Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | farnesyltransferase beta subunit | 0.003 | 0.0119 | 0.1605 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0 | 0.0002 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.021 | 0.3111 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0037 | 0.018 | 0.0157 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trichomonas vaginalis | protein farnesyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0037 | 0.018 | 0.2608 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0092 | 0.0623 | 0.2439 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.0526 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0 | 0.0002 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0378 | 0.1478 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054 | 0.031 | 0.1214 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0004 | 0.0016 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.3111 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0119 | 0.1605 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0004 | 0.0016 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.021 | 0.3111 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0118 | 0.0831 | 0.5537 |
Echinococcus multilocularis | Rab geranylgeranyltransferase, beta subunit | 0.003 | 0.0119 | 0.0468 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.0041 | 0.021 | 0.3111 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0185 | 0.1052 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0159 | 0.1165 | 0.661 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.003 | 0.0119 | 0.1605 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Plasmodium falciparum | thioredoxin reductase | 0.0032 | 0.0134 | 0.0974 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0159 | 0.1165 | 0.661 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.003 | 0.0119 | 0.0468 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0 | 0.0002 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0023 | 0.0003 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0 | 0.0002 |
Schistosoma mansoni | geranylgeranyl transferase type II beta subunit | 0.003 | 0.0119 | 0.0468 |
Trypanosoma brucei | unspecified product | 0.0026 | 0.0085 | 0.1033 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0023 | 0.0066 | 0.0373 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0161 | 0.0944 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0032 | 0.0134 | 0.0111 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0032 | 0.0134 | 0.0111 |
Entamoeba histolytica | geranylgeranyl transferase beta subunit | 0.0198 | 0.1482 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.021 | 0.158 | 0.2186 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0032 | 0.0134 | 0.0411 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.021 | 0.3111 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.003 | 0.0119 | 0.1605 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0 | 0.0003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0092 | 0.0623 | 0.3534 |
Plasmodium vivax | geranylgeranyl transferase type2 beta subunit, putative | 0.003 | 0.0119 | 0.0843 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0378 | 0.1478 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0159 | 0.1165 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0234 | 0.1771 | 0.2453 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0161 | 0.0629 |
Trichomonas vaginalis | MYB, putative | 0.0018 | 0.0024 | 0.0005 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0023 | 0.0132 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0041 | 0.021 | 0.3111 |
Plasmodium falciparum | thioredoxin reductase | 0.0092 | 0.0623 | 0.5251 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0378 | 0.1478 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0037 | 0.018 | 0.1074 |
Toxoplasma gondii | Rab geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.0356 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0004 | 0.0023 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.0526 |
Brugia malayi | MH2 domain containing protein | 0.0233 | 0.1763 | 1 |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.0896 | 0.7146 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0032 | 0.0134 | 0.1854 |
Echinococcus granulosus | geminin | 0.033 | 0.2554 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0159 | 0.1165 | 0.7828 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.003 | 0.0119 | 0.0135 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0004 | 0.0023 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0085 | 0.1033 |
Leishmania major | trypanothione reductase | 0.0092 | 0.0623 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0037 | 0.018 | 0.1019 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0037 | 0.018 | 0.1019 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0271 | 0.1535 |
Mycobacterium ulcerans | 3-phosphoshikimate 1-carboxyvinyltransferase | 0.0352 | 0.273 | 0.2713 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0 | 0.0003 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.1854 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0004 | 0.0016 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0 | 0.0002 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0032 | 0.0134 | 0.0974 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0037 | 0.018 | 0.1074 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0023 | 0.0132 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0032 | 0.0134 | 0.0763 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0378 | 0.2142 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0159 | 0.1165 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0119 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0233 | 0.1321 |
Echinococcus granulosus | dna polymerase eta | 0.0062 | 0.038 | 0.1489 |
Leishmania major | geranylgeranyltransferase, putative | 0.003 | 0.0119 | 0.1605 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0023 | 0.0091 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0023 | 0.0066 | 0.0373 |
Echinococcus multilocularis | geminin | 0.033 | 0.2554 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0159 | 0.1165 | 0.7828 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0004 | 0.0023 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0378 | 0.2142 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0038 | 0.0185 | 0.0726 |
Plasmodium falciparum | glutathione reductase | 0.0092 | 0.0623 | 0.5251 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0161 | 0.0911 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0092 | 0.0623 | 0.0842 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.3111 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.004 | 0.0197 | 0.1116 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.003 | 0.0119 | 0.1605 |
