Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | SET domain containing protein | 0.0013 | 0.0004 | 0.0004 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0.0143 | 1 |
Brugia malayi | Death domain containing protein | 0.0015 | 0.0019 | 0.0019 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0015 | 0.0019 | 0.000000017282 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0124 | 0.0116 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0129 | 0.0511 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0117 | 0.08 | 0.0782 |
Onchocerca volvulus | 0.0033 | 0.0154 | 0.0379 | |
Echinococcus multilocularis | chromobox protein 1 | 0.0075 | 0.0477 | 0.0469 |
Onchocerca volvulus | 0.0255 | 0.1862 | 0.5195 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0036 | 0.5 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.002 | 0.002 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0117 | 0.08 | 0.0798 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0124 | 0.0121 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0032 | 0.0143 | 0.0108 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.08 | 0.4187 |
Schistosoma mansoni | lamin | 0.0029 | 0.0124 | 0.0104 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0015 | 0.0019 | 0.0011 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.0292 | 0.0257 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0116 | 0.0793 | 0.8837 |
Brugia malayi | Uncoordinated protein 44 | 0.0015 | 0.0019 | 0.0019 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0015 | 0.0019 | 0.0011 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0044 | 0.0242 | 0.0223 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0489 | 0.3656 | 0.3655 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0032 | 0.0143 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.08 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0136 | 0.0942 | 0.0935 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0036 | 0.0034 |
Brugia malayi | Flap endonuclease-1 | 0.0028 | 0.0116 | 0.0116 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.08 | 0.4187 |
Brugia malayi | hypothetical protein | 0.0255 | 0.1858 | 0.1858 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0129 | 0.0511 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0147 | 0.0147 |
Brugia malayi | 6-phosphofructokinase | 0.0117 | 0.08 | 0.08 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0489 | 0.3656 | 0.3655 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.1314 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.002 | 0.0018 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0028 | 0.0116 | 0.0114 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0002 | 0.0002 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.0292 | 0.0284 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.5023 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0028 | 0.0116 | 0.0438 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0036 | 0.0036 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0147 | 0.0139 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0079 | 0.051 | 0.0502 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.05 | 0.3741 | 0.3736 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0075 | 0.0477 | 0.0475 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0117 | 0.08 | 0.0793 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0129 | 0.0893 | 1 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0116 | 0.0114 |
Onchocerca volvulus | 0.0477 | 0.3566 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0004 | 0.0002 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0129 | 0.0893 | 1 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0124 | 0.0116 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0224 | 0.1028 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0124 | 0.0116 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0248 | 0.1163 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0147 | 0.0112 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0224 | 0.0576 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.0292 | 0.0292 |
Echinococcus multilocularis | Ankyrin | 0.0016 | 0.002 | 0.0012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0224 | 0.1028 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0117 | 0.08 | 0.0798 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0028 | 0.0116 | 0.7439 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0147 | 0.0145 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.0403 | 0.0395 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0117 | 0.08 | 0.0798 |
Plasmodium falciparum | flap endonuclease 1 | 0.0028 | 0.0116 | 0.3125 |
Brugia malayi | Protein kinase domain containing protein | 0.0015 | 0.0019 | 0.0019 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0017 |
Echinococcus granulosus | chromobox protein 1 | 0.0075 | 0.0477 | 0.0469 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0147 | 0.0128 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0146 | 0.1026 | 0.1019 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0036 | 0.0424 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0032 | 0.0143 | 0.0108 |
Onchocerca volvulus | 0.0029 | 0.0124 | 0.0294 | |
Echinococcus granulosus | flap endonuclease 1 | 0.0028 | 0.0116 | 0.0108 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0.0143 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.05 | 0.3741 | 0.3736 |
Schistosoma mansoni | lozenge | 0.006 | 0.036 | 0.0342 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.0292 | 0.029 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0248 | 0.0645 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.4283 |
Leishmania major | trypanothione reductase | 0.0051 | 0.0292 | 0.029 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0147 | 0.0128 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.0292 | 0.0284 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0036 | 0.0034 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0489 | 0.3656 | 0.3633 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0034 |
Echinococcus granulosus | lamin | 0.0029 | 0.0124 | 0.0116 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Brugia malayi | Heterochromatin protein 1 | 0.0075 | 0.0477 | 0.0477 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.0292 | 0.2985 |
Mycobacterium tuberculosis | Probable reductase | 0.0116 | 0.0793 | 0.8837 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.0368 |
Echinococcus multilocularis | Protein lozenge | 0.006 | 0.036 | 0.0352 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0255 | 0.1858 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0224 | 0.0221 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.0403 | 0.0395 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0252 | 0.1837 | 0.1835 |
Onchocerca volvulus | 0.0052 | 0.03 | 0.079 | |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0.0143 | 0.4201 |
Loa Loa (eye worm) | phosphofructokinase | 0.0117 | 0.08 | 0.0798 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.08 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 0.3566 | 0.3565 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0028 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0002 | 0.0002 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0117 | 0.08 | 0.0798 |
Schistosoma mansoni | thyroid hormone receptor | 0.0146 | 0.1026 | 0.1009 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0489 | 0.3656 | 0.3655 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0129 | 0.0893 | 1 |
