Detailed information for compound 837238

Basic information

Technical information
  • TDR Targets ID: 837238
  • Name: 3-[2-(4-chlorophenyl)-5,7-dimethylpyrazolo[1, 5-a]pyrimidin-6-yl]-N-(2-methoxyethyl)propana mide
  • MW: 386.875 | Formula: C20H23ClN4O2
  • H donors: 1 H acceptors: 3 LogP: 2.78 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCNC(=O)CCc1c(C)nc2n(c1C)nc(c2)c1ccc(cc1)Cl
  • InChi: 1S/C20H23ClN4O2/c1-13-17(8-9-20(26)22-10-11-27-3)14(2)25-19(23-13)12-18(24-25)15-4-6-16(21)7-5-15/h4-7,12H,8-11H2,1-3H3,(H,22,26)
  • InChiKey: QLGLQCRDQXUNOV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[2-(4-chlorophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]-N-(2-methoxyethyl)propanamide
  • 3-[2-(4-chlorophenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-(2-methoxyethyl)propanamide
  • 3-[2-(4-chlorophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]-N-(2-methoxyethyl)propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0165 0.1391 0.1389
Giardia lamblia DINP protein human, muc B family 0.0019 0.0088 0.0495
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Brugia malayi hypothetical protein 0.0051 0.0371 0.0371
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0018 0.0052
Mycobacterium tuberculosis Carboxylesterase LipT 0.0028 0.0168 0.0191
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0154 0.0153
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0339 0.033
Entamoeba histolytica hypothetical protein 0.0012 0.0026 0.0102
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0056 0.0417 0.0415
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0128
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0018 0.0008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0336 0.0438
Brugia malayi nuclear receptor RXR 0.0026 0.0154 0.0154
Schistosoma mansoni DNA topoisomerase type I 0.0848 0.7467 0.7467
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0134 0.0167
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Trypanosoma brucei membrane transporter protein, putative 0.0012 0.0026 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0417 0.0417
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0018 0.0017
Trypanosoma brucei cytochrome P450, putative 0.0025 0.014 0.0175
Echinococcus multilocularis survival motor neuron protein 1 0.0706 0.6203 0.6203
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0018 0.0008
Brugia malayi isocitrate dehydrogenase 0.0047 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0182
Trypanosoma brucei unspecified product 0.0019 0.0088 0.0106
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0018 0.0008
Loa Loa (eye worm) carboxylesterase 0.0028 0.0168 0.0168
Echinococcus granulosus carboxylesterase 5A 0.0165 0.1391 0.139
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.1612 0.2149
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.0022
Schistosoma mansoni hypothetical protein 0.0017 0.0071 0.007
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0182 0.0182
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0339 0.0338
Brugia malayi steroid hormone receptor 0.0056 0.0417 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.114 0.1515
Plasmodium falciparum metacaspase-like protein 0.0089 0.0712 0.0703
Schistosoma mansoni hypothetical protein 0.0083 0.0658 0.0656
Loa Loa (eye worm) hypothetical protein 0.0028 0.0172 0.0172
Schistosoma mansoni BC026374 protein (S09 family) 0.0028 0.0168 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0054 0.04 0.0947
Onchocerca volvulus Globin homolog 0.0017 0.0071 0.0166
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0013 0.0036 0.0081
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0303 0.2614 0.2613
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0339 0.0442
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0339 0.0338
Echinococcus granulosus lamin dm0 0.0054 0.04 0.0399
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0339 0.0802
Brugia malayi hypothetical protein 0.0018 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0072 0.0557 0.0557
Loa Loa (eye worm) hypothetical protein 0.0165 0.1391 0.1391
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0177 0.0177
Treponema pallidum hypothetical protein 0.0012 0.0026 1
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0018 0.0017
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.001 0.0009
Schistosoma mansoni inositol monophosphatase 0.0036 0.0243 0.0241
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0258 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0159 0.093
Brugia malayi Hemopexin family protein 0.003 0.0188 0.0188
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0336 0.2038
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0336 0.0438
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0105 0.0096
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0587 0.5141 1
Brugia malayi N-terminal motif family protein 0.0013 0.0036 0.0036
Schistosoma mansoni ran 0.0021 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0056
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.2059 0.2059
Loa Loa (eye worm) hypothetical protein 0.0047 0.0336 0.0336
Entamoeba histolytica serine/threonine protein kinase, putative 0.019 0.1612 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0065 0.0064
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0056 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0154 0.0153
Brugia malayi hypothetical protein 0.0018 0.0082 0.0082
Onchocerca volvulus 0.0028 0.0168 0.0396
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0258 0.0258
Schistosoma mansoni smad 0.0016 0.0065 0.0064
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0154 0.0153
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0079
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0036 0.0161
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0283 0.1705
Echinococcus granulosus ras GTP exchange factor 0.0013 0.0036 0.0035
Echinococcus granulosus paired box protein pax 1 0.0009 0.0002 0.0001
Schistosoma mansoni Smad4 0.0016 0.0065 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Schistosoma mansoni hypothetical protein 0.0506 0.4422 0.4421
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.001 0.0009
Onchocerca volvulus Matrilysin homolog 0.0047 0.0339 0.0802
Giardia lamblia Kinase, PLK 0.019 0.1612 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0336 0.2038
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0082 0.0081
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Brugia malayi SET domain containing protein 0.0012 0.0024 0.0024
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0082 0.0082
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0243 0.0242
Echinococcus granulosus cpg binding protein 0.0031 0.0198 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.114 0.1515
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0088 0.0106
Brugia malayi bHLH-PAS transcription factor 0.0112 0.0912 0.0912
Brugia malayi Matrixin family protein 0.0021 0.0109 0.0109
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0235 0.2015 0.2015
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.001 0.0009
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Onchocerca volvulus 0.0017 0.0071 0.0166
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0017 0.0071 0.0071
Onchocerca volvulus 0.0017 0.0071 0.0166
