Detailed information for compound 83787

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 374.517 | Formula: C22H34N2O3
  • H donors: 1 H acceptors: 2 LogP: 3.19 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCOC(=O)CCc1cc(CN2CCCC2)c(c(c1)CN1CCCC1)O
  • InChi: 1S/C22H34N2O3/c1-2-13-27-21(25)8-7-18-14-19(16-23-9-3-4-10-23)22(26)20(15-18)17-24-11-5-6-12-24/h14-15,26H,2-13,16-17H2,1H3
  • InChiKey: UEWLMZBRXDSRDP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0044 0.0085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0025 0.0033
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0011
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0014 0.0052 0.0277
Schistosoma mansoni polypyrimidine tract binding protein 0.0012 0.0029 0.0027
Brugia malayi Flap endonuclease-1 0.0031 0.0237 0.0777
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.014 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0259 0.0623
Leishmania major arginine N-methyltransferase, type I 0.0029 0.0222 0.0665
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0375 0.1229
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.014 0.0328
Brugia malayi Cytochrome P450 family protein 0.0022 0.0138 0.0452
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.014 0.0133
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0139 0.0132
Plasmodium vivax polypyrimidine tract binding protein, putative 0.0012 0.0029 0.0295
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0375 0.0368
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0025 0.0017
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0052 0.0481 0.302
Loa Loa (eye worm) hypothetical protein 0.0027 0.0198 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0128 0.0276
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0375 0.0368
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0132 0.013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0343 0.3799 1
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0132 0.0351
Schistosoma mansoni kinase 0.0056 0.0531 0.0529
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0277
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0025 0.0017
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.003 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0139 0.0186
Loa Loa (eye worm) RecQ helicase 0.0053 0.0495 0.0661
Loa Loa (eye worm) fli-1 protein 0.0219 0.2382 0.3177
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0025 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0271 0.2983 0.2977
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0277
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus granulosus g protein coupled receptor 0.0012 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.001 0.0008 0.0006
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0118 0.0158
Schistosoma mansoni gliotactin 0.0046 0.0412 0.041
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0025 0.0081
Brugia malayi CAAX amino terminal protease family protein 0.0091 0.0928 0.304
Loa Loa (eye worm) hypothetical protein 0.0153 0.1633 0.2177
Schistosoma mansoni dep domain containing protein 0.001 0.0008 0.0005
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0052 0.0481 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0375 0.1229
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0423 0.0416
Entamoeba histolytica deoxycytidyl transferase, putative 0.0054 0.0505 0.1302
Echinococcus granulosus Chromo domain 0.0013 0.0041 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0451 0.1132
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0079 0.0426
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0081 0.0074
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.008 0.0462
Schistosoma mansoni smad1 5 8 and 0.0018 0.009 0.0088
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0025 0.0022
Brugia malayi MH2 domain containing protein 0.0259 0.284 0.9304
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0279 0.4538
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Onchocerca volvulus 0.0046 0.0412 0.1404
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0025 0.0022
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0099 0.0249
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0194
Schistosoma mansoni histamine h1 receptor 0.0012 0.0025 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0226 0.0636
Echinococcus granulosus caspase 0.0137 0.1454 0.1447
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0237 0.071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.1395 0.1393
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Brugia malayi G-protein coupled receptor 0.0012 0.0025 0.0081
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0118 0.0111
Echinococcus multilocularis apoptotic protease activating factor 1 0.0048 0.044 0.0433
Echinococcus granulosus methyltransferase protein 5 0.0029 0.0222 0.0215
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0041 0.0039
Schistosoma mansoni flap endonuclease-1 0.0028 0.0204 0.0202
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0025 0.0022
Treponema pallidum DNA ligase (lig) 0.0021 0.0132 0.0306
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0423 0.1088
Brugia malayi kap beta 3 protein 0.0012 0.0024 0.0077
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0099 0.0096
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0054 0.0505 0.0498
Echinococcus granulosus nAChR subunit 0.0012 0.003 0.0023
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0008 0.0006
Brugia malayi N-terminal motif family protein 0.0212 0.2304 0.7548
Brugia malayi jmjC domain containing protein 0.0018 0.0099 0.0323
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0041 0.0047
Trypanosoma brucei metacaspase MCA3 0.0052 0.0481 0.1389
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0041 0.0079
Loa Loa (eye worm) hypothetical protein 0.0018 0.009 0.012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.037 0.1073
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.001
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0212 0.2304 0.7896
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0041 0.0308
Plasmodium falciparum protein arginine N-methyltransferase 1 0.004 0.0339 0.5463
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Schistosoma mansoni jun-related protein 0.008 0.0802 0.08
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0375 0.05
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0116 0.0245
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0343 0.3799 1
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0106 0.0346
