Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1804 | 0.1039 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0225 | 0.2574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0225 | 0.2574 | 1 |
Brugia malayi | Peptidase family M13 containing protein | 0.0186 | 0.1804 | 0.1645 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0225 | 0.2574 | 0.1881 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0186 | 0.1804 | 0.1645 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0186 | 0.1804 | 0.701 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1804 | 0.1039 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0186 | 0.1804 | 0.5 |
Toxoplasma gondii | peptidase family M13 protein | 0.0186 | 0.1804 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0225 | 0.2574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1804 | 0.1039 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0186 | 0.1804 | 0.5 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0186 | 0.1804 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0917 | 0.0069 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.