Toxoplasma gondii | hypothetical protein | 0.0041 | 0.021 | 0.0689 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0037 | 0.018 | 0.022 |
Plasmodium vivax | geranylgeranyltransferase, putative | 0.003 | 0.0119 | 0.0843 |
Onchocerca volvulus | 0.0041 | 0.021 | 0.5 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054 | 0.031 | 0.1214 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0023 | 0.0003 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.1854 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0159 | 0.1165 | 0.7828 |
Schistosoma mansoni | DNA polymerase eta | 0.0062 | 0.038 | 0.1489 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0234 | 0.1771 | 0.2453 |
Plasmodium falciparum | geranylgeranyl transferase type2 beta subunit, putative | 0.003 | 0.0119 | 0.0843 |
Echinococcus multilocularis | dna polymerase eta | 0.0062 | 0.038 | 0.1489 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0004 | 0.0023 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.003 | 0.0119 | 0.0678 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1248 | 1 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0092 | 0.0623 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0032 | 0.0134 | 0.1854 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0054 | 0.031 | 0.1214 |
Leishmania major | protein farnesyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.3111 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.021 | 0.158 | 0.2186 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0004 | 0.0016 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.3111 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.0526 |
Schistosoma mansoni | hypothetical protein | 0.033 | 0.2554 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0378 | 0.2142 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1165 | 0.661 |
Brugia malayi | Smad1 | 0.0016 | 0.0004 | 0.0023 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0004 | 0.0023 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.021 | 0.158 | 0.2186 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.003 | 0.0119 | 0.0843 |
Trypanosoma brucei | unspecified product | 0.0037 | 0.018 | 0.2608 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0023 | 0.0091 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.003 | 0.0119 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0 | 0.0003 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.003 | 0.0119 | 0.0468 |
Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.0041 | 0.021 | 0.0821 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0161 | 0.0629 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0004 | 0.0016 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0037 | 0.018 | 0.2608 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0378 | 0.2142 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0004 | 0.0016 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0092 | 0.0623 | 0.2439 |
Trypanosoma brucei | lanosterol synthase | 0.003 | 0.0119 | 0.1605 |
Trypanosoma brucei | unspecified product | 0.0026 | 0.0085 | 0.1033 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0 | 0.0002 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0032 | 0.0134 | 0.0974 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.003 | 0.0119 | 0.0356 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0198 | 0.1482 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0032 | 0.0134 | 0.0111 |
Plasmodium falciparum | geranylgeranyl transferase type-2 subunit alpha, putative | 0.0041 | 0.021 | 0.1634 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.0198 | 0.1482 | 0.5803 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0146 | 0.0826 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0004 | 0.0016 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0037 | 0.018 | 0.0157 |
Entamoeba histolytica | Rab geranylgeranyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.1281 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0 | 0.0002 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0032 | 0.0134 | 0.0111 |
Schistosoma mansoni | smad | 0.0016 | 0.0004 | 0.0016 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0843 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trichomonas vaginalis | protein farnesyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.0041 | 0.021 | 0.0821 |
Entamoeba histolytica | Rab geranylgeranyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1248 | 1 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0032 | 0.0134 | 0.1854 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.003 | 0.0119 | 0.0356 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0233 | 0.1763 | 1 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0198 | 0.1482 | 0.8408 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0041 | 0.021 | 0.119 |
Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.0041 | 0.021 | 0.0821 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0233 | 0.1763 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0004 | 0.0023 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0032 | 0.0134 | 0.0974 |
Echinococcus multilocularis | smad | 0.0016 | 0.0004 | 0.0016 |
Brugia malayi | Protein kinase c protein 2 | 0.0045 | 0.0244 | 0.1385 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0041 | 0.021 | 0.1634 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0271 | 0.1535 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0004 | 0.0016 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0037 | 0.018 | 0.0703 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0085 | 0.1033 |
Trypanosoma cruzi | geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.1605 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.021 | 0.158 | 0.2186 |
Giardia lamblia | DINP protein human, muc B family | 0.0037 | 0.018 | 0.1369 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.0198 | 0.1482 | 0.5803 |
Schistosoma mansoni | hypothetical protein | 0.033 | 0.2554 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0037 | 0.018 | 0.0703 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0032 | 0.0134 | 0.0765 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0378 | 0.2142 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0032 | 0.0134 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0 | 0.0002 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0 | 0.0002 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0234 | 0.1771 | 0.0342 |
Toxoplasma gondii | thioredoxin reductase | 0.0092 | 0.0623 | 0.2216 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.003 | 0.0119 | 0.1605 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0378 | 0.1478 |