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0279 0.0797
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0099 0.0581
Schistosoma mansoni hypothetical protein 0.0367 0.4078 0.4076
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0375 0.1229
Schistosoma mansoni survival motor neuron protein 0.0057 0.0534 0.0532
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0099 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0375 0.1229
Leishmania major DNA polymerase eta, putative 0.0054 0.0505 0.1518
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0375 0.0368
Onchocerca volvulus 0.0077 0.0771 0.2637
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0008 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0202 0.0473
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.008 0.0171
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0226 0.3502
Mycobacterium ulcerans hypothetical protein 0.0158 0.1693 0.9411
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0099 0.0091
Plasmodium falciparum flap endonuclease 1 0.0031 0.0237 0.3695
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.001
Entamoeba histolytica hypothetical protein 0.006 0.0578 0.1495
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.003 0.0099
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0602 0.1757
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.003 0.0099
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0271 0.2983 0.2981
Loa Loa (eye worm) hypothetical protein 0.0057 0.0543 0.0724
Schistosoma mansoni DNA polymerase eta 0.0054 0.0505 0.0503
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Echinococcus granulosus g protein coupled receptor 0.0012 0.0025 0.0017
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0029 0.0222 0.0625
Leishmania major metacaspase, putative 0.0052 0.0481 0.1445
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi CXXC zinc finger family protein 0.0062 0.0599 0.1962
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0041 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0194
Echinococcus multilocularis protein patched 0.0042 0.0368 0.0361
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0412 0.1028
Schistosoma mansoni caspase-7 (C14 family) 0.01 0.1032 0.103
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0118 0.0387
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0375 0.0368
Brugia malayi hypothetical protein 0.002 0.0118 0.0387
Leishmania major hypothetical protein, conserved 0.0012 0.0024 0.0065
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0423 0.0416
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0158 0.0866
Plasmodium falciparum metacaspase 1 0.0052 0.0481 0.7907
Schistosoma mansoni inositol monophosphatase 0.008 0.0802 0.08
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Loa Loa (eye worm) LGC-31 protein 0.0012 0.003 0.004
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0118 0.0111
Schistosoma mansoni biogenic amine receptor 0.0012 0.0025 0.0022
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0413 0.0406
Trypanosoma cruzi DNA polymerase kappa, putative 0.0112 0.1162 0.3474
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0041 0.0136
Echinococcus multilocularis caspase 0.0137 0.1454 0.1447
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.1005 0.0999
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0514 0.13
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0413 0.1204
Brugia malayi hypothetical protein 0.003 0.0226 0.074
Plasmodium vivax JmjC domain containing protein 0.0018 0.0099 0.1475
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.009 0.0082
Schistosoma mansoni hypothetical protein 0.0153 0.1633 0.1631
Onchocerca volvulus 0.0012 0.0025 0.0077
Echinococcus granulosus transportin 1 0.0012 0.0024 0.0016
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0411 0.0549
Brugia malayi sulfakinin receptor protein 0.0012 0.0025 0.0081
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Echinococcus granulosus intermediate filament protein 0.0058 0.0555 0.0548
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0167 0.1799 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Onchocerca volvulus 0.0012 0.003 0.0096
Echinococcus multilocularis dna polymerase kappa 0.0112 0.1162 0.1155
Brugia malayi jmjC domain containing protein 0.0018 0.0099 0.0323
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0008 0.0011
Echinococcus multilocularis caspase 3 0.0085 0.0862 0.0855
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0375 0.05
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0118 0.0111
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0091 0.0928 0.0926
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.014 0.0376
Echinococcus multilocularis carboxylesterase 5A 0.0271 0.2983 0.2977
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0736 0.0734
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0099 0.0249
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0008 0.001
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0118 0.0111
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0279 0.0372
Schistosoma mansoni DNA helicase recq5 0.0022 0.0139 0.0137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0079 0.0426
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Entamoeba histolytica CAAX prenyl protease family 0.0091 0.0928 0.242
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0132 0.0433
Brugia malayi MH1 domain containing protein 0.0018 0.009 0.0294
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0025 0.0033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0423 0.1215
Loa Loa (eye worm) DR-78 0.002 0.0118 0.0158
Echinococcus multilocularis small conductance calcium activated potassium 0.0153 0.1633 0.1626
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Schistosoma mansoni ran 0.0046 0.0413 0.0411
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.003 0.0023
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0148 0.1574 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0279 0.0913
Schistosoma mansoni neuropeptide receptor 0.0012 0.0025 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0111 0.1153 0.1146
Schistosoma mansoni hypothetical protein 0.0112 0.1167 0.1165
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.014 0.2021
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.004 0.0032
Plasmodium falciparum DNA repair protein REV1, putative 0.0017 0.008 0.0975
Schistosoma mansoni hypothetical protein 0.0667 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Schistosoma mansoni hypothetical protein 0.0048 0.044 0.0438
