Detailed information for compound 83605

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.395 | Formula: C24H17NO5
  • H donors: 1 H acceptors: 3 LogP: 4.29 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1c(c2ccc3c(c2)OCO3)c2ccccc2n(c1=O)Cc1ccccc1
  • InChi: 1S/C24H17NO5/c26-23-22(24(27)28)21(16-10-11-19-20(12-16)30-14-29-19)17-8-4-5-9-18(17)25(23)13-15-6-2-1-3-7-15/h1-12H,13-14H2,(H,27,28)
  • InChiKey: IHOHLVAWAOKHJX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Endothelin receptor ET-A Starlite/ChEMBL No references
Homo sapiens endothelin receptor type B Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 21.1 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 20.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0305 0.0729
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0019 0.0027
Echinococcus granulosus voltage dependent calcium channel 0.0077 0.0743 0.0744
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0076
Toxoplasma gondii phospholipase 0.0026 0.0144 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.02 0.2179 0.4296
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0022 0.0022
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0305 0.0305
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0829
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Onchocerca volvulus 0.0044 0.0358 0.1266
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0038 0.0038
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.004 0.004
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0004 0.0004
Brugia malayi hypothetical protein 0.0044 0.0358 0.0698
Onchocerca volvulus 0.0039 0.0293 0.1036
Echinococcus granulosus flap endonuclease 1 0.0028 0.0168 0.0168
Plasmodium falciparum metacaspase 1 0.0047 0.0396 0.0744
Echinococcus granulosus carboxylesterase 5A 0.0145 0.154 0.1544
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0114
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.003 0.0073
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.004 0.0068
Trichomonas vaginalis DNA polymerase eta, putative 0.0108 0.1101 0.2632
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0139 0.0264
Brugia malayi Carboxylesterase family protein 0.0025 0.0129 0.0246
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0019 0.0027
Trypanosoma cruzi heat shock protein 90, putative 0.0015 0.002 0.004
Schistosoma mansoni glutamate synthase 0.0053 0.0462 0.046
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0063 0.0578 0.1134
Echinococcus multilocularis serotonin receptor 0.0046 0.0375 0.0375
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0144 0.0245
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.3503 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0034 0.0035
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0147 0.1559 0.3068
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.002 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0419 0.082
Echinococcus granulosus voltage dependent calcium channel 0.0131 0.1371 0.1375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0221 0.0398
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0462 0.0904
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.0442 0.0865
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0015 0.002 0.0003
Schistosoma mansoni hypothetical protein 0.0866 0.9976 1
Mycobacterium ulcerans hypothetical protein 0.0016 0.0028 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0139 0.0266
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0004 0.0007
Echinococcus multilocularis thyroid hormone receptor alpha 0.0167 0.1799 0.1799
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0028 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0254 0.0607
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0019 0.0027
Schistosoma mansoni ap endonuclease 0.004 0.0308 0.0305
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0076
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0157 0.0303
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0578 0.058
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Schistosoma mansoni pyruvate dehydrogenase 0.0015 0.002 0.0016
Plasmodium falciparum ferrodoxin reductase-like protein 0.0053 0.0462 0.0875
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.1093 0.308
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0175 0.1888 0.5593
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0305 0.0305
Echinococcus granulosus muscleblind protein 0.016 0.1713 0.1717
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0053 0.0462 0.0904
Brugia malayi kinase, mitochondrial precursor 0.0015 0.002 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0167 0.1799 0.18
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0221 0.0429
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0375 0.0376
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0107 0.0107
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0139 0.0358
Loa Loa (eye worm) carboxylesterase 0.0145 0.154 0.2769
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0144 0.0344
Echinococcus granulosus BC026374 protein S09 family 0.0025 0.0129 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0129 0.0231
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0259
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.002 0.004
Schistosoma mansoni thyroid hormone receptor 0.0167 0.1799 0.18
Loa Loa (eye worm) hypothetical protein 0.034 0.3816 0.686
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.048 0.0946
Plasmodium falciparum BEM46-like protein, putative 0.0026 0.0144 0.0245
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0375 0.0376
Toxoplasma gondii transporter, cation channel family protein 0.0077 0.0743 0.1458
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0053 0.0462 0.0902
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.1319 0.1319
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0168 0.0302
Onchocerca volvulus 0.0046 0.0375 0.1328
Brugia malayi Cytochrome P450 family protein 0.0036 0.0258 0.0502
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Giardia lamblia GTOR 0.0048 0.0405 0.1104
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0609 0.0607
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0053 0.0462 0.1269
Echinococcus granulosus TRP transient receptor potential channel 0.0014 0.0004 0.0004
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0053 0.0462 0.0902
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0254 0.0501
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0015 0.002 0.003
Leishmania major DNA polymerase eta, putative 0.0051 0.0442 0.0871
Brugia malayi MGC79044 protein 0.0026 0.0144 0.0277
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Echinococcus granulosus hypothetical protein 0.0046 0.0375 0.0376
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0032 0.0032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0375 0.0376
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0022 0.0035
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0021 0.0037
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0375 0.0733
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0016 0.0034 0.0061
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0273 0.0653
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0107 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.048 0.1147
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0231 0.0228
Leishmania major hypothetical protein, conserved 0.0053 0.0462 0.0911
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.004 0.0078
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0147 0.1559 0.3068
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0171 0.1839 0.5223
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.009 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0308 0.0606
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0139 0.0358
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Brugia malayi Cytochrome P450 family protein 0.0015 0.0019 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0304 0.0728
Echinococcus granulosus sex peptide receptor 0.0046 0.0375 0.0376
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0376 0.0898
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Onchocerca volvulus 0.0046 0.0375 0.1328
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0831
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0016 0.0034 0.0034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0375 0.0375
Echinococcus multilocularis voltage dependent calcium channel 0.0131 0.1371 0.1371
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0553 0.0995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0145 0.0347
Onchocerca volvulus 0.0046 0.0375 0.1328
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0304 0.0854
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0139 0.0399
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0051 0.0091
Echinococcus multilocularis tumor protein p63 0.0362 0.4075 0.4075
Schistosoma mansoni glutamate synthase 0.0053 0.0462 0.046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0375 0.0373
Schistosoma mansoni DNA topoisomerase II 0.0293 0.3268 0.3273
Echinococcus granulosus hypothetical protein 0.0014 0.0004 0.0004
Chlamydia trachomatis thioredoxin reductase 0.0053 0.0462 0.2023
Schistosoma mansoni hypothetical protein 0.0046 0.0375 0.0373
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0114
Leishmania major hypothetical protein, conserved 0.0017 0.0038 0.0075
Brugia malayi Cytochrome P450 family protein 0.0025 0.0129 0.0247
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.1419 0.1422
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0021 0.0037
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0447 0.5072 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0273 0.0653
Schistosoma mansoni hypothetical protein 0.0346 0.3897 0.3904
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0375 0.0376
Echinococcus granulosus caspase 2 0.0091 0.0912 0.0914
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Schistosoma mansoni neuropeptide receptor 0.0046 0.0375 0.0373
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0125 0.1307 0.1307
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0375 0.0375
Loa Loa (eye worm) voltage-dependent calcium channel 0.0077 0.0743 0.1335
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0089 0.0089
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.1093 0.2155
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.3503 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0089 0.0159
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0254 0.0607
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0375 0.0373
Toxoplasma gondii NADPH-glutathione reductase 0.02 0.2179 0.4292
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0375 0.0376
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0157 0.031
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0026 0.0144 0.0277
Brugia malayi Cell death protein 3 precursor 0.0091 0.0912 0.1792
Schistosoma mansoni transient receptor potential channel 0.0014 0.0005 0.0002
Brugia malayi jmjC domain containing protein 0.0017 0.0038 0.0068
Plasmodium falciparum exported lipase 2 0.0026 0.0144 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.003 0.0073
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.048 0.094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0076
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0405 0.1104
Brugia malayi heat shock protein 90 0.0015 0.002 0.0032
Echinococcus multilocularis dna polymerase kappa 0.0108 0.1101 0.1101
Leishmania major metacaspase, putative 0.0047 0.0396 0.078
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0254 0.0607
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0051 0.0443 0.0874
Loa Loa (eye worm) glutathione reductase 0.0447 0.5072 0.9119
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0703 0.0704
Brugia malayi nuclear receptor NHR-67 0.0015 0.0021 0.0034
Echinococcus multilocularis BC026374 protein (S09 family) 0.0025 0.0129 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0687 0.1348
Mycobacterium ulcerans DNA topoisomerase I 0.0016 0.0026 0.0022
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.02 0.2179 0.429
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0016 0.0026 0.0048
Trichomonas vaginalis heat shock protein, putative 0.0015 0.002 0.0048
Onchocerca volvulus 0.0255 0.2826 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0619 0.0617
Trichomonas vaginalis glutathione reductase, putative 0.02 0.2179 0.5209
Echinococcus multilocularis cpg binding protein 0.0064 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0131 0.1371 0.2466
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0254 0.0607
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0053 0.0462 0.1325
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0071 0.067 0.1949
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0168 0.0401
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Leishmania major acetoin dehydrogenase e3 component-like protein 0.02 0.2179 0.4296
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0051 0.0435 0.0435
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0065 0.0061
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0129 0.0254
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0375 0.0375
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like protein, putative 0.0017 0.0046 0.0084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Brugia malayi intermediate filament protein 0.0029 0.0179 0.0347
Schistosoma mansoni hypothetical protein 0.0053 0.0462 0.046
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0602 0.06
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0063 0.0578 0.2586
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0019 0.0037
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0046 0.0091
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0375 0.0375
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0375 0.0373
Brugia malayi hypothetical protein 0.0021 0.0089 0.0167
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Trypanosoma cruzi serine peptidase, putative 0.0026 0.0144 0.0284
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0016 0.0026 0.0063
