Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | SHC transforming protein 3 | 0.0037 | 0.1784 | 0.1784 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0142 | 0.9977 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Entamoeba histolytica | protein kinase, putative | 0.0068 | 0.4195 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0074 | 0.4638 | 0.4637 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.0037 | 0.1784 | 0.1788 |
Schistosoma mansoni | GTPase activating protein | 0.0037 | 0.1784 | 0.177 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0036 | 0.1711 | 0.1697 |
Brugia malayi | SH2 domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Schistosoma mansoni | dreadlocks/dock | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0142 | 0.9977 | 0.9977 |
Schistosoma mansoni | sorbin | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | TK protein kinase | 0.0105 | 0.7122 | 0.7132 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2B | 0.0015 | 0.0023 | 0.5 |
Brugia malayi | Tensin | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | p53BP2 | 0.0036 | 0.1711 | 0.1697 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.1616 | 0.139 |
Brugia malayi | protein-tyrosine kinase | 0.0036 | 0.1711 | 0.1697 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | tyrosine kinase | 0.0142 | 0.9977 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.2549 | 1 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0105 | 0.7122 | 0.7122 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.2549 | 0.6055 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.4047 |
Entamoeba histolytica | protein kinase, putative | 0.0036 | 0.1711 | 0.4047 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0084 | 0.546 | 0.5473 |
Schistosoma mansoni | slit-robo rho gtpase activating protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Trypanosoma cruzi | paraflagellar rod protein 5, putative | 0.0036 | 0.1711 | 0.5 |
Brugia malayi | Myosin tail family protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.2549 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0048 | 0.2606 | 0.6191 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0074 | 0.4638 | 0.4637 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0074 | 0.4638 | 0.4637 |
Brugia malayi | SRC-1 | 0.0142 | 0.9977 | 1 |
Brugia malayi | Peripheral plasma membrane protein CASK | 0.0036 | 0.1711 | 0.1697 |
Trichomonas vaginalis | p67phox protein, putative | 0.0036 | 0.1711 | 1 |
Schistosoma mansoni | tensin | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | cell polarity protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0142 | 0.9977 | 1 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK3 | 0.0015 | 0.0023 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1616 | 0.1601 |
Echinococcus multilocularis | SH2 motif | 0.0037 | 0.1784 | 0.1788 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | hypothetical protein | 0.0037 | 0.1784 | 0.1784 |
Echinococcus multilocularis | N chimaerin | 0.0037 | 0.1784 | 0.1788 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0037 | 0.1784 | 0.1784 |
Echinococcus granulosus | hematopoietic lineage cell specific protein | 0.0036 | 0.1711 | 0.1711 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.0037 | 0.1784 | 0.1788 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.0037 | 0.1784 | 0.1784 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.2549 | 0.2538 |
Echinococcus granulosus | slit robo rho gtpase activating protein 1 | 0.0036 | 0.1711 | 0.1711 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.2549 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.2549 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | expressed protein | 0.0036 | 0.1711 | 0.1711 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0048 | 0.2606 | 0.2606 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.2549 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Brugia malayi | Variant SH3 domain containing protein | 0.0074 | 0.4638 | 0.4637 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0068 | 0.4195 | 0.4195 |
Echinococcus granulosus | Spectrin alpha actinin | 0.0036 | 0.1712 | 0.1712 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.2549 | 0.6055 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0105 | 0.7122 | 0.7139 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine kinase | 0.0048 | 0.2606 | 0.2606 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.4638 | 0.4637 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0037 | 0.1784 | 0.1784 |
Onchocerca volvulus | 0.0037 | 0.1735 | 0.0262 | |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | epidermal growth factor receptor kinase | 0.0036 | 0.1711 | 0.1715 |
Echinococcus multilocularis | nostrin | 0.0036 | 0.1711 | 0.1715 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type 1 | 0.0015 | 0.0023 | 0.0023 |