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Schistosoma mansoni hypothetical protein 0.0506 0.4422 0.4421
Schistosoma mansoni gliotactin 0.0028 0.0168 0.0166
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0078 0.0425
Onchocerca volvulus 0.0011 0.0018 0.0039
Leishmania major GTP-binding protein, putative 0.0021 0.0105 0.0128
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0195 0.0248
Brugia malayi hypothetical protein 0.0018 0.0079 0.0079
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0124 0.0714
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Brugia malayi hypothetical protein 0.0017 0.0071 0.0071
Echinococcus multilocularis GPCR, family 2 0.0015 0.0056 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0417 0.0416
Loa Loa (eye worm) hypothetical protein 0.0172 0.145 0.145
Echinococcus multilocularis caspase 2 0.0172 0.145 0.145
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trypanosoma brucei unspecified product 0.0013 0.0036 0.0035
Brugia malayi hypothetical protein 0.0026 0.0154 0.0154
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0371 0.0362
Plasmodium vivax topoisomerase I, putative 0.1132 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Brugia malayi Carboxylesterase family protein 0.0028 0.0168 0.0168
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Echinococcus multilocularis acetylcholinesterase 0.0165 0.1391 0.139
Loa Loa (eye worm) CYP4Cod1 0.0025 0.014 0.014
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0258 0.0334
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0283 0.0669
Onchocerca volvulus 0.0028 0.0168 0.0396
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0018 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0079 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.114 0.1515
Schistosoma mansoni retinoic acid receptor RXR 0.0056 0.0417 0.0415
Leishmania major DNA polymerase eta, putative 0.0044 0.0311 0.0404
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0065 0.0496 0.0496
Echinococcus granulosus FTZ F1 alpha 0.0056 0.0417 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0336 0.2038
Mycobacterium ulcerans hydrolase 0.0026 0.015 0.0273
Leishmania major hypothetical protein, conserved 0.0137 0.114 0.1515
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0056 0.0417 0.0417
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0065 0.0064
Leishmania major hypothetical protein, conserved 0.0023 0.0123 0.0152
Schistosoma mansoni hypothetical protein 0.0421 0.3669 0.3668
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0182
Echinococcus multilocularis Smad4 0.0016 0.0065 0.0064
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0243 0.1454
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0371 0.0362
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.114 0.1515
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0056 0.0417 0.0417
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0417 0.0416
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0082 0.0082
Brugia malayi bZIP transcription factor family protein 0.0086 0.0689 0.0689
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0712 0.0703
Trypanosoma brucei metacaspase 5, putative 0.0089 0.0712 0.0942
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0105
Trichomonas vaginalis hypothetical protein 0.0011 0.0018 0.0052
Echinococcus multilocularis DNA topoisomerase 1 0.1132 1 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0243 0.1454
Brugia malayi MH1 domain containing protein 0.0016 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0258 0.1556
Loa Loa (eye worm) carboxylesterase 0.0165 0.1391 0.1391
Brugia malayi hypothetical protein 0.0033 0.0211 0.0211
Brugia malayi hypothetical protein 0.0068 0.0524 0.0524
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0013 0.0036 0.0034
Schistosoma mansoni aryl hydrocarbon receptor 0.0158 0.1329 0.1328
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0172 0.0217
Schistosoma mansoni hypothetical protein 0.007 0.0545 0.0544
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0056 0.0417 0.0415
Brugia malayi MH2 domain containing protein 0.024 0.2059 0.2059
Schistosoma mansoni smad1 5 8 and 0.0016 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0522 0.0522
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Echinococcus multilocularis smad 0.0016 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0021 0.0109 0.0109
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Brugia malayi Pax transcription factor protein 2 0.0482 0.4208 0.4208
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Trypanosoma cruzi metacaspase, putative 0.0089 0.0712 0.0942
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0351 0.0351
Onchocerca volvulus Cell death protein 3 homolog 0.0172 0.145 0.3445
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0257 0.0608
Loa Loa (eye worm) matrixin family protein 0.0047 0.0339 0.0339
Echinococcus multilocularis acetylcholinesterase 0.0165 0.1391 0.139
Loa Loa (eye worm) hypothetical protein 0.0013 0.0036 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0065 0.0064
Trichomonas vaginalis hypothetical protein 0.0035 0.023 0.1374
Brugia malayi paired box protein 0.0009 0.0002 0.0002
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0258 0.0258
Mycobacterium ulcerans putative regulatory protein 0.0112 0.0912 0.1759
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.014 0.014
Plasmodium falciparum multidrug efflux pump, putative 0.0012 0.0026 0.0017
Schistosoma mansoni DNA ligase IV 0.001 0.001 0.0008
Brugia malayi serine/threonine-protein kinase plk-2 0.019 0.1612 0.1612
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0018 0.0008
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0154 0.0154
Brugia malayi vab-3 gene. 0.0009 0.0002 0.0002
Echinococcus multilocularis apoptotic protease activating factor 1 0.0083 0.0658 0.0657
Brugia malayi Carboxylesterase family protein 0.0165 0.1391 0.1391
Echinococcus granulosus para nitrobenzyl esterase 0.0028 0.0168 0.0167
Loa Loa (eye worm) hypothetical protein 0.0018 0.0082 0.0082
Echinococcus granulosus aryl hydrocarbon receptor 0.0065 0.0496 0.0495
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0258 0.1552
Schistosoma mansoni importin beta-1 0.0028 0.0172 0.017
Echinococcus multilocularis carboxylesterase 5A 0.0165 0.1391 0.139
Onchocerca volvulus 0.0056 0.0417 0.0987
Brugia malayi ecdysone receptor 0.0026 0.0154 0.0154
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0522 0.3198
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0088 0.0105
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0105 0.0096
Trypanosoma brucei metacaspase 0.0089 0.0712 0.0942
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0339 0.0339
Brugia malayi tailless protein 0.0026 0.0154 0.0154
Echinococcus multilocularis geminin 0.0506 0.4422 0.4422
Echinococcus granulosus apoptotic protease activating factor 1 0.0083 0.0658 0.0657
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0243 0.1454
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0056 0.0055
Onchocerca volvulus 0.0017 0.0071 0.0166
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0339 0.0442
Brugia malayi 'Paired box' domain containing protein 0.0009 0.0002 0.0002
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0065 0.0064
Plasmodium vivax importin-beta 2, putative 0.0028 0.0172 0.0162
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0154 0.0153
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0082 0.0082