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.004 0.004
Echinococcus granulosus shaker cognate 0.0014 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0308 0.0735
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus transient receptor potential gamma protein 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0019 0.0027
Trypanosoma brucei monoglyceride lipase, putative 0.0301 0.3362 0.6626
Loa Loa (eye worm) DR-78 0.0015 0.0021 0.0037
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0375 0.0375
Brugia malayi Uncoordinated protein 44 0.0015 0.0022 0.0035
Brugia malayi hypothetical protein 0.0017 0.0042 0.0076
Echinococcus granulosus glutamate synthase 0.0053 0.0462 0.0463
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0021 0.0074
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0144 0.0344
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0293 0.057
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0164 0.1759 0.3461
Onchocerca volvulus 0.0046 0.0375 0.1328
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0038 0.0038
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0305 0.0302
Echinococcus granulosus heat shock protein 90 0.0015 0.002 0.002
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0065 0.0605 0.1185
Onchocerca volvulus 0.0097 0.0978 0.3459
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0179 0.0323
Loa Loa (eye worm) RecQ helicase 0.0021 0.009 0.0162
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0221 0.0429
Echinococcus granulosus intermediate filament protein 0.0029 0.0179 0.018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium ulcerans flavoprotein disulfide reductase 0.02 0.2179 0.6462
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.002 0.0048
Echinococcus granulosus lamin dm0 0.0029 0.0179 0.018
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0005 0.0005
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0802 0.1442
Brugia malayi glutamate synthase 0.0053 0.0462 0.0904
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0374 0.0737
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0305 0.0601
Loa Loa (eye worm) hypothetical protein 0.0072 0.0687 0.1235
Schistosoma mansoni flap endonuclease-1 0.0025 0.0137 0.0133
Leishmania major DNA polymerase kappa, putative 0.0065 0.0605 0.1194
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0016 0.0034 0.0034
Brugia malayi neuropeptide F receptor 0.0046 0.0375 0.0733
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.0375 0.1328
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0308 0.0825
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0221 0.0218
Echinococcus granulosus neuropeptide receptor 0.0046 0.0375 0.0376
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0171 0.1839 0.8427
Trypanosoma cruzi metacaspase, putative 0.0047 0.0396 0.078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0376 0.0898
Schistosoma mansoni opsin-like receptor 0.0046 0.0375 0.0373
Treponema pallidum hypothetical protein 0.005 0.0423 0.1156
Trypanosoma cruzi metacaspase, putative 0.0047 0.0396 0.078
Schistosoma mansoni amine GPCR 0.0577 0.66 0.6614
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0168 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0139 0.0266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0221 0.0398
Brugia malayi Pre-SET motif family protein 0.0224 0.2464 0.4855
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Schistosoma mansoni amine GPCR 0.0046 0.0375 0.0373
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0308 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0375 0.0675
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0375 0.0375
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.02 0.2179 0.6462
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0396 0.078
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0053 0.0462 0.0463
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0375 0.0376
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0371 0.4183 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.0442 0.0862
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0065 0.0065
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0065 0.0065
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0107 0.0107
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0308 0.0863
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0619 0.1113
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0609 0.0609
Loa Loa (eye worm) calcium channel 0.0131 0.1371 0.2466
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0461 0.0459
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0442 0.0871
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0221 0.0429
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0053 0.0462 0.1105
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0405 0.0798
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0175 0.1888 0.5593
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0026 0.0144 0.0284
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0375 0.0733
Toxoplasma gondii heat shock protein HSP90 0.0015 0.002 0.0032
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0077 0.0743 0.1458
Giardia lamblia DINP protein human, muc B family 0.0065 0.0605 0.1681
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0028 0.0055
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0015 0.002 0.003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.048 0.094
Trypanosoma brucei metacaspase MCA2 0.0047 0.0396 0.0773
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0005 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0022 0.0039
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0071 0.067 0.1949
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0053 0.0462 0.1105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Trypanosoma brucei protein kinase, putative 0.0055 0.048 0.094
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.02 0.2179 0.4292
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0053 0.0462 0.0911
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0254 0.0607
Leishmania major DNA topoisomerase III, putative 0.0016 0.0026 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0289 0.0692
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.1728 0.3106
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0293 0.3268 0.3268
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0175 0.1888 0.3717
Loa Loa (eye worm) endoplasmin 0.0015 0.002 0.0036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0304 0.0728
Onchocerca volvulus 0.0046 0.0375 0.1328
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0221 0.0218
Entamoeba histolytica disulphide oxidoreductase, putative 0.0053 0.0462 0.1269
Echinococcus granulosus neuroligin 0.0025 0.0129 0.0129
Onchocerca volvulus 0.0015 0.0021 0.0074
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0053 0.0462 0.0902
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.009 0.017
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0053 0.0462 0.0904
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0029 0.0178 0.0706
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0053 0.0462 0.0902
Schistosoma mansoni neuroligin 3 (S09 family) 0.0025 0.0129 0.0125
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0065 0.0065
Schistosoma mansoni peptidase 0.0026 0.0144 0.0141
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0073 0.0136
Echinococcus multilocularis shaker cognate 0.0014 0.0004 0.0004
Brugia malayi hypothetical protein 0.0017 0.0042 0.0076
Brugia malayi RE15519p 0.0046 0.0375 0.0733
Mycobacterium ulcerans hypothetical protein 0.0026 0.0144 0.0374
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0076 0.0732 0.2106
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0053 0.0462 0.0904
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0004 0.0004
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0144 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0019 0.0027
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0305 0.0594
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0489 0.5562 1
Toxoplasma gondii thioredoxin reductase 0.0447 0.5072 1
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0053 0.0462 0.1325
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0405 0.1104
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Onchocerca volvulus 0.0016 0.0026 0.0091
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.0375 0.1328
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0008
Echinococcus granulosus tumor protein p63 0.0362 0.4075 0.4084
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0064 0.0086
Giardia lamblia NADH oxidase lateral transfer candidate 0.02 0.2179 0.6198
Schistosoma mansoni biogenic amine receptor 0.0046 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0053 0.0462 0.0875
Loa Loa (eye worm) hypothetical protein 0.0025 0.0139 0.0249
Mycobacterium ulcerans lysophospholipase 0.0301 0.3362 1
Schistosoma mansoni nuclear receptor 0.0015 0.0021 0.0017
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0442 0.0795
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.009 0.0177
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0053 0.0462 0.1105
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1699 0.1699
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0004 0.0004
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0016 0.0034 0.0034
Brugia malayi DNA topoisomerase III beta-1 0.0016 0.0026 0.0045
Trypanosoma brucei DNA topoisomerase III, putative 0.0016 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0046 0.0374 0.0673
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0602 0.1179
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0405 0.0405
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0375 0.0733
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Loa Loa (eye worm) hypothetical protein 0.0091 0.0912 0.1639
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Loa Loa (eye worm) carboxylesterase 0.0025 0.0129 0.0231
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0003 0.0007
Echinococcus granulosus abhydrolase domain containing protein 13 0.0026 0.0144 0.0144
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0053 0.0462 0.0904
Plasmodium falciparum DNA topoisomerase 2 0.0293 0.3268 0.6428
Brugia malayi ecdysone receptor 0.0015 0.0021 0.0034
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0026 0.0052
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0038 0.0034
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0168 0.0331
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Trichomonas vaginalis glutamate synthase, putative 0.0053 0.0462 0.1105
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.004 0.0078
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0254 0.0501
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0254 0.0493
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0026 0.0144 0.0284
Entamoeba histolytica hypothetical protein 0.0026 0.0144 0.0356
Trichomonas vaginalis endoplasmin, putative 0.0015 0.002 0.0048
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0139 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.02 0.2179 1
Onchocerca volvulus 0.0025 0.0129 0.0455
Schistosoma mansoni lipoxygenase 0.0088 0.0875 0.0873
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0221 0.0218
Schistosoma mansoni lamin 0.0029 0.0179 0.0176
Onchocerca volvulus Cell death protein 3 homolog 0.0091 0.0912 0.3227
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0021 0.0034
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0129 0.0125
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0015 0.002 0.003
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0004 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.1248 0.2455
Plasmodium vivax glutathione reductase, putative 0.0447 0.5072 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Plasmodium falciparum esterase, putative 0.0301 0.3362 0.6615
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0022 0.0018
Leishmania major hypothetical protein, conserved 0.0015 0.002 0.004
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0053 0.0462 0.1329
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0065 0.0061
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0019 0.0055
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0079 0.0079
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Mycobacterium ulcerans hypothetical protein 0.017 0.1834 0.5431
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0144 0.0284
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0802 0.2307
Schistosoma mansoni hypothetical protein 0.0141 0.1492 0.1493
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0375 0.0375
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0065 0.0061
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.009 0.017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0053 0.0462 0.1329
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0094 0.0225
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0015 0.002 0.0003
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0015 0.002 0.0003
Leishmania major DNA topoisomerase 1A 0.0016 0.0026 0.0052
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0308 0.1332
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0301 0.3362 0.9594
Schistosoma mansoni myosin xvIII 0.0046 0.0375 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0065 0.0065
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Plasmodium vivax PST-A protein 0.0026 0.0144 0.0245
Echinococcus multilocularis abhydrolase domain containing 3 0.0026 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0145 0.154 0.2769
Loa Loa (eye worm) hypothetical protein 0.0015 0.002 0.0036
Mycobacterium ulcerans carboxylesterase, LipT 0.0025 0.0129 0.0328
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0053 0.0462 0.1329
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0004 0.0004
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0026 0.0144 0.0144
Echinococcus granulosus fmrfamide receptor 0.0046 0.0375 0.0376
Plasmodium falciparum prodrug activation and resistance esterase 0.0026 0.0144 0.0245
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0375 0.0376