Echinococcus multilocularis | breast cancer anti estrogen resistance protein | 0.0036 | 0.1711 | 0.1715 |
Echinococcus granulosus | c src tyrosine kinase | 0.0084 | 0.546 | 0.546 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.0037 | 0.1784 | 0.1784 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2A | 0.0015 | 0.0023 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Brugia malayi | RhoGAP domain containing protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 1 |
Schistosoma mansoni | tensin | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0074 | 0.4638 | 0.4637 |
Loa Loa (eye worm) | SRC-1 | 0.0142 | 0.9977 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 1 |
Schistosoma mansoni | shc transforming protein | 0.0037 | 0.1784 | 0.177 |
Onchocerca volvulus | Suppressor of cytokine signaling 7 homolog | 0.0037 | 0.1784 | 0.0812 |
Entamoeba histolytica | SH2 domain containing protein | 0.0037 | 0.1784 | 0.4221 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0048 | 0.2606 | 0.2606 |
Brugia malayi | Spectrin alpha chain | 0.0036 | 0.1712 | 0.1697 |
Echinococcus granulosus | endophilin A3 | 0.0036 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0142 | 0.9977 | 0.9977 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0074 | 0.4638 | 0.4638 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.5 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0037 | 0.1784 | 0.1788 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0068 | 0.4195 | 0.4205 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.2549 | 1 |
Brugia malayi | Fes/CIP4 homology domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.2549 | 0.2538 |
Echinococcus granulosus | nostrin | 0.0036 | 0.1711 | 0.1711 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.1616 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Entamoeba histolytica | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.4047 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1616 | 0.1601 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | 0.0037 | 0.1784 | 0.1788 | |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.2549 | 1 |
Schistosoma mansoni | sorting nexin | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | arf GAP with SH3 domain, ANK repeat and PH | 0.0036 | 0.1711 | 0.1715 |
Echinococcus granulosus | expressed conserved protein | 0.0037 | 0.1784 | 0.1784 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.6684 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Loa Loa (eye worm) | STAT protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1712 | 0.1697 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0084 | 0.546 | 0.5463 |
Echinococcus granulosus | N chimaerin | 0.0037 | 0.1784 | 0.1784 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | rho guanine nucleotide exchange factor 7 | 0.0036 | 0.1711 | 0.1715 |
Loa Loa (eye worm) | protein-tyrosine kinase | 0.0036 | 0.1711 | 0.1697 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.1616 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.2549 | 0.6055 |
Schistosoma mansoni | run and tbc1 domain containing | 0.0036 | 0.1711 | 0.1697 |
Brugia malayi | Variant SH3 domain containing protein | 0.0074 | 0.4638 | 0.4637 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.2549 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Brugia malayi | Src substrate cortactin | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0084 | 0.546 | 0.5473 |
Entamoeba histolytica | protein kinase, putative | 0.0038 | 0.1808 | 0.4278 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 0.9977 |
Echinococcus granulosus | tyrosine kinase | 0.0105 | 0.7122 | 0.7122 |
Schistosoma mansoni | sh3-containing grb2-like protein 1 (endophilin II) | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | TK protein kinase | 0.0068 | 0.4195 | 0.4192 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0037 | 0.1784 | 0.1788 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0074 | 0.4638 | 0.4637 |
Entamoeba histolytica | BAR/SH3 domain containing protein | 0.0036 | 0.1711 | 0.4047 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1616 | 0.1601 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.2549 | 0.2538 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.0037 | 0.1784 | 0.1784 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 0.9977 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | tensin | 0.0037 | 0.1784 | 0.1788 |
Schistosoma mansoni | signal transducing adapter molecule (stam) | 0.0036 | 0.1711 | 0.1697 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0048 | 0.2606 | 0.2595 |
Brugia malayi | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Brugia malayi | protein-tyrosine kinase | 0.0105 | 0.7122 | 0.7132 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0037 | 0.1784 | 0.177 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.2549 | 1 |