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0417 0.0416
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0311 0.0405
Entamoeba histolytica hypothetical protein 0.0013 0.0036 0.0161
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0522 0.3198
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.001 0.001
Schistosoma mansoni intermediate filament proteins 0.0054 0.04 0.0398
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0154 0.0152
Echinococcus granulosus DNA topoisomerase 1 0.1132 1 1
Mycobacterium ulcerans hypothetical protein 0.0024 0.0134 0.0242
Loa Loa (eye worm) hypothetical protein 0.0288 0.2483 0.2483
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0128
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0047 0.0336 0.0336
Leishmania major hypothetical protein, conserved 0.0209 0.1782 0.2376
Loa Loa (eye worm) steroid hormone receptor 0.0056 0.0417 0.0417
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0052
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.014 0.014
Brugia malayi nuclear receptor NHR-67 0.0026 0.0154 0.0154
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0154 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0035
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0056 0.0417 0.0416
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0096
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Brugia malayi nuclear hormone receptor 0.0056 0.0417 0.0417
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0052
Loa Loa (eye worm) helicase 0.0011 0.0018 0.0018
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0243 0.0454
Entamoeba histolytica hypothetical protein 0.0107 0.0875 0.5402
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0018 0.0008
Loa Loa (eye worm) paired box protein 0.0009 0.0002 0.0002
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Onchocerca volvulus 0.0017 0.0071 0.0166
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0056 0.0417 0.0416
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0417 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0258 0.1552
Leishmania major cytochrome p450-like protein 0.0025 0.014 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0056 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0036 0.0034
Onchocerca volvulus 0.0068 0.0524 0.1242
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.1782 0.2376
Echinococcus multilocularis paired box protein pax 1 0.0009 0.0002 0.0001
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis adenylate cyclase, putative 0.0047 0.0336 0.2038
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0182 0.0182
Schistosoma mansoni lamin 0.0054 0.04 0.0398
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0082 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0417 0.0417
Brugia malayi RasGEF domain containing protein 0.0013 0.0036 0.0036
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0018 0.0018
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus jun protein 0.0086 0.0689 0.0688
Brugia malayi hypothetical protein 0.0072 0.0557 0.0557
Brugia malayi Carboxylesterase family protein 0.0028 0.0168 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0258 0.0258
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0033 0.0032
Schistosoma mansoni smad1 5 8 and 0.0016 0.0065 0.0064
Schistosoma mansoni tsg101-related 0.0049 0.0353 0.0352
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0417 0.0417
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0339 0.0529
Loa Loa (eye worm) DR-78 0.0026 0.0154 0.0154
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0082 0.0081
Leishmania major protein kinase, putative 0.0055 0.0413 0.0541
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0182 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0018 0.0008
Echinococcus granulosus chromobox protein 2 0.0011 0.0018 0.0017
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0258 0.0258
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0875 0.0875
Echinococcus multilocularis chromobox protein 2 0.0011 0.0018 0.0017
Trypanosoma brucei membrane transporter protein, putative 0.0137 0.114 0.1515
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Brugia malayi Cytochrome P450 family protein 0.0025 0.014 0.014
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0018 0.0017
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0036 0.0034
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0285 0.2452 0.3276
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0056 0.0417 0.0417
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0036 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.0022
Leishmania major DNA topoisomerase type IB small subunit 0.0285 0.2452 0.3275
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0056 0.0055
Onchocerca volvulus 0.0065 0.0496 0.1175
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.019 0.1612 0.1612
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Echinococcus granulosus intermediate filament protein 0.0054 0.04 0.0399
Echinococcus multilocularis nibrin 0.001 0.001 0.0009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0258 0.0258
Echinococcus multilocularis musashi 0.0054 0.04 0.0399
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0182
Trypanosoma cruzi metacaspase, putative 0.0089 0.0712 0.0942
Brugia malayi Matrixin family protein 0.0021 0.0109 0.0109
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0848 0.7467 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0154 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0035
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0052
Brugia malayi Inositol-1 0.0036 0.0243 0.0243
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Echinococcus multilocularis caspase 3 0.0146 0.1223 0.1222
Entamoeba histolytica ABC transporter, putative 0.001 0.001 0.0002
Schistosoma mansoni kinase 0.0097 0.078 0.0778
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0102
Giardia lamblia Na+ driven multidrug efflux pump 0.0012 0.0026 0.0109
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.0052
Echinococcus granulosus Chromo domain 0.0011 0.0018 0.0017
Brugia malayi RNA, U transporter 1 0.0081 0.0637 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.005 0.0252
Echinococcus granulosus kelch ECH associated protein 1 like 0.0097 0.0785 0.0784
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0035
Echinococcus multilocularis lamin 0.0054 0.04 0.0399
Onchocerca volvulus 0.0482 0.4208 1
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0134 0.0133
Echinococcus granulosus paired box protein pax 6 0.0009 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0012 0.0026 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.0022
Trypanosoma cruzi membrane transporter protein, putative 0.0012 0.0026 0.0022
Brugia malayi Smad1 0.0016 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Trypanosoma brucei Metacaspase-4 0.0089 0.0712 0.0942
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.001 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0056 0.0417 0.0417
Brugia malayi Globin family protein 0.0017 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0051 0.0371 0.0484
Loa Loa (eye worm) acetylcholinesterase 1 0.0165 0.1391 0.1391
Leishmania major hypothetical protein, conserved 0.0137 0.114 0.1515
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0125 0.1033 0.1032
Brugia malayi intermediate filament protein 0.0054 0.04 0.04