Chlamydia trachomatis | phosphoshikimate 1-carboxyl vinyltransferase | 0.0352 | 0.273 | 0.2631 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0037 | 0.018 | 0.022 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0032 | 0.0134 | 0.0111 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0032 | 0.0134 | 0.0974 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0036 | 0.0171 | 0.0544 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0004 | 0.0023 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0271 | 0.1535 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1248 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0161 | 0.0944 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0062 | 0.038 | 0.5956 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0146 | 0.057 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0161 | 0.0629 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0119 | 0.0678 |
Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.1634 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0119 | 0.0678 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0159 | 0.1165 | 1 |
Echinococcus granulosus | geranylgeranyl transferase type I beta subunit | 0.0198 | 0.1482 | 0.5803 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0038 | 0.0185 | 0.0726 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0023 | 0.0003 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0062 | 0.038 | 0.5956 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0092 | 0.0623 | 0.5251 |
Leishmania major | DNA polymerase eta, putative | 0.0062 | 0.038 | 0.5956 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0023 | 0.0091 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0378 | 0.1478 |
Toxoplasma gondii | Myb family DNA-binding domain-containing protein | 0.0018 | 0.0024 | 0.0001 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Echinococcus granulosus | dna polymerase kappa | 0.0037 | 0.018 | 0.0703 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0041 | 0.021 | 0.119 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0198 | 0.1482 | 0.8408 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0004 | 0.0016 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0038 | 0.0185 | 0.0726 |
Echinococcus multilocularis | geranylgeranyl transferase type I beta subunit | 0.0198 | 0.1482 | 0.5803 |
Brugia malayi | Thioredoxin reductase | 0.0092 | 0.0623 | 0.3534 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0004 | 0.0016 |
Brugia malayi | Probable protein farnesyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0678 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0378 | 0.1478 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0159 | 0.1165 | 0.4562 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0079 | 0.0514 | 0.2012 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0048 | 0.0262 | 0.1028 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0085 | 0.1033 |
Trypanosoma brucei | geranylgeranyl transferase type II beta subunit, putative | 0.003 | 0.0119 | 0.1605 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0 | 0.0002 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0054 | 0.031 | 0.1214 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0032 | 0.0134 | 0.0974 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.0896 | 0.7146 | 1 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0159 | 0.1165 | 0.7828 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0037 | 0.018 | 0.0703 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.003 | 0.0119 | 0.0843 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0159 | 0.1165 | 0.4562 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.003 | 0.0119 | 0.0678 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0004 | 0.0016 |
Echinococcus granulosus | protein kinase C gamma type | 0.0048 | 0.0262 | 0.1028 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0378 | 0.1478 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0041 | 0.021 | 0.1281 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0037 | 0.018 | 0.2608 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0032 | 0.0134 | 0.0765 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0146 | 0.0826 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0378 | 0.2142 |
Echinococcus multilocularis | dna polymerase kappa | 0.0037 | 0.018 | 0.0703 |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.003 | 0.0119 | 0.0468 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0036 | 0.0171 | 0.2457 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.0018 | 0.0024 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0161 | 0.0629 |
Plasmodium vivax | glutathione reductase, putative | 0.0092 | 0.0623 | 0.5251 |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0037 | 0.018 | 0.1074 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0041 | 0.021 | 0.3111 |
Plasmodium falciparum | glutathione reductase | 0.0032 | 0.0134 | 0.0974 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0234 | 0.1771 | 0.2453 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0161 | 0.0944 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0032 | 0.0134 | 0.0156 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0271 | 0.1535 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.0018 | 0.0024 | 0.0005 |
Loa Loa (eye worm) | glutathione reductase | 0.0092 | 0.0623 | 0.3534 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0023 | 0.0091 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.021 | 0.158 | 0.2186 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0352 | 0.273 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0032 | 0.0134 | 0.1854 |
Leishmania major | DNA polymerase eta, putative | 0.0036 | 0.0171 | 0.2457 |
Echinococcus granulosus | smad | 0.0016 | 0.0004 | 0.0016 |
Toxoplasma gondii | hypothetical protein | 0.0118 | 0.0831 | 0.2984 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0037 | 0.018 | 0.2608 |
Giardia lamblia | Prenyltransferase | 0.003 | 0.0119 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.038 | 0.2158 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0037 | 0.018 | 0.2608 |
Treponema pallidum | NADH oxidase | 0.0032 | 0.0134 | 0.0111 |
Brugia malayi | glutathione reductase | 0.0092 | 0.0623 | 0.3534 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0062 | 0.038 | 0.2158 |
Mycobacterium leprae | probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS | 0.0352 | 0.273 | 0.2065 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.0134 | 0.1854 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0161 | 0.0944 |
Giardia lamblia | Myb 1-like protein | 0.0018 | 0.0024 | 0.0003 |
Mycobacterium tuberculosis | Probable reductase | 0.021 | 0.158 | 0.2186 |
Trypanosoma brucei | trypanothione reductase | 0.0092 | 0.0623 | 1 |
Plasmodium falciparum | geranylgeranyltransferase, putative | 0.003 | 0.0119 | 0.0843 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0032 | 0.0134 | 0.1854 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.003 | 0.0119 | 0.0662 |
Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.0041 | 0.021 | 0.0821 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0159 | 0.1165 | 0.4562 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.