Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0023 | 0.0075 | 0.0075 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0022 | 0 | 0.5 |
Echinococcus granulosus | slit 2 protein | 0.0023 | 0.0075 | 0.0075 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.7435 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Echinococcus granulosus | pikachurin | 0.0023 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.7435 | 1 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0023 | 0.0075 | 0.0101 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus multilocularis | pikachurin | 0.0023 | 0.0075 | 0.0075 |
Brugia malayi | EGF-like domain containing protein | 0.0023 | 0.0075 | 0.0101 |
Brugia malayi | laminin alpha chain | 0.0023 | 0.0075 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0131 | 0.7435 | 0.7435 |
Echinococcus multilocularis | geminin | 0.0169 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus multilocularis | slit 2 protein | 0.0023 | 0.0075 | 0.0075 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0022 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0075 | 0.0101 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0131 | 0.7435 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0131 | 0.7435 | 0.7435 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 0.7435 | 1 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0023 | 0.0075 | 0.0075 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0131 | 0.7435 | 0.7435 |
Loa Loa (eye worm) | carboxylesterase | 0.0131 | 0.7435 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0131 | 0.7435 | 0.7435 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0022 | 0 | 0.5 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0023 | 0.0075 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0075 | 0.0101 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0131 | 0.7435 | 0.7435 |
Schistosoma mansoni | slit | 0.0023 | 0.0075 | 0.0075 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0022 | 0 | 0.5 |
Schistosoma mansoni | cell polarity protein | 0.0023 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.7435 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0023 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0075 | 0.0101 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0023 | 0.0075 | 0.0075 |
Brugia malayi | laminin-like protein K08C7.3 precursor | 0.0023 | 0.0075 | 0.0101 |
Echinococcus granulosus | carboxylesterase 5A | 0.0131 | 0.7435 | 0.7435 |
Echinococcus granulosus | acetylcholinesterase | 0.0131 | 0.7435 | 0.7435 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.