Onchocerca volvulus 0.0011 0.0018 0.0039
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.0342 0.0445
Echinococcus granulosus caspase 2 0.0172 0.145 0.145
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0351 0.0351
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0372 0.3229 0.7673
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0079 0.0077
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0088 0.0491
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Plasmodium vivax metacaspase 1, putative 0.0089 0.0712 0.0703
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0086 0.0689 0.0688
Brugia malayi Globin family protein 0.0017 0.0071 0.0071
Echinococcus multilocularis caspase 8 0.0089 0.0712 0.0711
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0052
Echinococcus granulosus Chromobox protein 3 0.0011 0.0018 0.0017
Brugia malayi hypothetical protein 0.0011 0.0018 0.0018
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0082 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Echinococcus multilocularis FTZ F1 alpha 0.0056 0.0417 0.0416
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0028 0.0168 0.0988
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0159 0.093
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Leishmania major DNA polymerase eta, putative 0.0031 0.0195 0.0248
Brugia malayi MH2 domain containing protein 0.0016 0.0065 0.0065
Echinococcus granulosus paired box protein pax 6 0.0009 0.0002 0.0001
Schistosoma mansoni RAR-like nuclear receptor 0.0056 0.0417 0.0415
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Echinococcus granulosus replication factor c subunit 1 0.001 0.001 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0078 0.0425
Echinococcus granulosus chromobox protein 1 0.0068 0.0522 0.0521
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0084 0.0668 0.0668
Loa Loa (eye worm) hypothetical protein 0.003 0.0184 0.0184
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0195 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0257 0.1545
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0151 0.015
Brugia malayi 'Paired box' domain containing protein 0.0009 0.0002 0.0002
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0154 0.0154
Schistosoma mansoni neuroligin 3 (S09 family) 0.0028 0.0168 0.0166
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.0052
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0134 0.0242
Echinococcus granulosus dna polymerase kappa 0.0019 0.0088 0.0087
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0018 0.0018
Trichomonas vaginalis guanylate cyclase, putative 0.0047 0.0336 0.2038
Brugia malayi hypothetical protein 0.0017 0.0071 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0154 0.0153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0417 0.0415
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0033 0.0032
Entamoeba histolytica hypothetical protein 0.0107 0.0875 0.5402
Brugia malayi nuclear receptor RXR 0.003 0.0182 0.0182
Trypanosoma brucei membrane transporter protein, putative 0.0137 0.114 0.1515
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trypanosoma brucei hypothetical protein, conserved 0.0209 0.1782 0.2376
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0154 0.0152
Trichomonas vaginalis spcc417.12 protein, putative 0.0028 0.0168 0.0988
Brugia malayi nuclear receptor NHR-88 0.0026 0.0154 0.0154
Schistosoma mansoni multidrug resistance protein 0.0012 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0311 0.0311
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0082 0.0081
Brugia malayi Cytochrome P450 family protein 0.0025 0.014 0.014
Echinococcus granulosus GPCR family 2 0.0015 0.0056 0.0055
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0047 0.0336 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0417 0.0417
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Leishmania major protein kinase, putative 0.0047 0.0342 0.0445
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0154 0.0153
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0172 0.0171
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0712 0.0703
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0168 0.0166
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0258 0.0334
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0088 0.0153
Onchocerca volvulus 0.0028 0.0168 0.0396
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0339 0.0339
Schistosoma mansoni DNA topoisomerase type I 0.1132 1 1
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0079 0.0079
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0052
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Echinococcus multilocularis BC026374 protein (S09 family) 0.0028 0.0168 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0088 0.0034
Mycobacterium ulcerans DNA-damage-inducible protein F DinF 0.0012 0.0026 0.0033
Schistosoma mansoni caspase-3 (C14 family) 0.0235 0.2015 0.2014
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0082 0.0082
Brugia malayi CXXC zinc finger family protein 0.003 0.0183 0.0183
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0339 0.0338
Onchocerca volvulus 0.0021 0.0109 0.0254
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0088 0.0106
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0168 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0757 0.4666
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Echinococcus granulosus Protein son of sevenless 0.0013 0.0036 0.0035
Schistosoma mansoni inositol monophosphatase 0.0036 0.0243 0.0241
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0028 0.0168 0.0167
Onchocerca volvulus Matrilysin homolog 0.0021 0.0109 0.0254
Loa Loa (eye worm) hypothetical protein 0.0038 0.0257 0.0257
Entamoeba histolytica hypothetical protein 0.0012 0.0026 0.0102
Echinococcus granulosus kelch ECH associated protein 1 like 0.0097 0.0785 0.0784
Echinococcus multilocularis snurportin 1 0.0303 0.2614 0.2613
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0418 0.0409
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0417 0.0415
Brugia malayi Matrixin family protein 0.0021 0.0109 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0258 0.0257
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0122 0.0121
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0013 0.0036 0.0035
Schistosoma mansoni lamin 0.0054 0.04 0.0398
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0079
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0339 0.0442
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0056 0.0417 0.0417
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Echinococcus granulosus nibrin 0.001 0.001 0.0009
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0056 0.0417 0.0416
Schistosoma mansoni nuclear receptor 0.0026 0.0154 0.0152
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0088 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0757 0.4666
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0209 0.0271
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0082 0.0081
Brugia malayi Protein cec-1. 0.0011 0.0018 0.0018
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Loa Loa (eye worm) inositol-1 0.0036 0.0243 0.0243
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0072 0.0557 0.0556
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0587 0.5141 1
Trypanosoma cruzi metacaspase, putative 0.0089 0.0712 0.0942