Echinococcus granulosus Chromobox protein 3 0.0013 0.0041 0.0034
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.1693 0.9411
Onchocerca volvulus 0.0012 0.0025 0.0077
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Brugia malayi Melatonin receptor type 1A 0.0012 0.0025 0.0081
Loa Loa (eye worm) hypothetical protein 0.0096 0.0981 0.1309
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0158 0.0866
Schistosoma mansoni chromobox protein 0.0082 0.0821 0.0819
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Trichomonas vaginalis ran, putative 0.0046 0.0413 0.1032
Loa Loa (eye worm) hypothetical protein 0.0149 0.1583 0.2111
Trypanosoma brucei DNA polymerase kappa, putative 0.0068 0.0668 0.1958
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0025 0.0077
Toxoplasma gondii CAAX amino terminal protease family protein 0.0019 0.0103 0.061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0081 0.0108
Brugia malayi Nuclear hormone receptor E75 0.002 0.0118 0.0387
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.2818 0.3758
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0099 0.0132
Brugia malayi hypothetical protein 0.002 0.0118 0.0387
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0375 0.0373
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0044 0.0085
Echinococcus multilocularis Regulator of differentiation 1 0.0012 0.0029 0.0021
Onchocerca volvulus 0.0048 0.044 0.1502
Onchocerca volvulus 0.0013 0.0041 0.0134
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0139 0.084
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0368 0.0491
Onchocerca volvulus 0.0118 0.124 0.4246
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.003 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Leishmania major importin beta-1 subunit, putative 0.0051 0.0467 0.1403
Loa Loa (eye worm) helicase 0.0013 0.0041 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0118 0.0398
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0237 0.0596
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Onchocerca volvulus 0.0012 0.0025 0.0077
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0025 0.0017
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0025 0.0017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.004 0.0032
Trichomonas vaginalis DNA helicase recq1, putative 0.0053 0.0495 0.125
Schistosoma mansoni myosin xvIII 0.0012 0.0025 0.0022
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0132 0.0125
Echinococcus multilocularis muscleblind protein 0.0149 0.1583 0.1577
Loa Loa (eye worm) hypothetical protein 0.0149 0.1583 0.2111
Echinococcus granulosus caspase 8 0.0052 0.0481 0.0473
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0368 0.0361
Schistosoma mansoni microtubule-associated protein tau 0.081 0.9121 0.9121
Brugia malayi intermediate filament protein 0.0058 0.0555 0.182
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.009 0.1144
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0412 0.041
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0146 0.0478
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.008 0.0193
Plasmodium vivax metacaspase 1, putative 0.0052 0.0481 0.7949
Schistosoma mansoni smad 0.0018 0.009 0.0088
Brugia malayi nuclear receptor NHR-88 0.0043 0.0375 0.1229
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0167 0.1799 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0118 0.0111
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0167 0.1799 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0736 0.0982
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0025 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0132 0.0288
Mycobacterium tuberculosis Probable integral membrane protein 0.0019 0.0103 0.0563
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0139 0.0132
Schistosoma mansoni neuropeptide receptor 0.0012 0.0025 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0025 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0375 0.0373
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Onchocerca volvulus 0.0012 0.0025 0.0077
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0279 0.0797
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0423 0.0421
Schistosoma mansoni netrin receptor unc5 0.0017 0.0081 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0279 0.1543
Brugia malayi hypothetical protein 0.0023 0.0146 0.0478
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.008 0.0171
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0028 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0158 0.0866
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0029 0.0222 0.0625
Echinococcus multilocularis sex peptide receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0025 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0158 0.0866
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0025 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0025 0.0022
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0412 0.1028
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0237 0.3824
Schistosoma mansoni biogenic amine (5HT) receptor 0.0134 0.142 0.1418
Loa Loa (eye worm) hypothetical protein 0.006 0.0578 0.0771
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0025 0.0081
Brugia malayi jmjC domain containing protein 0.0069 0.0676 0.2213
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0158 0.0866
Brugia malayi bZIP transcription factor family protein 0.0099 0.1012 0.3316
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.0802 0.2061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.0802 0.5072
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0036 0.0299 0.4871
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.003 0.0023
Schistosoma mansoni ap endonuclease 0.0022 0.014 0.0138
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Brugia malayi hypothetical protein 0.0046 0.0412 0.1348
Echinococcus granulosus apoptotic protease activating factor 1 0.0048 0.044 0.0433
Schistosoma mansoni DNA helicase recq1 0.0022 0.0139 0.0137
Brugia malayi hypothetical protein 0.0277 0.3052 1
Brugia malayi neuropeptide F receptor 0.0012 0.0025 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0146 0.0478
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Trichomonas vaginalis hypothetical protein 0.0013 0.0041 0.0047
Echinococcus multilocularis dna polymerase eta 0.0054 0.0505 0.0498
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0375 0.0368
Onchocerca volvulus 0.0012 0.003 0.0096
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0026 0.0006
Schistosoma mansoni caspase-7 (C14 family) 0.0137 0.1454 0.1452