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.004 0.004
Trypanosoma brucei DNA polymerase eta, putative 0.0051 0.0442 0.0865
Echinococcus multilocularis glutamate synthase 0.0053 0.0462 0.0462
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.2464 0.4431
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0004 0.0004
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0015 0.002 0.003
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0221 0.0218
Echinococcus granulosus Ankyrin 0.0016 0.0023 0.0023
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0021 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.1834 0.3611
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0139 0.034
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.011 0.1128 0.3319
Brugia malayi Thioredoxin reductase 0.0447 0.5072 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0396 0.0773
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0602 0.1187
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.002 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0375 0.0375
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0129 0.0125
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0157 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0094 0.0169
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0144 0.0284
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0375 0.0376
Loa Loa (eye worm) hypothetical protein 0.0025 0.0139 0.0249
Echinococcus multilocularis Phospholipase carboxylesterase 0.0026 0.0144 0.0144
Onchocerca volvulus 0.0025 0.0129 0.0455
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0004 0.0004
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0019 0.0037
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0051 0.0435 0.0783
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Onchocerca volvulus 0.0016 0.0034 0.0122
Schistosoma mansoni hypothetical protein 0.0046 0.0375 0.0373
Brugia malayi tailless protein 0.0015 0.0021 0.0034
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.02 0.2179 0.2179
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.0375 0.0375
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0021 0.0021
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.02 0.2179 0.4273
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0375 0.0376
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.02 0.2179 0.4292
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0053 0.0462 0.1269
Schistosoma mansoni gliotactin 0.0025 0.0129 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0221 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0019 0.0027
Plasmodium vivax lysophospholipase, putative 0.0026 0.0144 0.0245
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0221 0.0222
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0019 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0097 0.0978 0.1921
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0131 0.1371 0.1371
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0015 0.002 0.0003
Onchocerca volvulus 0.0046 0.0375 0.1328
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0602 0.1745
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0548
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0198 0.2157 0.7632
Giardia lamblia DNA topoisomerase III 0.0016 0.0026 0.0018
Leishmania major hypothetical protein, conserved 0.0026 0.0144 0.0284
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0042 0.0042
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0375 0.0675
Onchocerca volvulus 0.0025 0.0139 0.0491
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0221 0.0222
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0019 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0065 0.0065
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0023 0.0037
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0046 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0021 0.0021
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0308 0.0569
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Toxoplasma gondii hypothetical protein 0.0026 0.0144 0.0277
Plasmodium vivax DNA topoisomerase II, putative 0.0293 0.3268 0.6428
Plasmodium vivax PST-A protein 0.0301 0.3362 0.6615
Echinococcus granulosus serotonin transporter 0.0097 0.0978 0.098
Echinococcus granulosus g protein coupled receptor 0.0046 0.0375 0.0376
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0308 0.0569
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0131 0.1371 0.1371
Brugia malayi Protein C20orf22 0.0026 0.0144 0.0277
Schistosoma mansoni hypothetical protein 0.0044 0.0358 0.0355
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 0.0017 0.0046 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0605 0.1187
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0375 0.0675
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0221 0.0398
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.048 0.0481
Echinococcus granulosus RUN 0.0021 0.0089 0.0089
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0065 0.0605 0.1194
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0107 0.0108
Brugia malayi Doublecortin family protein 0.0021 0.0089 0.0167
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0004 0.0007
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0016 0.0026 0.0063
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0053 0.0462 0.0462
Trichomonas vaginalis spcc417.12 protein, putative 0.0025 0.0129 0.0307
Schistosoma mansoni acetylcholinesterase 0.0025 0.0129 0.0125
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0602 0.0604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0405 0.0967
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0053 0.0462 0.0462
Brugia malayi jmjC domain containing protein 0.0066 0.0619 0.1214
Schistosoma mansoni microtubule-associated protein tau 0.0739 0.8486 0.8506
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0022 0.0077
Echinococcus multilocularis dnaJ subfamily B 0.0866 0.9976 0.9976
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0198 0.2157 0.7632
Echinococcus multilocularis acetylcholinesterase 0.0145 0.154 0.154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0014 0.0004 0.0004
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0038 0.0038
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.02 0.2179 0.2184
Chlamydia trachomatis acyltransferase family protein 0.0026 0.0144 0.0546
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.004 0.0039
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0375 0.0733
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0139 0.0358
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.002 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.009 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0207 0.0495
Loa Loa (eye worm) acetylcholinesterase 1 0.0145 0.154 0.2769
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0053 0.0462 0.0902
Schistosoma mansoni neuropeptide receptor 0.0046 0.0375 0.0373
Toxoplasma gondii protein c14orf29, putative 0.0026 0.0144 0.0277
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0064 0.0115
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.1319 0.1322
Leishmania major developmentally regulated phosphoprotein-like protein 0.0015 0.002 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0254 0.0501
Schistosoma mansoni caspase-3 (C14 family) 0.0125 0.1307 0.1307
Leishmania major hypothetical protein, conserved 0.0053 0.0462 0.0911
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0175 0.0418
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0144 0.0274
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0191 0.037
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0004 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0375 0.0373
Plasmodium falciparum transporter, putative 0.0016 0.0034 0.0028
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0026 0.0144 0.0277
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.002 0.0032
Schistosoma mansoni alpha glucosidase 0.0035 0.0254 0.0251
Trypanosoma cruzi metacaspase, putative 0.0047 0.0396 0.078
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.1699 0.1704
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0221 0.0218
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0358 0.0359
Onchocerca volvulus 0.0053 0.0462 0.1635
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0004 0.0004
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0004 0.0004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.02 0.2179 0.4292
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0375 0.0376
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Schistosoma mansoni amine GPCR 0.0046 0.0375 0.0373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0305 0.0729
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0168 0.0331
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.002 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0146 0.0348
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus multilocularis bloom syndrome protein 0.0021 0.009 0.009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0221 0.0218
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0038 0.0038
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0405 0.0798
Schistosoma mansoni hypothetical protein 0.0111 0.1137 0.1137
Leishmania major hypothetical protein, unknown function 0.0014 0.0004 0.0007
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0131 0.1371 0.1375
Schistosoma mansoni coup transcription factor 0.0032 0.0221 0.0218
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0015 0.002 0.0048
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0293 0.3268 0.644
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0375 0.0675
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0396 0.078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0602 0.1745
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0462 0.0904
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.02 0.2179 0.4273
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.048 0.0946
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0004 0.0004
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0015 0.002 0.0058
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Probable two component sensor kinase 0.0015 0.002 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0028 0.0048
Brugia malayi jmjC domain containing protein 0.0017 0.0038 0.0068
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.02 0.2179 0.4292
Chlamydia trachomatis DNA gyrase subunit A 0.0063 0.0578 0.2564
Leishmania major hypothetical protein, conserved 0.0014 0.0004 0.0007
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0053 0.0462 0.1269
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0578 0.0578
Brugia malayi G protein-coupled receptor 0.0046 0.0375 0.0733
Echinococcus granulosus caspase 0.0125 0.1307 0.131
Schistosoma mansoni DNA helicase recq5 0.0021 0.009 0.0086
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0053 0.0462 0.0875
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0053 0.0462 0.2047
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Toxoplasma gondii DNA topoisomerase 2, putative 0.0293 0.3268 0.644
Trichomonas vaginalis conserved hypothetical protein 0.0301 0.3362 0.8037
Plasmodium falciparum DNA gyrase subunit A 0.0063 0.0578 0.1105
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0254 0.0607
Mycobacterium ulcerans hypothetical protein 0.0301 0.3362 1
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0375 0.0375
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0021 0.0021
Schistosoma mansoni single-minded 0.0052 0.0451 0.0449
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0254 0.0607
Brugia malayi Serotonin receptor 0.0046 0.0375 0.0733
Echinococcus multilocularis neuroligin 0.0025 0.0129 0.0129
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.1699 0.3055
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0375 0.0375
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0021 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.016 0.1713 0.308
Loa Loa (eye worm) hypothetical protein 0.0063 0.058 0.1044
Leishmania major trypanothione reductase 0.0447 0.5072 1
Plasmodium falciparum lysophospholipase, putative 0.0308 0.3448 0.6786
Schistosoma mansoni sulfide quinone reductase 0.0053 0.0462 0.046
Leishmania major DNA polymerase eta, putative 0.0016 0.0028 0.0055
Schistosoma mansoni transient receptor potential channel 0.0014 0.0004 0.00000002618
Brugia malayi CXXC zinc finger family protein 0.0061 0.0553 0.1084
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0028 0.0048
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0053 0.0462 0.0463
Mycobacterium ulcerans ferredoxin reductase 0.0053 0.0462 0.1325
Brugia malayi Flap endonuclease-1 0.0028 0.0168 0.0324
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0018
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0304 0.06
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0022 0.0022
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.3625 0.7147
Chlamydia trachomatis DNA gyrase subunit A 0.0063 0.0578 0.2564
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.1101 0.217
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0375 0.0375
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0221 0.0429
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0053 0.0462 0.1325
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0004 0.0004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Mycobacterium ulcerans hydrolase 0.0026 0.0144 0.0374
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0329 0.3687 0.7269
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.048 0.1147
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0129 0.0231
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0168 0.0424
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Entamoeba histolytica hypothetical protein 0.0026 0.0144 0.0356
Onchocerca volvulus 0.0046 0.0375 0.1328
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0375 0.0733
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0375 0.0376
Trichomonas vaginalis DNA topoisomerase II, putative 0.0293 0.3268 0.7812
Loa Loa (eye worm) histone methyltransferase 0.002 0.0076 0.0136