Brugia malayi hypothetical protein 0.001 0.001 0.001
Brugia malayi hypothetical protein 0.001 0.001 0.001
Schistosoma mansoni survival motor neuron protein 0.0144 0.1201 0.12
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0243 0.0313
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.005 0.0252
Echinococcus granulosus BC026374 protein S09 family 0.0028 0.0168 0.0167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0109 0.0109
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0082 0.0081
Schistosoma mansoni chromobox protein 0.0011 0.0018 0.0017
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0122 0.0121
Brugia malayi photoreceptor-specific nuclear receptor 0.0288 0.2483 0.2483
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0258 0.0258
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Onchocerca volvulus Bile acid receptor homolog 0.0056 0.0417 0.0987
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0028 0.0168 0.0309
Schistosoma mansoni topbp1 0.001 0.001 0.0008
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0339 0.033
Brugia malayi nuclear hormone receptor 0.0026 0.0154 0.0154
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni jun-related protein 0.007 0.0545 0.0544
Loa Loa (eye worm) hypothetical protein 0.0026 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0109 0.0109
Brugia malayi N-terminal motif family protein 0.0013 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0082 0.0082
Onchocerca volvulus 0.003 0.0188 0.0442
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0071
Echinococcus multilocularis replication factor c subunit 1 0.001 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.2614 0.2614
Schistosoma mansoni tsg101-related 0.006 0.045 0.0449
Schistosoma mansoni acetylcholinesterase 0.0028 0.0168 0.0166
Giardia lamblia Replication factor C, subunit 1 0.001 0.001 0.0005
Schistosoma mansoni globin X 0.0017 0.0071 0.007
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0049 0.0353 0.2143
Schistosoma mansoni multidrug resistance protein 0.0137 0.114 0.1138
Trypanosoma brucei unspecified product 0.0013 0.0036 0.0035
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0154 0.0152
Toxoplasma gondii DNA topoisomerase I, putative 0.1132 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0243 0.0313
Schistosoma mansoni dishevelled 0.0018 0.0082 0.0081
Onchocerca volvulus 0.0026 0.0154 0.0362
Onchocerca volvulus 0.0028 0.0168 0.0396
Schistosoma mansoni caspase-7 (C14 family) 0.0172 0.145 0.1449
Brugia malayi Gooseberry protein 0.0009 0.0002 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0047 0.0336 0.2038
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Trypanosoma cruzi hypothetical protein 0.0013 0.0036 0.0035
Echinococcus granulosus lamin 0.0054 0.04 0.0399
Brugia malayi chromobox protein homolog 3 0.0038 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni tsg101-related 0.006 0.045 0.0449
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0018 0.0018
Echinococcus multilocularis para nitrobenzyl esterase 0.0028 0.0168 0.0167
Schistosoma mansoni dishevelled 0.0018 0.0082 0.0081
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.0342 0.0445
Brugia malayi hypothetical protein 0.0026 0.0154 0.0154
Onchocerca volvulus 0.0018 0.0082 0.0192
Onchocerca volvulus Protein ultraspiracle homolog 0.0056 0.0417 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0257 0.1545
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Onchocerca volvulus 0.0083 0.0658 0.156
Loa Loa (eye worm) Smad1 0.0016 0.0065 0.0065
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Echinococcus multilocularis neuroligin 0.0028 0.0168 0.0167
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0137 0.114 0.1139
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0088 0.0088
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0154 0.0154
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0848 0.7467 1
Schistosoma mansoni myoglobin 1 0.0017 0.0071 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0258 0.1552
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Brugia malayi hypothetical protein 0.0017 0.0071 0.0071
Brugia malayi MH1 domain containing protein 0.0016 0.0065 0.0065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0046 0.0225
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0154 0.0153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0056 0.0417 0.0417
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0086 0.0689 0.0688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0417 0.0416
Brugia malayi 'Paired box' domain containing protein 0.0009 0.0002 0.0002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0105 0.0104
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0077 0.0607 0.0607
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0105 0.0128
Echinococcus granulosus acetylcholinesterase 0.0165 0.1391 0.139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0056 0.0417 0.0417
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0243 0.0233
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.0022
Entamoeba histolytica hypothetical protein 0.0012 0.0026 0.0102
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0022
Echinococcus multilocularis chromobox protein 1 0.0068 0.0522 0.0521
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0154 0.0154
Schistosoma mansoni chromobox protein 0.0068 0.0522 0.0521
Schistosoma mansoni hypothetical protein 0.0144 0.1201 0.12
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0154 0.0153
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.014 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0056 0.0417 0.0416
Brugia malayi Cell death protein 3 precursor 0.0172 0.145 0.145
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0214 0.0214
Onchocerca volvulus 0.0112 0.0912 0.2165
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0235 0.2015 0.2015
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0065 0.0064
Loa Loa (eye worm) DNA topoisomerase I 0.1132 1 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0677 0.0677
Echinococcus multilocularis jun protein 0.0086 0.0689 0.0688
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0082 0.0081
Echinococcus granulosus survival motor neuron protein 1 0.0706 0.6203 0.6203
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0056 0.0055
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0065 0.0065
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni DNA topoisomerase type I 0.0848 0.7467 0.7467
Schistosoma mansoni cpg binding protein 0.0031 0.0198 0.0196
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0089 0.0712 0.0712
Schistosoma mansoni dep domain containing protein 0.0018 0.0082 0.0081
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.019 0.1612 0.1612
Plasmodium falciparum importin beta, putative 0.0028 0.0172 0.0162
Trypanosoma cruzi metacaspase, putative 0.0089 0.0712 0.0942
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0712 0.0703
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0243 0.0242
Giardia lamblia Na+ driven multidrug efflux pump 0.0012 0.0026 0.0109
Brugia malayi PAS domain containing protein 0.0158 0.1329 0.1329
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.1612 0.2149
Brugia malayi hypothetical protein 0.0107 0.0875 0.0875
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0088 0.0491
Onchocerca volvulus 0.0026 0.0154 0.0362
Echinococcus multilocularis chromobox protein 1 0.0068 0.0522 0.0521
