Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0162 | 0.0143 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0162 | 0.0143 | 0.0214 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0162 | 0.0143 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0162 | 0.0143 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0162 | 0.0143 | 0.0102 |
Brugia malayi | hypothetical protein | 0.1406 | 0.2135 | 0.2102 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0162 | 0.0143 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0162 | 0.0143 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.3058 | 0.4781 | 1 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0162 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0143 | 0.0143 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0099 | 0.0041 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Brugia malayi | Peptidase family M1 containing protein | 0.0162 | 0.0143 | 0.0102 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0162 | 0.0143 | 0.0143 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0162 | 0.0143 | 0.5 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0162 | 0.0143 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.6317 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0041 | 0.0041 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0162 | 0.0143 | 0.0214 |
Brugia malayi | hypothetical protein | 0.0162 | 0.0143 | 0.0102 |
Onchocerca volvulus | 0.0162 | 0.0143 | 0.5 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0162 | 0.0143 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Onchocerca volvulus | 0.0162 | 0.0143 | 0.5 | |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0162 | 0.0143 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0162 | 0.0143 | 0.0214 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.3058 | 0.4781 | 0.4781 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Brugia malayi | TATA binding protein associated factor | 0.0162 | 0.0143 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.3058 | 0.4781 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0162 | 0.0143 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0162 | 0.0143 | 0.0214 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0162 | 0.0143 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0162 | 0.0143 | 0.0102 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0162 | 0.0143 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0162 | 0.0143 | 0.5 |
Brugia malayi | hypothetical protein | 0.0162 | 0.0143 | 0.0102 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.3058 | 0.4781 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0162 | 0.0143 | 0.5 |
Onchocerca volvulus | 0.0162 | 0.0143 | 0.5 | |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0162 | 0.0143 | 1 |
Echinococcus granulosus | aminopeptidase N | 0.0162 | 0.0143 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0162 | 0.0143 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0162 | 0.0143 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0162 | 0.0143 | 1 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0162 | 0.0143 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0162 | 0.0143 | 0.0214 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0162 | 0.0143 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0041 | 0.0041 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0099 | 0.0041 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0162 | 0.0143 | 0.0214 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0162 | 0.0143 | 0.0214 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0162 | 0.0143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | aminopeptidase N | 0.0162 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0143 | 0.0143 |
Toxoplasma gondii | aminopeptidase N protein | 0.0162 | 0.0143 | 1 |
Trypanosoma brucei | aminopeptidase, putative | 0.0162 | 0.0143 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.