Schistosoma mansoni | chromobox protein | 0.0075 | 0.0477 | 0.0459 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.002 | 0.0018 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0015 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0119 | 0.0117 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.0292 | 1 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0489 | 0.3656 | 0.3633 |
Schistosoma mansoni | flap endonuclease-1 | 0.0025 | 0.0095 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0154 | 0.0152 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.0292 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.5023 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0116 | 0.0793 | 0.8837 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0147 | 0.0128 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.0292 | 1 |
Echinococcus granulosus | death domain containing protein | 0.0015 | 0.0019 | 0.0011 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0032 | 0.0143 | 0.0402 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0117 | 0.08 | 1 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0124 | 0.0124 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1314 | 1 | 1 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.1314 | 1 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0117 | 0.08 | 0.0793 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.1314 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0117 | 0.08 | 0.0782 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0136 | 0.0942 | 0.0935 |
Schistosoma mansoni | chromobox protein | 0.0075 | 0.0477 | 0.0459 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0028 | 0.0116 | 0.0108 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0079 | 0.051 | 0.0502 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.0384 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.0384 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0116 | 0.0793 | 0.8837 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0016 | 0.002 | 0.0001 |
Leishmania major | 0.1314 | 1 | 1 | |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0.0143 | 0.4201 |
Schistosoma mansoni | lamin | 0.0029 | 0.0124 | 0.0104 |
Brugia malayi | glutathione reductase | 0.0051 | 0.0292 | 0.0292 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.0292 | 0.029 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0116 | 0.0114 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0124 | 0.0104 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0.0143 | 0.4201 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0147 | 0.4358 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0034 |
Brugia malayi | Pre-SET motif family protein | 0.0224 | 0.1623 | 0.1623 |
Onchocerca volvulus | 0.0029 | 0.0124 | 0.0294 | |
Toxoplasma gondii | fructose-bisphospatase II | 0.1314 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0019 | 0.0017 |
Brugia malayi | hypothetical protein | 0.0477 | 0.3566 | 0.3566 |
Echinococcus granulosus | neuropeptide s receptor | 0.05 | 0.3741 | 0.3736 |
Trichomonas vaginalis | chromobox protein, putative | 0.0075 | 0.0477 | 0.2417 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0224 | 0.1623 | 0.1621 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0036 | 0.0034 |
Brugia malayi | phosphofructokinase | 0.0117 | 0.08 | 0.08 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.0403 | 0.0401 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0036 | 0.0424 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0124 | 0.0121 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0124 | 0.0124 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0124 | 0.0116 |
Schistosoma mansoni | hypothetical protein | 0.0136 | 0.0942 | 0.0925 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0129 | 0.0893 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.03 | 0.0281 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.08 | 0.4187 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1314 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0255 | 0.1861 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0015 | 0.0019 | 0.0019 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0124 | 0.0116 |
Echinococcus granulosus | Ankyrin | 0.0016 | 0.002 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0124 | 0.0121 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.0292 | 0.029 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0004 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 0.3566 | 0.3565 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.0292 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.05 | 0.3741 | 0.3736 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0116 | 0.0114 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.08 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.08 | 0.4187 |
Brugia malayi | chromobox protein homolog 3 | 0.0042 | 0.0224 | 0.0224 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0032 | 0.0143 | 0.0108 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0147 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.1858 | 0.1856 |
Loa Loa (eye worm) | runx1 | 0.006 | 0.036 | 0.0358 |
Onchocerca volvulus | 0.0044 | 0.0242 | 0.0627 | |
Plasmodium vivax | flap endonuclease 1, putative | 0.0028 | 0.0116 | 0.3125 |
Echinococcus granulosus | chromobox protein 1 | 0.0075 | 0.0477 | 0.0469 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0015 | 0.0019 | 0.0011 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0138 | 0.013 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0147 | 0.0139 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0403 | 0.5023 |
Trichomonas vaginalis | chromobox protein, putative | 0.0075 | 0.0477 | 0.2417 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Brugia malayi | follicle stimulating hormone receptor | 0.0252 | 0.1837 | 0.1837 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0117 | 0.08 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.0292 | 0.029 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0255 | 0.1858 | 0.1851 |
Brugia malayi | 6-phosphofructokinase | 0.0117 | 0.08 | 0.08 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0032 | 0.0143 | 0.1406 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0036 | 0.0034 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0028 | 0.0116 | 0.008 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0117 | 0.08 | 0.0798 |
Schistosoma mansoni | thyroid hormone receptor | 0.0146 | 0.1026 | 0.1009 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0116 | 0.0793 | 0.8837 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0116 | 0.0793 | 0.8837 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.1314 | 1 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0075 | 0.0477 | 0.0469 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.0248 | 0.1163 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0117 | 0.08 | 0.0695 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0036 | 0.0034 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.03 | 0.0281 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0032 | 0.0143 | 0.0589 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0.0143 | 0.4201 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0036 | 0.0034 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0015 | 0.0019 | 0.0011 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0036 | 0.0424 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0117 | 0.08 | 0.8918 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.1314 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.