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0034 0.0034
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0375 0.0375
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0221 0.0398
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0032 0.0028
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0305 0.0601
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0178 0.0426
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0021 0.0034
Brugia malayi GnHR receptor homolog 0.0046 0.0375 0.0733
Leishmania major DNA damage repair protein, putative 0.0016 0.0028 0.0055
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0562
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0053 0.0462 0.0462
Mycobacterium tuberculosis Conserved protein 0.0015 0.002 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0221 0.0222
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0053 0.0462 0.0463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0219 0.0524
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0053 0.0462 0.0831
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0028 0.0048
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0065 0.0116
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0221 0.0218
Brugia malayi nuclear hormone receptor 0.0015 0.0021 0.0034
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.002 0.0048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0202 0.0202
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0375 0.0375
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.1657 0.1658
Brugia malayi Carboxylesterase family protein 0.0025 0.0129 0.0246
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0221 0.0222
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Schistosoma mansoni sodium/chloride dependent transporter 0.0097 0.0978 0.0976
Schistosoma mansoni alpha-glucosidase 0.0137 0.1441 0.1441
Echinococcus multilocularis thioredoxin glutathione reductase 0.0447 0.5072 0.5072
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0375 0.0375
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0139 0.0264
Onchocerca volvulus 0.0033 0.0231 0.0818
Leishmania major DNA topoisomerase III, putative 0.0016 0.0026 0.0052
Mycobacterium leprae Probable two component sensor kinase MprB 0.0015 0.002 0.0058
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0375 0.0376
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0462 0.0904
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0221 0.0429
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0015
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0071 0.067 0.1313
Trypanosoma cruzi heat shock protein 90, putative 0.0015 0.002 0.004
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0254 0.0493
Leishmania major cytochrome p450-like protein 0.0015 0.0019 0.0037
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.3503 1
Chlamydia trachomatis endonuclease IV 0.0082 0.0802 0.3602
Brugia malayi putative neuropeptide receptor 0.0046 0.0375 0.0733
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.1365 0.1365
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0125 0.1307 0.257
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.048 0.0481
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0076
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0005 0.0005
Echinococcus multilocularis somatostatin receptor 0.0046 0.0375 0.0375
Schistosoma mansoni netrin receptor unc5 0.0015 0.0022 0.0018
Brugia malayi hypothetical protein 0.0027 0.0157 0.0303
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.1101 0.217
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0462 0.0911
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0004 0.0007
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0396 0.0393
Onchocerca volvulus 0.0032 0.0221 0.0784
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0015 0.002 0.003
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0066 0.0608 0.1193
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0006 0.0011
Echinococcus multilocularis caspase 0.0125 0.1307 0.1307
Schistosoma mansoni amine GPCR 0.0046 0.0375 0.0373
Plasmodium vivax alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Leishmania major DNA topoisomerase ii 0.0277 0.3083 0.6078
Mycobacterium ulcerans epimerase 0.0022 0.0094 0.0225
Treponema pallidum NADH oxidase 0.02 0.2179 0.6198
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0308 0.0553
Toxoplasma gondii exonuclease III APE 0.004 0.0308 0.0599
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0301 0.3362 0.8037
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0308 0.0599
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0301 0.3362 0.8037
Mycobacterium tuberculosis Possible lysophospholipase 0.0301 0.3362 0.6625
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0042 0.0076
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Mycobacterium ulcerans hypothetical protein 0.0022 0.0094 0.0225
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0221 0.0429
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0375 0.0675
Onchocerca volvulus 0.0016 0.0026 0.0094
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0578 0.0578
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.004 0.0071
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0016 0.0026 0.0052
Brugia malayi G-protein coupled receptor 0.0046 0.0375 0.0733
Trichomonas vaginalis glutamate synthase, putative 0.0053 0.0462 0.1105
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0375 0.0375
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0021 0.0017
Giardia lamblia DNA damage repair protein 0.0016 0.0028 0.0023
Giardia lamblia DNA topoisomerase II 0.0277 0.3089 0.8812
Loa Loa (eye worm) hypothetical protein 0.0021 0.0089 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0131 0.1371 0.1371
Mycobacterium ulcerans two component regulator - sensor kinase 0.0015 0.002 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0051 0.0091
Trypanosoma cruzi metacaspase, putative 0.0047 0.0396 0.078
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0451 0.0449
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0802 0.1547
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0004 0.0004
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0004 0.0004
Mycobacterium ulcerans DNA polymerase IV 0.0108 0.1101 0.3236
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.1093 0.2613
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0065 0.0065
Toxoplasma gondii hypothetical protein 0.0063 0.058 0.1138
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0053 0.0462 0.2047
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0198 0.2157 0.7632
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0021 0.0034
Onchocerca volvulus 0.0046 0.0375 0.1328
Loa Loa (eye worm) serotonin transporter b 0.0097 0.0978 0.1757
Leishmania major monoglyceride lipase, putative 0.0301 0.3362 0.6628
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0139 0.0358
Trypanosoma cruzi NADH dehydrogenase, putative 0.0053 0.0462 0.0911
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0038 0.0068
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0021 0.0074
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0609 0.12
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0304 0.1317
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0019 0.0019
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Loa Loa (eye worm) hypothetical protein 0.0021 0.009 0.0162
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0289 0.0692
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0578 0.0576
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.02 0.2179 0.4273
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0375 0.0376
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0028 0.0048
Trichomonas vaginalis set domain proteins, putative 0.0255 0.2825 0.6752
Onchocerca volvulus 0.0014 0.0004 0.0013
Mycobacterium ulcerans two component sensor kinase MprB 0.0015 0.002 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0374 0.0737
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0028 0.0048
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0164 0.1759 0.506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0405 0.0967
Brugia malayi Serotonin receptor 0.0046 0.0375 0.0733
Loa Loa (eye worm) heat shock protein 90 0.0015 0.002 0.0036
Plasmodium vivax lysophospholipase, putative 0.0026 0.0144 0.0245
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0168 0.0424
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.163 0.469
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0602 0.06
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0375 0.0375
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.009 0.009
Echinococcus granulosus single minded 2 0.0042 0.0335 0.0336
Echinococcus granulosus dna polymerase kappa 0.0108 0.1101 0.1103
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0375 0.0376
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0015 0.002 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0145 0.154 0.2769
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0375 0.0373
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0305 0.0306
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.048 0.0946
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0231 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Entamoeba histolytica thioredoxin reductase, putative 0.0053 0.0462 0.1269
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0034 0.0035
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0375 0.0375
Mycobacterium tuberculosis Possible two component sensor kinase 0.0015 0.002 0.003
Onchocerca volvulus 0.0029 0.0179 0.0635
Loa Loa (eye worm) hypothetical protein 0.0097 0.0978 0.1757
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.02 0.2179 0.4296
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0065 0.0065
Mycobacterium ulcerans dehydrogenase 0.0053 0.0462 0.1325
Loa Loa (eye worm) hypothetical protein 0.0044 0.0358 0.0643
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0065 0.0065
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0076 0.0076
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0293 0.3268 0.644
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Brugia malayi jmjC domain containing protein 0.0063 0.0578 0.1134
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0221 0.0784
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0277 0.3083 0.6075
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0089 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Brugia malayi hypothetical protein 0.0021 0.0089 0.0167
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.1093 0.2155
Echinococcus granulosus serotonin receptor 0.0046 0.0375 0.0376
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Brugia malayi conserved hypotetical protein 0.0015 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.0198 0.216 0.3883
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0038 0.0034
Toxoplasma gondii hypothetical protein 0.0016 0.0034 0.0061
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0051 0.0442 0.0795
Brugia malayi Muscleblind-like protein 0.016 0.1713 0.3372
Echinococcus multilocularis geminin 0.0346 0.3897 0.3897
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0026 0.0144 0.0277
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0405 0.0791
Brugia malayi STAT protein, DNA binding domain containing protein 0.0141 0.1489 0.2931
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0139 0.0273
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0028 0.0024
Echinococcus multilocularis acetylcholinesterase 0.0145 0.154 0.154
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0562
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.003 0.0053
Brugia malayi Pre-SET motif family protein 0.0033 0.0231 0.0449
Brugia malayi AKH receptor 0.0046 0.0375 0.0733
Onchocerca volvulus 0.0046 0.0375 0.1328
Entamoeba histolytica hypothetical protein 0.0074 0.0703 0.196
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0254 0.0456
Plasmodium vivax thioredoxin reductase, putative 0.0447 0.5072 1
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0004 0.0007
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0375 0.0375
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0703 0.0701
Trypanosoma brucei RNA helicase, putative 0.0141 0.1492 0.2937
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0562
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0221 0.0398
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0258 0.0464
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0063 0.0578 0.1603
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0004 0.0004
Plasmodium vivax JmjC domain containing protein 0.0017 0.0038 0.0036
Leishmania major cytochrome p450-like protein 0.0015 0.0019 0.0037
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0005 0.0005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0023 0.0041
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.02 0.2179 0.4292
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0221 0.0222
Toxoplasma gondii hypothetical protein 0.0026 0.0144 0.0277
Loa Loa (eye worm) ion channel NompC 0.0014 0.0004 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0004 0.0004
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0089 0.0089
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0019 0.0027
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0114
Echinococcus multilocularis microtubule associated protein 2 0.0739 0.8486 0.8486
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0145 0.154 0.1541
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0609 0.061
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.029 0.0572
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0038 0.0068
Toxoplasma gondii selenide, water dikinase 0.0053 0.0462 0.0904
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0097 0.0978 0.0976
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0116
Plasmodium vivax amine transporter, putative 0.0016 0.0034 0.0028
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.026 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0231 0.0228
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0396 0.0773