Loa Loa (eye worm) hypothetical protein 0.0038 0.0258 0.0258
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0172 0.0162
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Brugia malayi hypothetical protein 0.0028 0.0168 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Brugia malayi topoisomerase 0.001 0.001 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Echinococcus multilocularis ecdysone induced protein 78C 0.0056 0.0417 0.0416
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Brugia malayi N-terminal motif family protein 0.0372 0.3229 0.3229
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.001 0.0009
Trichomonas vaginalis ran, putative 0.0021 0.0105 0.0596
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.015 0.015
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0168 0.0191
Onchocerca volvulus 0.003 0.0183 0.0431
Loa Loa (eye worm) pax transcription factor protein 2 0.0482 0.4208 0.4208
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0089 0.0712 0.4384
Schistosoma mansoni DNA polymerase eta 0.0044 0.0311 0.031
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Entamoeba histolytica hypothetical protein 0.0107 0.0875 0.5402
Schistosoma mansoni ran 0.0021 0.0105 0.0104
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0018 0.0008
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0214 0.0214
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0339 0.0442
Schistosoma mansoni ras GTP exchange factor 0.0013 0.0036 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Echinococcus multilocularis Protein son of sevenless 0.0013 0.0036 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0124 0.0714
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0056 0.0417 0.0416
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0137 0.114 0.1139
Trypanosoma brucei membrane transporter protein, putative 0.0137 0.114 0.1515
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0124 0.0153
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0371 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0417 0.0417
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0052
Leishmania major adenylate cyclase-like protein 0.0017 0.0071 0.0082
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0154 0.0154
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0258 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0056 0.0417 0.0417
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.015 0.0273
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0077 0.0607 0.0607
Plasmodium falciparum topoisomerase I 0.1132 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0056 0.0417 0.0416
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0082 0.0082
Echinococcus granulosus kelch ECH associated protein 1 0.0097 0.0785 0.0784
Brugia malayi hypothetical protein 0.0018 0.0079 0.0079
Echinococcus multilocularis lamin dm0 0.0054 0.04 0.0399
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Schistosoma mansoni caspase-7 (C14 family) 0.0235 0.2015 0.2014
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0072 0.0557 0.0556
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0134 0.0242
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0134 0.0133
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0056 0.0417 0.0416
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0123 0.0152
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0124 0.0714
Echinococcus multilocularis Kelch repeat type 1 0.0098 0.0788 0.0787
Schistosoma mansoni topbp1 0.001 0.001 0.0008
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0182 0.0181
Loa Loa (eye worm) hypothetical protein 0.0706 0.6203 0.6203
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0336 0.2038
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0182 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.001 0.001 0.0008
Trypanosoma cruzi membrane transporter protein, putative 0.0137 0.114 0.1515
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0102
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0088 0.0087
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0088 0.0087
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0339 0.0442
Onchocerca volvulus 0.0028 0.0168 0.0396
Loa Loa (eye worm) hypothetical protein 0.0089 0.0712 0.0712
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0154 0.0154
Brugia malayi Heterochromatin protein 1 0.0068 0.0522 0.0522
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0056 0.0056
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0311 0.0311
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0154 0.0153
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0154 0.0153
Echinococcus multilocularis ras GTP exchange factor 0.0013 0.0036 0.0035
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0123 0.0152
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0134 0.0167
Brugia malayi nuclear receptor NHR-88 0.0056 0.0417 0.0417
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.04 0.04
Echinococcus granulosus acetylcholinesterase 0.0165 0.1391 0.139
Echinococcus granulosus chromobox protein 1 0.0068 0.0522 0.0521
Loa Loa (eye worm) globin family protein 0.0017 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0258 0.1552
Echinococcus granulosus Smad4 0.0016 0.0065 0.0064
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0285 0.2452 0.3276
Echinococcus granulosus serine:threonine protein kinase PLK1 0.019 0.1612 0.1612
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0056 0.0417 0.0416
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0056 0.0417 0.0415
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0013 0.0036 0.0035
Brugia malayi Carboxylesterase family protein 0.0165 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0079
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0056 0.0417 0.0415
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Onchocerca volvulus 0.0012 0.0024 0.0053
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0371 0.0485
Mycobacterium ulcerans hypothetical protein 0.0024 0.0134 0.0242
Echinococcus multilocularis Chromo domain 0.0011 0.0018 0.0017
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0371 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0336 0.2038
Echinococcus granulosus importin subunit beta 1 0.0028 0.0172 0.0171
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0371 0.0485
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0056 0.0417 0.0417
Onchocerca volvulus Serine\/threonine kinase homolog 0.019 0.1612 0.3829
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0339 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.001 0.0008
Trypanosoma brucei metacaspase MCA2 0.0089 0.0712 0.0942
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0013 0.0036 0.0035
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0134 0.0775
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0154 0.0152
Echinococcus multilocularis caspase 0.0235 0.2015 0.2015
Mycobacterium leprae Possible regulatory protein 0.0047 0.0336 0.0637
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0144 0.1201 0.2852
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.001 0.0001
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0052
Echinococcus granulosus dnaJ subfamily B 0.0421 0.3669 0.3669
Echinococcus multilocularis paired box protein pax 6 0.0009 0.0002 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.014 0.0175