Schistosoma mansoni | adapter molecule crk | 0.0074 | 0.4638 | 0.4637 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Brugia malayi | SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | SH2 motif | 0.0037 | 0.1784 | 0.1784 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0074 | 0.4638 | 0.4637 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.0037 | 0.1784 | 0.1788 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Brugia malayi | Guanylate kinase family protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1616 | 0.1601 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.0037 | 0.1784 | 0.1784 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0142 | 0.9977 | 1 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2606 | 0.2595 |
Echinococcus multilocularis | SH2 motif | 0.0037 | 0.1784 | 0.1788 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0048 | 0.2606 | 0.2606 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Echinococcus multilocularis | NCK adaptor protein | 0.0074 | 0.4638 | 0.4649 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0142 | 0.9977 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | Dab2-interacting protein-like | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0048 | 0.2606 | 0.2612 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1711 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor kinase | 0.0036 | 0.1711 | 0.1711 |
Echinococcus granulosus | NCK adaptor protein | 0.0074 | 0.4638 | 0.4638 |
Loa Loa (eye worm) | guanylate kinase | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0095 | 0.63 | 0.6315 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0038 | 0.1808 | 0.4278 |
Echinococcus multilocularis | transfer RNA-Ala | 0.0036 | 0.1711 | 0.1715 |
Echinococcus multilocularis | tensin | 0.0037 | 0.1784 | 0.1788 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.0037 | 0.1784 | 0.1788 |
Echinococcus granulosus | intersectin 2 | 0.0036 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | slit robo rho gtpase activating protein 1 | 0.0036 | 0.1711 | 0.1715 |
Brugia malayi | hypothetical protein | 0.0048 | 0.2606 | 0.2595 |
Echinococcus granulosus | rho guanine nucleotide exchange factor 7 | 0.0036 | 0.1711 | 0.1711 |
Echinococcus granulosus | tensin | 0.0037 | 0.1784 | 0.1784 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0084 | 0.546 | 0.546 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0037 | 0.1784 | 0.1788 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0074 | 0.4638 | 0.4649 |
Echinococcus multilocularis | expressed protein | 0.0036 | 0.1711 | 0.1715 |
Echinococcus multilocularis | hematopoietic lineage cell specific protein | 0.0036 | 0.1711 | 0.1715 |
Schistosoma mansoni | tensin | 0.0037 | 0.1784 | 0.177 |
Onchocerca volvulus | 0.0037 | 0.1784 | 0.0812 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.2549 | 0.2538 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0048 | 0.2606 | 0.2612 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.1616 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 0.9977 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0105 | 0.7122 | 0.7139 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0105 | 0.7122 | 0.7139 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0037 | 0.1784 | 0.177 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0037 | 0.1784 | 0.1788 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0037 | 0.1784 | 0.177 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0142 | 0.9977 | 1 |
Schistosoma mansoni | tensin-related | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | nck2/grb4 | 0.0074 | 0.4638 | 0.4637 |
Schistosoma mansoni | tyrosine kinase | 0.0142 | 0.9977 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Schistosoma mansoni | C-fyn | 0.0036 | 0.1711 | 0.1697 |
Brugia malayi | Variant SH3 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Trichomonas vaginalis | neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative | 0.0036 | 0.1711 | 1 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0048 | 0.2606 | 0.2612 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.2549 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.2549 | 0.2538 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | Spectrin alpha actinin | 0.0036 | 0.1712 | 0.1716 |
Onchocerca volvulus | Suppressor of cytokine signaling at 36E homolog | 0.0037 | 0.1784 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0048 | 0.2606 | 0.2606 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1616 | 0.1601 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0084 | 0.546 | 0.5463 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | tyrosine kinase | 0.0084 | 0.546 | 0.5463 |
