 0.0286 0.0454
Brugia malayi nuclear receptor NHR-67 0.0081 0.0725 0.1151
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.042 0.1465
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0133 0.1327 0.1327
Echinococcus multilocularis nuclear receptor nhr 48 0.0081 0.0725 0.0725
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0042
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0146 0.1473 0.8394
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Echinococcus multilocularis acetylcholinesterase 0.0149 0.1508 0.1508
Brugia malayi Cytochrome P450 family protein 0.0026 0.0081 0.0128
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0175 0.1811 0.1811
Loa Loa (eye worm) hypothetical protein 0.0081 0.0725 0.1151
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.042 0.042
Brugia malayi CHE-14 protein 0.0096 0.0896 0.1422
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0065 0.0532 0.0845
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.042 0.3386
Loa Loa (eye worm) carboxylesterase 0.0025 0.0075 0.0119
Entamoeba histolytica hypothetical protein 0.0035 0.019 0.1582
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0236 0.1244
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0247 0.1306
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.042 0.1465
Schistosoma mansoni retinoic acid receptor RXR 0.018 0.1869 0.1869
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.042 0.2308
Echinococcus granulosus tar DNA binding protein 0.0123 0.1207 0.1207
Schistosoma mansoni thyroid hormone receptor 0.0316 0.3441 0.3441
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.017 0.1749 1
Brugia malayi Pre-SET motif family protein 0.0035 0.0186 0.0295
Plasmodium vivax DNA topoisomerase II, putative 0.0065 0.0532 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0146 0.1473 0.8394
Mycobacterium tuberculosis Carboxylesterase LipT 0.0025 0.0075 0.0311
Schistosoma mansoni cpg binding protein 0.0065 0.0542 0.0542
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.018 0.1869 0.1869
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0075 0.0075
Trypanosoma brucei cytochrome P450, putative 0.0035 0.019 0.0976
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0122 0.1199 1
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0173 0.0875
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0081 0.0725 0.0725
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0047 0.0327 0.0606
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0146 0.1473 0.8394
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0812 0.0812
Loa Loa (eye worm) RNA binding protein 0.0123 0.1207 0.1916
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0081 0.0313
Brugia malayi RNA binding protein 0.0123 0.1207 0.1916
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Brugia malayi follicle stimulating hormone receptor 0.0234 0.2489 0.3951
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0146 0.1473 0.8402
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0081 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0123 0.1207 0.1207
Brugia malayi Nuclear hormone receptor family member nhr-40 0.018 0.1869 0.2967
Echinococcus granulosus geminin 0.0879 0.996 0.996
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0236 0.0375
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.019 0.019
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0081 0.0725 0.0725
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0122 0.1199 0.1199
Brugia malayi Doublecortin family protein 0.0063 0.0508 0.0806
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.018 0.1869 0.2967
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0812 0.0812
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0023 0.0055 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0247 0.1306
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Echinococcus granulosus acetylcholinesterase 0.0149 0.1508 0.1508
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0116 0.2177
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0105
Entamoeba histolytica hypothetical protein 0.0035 0.019 0.1582
Echinococcus multilocularis lamin 0.0084 0.0762 0.0762
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0029 0.0116 0.0116
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Onchocerca volvulus 0.0084 0.0762 0.1414
Chlamydia trachomatis DNA gyrase subunit B 0.0035 0.019 1
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0021 0.0027 0.023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-14 0.018 0.1869 0.2967
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0528 0.0528
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0081 0.0725 0.1151
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0021 0.0027 0.0093
Onchocerca volvulus 0.0025 0.0075 0.0139
Brugia malayi nuclear hormone receptor family member odr-7 0.0081 0.0725 0.1151
Brugia malayi hypothetical protein 0.0099 0.0928 0.1473
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0175 0.1811 0.1811
Leishmania major cytochrome p450-like protein 0.0026 0.0081 0.0343
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0081 0.0725 0.0725
Brugia malayi laminin alpha chain 0.0023 0.0055 0.0087
Schistosoma mansoni nuclear receptor nhr-48 0.0081 0.0725 0.0725
Echinococcus granulosus Nuclear hormone receptor HR96 0.0081 0.0725 0.0725
Plasmodium falciparum amino acid transporter, putative 0.0029 0.0116 0.2177
Loa Loa (eye worm) hypothetical protein 0.0099 0.0928 0.1473
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0508 0.1771
Schistosoma mansoni DNA topoisomerase II 0.0065 0.0532 0.0532
Onchocerca volvulus 0.0025 0.0075 0.0139
Loa Loa (eye worm) hypothetical protein 0.0149 0.1508 0.2394
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.042 0.042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.151 0.2396
Plasmodium vivax amine transporter, putative 0.0029 0.0116 0.2177
Echinococcus granulosus Nuclear hormone receptor HR96 0.0081 0.0725 0.0725
Brugia malayi EGF-like domain containing protein 0.0023 0.0055 0.0087
Echinococcus granulosus slit 2 protein 0.0023 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0146 0.1473 0.8402
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0029 0.0116 0.0116
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0029 0.0116 0.0116
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0021 0.0027 0.0042
Leishmania major cytochrome p450-like protein 0.0035 0.019 0.0976
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0812 0.1288
Brugia malayi nuclear receptor RXR 0.0099 0.0928 0.1473
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.018 0.1869 0.2967
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0184
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.2718
Schistosoma mansoni sodium/chloride dependent transporter 0.0169 0.1741 0.1741
Trypanosoma brucei lanosterol synthase 0.0153 0.1559 0.8901
Brugia malayi hypothetical protein 0.0099 0.0928 0.1473
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0006 0.0009
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0006 0.0006

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) < 15 % Inhibition of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid uptake at 5 mM after 60 secs relative to L-citrulline ChEMBL. 19060912
Log 1/T (functional) = 1.49 Bitter threshold value ChEMBL. 3656360
Log 1/T (functional) = 1.49 Bitter tasting threshold of the compound was expressed as log 1/T. ChEMBL. 7629809
logP (ADMET) = 3.18 Partition coefficient (logP) ChEMBL. 3656360

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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