Brugia malayi RasGEF domain containing protein 0.0013 0.0036 0.0036
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0677 0.4161
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0677 0.4161
Schistosoma mansoni hypothetical protein 0.0023 0.0122 0.012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0056 0.0417 0.0416
Echinococcus granulosus caspase 8 0.0089 0.0712 0.0711
Schistosoma mansoni cpg binding protein 0.003 0.0183 0.0181
Onchocerca volvulus 0.0013 0.0036 0.0081
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0875 0.0874
Echinococcus granulosus paired box gene 3/7 (eyeless, eyegone, twin of eyeless) 0.0009 0.0002 0.0001
Echinococcus multilocularis son of sevenless 1 0.0013 0.0036 0.0035
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Trypanosoma brucei polo-like protein kinase 0.019 0.1612 0.2149
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0172 0.0217
Trypanosoma cruzi metacaspase 5, putative 0.0089 0.0712 0.0942
Loa Loa (eye worm) hypothetical protein 0.0083 0.0658 0.0658
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0077
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0056 0.0417 0.0987
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0088 0.0088
Toxoplasma gondii hypothetical protein 0.0018 0.0082 0.0073
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0154 0.0152
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0056 0.0417 0.0417
Echinococcus multilocularis MATE efflux family protein subfamily 0.0012 0.0026 0.0026
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Loa Loa (eye worm) hypothetical protein 0.0048 0.0351 0.0351
Brugia malayi DIX domain containing protein 0.0018 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Echinococcus granulosus caspase 3 0.0146 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0054 0.04 0.04
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0134 0.0123
Schistosoma mansoni hypothetical protein 0.0098 0.0788 0.0786
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0109 0.0107
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0036 0.0036
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0339 0.033
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0047 0.0336 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0056 0.0417 0.0417
Schistosoma mansoni hypothetical protein 0.0053 0.0394 0.0392
Brugia malayi CHD4 protein 0.0013 0.0033 0.0033
Brugia malayi conserved hypotetical protein 0.0026 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Trypanosoma cruzi metacaspase 5, putative 0.0089 0.0712 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.014 0.0175
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0088 0.0087
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0391 0.0391
Echinococcus multilocularis paired box protein pax 6 0.0009 0.0002 0.0001
Brugia malayi RasGEF domain containing protein 0.0013 0.0036 0.0036
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0056 0.0056
Echinococcus granulosus single minded 2 0.0112 0.0912 0.0911
Trypanosoma cruzi hypothetical protein, conserved 0.0137 0.114 0.1515
Schistosoma mansoni multidrug resistance protein 0.0012 0.0026 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.2059 0.2059
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.001 0.001
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Onchocerca volvulus Protein cycle homolog 0.0018 0.0079 0.0183
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Schistosoma mansoni nuclear receptor 0.0026 0.0154 0.0152
Echinococcus multilocularis kelch ECH associated protein 1 0.0097 0.0785 0.0784
Schistosoma mansoni chromobox protein 0.0068 0.0522 0.0521
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0056 0.0417 0.0415
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0056 0.0417 0.0417
Leishmania major metacaspase, putative 0.0089 0.0712 0.0942
Echinococcus granulosus geminin 0.0506 0.4422 0.4422
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0168 0.0166
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0339 0.0338
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0013 0.0036 0.0161
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.0105
Brugia malayi Matrixin family protein 0.0051 0.0377 0.0377
Echinococcus granulosus snurportin 1 0.0303 0.2614 0.2613
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.001 0.001 0.0019
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0109 0.0109
Brugia malayi hypothetical protein 0.0706 0.6203 0.6203
Schistosoma mansoni cpg binding protein 0.0031 0.0198 0.0196
Echinococcus multilocularis thyroid hormone receptor alpha 0.0056 0.0417 0.0416
Entamoeba histolytica Ran family GTPase 0.0021 0.0105 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Echinococcus granulosus ecdysone induced protein 78C 0.0056 0.0417 0.0416
Brugia malayi ecdysteroid receptor 0.0056 0.0417 0.0417
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.001 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0056 0.0417 0.0417
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0047 0.0336 0.2038
Schistosoma mansoni single-minded 0.0158 0.1329 0.1328
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0018 0.0008
Schistosoma mansoni chromobox protein 0.0011 0.0018 0.0017
Echinococcus multilocularis kelch ECH associated protein 1 0.0097 0.0785 0.0784
Schistosoma mansoni smad1 5 8 and 0.0016 0.0065 0.0064
Brugia malayi Globin family protein 0.0017 0.0071 0.0071
Loa Loa (eye worm) globin family protein 0.0017 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Trypanosoma brucei metacaspase MCA3 0.0089 0.0712 0.0942
Loa Loa (eye worm) matrixin family protein 0.0051 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0165 0.1391 0.1391
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.0342 0.0445
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0154 0.0362
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0339 0.0338
Schistosoma mansoni steroid hormone receptor ad4bp 0.0056 0.0417 0.0415
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0371 0.0485
Entamoeba histolytica hypothetical protein 0.0023 0.0124 0.0714
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0065 0.0065
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0151 0.015
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0339 0.0338
Mycobacterium ulcerans monooxygenase 0.0017 0.0071 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.1782 0.2376
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0243 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Onchocerca volvulus 0.003 0.0184 0.0434
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.015 0.0155
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0036 0.0036
Leishmania major DNA polymerase kappa, putative 0.0019 0.0088 0.0105
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0012 0.003 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0243 0.0313
Trichomonas vaginalis multidrug resistance pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.001 0.001 0.001
Echinococcus multilocularis aryl hydrocarbon receptor 0.0065 0.0496 0.0495
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0283 0.1705
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0154 0.0153
Onchocerca volvulus 0.0054 0.04 0.0947
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0154 0.0153
Brugia malayi hypothetical protein 0.0083 0.0658 0.0658
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0082 0.0081