Schistosoma mansoni | development and differentiation-enhancing factor ddef | 0.0036 | 0.1711 | 0.1697 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.2549 | 0.2538 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0095 | 0.63 | 0.63 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.0047 | 0.2549 | 0.9368 | |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | src region | 0.0036 | 0.1711 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.2606 | 0.2595 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0048 | 0.2606 | 0.2595 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.0037 | 0.1784 | 0.1784 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.1711 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0037 | 0.1784 | 0.1784 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.0037 | 0.1784 | 0.1788 |
Schistosoma mansoni | SH2A | 0.0037 | 0.1784 | 0.177 |
Onchocerca volvulus | 0.0048 | 0.2606 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0142 | 0.9977 | 1 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0037 | 0.1784 | 0.1788 |
Schistosoma mansoni | formin binding protein and related proteins | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine kinase | 0.0048 | 0.2606 | 0.2612 |
Echinococcus granulosus | SH2 motif | 0.0037 | 0.1784 | 0.1784 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0105 | 0.7122 | 0.7122 |
Brugia malayi | Variant SH3 domain containing protein | 0.0036 | 0.1711 | 0.1697 |
Loa Loa (eye worm) | protein kinase C and casein kinase substrate in neurons protein 2 | 0.0036 | 0.1711 | 0.1697 |
Schistosoma mansoni | dynamin-associated protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0037 | 0.1784 | 0.1784 |
Schistosoma mansoni | vav2 | 0.0037 | 0.1784 | 0.177 |
Schistosoma mansoni | tyrosine kinase | 0.0084 | 0.546 | 0.5463 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0047 | 0.2533 | 0.2522 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Echinococcus multilocularis | SH2 motif | 0.0037 | 0.1784 | 0.1788 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.2549 | 0.5 |
Echinococcus multilocularis | intersectin 2 | 0.0036 | 0.1711 | 0.1715 |
Schistosoma mansoni | tyrosine kinase | 0.0048 | 0.2606 | 0.2595 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0048 | 0.2606 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1784 | 0.177 |
Entamoeba histolytica | unconventional myosin IB | 0.0036 | 0.1711 | 0.4047 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0142 | 0.9977 | 0.9977 |
Schistosoma mansoni | tensin-related | 0.0037 | 0.1784 | 0.177 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.2549 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.2549 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0037 | 0.1784 | 0.177 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0084 | 0.546 | 0.5473 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0015 | 0.0023 | 0.0023 |
Echinococcus granulosus | fch and double sh3 domains protein 2 | 0.0036 | 0.1711 | 0.1711 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.0037 | 0.1784 | 0.1784 |
Schistosoma mansoni | eps8-related protein | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0037 | 0.1784 | 0.1788 |
Schistosoma mansoni | apoptosis stimulating of P53 | 0.0036 | 0.1711 | 0.1697 |
Entamoeba histolytica | BAR/SH3 domain containing protein | 0.0036 | 0.1711 | 0.4047 |
Brugia malayi | Variant SH3 domain containing protein | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | breast cancer anti estrogen resistance protein | 0.0036 | 0.1711 | 0.1711 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.2549 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1711 | 0.4047 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.0037 | 0.1784 | 0.177 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0142 | 0.9977 | 0.9977 |
Loa Loa (eye worm) | thyroid receptor interactor | 0.0036 | 0.1711 | 0.1697 |
Echinococcus multilocularis | fch and double sh3 domains protein 2 | 0.0036 | 0.1711 | 0.1715 |
Echinococcus multilocularis | endophilin A3 | 0.0036 | 0.1711 | 0.1715 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.2549 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0142 | 0.9977 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0037 | 0.1784 | 0.177 |
Trypanosoma brucei | conserved protein | 0.0036 | 0.1711 | 1 |
Echinococcus granulosus | arf GAP with SH3 domain ANK repeat and PH | 0.0036 | 0.1711 | 0.1711 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 300 uM | Inhibitory activity against accumulation of [14C]-labeled linezolid within wildtype E. coli K12 cells | ChEMBL. | 11459657 |
IC50 (functional) | = 300 uM | Inhibitory activity against accumulation of [14C]-labeled linezolid within wildtype E. coli K12 cells | ChEMBL. | 11459657 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against S. aureus strain ATCC 29213 | ChEMBL. | 11459657 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against E. coli strain ATCC 25922 | ChEMBL. | 11459657 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against E. coli strain ATCC 25922 | ChEMBL. | 11459657 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.