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0025 0.0017
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0026 0.0186 0.0515
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0137 0.1454 0.1447
Onchocerca volvulus Serine\/threonine kinase homolog 0.0111 0.1153 0.3946
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0041 0.0079
Toxoplasma gondii RNA recognition motif-containing protein 0.0012 0.0029 0.0136
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0736 0.0734
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0082 0.0819 0.0812
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0118 0.0111
Brugia malayi RNA binding protein 0.0074 0.0736 0.2412
Trypanosoma cruzi metacaspase, putative 0.0052 0.0481 0.1408
Onchocerca volvulus 0.0012 0.003 0.0096
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.003 0.0023
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.003 0.0028
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0246 0.0806
Leishmania major GTP-binding protein, putative 0.0046 0.0413 0.1242
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.003 0.0099
Schistosoma mansoni tsg101-related 0.0068 0.0664 0.0662
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0375 0.0368
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0158 0.0517
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.151 0.4552
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0025 0.0017
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0368 0.0361
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Brugia malayi SET domain containing protein 0.0015 0.0057 0.0186
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0412 0.041
Echinococcus granulosus smad 0.0018 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0052 0.0481 0.0641
Schistosoma mansoni DNA polymerase IV / kappa 0.0017 0.008 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0112 0.1162 0.346
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0099 0.0132
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.003 0.0099
Schistosoma mansoni lamin 0.0058 0.0555 0.0553
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0132 0.0125
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.014 0.0123
Echinococcus granulosus g protein coupled receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0058 0.0555 0.0741
Echinococcus multilocularis chromobox protein 1 0.0082 0.0821 0.0814
Brugia malayi hypothetical protein 0.001 0.0008 0.0025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0158 0.0153
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0132 0.0288
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Brugia malayi Inositol-1 0.008 0.0802 0.2627
Echinococcus granulosus cpg binding protein 0.0066 0.0639 0.0632
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0091 0.0928 0.2764
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0412 0.0404
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.1023 0.1021
Plasmodium vivax protease, putative 0.0019 0.0103 0.1554
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0132 0.0351
Entamoeba histolytica hypothetical protein 0.0014 0.0044 0.0087
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0099 0.0091
Chlamydia trachomatis hypothetical protein 0.0019 0.0103 0.3187
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.003 0.004
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0132 0.0433
Schistosoma mansoni chromobox protein 0.0082 0.0821 0.0819
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0025 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0041 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.014 0.034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0375 0.05
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.0054 0.0505 0.0673
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0413 0.1204
Schistosoma mansoni neuropeptide receptor 0.0012 0.0025 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0044 0.0055
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0103 0.0242
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0412 0.0404
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0065 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0193
Brugia malayi hypothetical protein 0.001 0.0008 0.0025
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0118 0.0158
Leishmania major hypothetical protein, conserved 0.0018 0.0099 0.0291
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.009 0.012
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0099 0.0091
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0467 0.1174
Schistosoma mansoni biogenic amine receptor 0.0012 0.0025 0.0022
Mycobacterium ulcerans hypothetical protein 0.0019 0.0103 0.0563
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi Nuclear hormone receptor E75 0.002 0.0118 0.0387
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Brugia malayi CHD4 protein 0.0017 0.0082 0.0268
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0103 0.0563
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0079 0.0426
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0148 0.1574 0.1567
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Echinococcus multilocularis caspase 8 0.0052 0.0481 0.0473
Onchocerca volvulus 0.0015 0.0057 0.0188
Brugia malayi Importin beta-1 subunit 0.0063 0.0602 0.1971
Loa Loa (eye worm) hypothetical protein 0.01 0.1032 0.1376
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0103 0.0563
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Mycobacterium ulcerans DNA polymerase IV 0.0112 0.1162 0.6456
Schistosoma mansoni dishevelled 0.001 0.0008 0.0005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0375 0.1229
Echinococcus granulosus snurportin 1 0.0667 0.7498 0.7496
Schistosoma mansoni importin-beta 2 0.0012 0.0024 0.0021
Brugia malayi Globin family protein 0.001 0.0002 0.0007
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0279 0.1735
Brugia malayi Carboxylesterase family protein 0.0046 0.0412 0.1348
Loa Loa (eye worm) hypothetical protein 0.0063 0.0602 0.0802
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.003 0.0023
Echinococcus granulosus serotonin receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0074 0.0731 0.0975
Entamoeba histolytica hypothetical protein 0.0021 0.0132 0.0318
Loa Loa (eye worm) hypothetical protein 0.0018 0.009 0.012
Brugia malayi hypothetical protein 0.0021 0.0132 0.0433
Loa Loa (eye worm) hypothetical protein 0.0018 0.0099 0.0132
Echinococcus multilocularis acetylcholinesterase 0.0271 0.2983 0.2977
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0025 0.0017