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0258 0.0334
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0012 0.0026 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0478 0.0476
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0243 0.0312
Brugia malayi hypothetical protein 0.0017 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0018 0.0082 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Schistosoma mansoni coup transcription factor 0.0056 0.0417 0.0415
Brugia malayi DKFZp564C0469 protein 0.001 0.001 0.001
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0243 0.1454
Loa Loa (eye worm) hypothetical protein 0.0025 0.0142 0.0142
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0182 0.0182
Schistosoma mansoni hypothetical protein 0.0107 0.0875 0.0874
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0105 0.06
Loa Loa (eye worm) hypothetical protein 0.0026 0.0151 0.0151
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0336 0.0438
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0018 0.0008
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0082 0.0081
Giardia lamblia Na+ driven multidrug efflux pump 0.0012 0.0026 0.0109
Brugia malayi hypoxia-induced factor 1 0.0466 0.4071 0.4071
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Trypanosoma brucei MATE efflux family protein, putative 0.0137 0.114 0.1515
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0417 0.0417
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.3669 0.3669
Echinococcus multilocularis transfer RNA-Lys 0.0112 0.0912 0.0911
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0875 0.0875
Trichomonas vaginalis CAMK family protein kinase 0.019 0.1612 1
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0047 0.0336 0.2038
Schistosoma mansoni hypothetical protein 0.0033 0.0214 0.0213
Brugia malayi hypothetical protein 0.003 0.0182 0.0182
Echinococcus granulosus 3'partial|multidrug and toxin extrusion protein 1 0.0012 0.0026 0.0026
Brugia malayi hypothetical protein 0.003 0.0182 0.0182
Echinococcus granulosus neuroligin 0.0028 0.0168 0.0167
Loa Loa (eye worm) intermediate filament protein 0.0054 0.04 0.04
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.019 0.1612 0.1611
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0036 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.04 0.04
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0209 0.0388
Trypanosoma cruzi hypothetical protein 0.0013 0.0036 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Brugia malayi MH2 domain containing protein 0.0016 0.0065 0.0065
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0088 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0026 0.0104
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0134 0.0242
Brugia malayi hypothetical protein 0.0531 0.4647 0.4647
Echinococcus multilocularis dna polymerase eta 0.0044 0.0311 0.0311
Schistosoma mansoni zinc finger protein 0.0026 0.0154 0.0152
Entamoeba histolytica hypothetical protein 0.0107 0.0875 0.5402
Loa Loa (eye worm) vab-3 0.0009 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0088 0.0034
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.001 0.0001
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0587 0.5141 1
Onchocerca volvulus 0.0017 0.0071 0.0166
Echinococcus multilocularis cpg binding protein 0.0031 0.0198 0.0197
Echinococcus granulosus son of sevenless 1 0.0013 0.0036 0.0035
Brugia malayi Carboxylesterase family protein 0.0028 0.0168 0.0168
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0018 0.0017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0351 0.0351
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0311 0.0405
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0531 0.4647 0.4647
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0168 0.0191
Brugia malayi Carboxylesterase family protein 0.0028 0.0168 0.0168
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0183 0.0183
Loa Loa (eye worm) carboxylesterase 0.0028 0.0168 0.0168
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0089 0.0712 0.0711
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Echinococcus granulosus smad 0.0016 0.0065 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0105 0.0104
Mycobacterium tuberculosis Conserved protein 0.0024 0.0134 0.0123
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0033 0.0033
Plasmodium falciparum metacaspase 1 0.0089 0.0712 0.0703
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0154
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0036 0.0161
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0013 0.0036 0.0035
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0339 0.033
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0082 0.0081
Echinococcus granulosus caspase 0.0235 0.2015 0.2015
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0088 0.0106
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.0342 0.0445
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0028 0.0168 0.0167
Leishmania major DNA topoisomerase IB, large subunit 0.0848 0.7467 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0088 0.0491
Brugia malayi paired box pox-meso protein 0.0009 0.0002 0.0002
Echinococcus multilocularis paired box protein pax 6 0.0009 0.0002 0.0001
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0258 0.0258
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.019 0.1612 0.2149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0078 0.0425
Brugia malayi Steroid receptor seven-up type 2 0.0056 0.0417 0.0417
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0134 0.0166
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0154 0.0362
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0168
Leishmania major importin beta-1 subunit, putative 0.0023 0.0124 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.0052
Schistosoma mansoni hypothetical protein 0.003 0.0188 0.0186
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0088 0.0087
Trichomonas vaginalis Na+ driven multidrug efflux pump, putative 0.0012 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0056 0.0417 0.0417
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0079 0.0079
Echinococcus granulosus dna polymerase eta 0.0044 0.0311 0.0311
Loa Loa (eye worm) hypoxia-induced factor 1 0.0466 0.4071 0.4071
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0182
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0082 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0712 0.4384
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0013 0.0036 0.0035
Schistosoma mansoni thyroid hormone receptor 0.0056 0.0417 0.0415
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0182 0.0181
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0089 0.0712 0.0703
Brugia malayi Matrixin family protein 0.0021 0.0109 0.0109
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0026 0.0022
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0082 0.0081
Brugia malayi Importin beta-1 subunit 0.0028 0.0172 0.0172
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0056 0.0417 0.0415
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0051 0.0371 0.0371
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0144 0.1201 0.1201
Loa Loa (eye worm) hypothetical protein 0.0372 0.3229 0.3229
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0336 0.2038

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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