Schistosoma mansoni disulfide oxidoreductase 0.0053 0.0462 0.046
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0019 0.0027
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0221 0.0429
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0015 0.002 0.0003
Echinococcus granulosus Phospholipase carboxylesterase 0.0026 0.0144 0.0144
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0089 0.0089
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0144 0.0344
Schistosoma mansoni opsin-like receptor 0.0046 0.0375 0.0373
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0051 0.0435 0.0852
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0277 0.3083 0.6075
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0034 0.0034
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0051 0.0442 0.0439
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Schistosoma mansoni neuropeptide receptor 0.0046 0.0375 0.0373
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0305 0.0594
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0405 0.0791
Loa Loa (eye worm) DNA topoisomerase III 0.0016 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Plasmodium falciparum DNA topoisomerase 3, putative 0.0016 0.0026 0.0013
Trypanosoma brucei DNA topoisomerase III, putative 0.0016 0.0026 0.0045
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0015 0.002 0.004
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0131 0.1371 0.1375
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0462 0.0911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Leishmania major hypothetical protein, conserved 0.0027 0.0157 0.031
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0053 0.0462 0.1325
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.02 0.2179 1
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0802 0.1547
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0221 0.0429
Loa Loa (eye worm) hypothetical protein 0.0119 0.1235 0.2221
Loa Loa (eye worm) hypothetical protein 0.0063 0.058 0.1044
Onchocerca volvulus 0.0029 0.0179 0.0635
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0025 0.0139 0.0249
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0375 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0178 0.0426
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0059 0.0531 0.1466
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.048 0.1147
Echinococcus multilocularis rho GTPase activating protein 20 0.0016 0.0026 0.0026
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.003 0.0055
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0125 0.1307 0.3854
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Brugia malayi ecdysteroid receptor 0.0032 0.0221 0.0429
Schistosoma mansoni sodium-dependent amino acid transporter 0.0016 0.0034 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0051 0.0091
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0026 0.0052
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0016 0.0026 0.003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0375 0.0373
Mycobacterium ulcerans glutamate synthase subunit beta 0.0053 0.0462 0.1325
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0019 0.0027
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0358 0.0358
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0004 0.0004
Giardia lamblia Glutamate synthase 0.0053 0.0462 0.1269
Leishmania major cytochrome p450-like protein 0.0025 0.0129 0.0254
Loa Loa (eye worm) hypothetical protein 0.0033 0.0231 0.0416
Schistosoma mansoni heat shock protein 0.0015 0.002 0.0016
Brugia malayi nuclear hormone receptor 0.0032 0.0221 0.0429
Echinococcus multilocularis transient receptor potential gamma protein 0.0014 0.0004 0.0004
Giardia lamblia DNA topoisomerase III 0.0016 0.0026 0.0018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0042
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0375 0.0675
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0396 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Entamoeba histolytica DNA topoisomerase II, putative 0.0293 0.3268 0.9324
Echinococcus granulosus g protein coupled receptor 0.0046 0.0375 0.0376
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0375 0.0373
Trypanosoma brucei unspecified product 0.0035 0.0256 0.0497
Brugia malayi polk-prov protein 0.0072 0.0687 0.1348
Mycobacterium ulcerans hypothetical protein 0.0025 0.0139 0.0358
Onchocerca volvulus 0.0016 0.0034 0.0122
Plasmodium vivax unspecified product 0.0308 0.3448 0.6786
Loa Loa (eye worm) programmed cell death 8 0.0053 0.0462 0.0831
Schistosoma mansoni cpg binding protein 0.0061 0.0553 0.0551
Plasmodium vivax alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0065 0.0155
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0405 0.0402
Mycobacterium leprae putative cytochrome p450 0.0015 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.003 0.0073
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0462 0.0904
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0175 0.0418
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0375 0.0373
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0259
Plasmodium vivax ferrodoxin reductase, putative 0.0053 0.0462 0.0875
Echinococcus granulosus geminin 0.0346 0.3897 0.3906
Schistosoma mansoni neuropeptide receptor 0.0046 0.0375 0.0373
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Brugia malayi GRF zinc finger family protein 0.0016 0.0026 0.0045
Leishmania major protein kinase, putative 0.0019 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0114
Echinococcus granulosus death domain containing protein 0.0015 0.0022 0.0022
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0764 0.0764
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0139 0.0399
Echinococcus multilocularis caspase 8 0.0047 0.0396 0.0396
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0016 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0015 0.002 0.0003
Toxoplasma gondii peptidase S15, putative 0.0026 0.0144 0.0277
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Entamoeba histolytica hypothetical protein 0.0074 0.0703 0.196
Trichomonas vaginalis helicase, putative 0.0014 0.0003 0.0007
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0026 0.0144 0.0284
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.1101 0.217
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.009 0.0215
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0375 0.0675
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0375 0.0375
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0053 0.0462 0.0875
Onchocerca volvulus 0.0046 0.0375 0.1328
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0254 0.0671
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0053 0.0462 0.1325
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0028 0.0016
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.048 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0129 0.0254
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0019 0.0027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0405 0.0406
Loa Loa (eye worm) hypothetical protein 0.0028 0.0173 0.0312
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0259
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.02 0.2179 0.6462
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0301 0.3362 0.8037
Schistosoma mansoni alpha-glucosidase 0.0137 0.1441 0.1441
Schistosoma mansoni loxhd1 0.0021 0.0089 0.0085
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.1699 0.3346
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0375 0.0375
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.048 0.132
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0015 0.002 0.003
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Brugia malayi hypoxia-induced factor 1 0.0161 0.1728 0.3402
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0004 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.3503 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0231 0.0228
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0329 0.3687 0.7269
Trypanosoma brucei monoglyceride lipase, putative 0.0301 0.3362 0.6626
Brugia malayi Melatonin receptor type 1A 0.0046 0.0375 0.0733
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0097 0.0978 0.1757
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0131 0.1371 0.1371
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus neuropeptide receptor 0.0046 0.0375 0.0376
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0053 0.0462 0.0875
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0089 0.0136
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0375 0.0373
Treponema pallidum oxidoreductase 0.0053 0.0462 0.1269
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Schistosoma mansoni cpg binding protein 0.0064 0.0594 0.0592
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0026 0.0144 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0055
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.029 0.0564
Plasmodium vivax PST-A protein 0.0026 0.0144 0.0245
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0396 0.0744
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0129 0.0244
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0021 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0021 0.0021
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0019 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0139 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0221 0.0429
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0221 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Trypanosoma brucei Heat shock protein 83, putative 0.0015 0.002 0.0032
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0005 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0221 0.0784
Echinococcus multilocularis lamin dm0 0.0029 0.0179 0.0179
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0375 0.0376
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0051 0.0442 0.0443
Brugia malayi steroid hormone receptor 0.0032 0.0221 0.0429
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0004 0.0004
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.004 0.0039
Echinococcus multilocularis musashi 0.0029 0.0179 0.0179
Leishmania major dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0619 0.062
Plasmodium vivax metacaspase 1, putative 0.0047 0.0396 0.0744
Schistosoma mansoni polycystin 1-related 0.0021 0.0089 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0375 0.0375
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0004 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0034 0.0035
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.1632 0.3218
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0026 0.0144 0.0141
Onchocerca volvulus 0.0016 0.0034 0.0122
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0097 0.0978 0.1757
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Loa Loa (eye worm) hypothetical protein 0.0198 0.216 0.3883
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Mycobacterium tuberculosis Carboxylesterase LipT 0.0025 0.0129 0.0244
Plasmodium vivax DNA gyrase subunit B, putative 0.0171 0.1839 0.3601
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0376 0.0734
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0094 0.0271
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0254 0.0254
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Plasmodium falciparum exported lipase 1 0.0026 0.0144 0.0245
Echinococcus multilocularis caspase 3 0.0078 0.0753 0.0753
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0004 0.0004
Echinococcus granulosus bloom syndrome protein 0.0021 0.009 0.009
Chlamydia trachomatis DNA gyrase subunit B 0.0171 0.1839 0.8422
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0004 0.0004
Brugia malayi MGC83647 protein 0.0026 0.0144 0.0277
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0089 0.0136
Plasmodium falciparum epoxide hydrolase 2 0.0026 0.0144 0.0245
Onchocerca volvulus 0.0046 0.0375 0.1328
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.003 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0076 0.0076
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0131 0.1371 0.2698
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium tuberculosis Probable dehydrogenase 0.0164 0.1759 0.3461
Brugia malayi PAS domain containing protein 0.0052 0.0451 0.0882
Toxoplasma gondii hypothetical protein 0.0016 0.0034 0.0061
Treponema pallidum DNA topoisomerase I (topA) 0.0016 0.0026 0.0018
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0015 0.002 0.0048
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0609 0.1764
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0144 0.0284
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0019 0.0027
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0038 0.0036
Brugia malayi Carboxylesterase family protein 0.0145 0.154 0.3031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0164 0.1759 0.3461
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0419 0.082
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0405 0.0798
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0305 0.0818
Brugia malayi Dopamine receptor protein 1 0.0046 0.0375 0.0733
Echinococcus multilocularis para nitrobenzyl esterase 0.0025 0.0129 0.0129
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.02 0.2179 0.2181
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0375 0.0376
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0004 0.0004
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0301 0.3362 0.9672
Echinococcus granulosus thioredoxin glutathione reductase 0.0447 0.5072 0.5084
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0053 0.0462 0.0904
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0376 0.0704
Schistosoma mansoni hypothetical protein 0.0046 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0119 0.1235 0.2221
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0311 0.3476 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0144 0.0344
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0396 0.0773
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0077 0.0743 0.1464
Echinococcus granulosus orexin receptor type 2 0.0046 0.0375 0.0376