Echinococcus granulosus chromobox protein 1 0.0082 0.0821 0.0814
Loa Loa (eye worm) hypothetical protein 0.0271 0.2983 0.3978
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.014 0.0309
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Onchocerca volvulus 0.0021 0.0132 0.0446
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0118 0.0116
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.2818 0.9231
Schistosoma mansoni terminal deoxycytidyl transferase 0.0054 0.0505 0.0503
Schistosoma mansoni hypothetical protein 0.0013 0.004 0.0038
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0025 0.0081
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0279 0.0913
Echinococcus granulosus flap endonuclease 1 0.0031 0.0237 0.023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0099 0.0091
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0716 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0368 0.0912
Brugia malayi steroid hormone receptor 0.0043 0.0375 0.1229
Schistosoma mansoni amine GPCR 0.0012 0.0025 0.0022
Brugia malayi Protein arginine N-methyltransferase 0.0029 0.0222 0.0729
Schistosoma mansoni hypothetical protein 0.0074 0.0731 0.0729
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0139 0.0456
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0025 0.0017
Entamoeba histolytica Ran family GTPase 0.0046 0.0413 0.1061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0375 0.0368
Echinococcus granulosus protein arginine methyltransferase 0.004 0.0339 0.0332
Loa Loa (eye worm) carboxylesterase 0.0271 0.2983 0.3978
Echinococcus multilocularis microtubule associated protein 2 0.081 0.9121 0.912
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus granulosus caspase 3 0.0085 0.0862 0.0855
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.003 0.0023
Trypanosoma cruzi metacaspase, putative 0.0052 0.0481 0.1408
Echinococcus granulosus nibrin 0.0021 0.0132 0.0125
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0375 0.0373
Schistosoma mansoni cpg binding protein 0.0066 0.0639 0.0637
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0082 0.0074
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0138 0.0184
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0194
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0025 0.0017
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0139 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Brugia malayi putative neuropeptide receptor 0.0012 0.0025 0.0081
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis musashi 0.0058 0.0555 0.0548
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Schistosoma mansoni hypothetical protein 0.0012 0.0025 0.0022
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.008 0.0193
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0277
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0112 0.1162 0.3016
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0237 0.1466
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0375 0.1229
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0874 0.0867
Schistosoma mansoni zinc finger protein 0.002 0.0118 0.0116
Brugia malayi hypothetical protein 0.0048 0.044 0.1441
Trypanosoma brucei DNA polymerase IV, putative 0.0097 0.0999 0.2964
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0008 0.0025
Onchocerca volvulus 0.0012 0.0025 0.0077
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0132 0.0288
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0375 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0514 0.13
Echinococcus multilocularis translational activator gcn1 0.0012 0.0024 0.0016
Onchocerca volvulus 0.0024 0.0158 0.0533
Schistosoma mansoni hypothetical protein 0.0012 0.0025 0.0022
Brugia malayi hypothetical protein 0.0023 0.0146 0.0478
Echinococcus multilocularis chromobox protein 1 0.0082 0.0821 0.0814
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Brugia malayi CHE-14 protein 0.0042 0.0368 0.1206
Echinococcus granulosus neuropeptide receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0082 0.0819 0.0812
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0025 0.0017
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Schistosoma mansoni hypothetical protein 0.0012 0.0025 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0737 0.2169
Schistosoma mansoni opsin-like receptor 0.0012 0.0025 0.0022
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.003 0.0099
Schistosoma mansoni hypothetical protein 0.0017 0.0081 0.0079
Echinococcus granulosus importin 5 0.0012 0.0024 0.0016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0202 0.0473
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.1175 0.1168
Echinococcus multilocularis protein dispatched 1 0.0048 0.0436 0.0428
Echinococcus multilocularis Smad4 0.0018 0.009 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0118 0.0111
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0025 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0041 0.0505
Brugia malayi Uncoordinated protein 44 0.0017 0.0081 0.0266
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0146 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0375 0.05
Entamoeba histolytica hypothetical protein 0.0014 0.0044 0.0087
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0132 0.0795
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.009 0.0088
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0016 0.0013
Plasmodium vivax transportin, putative 0.0012 0.0024 0.0204
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0279 0.0837
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0676 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0132 0.0288
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0802 0.2414
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.003 0.0023
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0025 0.0033
Echinococcus granulosus somatostatin receptor 0.0012 0.0025 0.0017
Brugia malayi tailless protein 0.002 0.0118 0.0387
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0226 0.3502
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.0413 0.0897
Brugia malayi Cation transporter family protein 0.0012 0.003 0.0099
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.003 0.0023
Echinococcus multilocularis smad 0.0018 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0375 0.0368
Echinococcus multilocularis neuropeptide s receptor 0.0012 0.0025 0.0017
Onchocerca volvulus 0.0058 0.0555 0.1898
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Onchocerca volvulus 0.0046 0.0412 0.1404
Mycobacterium ulcerans integral membrane protein 0.0019 0.0103 0.0563
