Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0113 | 0.0817 | 0.1916 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.0943 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.025 | 0.2118 | 0.2256 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0082 | 0.0087 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0416 | 0.3707 | 0.3707 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0349 | 0.3068 | 0.3269 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0104 | 0.0111 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0051 | 0.0216 | 0.023 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.0943 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0684 | 0.6265 | 0.6674 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0084 | 0.0084 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0051 | 0.0216 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0239 | 0.0239 |
Echinococcus granulosus | tumor protein p63 | 0.0335 | 0.2931 | 0.3123 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0051 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0113 | 0.0817 | 1 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0051 | 0.0216 | 0.0216 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0349 | 0.3068 | 0.3269 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.0623 | 0.7041 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0158 | 0.1239 | 1 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1011 | 0.9387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0684 | 0.6265 | 0.6674 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0684 | 0.6265 | 0.6674 |
Echinococcus granulosus | geminin | 0.0509 | 0.4597 | 0.4897 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0084 | 0.0534 | 0.8566 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.0943 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0084 | 0.095 |
Trichomonas vaginalis | cdc25b, putative | 0.0113 | 0.0817 | 0.1916 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.1011 | 0.9387 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0416 | 0.3707 | 0.3949 |
Trichomonas vaginalis | cdc25b, putative | 0.0113 | 0.0817 | 0.1916 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.1011 | 0.9387 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0104 | 0.0111 |
Brugia malayi | Cytochrome P450 family protein | 0.0032 | 0.0038 | 0.0038 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0349 | 0.3068 | 0.3269 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0474 | 0.4262 | 1 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0084 | 0.009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0051 | 0.0216 | 0.0216 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0416 | 0.3707 | 0.3949 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0374 | 0.0399 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0416 | 0.3707 | 0.3949 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.0943 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0051 | 0.0216 | 0.0216 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0354 | 0.0354 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0103 | 0.0717 | 0.0764 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0045 | 0.0048 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0051 | 0.0216 | 0.2649 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.0113 | 0.0817 | 0.087 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0374 | 0.0399 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0051 | 0.0216 | 0.0216 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0474 | 0.4262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0106 | 0.0106 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0113 | 0.0817 | 0.1916 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0.0216 | 0.023 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0051 | 0.0216 | 0.023 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.1011 | 0.9387 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.1011 | 0.9387 | 0.9387 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.0113 | 0.0817 | 0.087 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0045 | 0.0048 |
Onchocerca volvulus | 0.0113 | 0.0817 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0354 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0045 | 0.0045 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.1011 | 0.9387 | 1 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0113 | 0.0817 | 0.1916 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0045 | 0.0048 |
Brugia malayi | hypothetical protein | 0.0107 | 0.0755 | 0.0755 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.0534 | 0.6031 |
Echinococcus multilocularis | protein patched | 0.0416 | 0.3707 | 0.3949 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0374 | 0.0399 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0313 | 0.0333 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0045 | 0.0048 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0051 | 0.0216 | 0.023 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0374 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0416 | 0.3707 | 0.3707 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.0534 | 0.6031 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0103 | 0.0717 | 0.0764 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.0113 | 0.0817 | 0.087 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0121 | 0.0885 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0051 | 0.0216 | 0.0216 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.03 | 0.2601 | 0.2771 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0461 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0051 | 0.0216 | 0.0216 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1011 | 0.9387 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0051 | 0.0216 | 0.0216 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0051 | 0.0216 | 0.0216 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0113 | 0.0817 | 0.6589 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0113 | 0.0817 | 0.6589 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0051 | 0.0216 | 0.0216 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0032 | 0.0038 | 0.004 |
Echinococcus multilocularis | tumor protein p63 | 0.0335 | 0.2931 | 0.3123 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.0755 | 0.0804 |
Echinococcus multilocularis | geminin | 0.0509 | 0.4597 | 0.4897 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0051 | 0.0216 | 0.0216 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0032 | 0.0038 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0509 | 0.4597 | 0.4897 |
Brugia malayi | Cytochrome P450 family protein | 0.0032 | 0.0038 | 0.0038 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0089 | 0.0095 |
Leishmania major | cytochrome p450-like protein | 0.0032 | 0.0038 | 0.004 |
Onchocerca volvulus | 0.0113 | 0.0817 | 1 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0354 | 0.0354 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0103 | 0.0717 | 0.0764 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.0755 | 0.0804 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0113 | 0.0817 | 0.1916 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0732 | 0.0732 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0755 | 0.6091 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0354 | 0.0354 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0349 | 0.3068 | 0.3068 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0051 | 0.0216 | 0.023 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0158 | 0.1239 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.042 | 0.042 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.1011 | 0.9387 | 0.9387 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0082 | 0.0087 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.0374 | 0.0374 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0374 | 0.0399 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.0721 | 0.0721 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0051 | 0.0216 | 0.023 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0089 | 0.0095 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0354 | 0.0354 |
Schistosoma mansoni | hypothetical protein | 0.025 | 0.2118 | 0.2256 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0817 | 0.0817 |