Echinococcus multilocularis RUN 0.0021 0.0089 0.0089
Brugia malayi glutathione reductase 0.0447 0.5072 1
Echinococcus granulosus dna polymerase eta 0.0051 0.0442 0.0443
Entamoeba histolytica deoxycytidyl transferase, putative 0.0051 0.0442 0.1211
Trypanosoma brucei glucosidase, putative 0.0035 0.0254 0.0493
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0053 0.0462 0.0911
Loa Loa (eye worm) TOPoisomerase family member 0.0293 0.3268 0.5875
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0221 0.0398
Plasmodium falciparum amino acid transporter, putative 0.0016 0.0034 0.0028
Echinococcus granulosus neuropeptide receptor A26 0.0538 0.6138 0.6153
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0308 0.0597
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0462 0.0911
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Toxoplasma gondii hypothetical protein 0.0052 0.0452 0.0884
Trypanosoma brucei developmentally regulated phosphoprotein 0.0015 0.002 0.0032
Treponema pallidum thioredoxin reductase (trxB) 0.0053 0.0462 0.1269
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0004 0.0004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0051 0.0442 0.0439
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0028 0.0048
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.048 0.0946
Schistosoma mansoni inositol monophosphatase 0.004 0.0304 0.0301
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0125 0.1307 0.131
Brugia malayi isocitrate dehydrogenase 0.0017 0.004 0.0071
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1699 0.1699
Echinococcus multilocularis muscleblind protein 0.016 0.1713 0.1713
Echinococcus multilocularis muscleblind protein 1 0.016 0.1713 0.1713
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0221 0.0221
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0042 0.0042
Brugia malayi Inositol-1 0.004 0.0304 0.0593
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0019 0.0027
Onchocerca volvulus 0.0046 0.0375 0.1328
Loa Loa (eye worm) acetyltransferase 0.0155 0.1657 0.298
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0094 0.0176
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0375 0.0373
Leishmania major hypothetical protein, conserved 0.0053 0.0462 0.0911
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0006 0.0011
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0144 0.0344
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0764 0.0766
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0144 0.0245
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.009 0.0138
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.3625 0.7147
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.004 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0301 0.3362 0.8037
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0053 0.0462 0.1329
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0051 0.0091
Brugia malayi larval opioid receptor 0.0046 0.0375 0.0733
Loa Loa (eye worm) norepinephrine transporter 0.0097 0.0978 0.1757
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0016 0.0034 0.0037
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.0028 0.0055
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0221 0.0222
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0026 0.0144 0.0277
Brugia malayi hypothetical protein 0.0074 0.0703 0.1379
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0026 0.0144 0.0144
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.0442 0.0865
Plasmodium falciparum lysophospholipase, putative 0.0301 0.3362 0.6615
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0053 0.0462 0.0463
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0053 0.0462 0.0462
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0019 0.0027
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0053 0.0462 0.0911
Echinococcus granulosus neuropeptide s receptor 0.0538 0.6138 0.6153
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0375 0.0675
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.004 0.0036
Echinococcus multilocularis voltage dependent calcium channel 0.0131 0.1371 0.1371
Brugia malayi Dopamine receptor 0.0046 0.0375 0.0733
Leishmania major hypothetical protein, conserved 0.0026 0.0144 0.0284
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0304 0.0593
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0053 0.0462 0.1269
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0375 0.0373
Echinococcus multilocularis serotonin receptor 0.0046 0.0375 0.0375
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0019 0.0027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Loa Loa (eye worm) solute carrier family 6 member 4 0.0097 0.0978 0.1757
Schistosoma mansoni opsin-like receptor 0.0046 0.0375 0.0373
Plasmodium vivax DNA gyrase subunit A, putative 0.0063 0.0578 0.1105
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Leishmania major dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Plasmodium falciparum glutathione reductase 0.0447 0.5072 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0051 0.0435 0.0437
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0019 0.003
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0016 0.0026 0.0026
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0065 0.0155
Schistosoma mansoni amine GPCR 0.0046 0.0375 0.0373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Schistosoma mansoni sulfide quinone reductase 0.0053 0.0462 0.046
Echinococcus multilocularis heat shock protein 0.0015 0.002 0.002
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0802 0.1575
Trypanosoma brucei DNA topoisomerase ii 0.0329 0.3687 0.7267
Schistosoma mansoni histamine h1 receptor 0.0046 0.0375 0.0373
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0107 0.0204
Toxoplasma gondii DNA topoisomerase family protein 0.0016 0.0026 0.0045
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0038 0.0068
Onchocerca volvulus 0.0046 0.0375 0.1328
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0107 0.0104
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.003 0.006
Schistosoma mansoni caspase-7 (C14 family) 0.0091 0.0912 0.0911
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0157 0.031
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0157 0.0272
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0301 0.3362 0.8037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.003 0.0073
Mycobacterium ulcerans NADH dehydrogenase 0.0053 0.0462 0.1325
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Schistosoma mansoni DNA helicase recq1 0.0021 0.009 0.0086
Echinococcus granulosus microtubule associated protein 2 0.0739 0.8486 0.8507
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0462 0.0904
Plasmodium falciparum lysophospholipase, putative 0.0026 0.0144 0.0245
Echinococcus granulosus caspase 3 0.0078 0.0753 0.0754
Onchocerca volvulus 0.0046 0.0375 0.1328
Brugia malayi Carboxylesterase family protein 0.0025 0.0129 0.0246
Brugia malayi hypothetical protein 0.0015 0.0021 0.0034
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0308 0.0825
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.1101 0.217
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0032 0.0032
Schistosoma mansoni biogenic amine receptor 0.0046 0.0375 0.0373
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0139 0.0358
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0221 0.0222
Loa Loa (eye worm) hypothetical protein 0.0489 0.5562 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0289 0.0692
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0019 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0687 0.1348
Onchocerca volvulus 0.0046 0.0375 0.1328
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.1606 0.161
Echinococcus granulosus somatostatin receptor 0.0046 0.0375 0.0376
Mycobacterium ulcerans hypothetical protein 0.006 0.0547 0.1581
Entamoeba histolytica hypothetical protein 0.0074 0.0703 0.196
Plasmodium vivax SET domain protein, putative 0.0033 0.0231 0.0418
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0021 0.0017
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0051 0.0442 0.0442
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0015 0.002 0.003
Onchocerca volvulus 0.0053 0.0461 0.1632
Treponema pallidum sodium- and chloride- dependent transporter 0.0097 0.0978 0.2749
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0305 0.0305
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0022 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0021 0.0034
Schistosoma mansoni rab6-interacting 0.0021 0.0089 0.0085
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0293 0.0293
Leishmania major NADH dehydrogenase, putative 0.0053 0.0462 0.0911
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0221 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0019 0.0027
Trypanosoma cruzi DNA topoisomerase II, putative 0.0277 0.3083 0.6078
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0034 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.1632 0.3218
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0462 0.0911
Echinococcus multilocularis heat shock protein 90 0.0015 0.002 0.002
Plasmodium falciparum esterase, putative 0.0308 0.3448 0.6786
Schistosoma mansoni voltage-gated cation channel 0.0131 0.1371 0.1371
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0065 0.012
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0375 0.0376
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0304 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Schistosoma mansoni nuclear receptor 0.0015 0.0021 0.0017
Schistosoma mansoni lipoxygenase 0.0126 0.1319 0.1319
Onchocerca volvulus 0.0025 0.0129 0.0455
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0065 0.0061
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0371 0.4183 1
Brugia malayi nuclear receptor NHR-88 0.0015 0.0021 0.0034
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0034 0.0035
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.009 0.017
Plasmodium vivax PST-A protein 0.0026 0.0144 0.0245
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0015 0.002 0.0003
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0053 0.0462 0.0902
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0053 0.0462 0.0911
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0375 0.0373
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.1657 0.1657
Treponema pallidum hypothetical protein 0.006 0.0547 0.1514
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0019 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Schistosoma mansoni biogenic amine receptor 0.0046 0.0375 0.0373
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0375 0.0733
Trypanosoma brucei trypanothione reductase 0.0447 0.5072 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0153 0.1632 0.3213
Schistosoma mansoni cytochrome P450 0.0015 0.0019 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0144 0.0245
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Mycobacterium tuberculosis Probable oxidoreductase 0.0311 0.3476 0.685
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0006 0.0011
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0064 0.0086
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0053 0.0462 0.0904
Brugia malayi hypothetical protein 0.0016 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Echinococcus multilocularis serotonin transporter 0.0097 0.0978 0.0978
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0046 0.0043
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0308 0.0825
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0405 0.0798
Trypanosoma cruzi NADH dehydrogenase, putative 0.0053 0.0462 0.0911
Chlamydia trachomatis hydrolase 0.0026 0.0144 0.0546
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.1657 0.3263
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0396 0.0712
Loa Loa (eye worm) inositol-1 0.004 0.0304 0.0547
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0331 0.0893
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0028 0.0048
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0065 0.0065
Trypanosoma brucei unspecified product 0.0094 0.0937 0.1842
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0026 0.0052
Chlamydia trachomatis DNA gyrase subunit B 0.0135 0.142 0.6474
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0609 0.1764
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0304 0.0816
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0144 0.0344
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0375 0.0373
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0129 0.0231
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0405 0.0727
Mycobacterium ulcerans hypothetical protein 0.0026 0.0144 0.0374
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0259
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0256 0.0495
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0053 0.0462 0.1325
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.002 0.0048
Plasmodium falciparum metacaspase-like protein 0.0047 0.0396 0.0744
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Echinococcus multilocularis dna polymerase eta 0.0051 0.0442 0.0442
Mycobacterium ulcerans putative regultory protein 0.0015 0.002 0.0003
Toxoplasma gondii hypothetical protein 0.0308 0.3448 0.6796
Leishmania major mitochondrial DNA topoisomerase II 0.0329 0.3687 0.7269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0405 0.0967
Echinococcus multilocularis neuropeptide s receptor 0.0538 0.6138 0.6138
Leishmania major DNA polymerase kappa, putative 0.0016 0.0028 0.0055
Plasmodium falciparum lysophospholipase, putative 0.0301 0.3362 0.6615
Brugia malayi hypothetical protein 0.0046 0.0375 0.0733
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0004 0.0004
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.004 0.004
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0038 0.0068
Brugia malayi Isocitrate dehydrogenase 0.0017 0.004 0.0071
Brugia malayi neuropeptide F receptor 0.0046 0.0375 0.0733
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0021 0.0021
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0231 0.0449
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0015 0.002 0.003
