Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0026 | 0.0414 | 0.0506 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.0414 | 0.0506 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0142 | 0.5874 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0142 | 0.5874 | 1 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.1818 | 0.1818 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0414 | 0.0705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0414 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Onchocerca volvulus | Cathepsin F homolog | 0.0026 | 0.0414 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0414 | 0.0705 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0026 | 0.0414 | 0.0414 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0977 | 0.0977 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.0414 | 0.0506 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0414 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.1506 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0049 | 0.1506 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0142 | 0.5874 | 0.5874 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Echinococcus multilocularis | cathepsin b | 0.0142 | 0.5874 | 0.7179 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.019 | 0.8182 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0977 | 0.1663 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Loa Loa (eye worm) | cathepsin B | 0.0049 | 0.1506 | 0.1506 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0064 | 0.0064 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0049 | 0.1506 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0049 | 0.1506 | 0.2482 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0064 | 0.0064 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0026 | 0.0414 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0026 | 0.0414 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.0026 | 0.0414 | 0.0414 |
Echinococcus granulosus | cathepsin b | 0.0142 | 0.5874 | 0.7179 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.0414 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0049 | 0.1506 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0142 | 0.5874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0026 | 0.0414 | 0.0414 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0026 | 0.0414 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Entamoeba histolytica | cysteine protease, putative | 0.0026 | 0.0414 | 1 |
Toxoplasma gondii | cathepsin B | 0.0049 | 0.1506 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.0414 | 0.0506 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.0414 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0064 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0142 | 0.5874 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0026 | 0.0414 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0414 | 0.0414 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.1818 | 0.1818 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0142 | 0.5874 | 1 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0414 | 1 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Loa Loa (eye worm) | fibroinase | 0.0026 | 0.0414 | 0.0414 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0414 | 0.0414 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Echinococcus granulosus | cathepsin b | 0.0142 | 0.5874 | 0.7179 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.0414 | 0.0506 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0026 | 0.0414 | 0.0506 |
Brugia malayi | cathepsin L-like precursor | 0.0019 | 0.0064 | 0.0064 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0064 | 0.0078 |
Echinococcus multilocularis | cathepsin b | 0.0142 | 0.5874 | 0.7179 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0414 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.0414 | 0.0414 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0064 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.019 | 0.8182 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.5874 | 0.5874 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0414 | 0.0603 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0414 | 0.0603 |
Onchocerca volvulus | 0.0026 | 0.0414 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.0414 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0064 | 0.0108 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.0414 | 0.0506 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.1506 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.0414 | 0.0414 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0977 | 0.0977 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.0414 | 0.0506 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0019 | 0.0064 | 0.0064 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0064 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0414 | 0.243 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0049 | 0.1506 | 0.2563 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0414 | 0.0603 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0414 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.1506 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.