Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.0953 | 0.0946 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0076 | 0.3436 | 0.2744 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0025 | 0.0009 | 0.0025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0025 | 0.0009 | 0.0025 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0076 | 0.3436 | 0.2744 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0593 | 0.1725 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0039 | 0.0953 | 0.2775 |
Onchocerca volvulus | Cathepsin F homolog | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0039 | 0.0953 | 0.2775 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1372 | 0.0462 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.0953 | 0.0946 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0076 | 0.3436 | 0.2744 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0076 | 0.3436 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0076 | 0.3436 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1372 | 0.0462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0051 | 0.1743 | 0.5074 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0076 | 0.3436 | 0.2744 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0051 | 0.1743 | 0.5074 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.3436 | 1 |
Plasmodium vivax | vivapain-3 | 0.0039 | 0.0953 | 0.2775 |
Entamoeba histolytica | cysteine protease, putative | 0.0076 | 0.3436 | 1 |
Plasmodium vivax | unspecified product | 0.0039 | 0.0953 | 0.2775 |
Brugia malayi | cathepsin L-like precursor | 0.0051 | 0.1743 | 0.5074 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0076 | 0.3436 | 0.2744 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1743 | 0.5074 |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0051 | 0.1743 | 0.0873 |
Brugia malayi | Cathepsin L-like precursor | 0.0051 | 0.1743 | 0.5074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0051 | 0.1743 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1646 | 0.4792 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1372 | 0.1364 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0025 | 0.0009 | 0.0025 |
Brugia malayi | Cathepsin L-like precursor | 0.0051 | 0.1743 | 0.5074 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0039 | 0.0953 | 0.2775 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0009 | 0.0025 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0039 | 0.0953 | 0.2775 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1743 | 0.5074 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0076 | 0.3436 | 1 |
Plasmodium vivax | unspecified product | 0.0025 | 0.0009 | 0.0025 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1646 | 0.4792 |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0593 | 0.0584 |
Echinococcus multilocularis | cysteine protease | 0.0076 | 0.3436 | 0.2744 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0051 | 0.1743 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0039 | 0.0953 | 0.2775 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1372 | 0.0462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0039 | 0.0953 | 0.2775 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0076 | 0.3436 | 1 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0076 | 0.3436 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0076 | 0.3436 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0025 | 0.0009 | 0.0025 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.0953 | 0.0946 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0076 | 0.3436 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0076 | 0.3436 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1372 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0076 | 0.3436 | 0.343 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.3436 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Plasmodium vivax | vivapain-2 | 0.0076 | 0.3436 | 1 |
Echinococcus multilocularis | geminin | 0.0174 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0025 | 0.0009 | 0.0025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.3436 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0076 | 0.3436 | 0.2744 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0009 | 0.0025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0039 | 0.0953 | 0.2775 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1372 | 0.3993 |
Plasmodium vivax | vivapain-1 | 0.0039 | 0.0953 | 0.2775 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0076 | 0.3436 | 1 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1372 | 0.1364 |
Toxoplasma gondii | cathepsin CPL | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0051 | 0.1743 | 0.1736 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0039 | 0.0953 | 0.2775 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0076 | 0.3436 | 0.2744 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1372 | 0.1364 |
Onchocerca volvulus | 0.0076 | 0.3436 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1372 | 0.3993 |
Echinococcus granulosus | cathepsin l1 | 0.0076 | 0.3436 | 0.2744 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1646 | 0.4792 |
Leishmania major | cysteine peptidase A (CPA) | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0025 | 0.0009 | 0.0025 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0593 | 0.1725 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.3436 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1743 | 0.5074 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0009 | 0.0025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0076 | 0.3436 | 1 |
Plasmodium vivax | vivapain-2 | 0.0076 | 0.3436 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0076 | 0.3436 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1646 | 0.4792 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.3436 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0051 | 0.1743 | 0.3182 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0076 | 0.3436 | 0.343 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0039 | 0.0953 | 0.2775 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0039 | 0.0953 | 0.2775 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.