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0305 0.0306
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0146 0.0348
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0016 0.0026 0.0076
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.02 0.2179 0.4273
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0375 0.0376
Entamoeba histolytica ;Alias 0.0026 0.0144 0.0356
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0231 0.0231
Mycobacterium tuberculosis Probable reductase 0.0164 0.1759 0.3461
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0061
Echinococcus multilocularis neuropeptide receptor A26 0.0538 0.6138 0.6138
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Echinococcus multilocularis folate receptor beta 0.011 0.1124 0.1124
Echinococcus granulosus g protein coupled receptor 0.0046 0.0375 0.0376
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0028 0.0016
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.009 0.0138
Onchocerca volvulus 0.0021 0.0089 0.0314
Schistosoma mansoni transient receptor potential channel 0.0014 0.0004 0.00000002618
Onchocerca volvulus 0.0061 0.0553 0.1957
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0021 0.0017
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0016 0.0026 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Toxoplasma gondii heat shock protein 90, putative 0.0015 0.002 0.0032
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0231 0.0231
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0376 0.0734
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0139 0.0358
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0144 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0221 0.0429
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0065 0.0116
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0016 0.0034 0.0035
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0025 0.0129 0.0129
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0168 0.0324
Echinococcus multilocularis calcium activated potassium channel 0.0014 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0308 0.3448 0.8243
Brugia malayi ORL1-like opioid receptor 0.0046 0.0375 0.0733
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0157 0.0303
Schistosoma mansoni hypothetical protein 0.0346 0.3897 0.3904
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0396 0.0773
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0108 0.1101 0.2632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0145 0.0347
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0478 0.0475
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0075 0.0141
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.048 0.0863
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0375 0.0375
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0375 0.0375
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0065 0.0065
Schistosoma mansoni endoplasmin 0.0015 0.002 0.0016
Trichomonas vaginalis apoptosis inducing factor, putative 0.0053 0.0462 0.1105
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0015 0.002 0.002
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.1093 0.308
Loa Loa (eye worm) carboxylesterase 0.0025 0.0129 0.0231
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0254 0.0607
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0079 0.0079
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0062
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0254 0.0607
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0139 0.0273
Echinococcus multilocularis sex peptide receptor 0.0046 0.0375 0.0375
Brugia malayi Carboxylesterase family protein 0.0025 0.0129 0.0246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Trypanosoma cruzi monoglyceride lipase, putative 0.0301 0.3362 0.6628
Brugia malayi hypothetical protein 0.0025 0.0129 0.0246
Brugia malayi Protein kinase domain containing protein 0.0016 0.0027 0.0047
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0016 0.0026 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0129 0.0328
Plasmodium falciparum glutathione reductase 0.02 0.2179 0.4273
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0004 0.0004
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0063 0.0578 0.1132
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0221 0.0218
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0065 0.0061
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0703 0.0703
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0619 0.0617
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0004 0.0004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0304 0.0593
Onchocerca volvulus 0.0021 0.0089 0.0314
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0305 0.0306
Mycobacterium ulcerans monoxygenase 0.0053 0.0462 0.1325
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0308 0.3448 0.9843
Echinococcus granulosus lamin 0.0029 0.0179 0.018
Echinococcus multilocularis sodium channel protein 0.0051 0.0443 0.0443
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0374 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0146 0.0348
Trypanosoma cruzi trypanothione reductase, putative 0.02 0.2179 0.4296
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0462 0.0904
Brugia malayi jmjC domain containing protein 0.0017 0.0038 0.0068
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0323 0.3625 0.7145
Brugia malayi sulfakinin receptor protein 0.0046 0.0375 0.0733
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0157 0.0272
Brugia malayi follicle stimulating hormone receptor 0.0292 0.3257 0.6419
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0179 0.0347
Loa Loa (eye worm) cytochrome P450 0.0015 0.0019 0.0034
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0038 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0289 0.0692
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0375 0.0375
Leishmania major mitochondrial DNA polymerase beta 0.0323 0.3625 0.7147
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0064 0.0133
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0293 0.3268 0.3275
Brugia malayi nuclear receptor RXR 0.0015 0.0021 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0289 0.0692
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0005 0.0005
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0004 0.0004
Schistosoma mansoni caspase-7 (C14 family) 0.0125 0.1307 0.1307
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0221 0.0429
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0053 0.0462 0.0904
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0015 0.002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Brugia malayi hypothetical protein 0.0175 0.1886 0.3714
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.004 0.0071
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.048 0.0478
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0053 0.0462 0.1325
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Echinococcus granulosus phd:f box containing protein 0.0017 0.0038 0.0038
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0375 0.0373
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0108 0.0205
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0375 0.0376
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0034 0.0031
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.009 0.017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0046 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0107 0.1093 0.1965
Loa Loa (eye worm) hypothetical protein 0.0029 0.0179 0.0323
Plasmodium vivax PST-A protein 0.0026 0.0144 0.0245
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0021 0.0021
Plasmodium falciparum DNA gyrase subunit B 0.0171 0.1839 0.3601
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0221 0.0218
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0053 0.0462 0.0463
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0331 0.0616
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0015 0.002 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0396 0.0946
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.003 0.006
Schistosoma mansoni endoplasmin 0.0015 0.002 0.0016
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.009 0.0177
Schistosoma mansoni hypothetical protein 0.0046 0.0375 0.0373
Mycobacterium ulcerans DNA polymerase IV 0.0108 0.1101 0.3236
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0107 0.1093 0.4969
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0131 0.1371 0.1375
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0376 0.0376
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0144 0.0344
Brugia malayi nuclear receptor RXR 0.0017 0.0042 0.0076
Echinococcus multilocularis caspase 2 0.0091 0.0912 0.0912
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0419 0.082
Entamoeba histolytica DNA topoisomerase III, putative 0.0016 0.0026 0.0018
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0375 0.0733
Echinococcus granulosus para nitrobenzyl esterase 0.0025 0.0129 0.0129
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.02 0.2179 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Brugia malayi cytochrome P450 0.0015 0.0019 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0322 0.077
Leishmania major protein kinase, putative 0.0014 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0293 0.0819
Echinococcus granulosus acetylcholinesterase 0.0145 0.154 0.1544
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.009 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0021 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0034 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0304 0.06
Brugia malayi olfactory channel protein osm-9 0.0014 0.0005 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0108 0.1101 0.2165
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0021 0.0034
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0094 0.0333
Schistosoma mansoni rab6-interacting 0.0021 0.0089 0.0085
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0076
Schistosoma mansoni DNA polymerase eta 0.0051 0.0442 0.0439
Onchocerca volvulus 0.0092 0.0916 0.3242
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.02 0.2179 0.4296
Schistosoma mansoni adenoreceptor 0.0046 0.0375 0.0373
Schistosoma mansoni hypothetical protein 0.0021 0.0089 0.0085
Plasmodium vivax PST-A protein 0.0026 0.0144 0.0245
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0375 0.0375
Trypanosoma cruzi Heat shock protein 83, putative 0.0015 0.002 0.004
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0065 0.0065
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0301 0.3362 0.9594
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0171 0.1839 0.3622
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.009 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.026 0.0622
Entamoeba histolytica DNA topoisomerase III, putative 0.0016 0.0026 0.0018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0256 0.0736
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0221 0.0398
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.003 0.0053
Echinococcus granulosus caspase 8 0.0047 0.0396 0.0397
Mycobacterium ulcerans DNA gyrase subunit A 0.0063 0.0578 0.1674
Mycobacterium leprae Probable two-component sensor kinase 0.0015 0.002 0.0058
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0311 0.3476 0.685
Echinococcus granulosus acetylcholinesterase 0.0145 0.154 0.1544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.003 0.0073
Schistosoma mansoni BC026374 protein (S09 family) 0.0025 0.0129 0.0125
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0221 0.0221
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0609 0.1191
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0094 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0221 0.0429
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0144 0.0344
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0004 0.0004
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0053 0.0462 0.0462
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0053 0.0462 0.1269
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0053 0.0462 0.0463
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0193
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0025 0.0129 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0021 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0178 0.0426
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0016 0.0026 0.0023
Trichomonas vaginalis mercuric reductase, putative 0.02 0.2179 0.5209
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0254 0.0254
Trypanosoma cruzi serine peptidase, putative 0.0026 0.0144 0.0284
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0053 0.0462 0.0911
Echinococcus granulosus folate receptor beta 0.011 0.1124 0.1127
Onchocerca volvulus 0.0015 0.0021 0.0074
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0026 0.0144 0.0277
Trypanosoma brucei heat shock protein, putative 0.0015 0.002 0.0032
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0304 0.06
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0375 0.0375
Brugia malayi Death domain containing protein 0.0015 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0375 0.0675
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0032 0.0032
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0125 0.1307 0.3854
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0129 0.0247
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0004 0.0004
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.048 0.048
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0038 0.0038
Schistosoma mansoni intermediate filament proteins 0.0029 0.0179 0.0176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.001
Brugia malayi G-protein coupled receptor 0.0046 0.0375 0.0733
Onchocerca volvulus 0.0046 0.0375 0.1328
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.002 0.0048
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0308 0.0606
Toxoplasma gondii hypothetical protein 0.011 0.1124 0.221
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Brugia malayi hypothetical protein 0.013 0.1367 0.2689
Trypanosoma brucei metacaspase MCA3 0.0047 0.0396 0.0773
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0004 0.0013