Brugia malayi | steroid hormone receptor | 0.0051 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0113 | 0.0817 | 1 | |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0113 | 0.0817 | 0.6589 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0051 | 0.0216 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0509 | 0.4597 | 0.4897 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0158 | 0.1239 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0416 | 0.3707 | 0.8699 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0348 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0201 | 0.0201 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0313 | 0.0333 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0354 | 0.0354 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0113 | 0.0817 | 0.0817 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0408 | 0.0408 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.025 | 0.2118 | 0.2256 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0051 | 0.0216 | 0.0216 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0201 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0045 | 0.0048 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0032 | 0.0038 | 0.0038 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0051 | 0.0216 | 0.0216 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0158 | 0.1239 | 0.2908 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.0158 | 0.1239 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0045 | 0.0048 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0349 | 0.3068 | 0.3068 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.0534 | 0.6031 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.0623 | 0.7041 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0354 | 0.0377 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0084 | 0.009 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | CHE-14 protein | 0.0416 | 0.3707 | 0.3707 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.0158 | 0.1239 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0354 | 0.0377 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0121 | 0.0885 | 0.0943 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0717 | 0.0717 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0045 | 0.0045 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0374 | 0.0399 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0354 | 0.0377 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0474 | 0.4262 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0032 | 0.0038 | 0.004 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0.0216 | 0.023 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.0534 | 0.6031 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.0534 | 0.6031 |
Chlamydia trachomatis | AMP nucleosidase | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0045 | 0.0048 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0051 | 0.0216 | 0.2649 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0051 | 0.0216 | 0.023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0051 | 0.0216 | 0.0216 |
Echinococcus granulosus | FTZ F1 alpha | 0.0051 | 0.0216 | 0.023 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0051 | 0.0216 | 0.023 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0051 | 0.0216 | 0.023 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.0534 | 0.6031 |
Brugia malayi | amidase | 0.0103 | 0.0717 | 0.0717 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0032 | 0.0038 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0755 | 0.0804 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0045 | 0.0048 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0051 | 0.0216 | 0.023 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.1011 | 0.9387 | 1 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.1011 | 0.9387 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0239 | 0.0239 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0051 | 0.0216 | 0.0216 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.7145 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0.0216 | 0.023 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0045 | 0.0048 |
Trypanosoma brucei | cytochrome P450, putative | 0.0032 | 0.0038 | 0.004 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0084 | 0.0084 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0113 | 0.0817 | 0.1916 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0416 | 0.3707 | 0.3949 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0755 | 0.6091 |
Schistosoma mansoni | coup transcription factor | 0.0051 | 0.0216 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0238 | 0.2005 | 0.2005 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0158 | 0.1239 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0158 | 0.1239 | 0.2908 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.0623 | 0.7041 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0374 | 0.0374 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0408 | 0.0408 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0113 | 0.0817 | 0.0817 |
Onchocerca volvulus | 0.0051 | 0.0216 | 0.2649 | |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0084 | 0.0679 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0051 | 0.0216 | 0.023 |
Mycobacterium ulcerans | hydrolase/amidase | 0.0563 | 0.5111 | 0.5445 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0416 | 0.3707 | 0.3949 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0105 | 0.0105 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0354 | 0.0377 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | follicle stimulating hormone receptor | 0.0238 | 0.2005 | 0.2005 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0045 | 0.0048 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0.0216 | 0.023 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0474 | 0.4262 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0354 | 0.0354 |
Schistosoma mansoni | nuclear hormone receptor | 0.0051 | 0.0216 | 0.023 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0051 | 0.0216 | 0.023 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0032 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0121 | 0.0885 | 0.0943 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0103 | 0.0717 | 0.0764 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.0755 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0049 | 0.0201 | 0.2461 | |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0416 | 0.3707 | 0.3949 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.0374 | 0.0399 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0732 | 0.0732 |
Schistosoma mansoni | thyroid hormone receptor | 0.03 | 0.2601 | 0.2771 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0051 | 0.0216 | 0.023 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0121 | 0.0885 | 0.0943 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0121 | 0.0885 | 0.0943 |
Echinococcus multilocularis | protein dispatched 1 | 0.0416 | 0.3707 | 0.3949 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0354 | 0.0377 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0067 | 0.0374 | 0.3019 |
Schistosoma mansoni | thyroid hormone receptor | 0.03 | 0.2601 | 0.2771 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.1075 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0408 | 0.0435 |
Brugia malayi | nuclear receptor NHR-88 | 0.0051 | 0.0216 | 0.0216 |
Trichomonas vaginalis | cdc25c, putative | 0.0113 | 0.0817 | 0.1916 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.0721 | 0.0721 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0354 | 0.0377 |
Brugia malayi | ecdysteroid receptor | 0.0051 | 0.0216 | 0.0216 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0755 | 0.6091 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0.0216 | 0.023 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0084 | 0.009 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0103 | 0.0717 | 0.0764 |
Brugia malayi | nuclear hormone receptor | 0.0051 | 0.0216 | 0.0216 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0051 | 0.0216 | 0.0216 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0051 | 0.0216 | 0.2649 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0.0216 | 0.023 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0051 | 0.0216 | 0.0216 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.0623 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0051 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0051 | 0.0216 | 0.0216 |
Schistosoma mansoni | patched 1 | 0.0416 | 0.3707 | 0.3949 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0817 | 0.0817 |
Schistosoma mansoni | amidase | 0.0103 | 0.0717 | 0.0764 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0158 | 0.1239 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0755 | 0.6091 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0084 | 0.0084 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0.0216 | 0.023 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.