Onchocerca volvulus 0.0012 0.0025 0.0077
Loa Loa (eye worm) RNA binding protein 0.0074 0.0736 0.0982
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0052 0.0481 0.1575
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0025 0.0022
Plasmodium falciparum protease, putative 0.0019 0.0103 0.1378
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0041 0.0039
Brugia malayi DIX domain containing protein 0.001 0.0008 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0375 0.1229
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.014 0.0309
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0495 0.125
Schistosoma mansoni hypothetical protein 0.008 0.0802 0.08
Schistosoma mansoni nuclear hormone receptor 0.002 0.0118 0.0116
Brugia malayi transcription factor E74 isoform 0.001 0.0008 0.0026
Loa Loa (eye worm) importin-beta domain-containing protein 0.0012 0.0024 0.0031
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0081 0.0266
Echinococcus granulosus caspase 2 0.01 0.1032 0.1025
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0158 0.047
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0368 0.0361
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0118 0.0398
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Loa Loa (eye worm) transcription factor SMAD2 0.0259 0.284 0.3788
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0375 0.0368
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0108 0.0101
Brugia malayi neuropeptide F receptor 0.0012 0.0025 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Echinococcus multilocularis GPCR, family 2 0.0034 0.0279 0.0271
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0041 0.0034
Schistosoma mansoni hypothetical protein 0.0013 0.0041 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0477 0.1377
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Schistosoma mansoni DNA ligase IV 0.0021 0.0132 0.013
Brugia malayi ORL1-like opioid receptor 0.0012 0.0025 0.0081
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0451 0.1132
Schistosoma mansoni adenoreceptor 0.0012 0.0025 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0802 0.2061
Echinococcus granulosus acetylcholinesterase 0.0271 0.2983 0.2977
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0279 0.0272
Trypanosoma brucei metacaspase MCA2 0.0052 0.0481 0.1389
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0279 0.0272
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0423 0.1059
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.1121 0.3673
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.001 0.0008 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0112 0.1162 0.3474
Leishmania major DNA polymerase eta, putative 0.0017 0.008 0.0235
Schistosoma mansoni smad1 5 8 and 0.0018 0.009 0.0088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0279 0.0272
Onchocerca volvulus 0.0046 0.0412 0.1404
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0118 0.0387
Brugia malayi Cation transporter family protein 0.0012 0.003 0.0099
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0266 0.2917 0.3891
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0029 0.0222 0.0625
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis bloom syndrome protein 0.0053 0.0495 0.0488
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0375 0.1229
Echinococcus granulosus microtubule associated protein 2 0.081 0.9121 0.912
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0025 0.0033
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.003 0.0023
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0041 0.0047
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.008 0.0171
Schistosoma mansoni smad1 5 8 and 0.0018 0.009 0.0088
Brugia malayi RE15519p 0.0012 0.0025 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0099 0.0228
Onchocerca volvulus 0.002 0.0118 0.0398
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0025 0.0081
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0226 0.0615
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0015 0.0057 0.0055
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0041 0.0136
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0222 0.0527
Echinococcus granulosus jun protein 0.0099 0.1012 0.1005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.1121 0.1495
Giardia lamblia Kinase, PLK 0.0111 0.1153 0.2884
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0081 0.0079
Echinococcus multilocularis serotonin receptor 0.0134 0.142 0.1413
Giardia lamblia DINP protein human, muc B family 0.0068 0.0668 0.1581
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0025 0.0022
Brugia malayi Carboxylesterase family protein 0.0271 0.2983 0.9772
Schistosoma mansoni hypothetical protein 0.0057 0.0534 0.0532
Echinococcus granulosus lamin dm0 0.0058 0.0555 0.0548
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.1811 0.6204
Plasmodium vivax DNA repair protein REV1, putative 0.0017 0.008 0.1159
Echinococcus granulosus dna polymerase kappa 0.0112 0.1162 0.1155
Schistosoma mansoni nuclear hormone receptor 0.002 0.0118 0.0116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0118 0.0111
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0146 0.0138
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.006 0.0578 0.1685
Schistosoma mansoni elf1 0.001 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0158 0.021
Brugia malayi Muscleblind-like protein 0.0149 0.1583 0.5186
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0025 0.0017
Schistosoma mansoni caspase-3 (C14 family) 0.0137 0.1454 0.1452
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.071 0.0947
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0025 0.0081
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0041 0.0079
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0602 0.1757
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0039
Echinococcus multilocularis expressed conserved protein 0.0092 0.0938 0.0931
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Loa Loa (eye worm) hypothetical protein 0.0022 0.0139 0.0186
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.004 0.0339 0.5555
Entamoeba histolytica hypothetical protein 0.0014 0.0044 0.0087
Leishmania major mitochondrial DNA polymerase beta 0.03 0.3314 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Brugia malayi Bloom's syndrome protein homolog 0.0053 0.0495 0.1623
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0158 0.0866
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0375 0.0368
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.0802 0.0795