Plasmodium falciparum flap endonuclease 1 0.0028 0.0168 0.0292
Echinococcus multilocularis carboxylesterase 5A 0.0145 0.154 0.154
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0164 0.1759 0.3461
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1101 0.2165
Brugia malayi Probable DNA topoisomerase II 0.0293 0.3268 0.644
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0089 0.0089
Schistosoma mansoni inositol monophosphatase 0.004 0.0304 0.0301
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0304 0.0728
Echinococcus multilocularis 0.0015 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0144 0.0245
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0602 0.0602
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.003 0.0027
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.002 0.002
Echinococcus multilocularis lamin 0.0029 0.0179 0.0179
Schistosoma mansoni heat shock protein 0.0015 0.002 0.0016
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0375 0.0376
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0375 0.0373
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0026 0.0144 0.0245
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.048 0.1147
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0038 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0308 0.0606
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0478 0.0475
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.003 0.003
Brugia malayi Dopamine receptor protein 2 0.0046 0.0375 0.0733
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0254 0.0671
Onchocerca volvulus 0.0025 0.0129 0.0455
Loa Loa (eye worm) hypothetical protein 0.0032 0.0221 0.0398
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0375 0.0376
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0026 0.0144 0.0245
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0168 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0305 0.0729
Brugia malayi nuclear receptor NHR-88 0.0032 0.0221 0.0429
Loa Loa (eye worm) STAT protein 0.0141 0.1489 0.2677
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.003 0.006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0139 0.034
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0004 0.0007
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0038 0.0034
Plasmodium falciparum lysophospholipase, putative 0.0301 0.3362 0.6615
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.029 0.0572
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0231 0.0228
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0331 0.0893
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0311 0.3476 0.685
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Toxoplasma gondii endonuclease IV APN 0.0082 0.0802 0.1575
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0375 0.0733
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0146 0.0348
Loa Loa (eye worm) thioredoxin reductase 0.0447 0.5072 0.9119
Treponema pallidum quinoline 2-oxidoreductase 0.0059 0.0531 0.1467
Trypanosoma brucei NADH dehydrogenase 0.0053 0.0462 0.0904
Loa Loa (eye worm) hypothetical protein 0.0026 0.0144 0.0259
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0246 0.2717 0.8072
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0375 0.0376
Schistosoma mansoni lamin 0.0029 0.0179 0.0176
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.016 0.1713 0.308
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0053 0.0462 0.1269
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0016 0.0034 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0003 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0038 0.0068
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0308 0.0308
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0065 0.0061
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.009 0.017
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0512 0.092
Echinococcus granulosus dnaJ subfamily B 0.0866 0.9976 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0051 0.0443 0.0444
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0375 0.0376
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0089 0.0089
Toxoplasma gondii phospholipase/carboxylesterase 0.0026 0.0144 0.0277
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0034 0.0031
Plasmodium falciparum esterase, putative 0.0308 0.3448 0.6786
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0062
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0301 0.3362 0.8037
Trypanosoma brucei DNA polymerase IV, putative 0.0094 0.0937 0.1842
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0179 0.0323
Mycobacterium ulcerans hypothetical protein 0.0053 0.0462 0.1325
Brugia malayi Cytochrome P450 family protein 0.0025 0.0129 0.0247
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0221 0.0221
Brugia malayi MAP kinase sur-1 0.0055 0.048 0.094
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0042 0.0076
Onchocerca volvulus 0.0025 0.0129 0.0455
Giardia lamblia Thioredoxin reductase 0.0053 0.0462 0.1269
Loa Loa (eye worm) hypothetical protein 0.0077 0.0743 0.1335
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0129 0.0244
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0305 0.0302
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0131 0.1371 0.1371
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.049 0.0966
Plasmodium vivax unspecified product 0.0026 0.0144 0.0245
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.009 0.02
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0042 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.3503 0.8374
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0046 0.0111
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0157 0.0272
Trichomonas vaginalis aldehyde oxidase, putative 0.0371 0.4183 1
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0308 0.0735
Schistosoma mansoni hypothetical protein 0.0135 0.1419 0.1419
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0034 0.0031
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0305 0.0818
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0025 0.0129 0.0307
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0019 0.0027
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0131 0.1371 0.1371
Brugia malayi Carboxylesterase family protein 0.0145 0.154 0.3031
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0026 0.0144 0.0356
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0042 0.0039
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.163 0.3207
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0026 0.0144 0.0277
Trypanosoma cruzi DNA topoisomerase II, putative 0.0277 0.3083 0.6078
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0221 0.0784
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0292 0.3257 0.5855
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.048 0.048
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0004 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.02 0.2179 0.4273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0038 0.0068
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0231
Schistosoma mansoni glutamate synthase 0.0053 0.0462 0.046
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0405 0.0791
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0602 0.1745
Onchocerca volvulus 0.0046 0.0375 0.1328
Trichomonas vaginalis heat shock protein, putative 0.0015 0.002 0.0048
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0139 0.034
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0171 0.1839 0.362
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0221 0.0221
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0375 0.0375
Trypanosoma brucei heat shock protein 90, putative 0.0015 0.002 0.0032
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.004 0.0078
Brugia malayi hypothetical protein 0.0017 0.0045 0.0082
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0164 0.1759 0.3461
Entamoeba histolytica recQ family helicase, putative 0.0021 0.009 0.02
Trypanosoma brucei unspecified product 0.0035 0.0256 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0675
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0022 0.0039
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0396 0.0946
Trypanosoma brucei DNA topoisomerase IA, putative 0.0016 0.0026 0.0045
Echinococcus granulosus sodium channel protein 0.0051 0.0443 0.0444
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0038 0.0075
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0016 0.0026 0.0027
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0602 0.1181
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0221 0.0429
Echinococcus granulosus allatostatin A receptor 0.0046 0.0375 0.0376
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Trypanosoma brucei Metacaspase-4 0.0047 0.0396 0.0773
Brugia malayi Endoplasmin precursor 0.0015 0.002 0.0032
Mycobacterium ulcerans endonuclease IV 0.0082 0.0802 0.2342
Echinococcus granulosus abhydrolase domain containing 3 0.0026 0.0144 0.0144
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0305 0.0601
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0609 0.1193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0221 0.0222
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0107 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.048 0.0946
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.002 0.002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0375 0.0375
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0004 0.0004
Trypanosoma brucei metacaspase 0.0047 0.0396 0.0773
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0038 0.0075
Toxoplasma gondii hypothetical protein 0.0026 0.0144 0.0277
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.163 0.482
Trypanosoma cruzi trypanothione reductase, putative 0.0447 0.5072 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0221 0.0218
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0375 0.0375
Echinococcus granulosus calcium activated potassium channel 0.0014 0.001 0.001
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0015 0.002 0.003
Plasmodium vivax DNA topoisomerase 3, putative 0.0016 0.0026 0.0013
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.1093 0.2149
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0374 0.073
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0139 0.0358
Schistosoma mansoni zinc finger protein 0.0015 0.0021 0.0017
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0375 0.0376
Echinococcus granulosus cpg binding protein 0.0064 0.0594 0.0595
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0308 0.0308
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0064 0.0172
Trypanosoma brucei heat shock protein 90, putative 0.0015 0.002 0.0032
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0038 0.0038
Echinococcus multilocularis Ankyrin 0.0016 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0074 0.0703 0.196
Plasmodium vivax lysophospholipase, putative 0.0308 0.3448 0.6786
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0304 0.0304
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0015 0.002 0.0048
Schistosoma mansoni hypothetical protein 0.0074 0.0703 0.0701
Mycobacterium ulcerans DNA gyrase subunit B 0.0171 0.1839 0.5446
Brugia malayi hypothetical protein 0.0015 0.0021 0.0034
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.009 0.0215
Loa Loa (eye worm) hypothetical protein 0.0175 0.1886 0.3391
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0221 0.0429
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0023 0.002
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0221 0.0398
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0034 0.0062
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0375 0.0373
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0053 0.0462 0.1105
Brugia malayi DNA topoisomerase III 0.0016 0.0026 0.0045
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0042 0.0039
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0004 0.0004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0375 0.0373
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.003 0.003
Brugia malayi jmjC domain containing protein 0.0017 0.0038 0.0068
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.02 0.2179 0.4292
Schistosoma mansoni ap endonuclease 0.004 0.0308 0.0305
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.002 0.004
Trichomonas vaginalis sensor histidine kinase, putative 0.0015 0.002 0.0048
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0375 0.0373
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0802 0.1572
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0038 0.0034
Echinococcus granulosus heat shock protein 0.0015 0.002 0.002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0375 0.0675
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Schistosoma mansoni cpg binding protein 0.0064 0.0594 0.0592
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0462 0.1105
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0301 0.3362 0.8037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0003 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.02 0.2179 0.4296
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0055
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.1419 0.1419
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0053 0.0462 0.0462
Leishmania major heat shock protein 83-1 0.0015 0.002 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0375 0.0375
Trypanosoma brucei DNA polymerase IV, putative 0.0108 0.1101 0.2165
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0089 0.0089
Plasmodium falciparum thioredoxin reductase 0.0447 0.5072 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0145 0.0347
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0053 0.0462 0.2047

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10 uM Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) ChEMBL. No reference
IC50 (binding) > 10 uM Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes ChEMBL. No reference
IC50 (binding) > 10 uM Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) ChEMBL. No reference
IC50 (binding) > 10 uM Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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