Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypoxia-induced factor 1 | 0.0159 | 0.2751 | 0.2751 |
Echinococcus multilocularis | geminin | 0.0179 | 0.3992 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0115 | 0 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0131 | 0.1008 | 0.2524 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.3992 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0159 | 0.2751 | 0.2992 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0115 | 0 | 0.5 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.9098 | 0.9895 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.3581 | 0.3895 |
Echinococcus granulosus | geminin | 0.0179 | 0.3992 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0263 | 0.9195 | 0.9195 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.2714 | 0.68 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0159 | 0.2714 | 0.68 |
Schistosoma mansoni | hypothetical protein | 0.0131 | 0.1008 | 0.2524 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0263 | 0.9195 | 1 |
Brugia malayi | hypothetical protein | 0.0172 | 0.3581 | 0.3581 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0263 | 0.9195 | 0.9195 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0115 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.2714 | 0.68 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0131 | 0.1008 | 0.2524 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.3992 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0115 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.