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0022
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.004 0.0339 0.0836
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0237 0.0316
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0099 0.0091
Entamoeba histolytica hypothetical protein 0.0113 0.1175 0.3071
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0423 0.0416
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0041 0.0047
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.151 0.4529
Brugia malayi DKFZp564C0469 protein 0.0021 0.0132 0.0433
Loa Loa (eye worm) hypothetical protein 0.0028 0.0211 0.0281
Echinococcus multilocularis CAAX prenyl protease 2 0.0091 0.0928 0.0921
Brugia malayi nuclear receptor NHR-67 0.002 0.0118 0.0387
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0081 0.0074
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0025 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0411 0.1027
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.009 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0375 0.1229
Loa Loa (eye worm) ACC-1 protein 0.0012 0.003 0.004
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.1005 0.2624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Brugia malayi Carboxylesterase family protein 0.0046 0.0412 0.1348
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0375 0.128
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0423 0.0416
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0375 0.1229
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0413 0.0551
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi Ets-domain containing protein 0.001 0.0008 0.0026
Echinococcus multilocularis chromobox protein 2 0.0013 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0237 0.0649
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0158 0.0517
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.009 0.0082
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0676 0.0668
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.001 0.0008 0.0019
Toxoplasma gondii HEAT repeat-containing protein 0.0012 0.0024 0.0102
Brugia malayi MH1 domain containing protein 0.0018 0.009 0.0294
Loa Loa (eye worm) hypothetical protein 0.0077 0.0763 0.1018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0025 0.0017
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0025 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0008 0.0026
Brugia malayi hypothetical protein 0.0014 0.0043 0.0141
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.014 0.0355
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0041 0.0307
Brugia malayi Serotonin receptor 0.0012 0.0025 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0423 0.0421
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0025 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0158 0.021
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.003 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0099 0.0132
Schistosoma mansoni opsin-like receptor 0.0012 0.0025 0.0022
Onchocerca volvulus Cell death protein 3 homolog 0.01 0.1032 0.3532
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.009 0.0487
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0025 0.0017
Brugia malayi MH2 domain containing protein 0.0018 0.009 0.0294
Brugia malayi RNA, U transporter 1 0.0178 0.1916 0.6276
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.003 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Leishmania major DNA polymerase kappa, putative 0.0068 0.0668 0.201
Loa Loa (eye worm) DIX domain-containing protein 0.001 0.0008 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0375 0.1229
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0099 0.0096
Echinococcus multilocularis serotonin receptor 0.0134 0.142 0.1413
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0237 0.0423
Echinococcus multilocularis Chromo domain 0.0013 0.0041 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.014 0.2183
Echinococcus granulosus expressed conserved protein 0.0092 0.0938 0.0931
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.003 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.0821 0.1095
Plasmodium falciparum importin beta, putative 0.0063 0.0602 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0375 0.0373
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0158 0.0386
Onchocerca volvulus 0.0046 0.0412 0.1404
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Echinococcus granulosus Smad4 0.0018 0.009 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0025 0.0022
Schistosoma mansoni tsg101-related 0.0055 0.0522 0.052
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0029 0.0222 0.0297
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0054 0.0505 0.0673
Toxoplasma gondii hypothetical protein 0.0019 0.0103 0.061
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0025 0.0022
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0132 0.1878
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0375 0.05
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0026 0.0006
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.003 0.0099
Echinococcus multilocularis dnaJ subfamily B 0.0887 1 1
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.037 0.1073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0375 0.1229
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0041 0.0505
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0222 0.0527
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0467 0.1174
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.0012 0.0025 0.0022
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0025 0.0022
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0111 0.1153 0.1146
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0025 0.0017
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0047 0.0422 0.6889
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0412 0.0404
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0072 0.0706 0.3444
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0041 0.0215
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.1175 0.1173
Echinococcus granulosus sex peptide receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0118 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Schistosoma mansoni calcium-activated potassium channel 0.0153 0.1633 0.1631
Onchocerca volvulus 0.0012 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0051 0.0476 0.0635
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0716 0.0709
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0375 0.05
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0148 0.1574 0.1567
Loa Loa (eye worm) hypothetical protein 0.0091 0.0928 0.1238
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.0041 0.0351 0.0349
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0118 0.0387
Brugia malayi hypothetical protein 0.0082 0.0819 0.2684
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0375 0.0368
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0676 0.0668
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0279 0.0271
Brugia malayi Ets-domain containing protein 0.0072 0.071 0.2326
Echinococcus multilocularis jun protein 0.0099 0.1012 0.1005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0025 0.0017
Schistosoma mansoni amine GPCR 0.0012 0.0025 0.0022
Brugia malayi isocitrate dehydrogenase 0.0034 0.0279 0.0915
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0091 0.0928 0.2796
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0158 0.0866
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Echinococcus multilocularis snurportin 1 0.0667 0.7498 0.7496
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0375 0.0373
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0375 0.0368
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.014 0.0133
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0158 0.0866
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0025 0.0017
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.014 0.0769
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0118 0.0111
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.003 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0476 0.1393
Schistosoma mansoni nuclear receptor 0.002 0.0118 0.0116
Schistosoma mansoni calcium-activated potassium channel 0.0145 0.1548 0.1546
Echinococcus granulosus Ankyrin 0.0017 0.0083 0.0075
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0279 0.0373
Loa Loa (eye worm) carboxylesterase 0.0046 0.0412 0.0549
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.014 0.0187
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.003 0.004
Trypanosoma brucei chrX additional, unordered contigs 0.0017 0.008 0.0171
Trypanosoma brucei polo-like protein kinase 0.0111 0.1153 0.3431
Loa Loa (eye worm) hypothetical protein 0.0271 0.2983 0.3978
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Entamoeba histolytica recQ family helicase, putative 0.0028 0.0213 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Loa Loa (eye worm) hypothetical protein 0.0018 0.009 0.012
Echinococcus granulosus allatostatin A receptor 0.0012 0.0025 0.0017
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0279 0.0777
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0025 0.0022
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0213 0.0596
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0118 0.0111
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0099 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0112 0.1162 0.3474
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0423 0.1387
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0091 0.0928 0.2764
Giardia lamblia Fructose-bisphosphate aldolase 0.0343 0.3799 1
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0048 0.044 0.0587
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0041 0.0135
Echinococcus multilocularis Ankyrin 0.0017 0.0083 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0226 0.3635
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0375 0.0373
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0736 0.0734
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Echinococcus multilocularis cpg binding protein 0.0066 0.0639 0.0632
Onchocerca volvulus 0.0057 0.0534 0.1825
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.003 0.004
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0132 0.2044
Loa Loa (eye worm) hypothetical protein 0.0036 0.0298 0.0398
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0025 0.0022
Onchocerca volvulus 0.0012 0.0025 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0481 0.121
Loa Loa (eye worm) inositol-1 0.008 0.0802 0.1069
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0279 0.0915
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0132 0.0288
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.014 0.0162
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0802 0.2382
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0041 0.0047
Echinococcus multilocularis somatostatin receptor 0.0012 0.0025 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0079 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0411 0.1027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Loa Loa (eye worm) hypothetical protein 0.0134 0.142 0.1894
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Schistosoma mansoni coup transcription factor 0.0043 0.0375 0.0373
Mycobacterium ulcerans hypothetical protein 0.0024 0.0158 0.0866
Schistosoma mansoni lamin 0.0058 0.0555 0.0553
Brugia malayi jmjC domain containing protein 0.0018 0.0099 0.0323
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0081 0.0271
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0063
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0146 0.0144
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0413 0.2591
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.003 0.0099
Echinococcus granulosus carboxylesterase 5A 0.0271 0.2983 0.2977
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0821 0.2112
Treponema pallidum hypothetical protein 0.0019 0.0103 0.0229
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0375 0.1229
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0279 0.0272
Brugia malayi hypothetical protein 0.0021 0.0132 0.0433
Echinococcus granulosus CAAX prenyl protease 2 0.0091 0.0928 0.0921
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0026 0.0186 0.0495
Schistosoma mansoni tsg101-related 0.0068 0.0664 0.0662
Schistosoma mansoni ets-related 0.001 0.0008 0.0006
Brugia malayi hypothetical protein 0.0019 0.0107 0.0349
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0082 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1914 0.5007
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0411 0.1403
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0555 0.0741
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Giardia lamblia Hypothetical protein 0.0091 0.0928 0.228
Trypanosoma cruzi metacaspase 5, putative 0.0052 0.0481 0.1408
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0139 0.0132
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0375 0.128
Brugia malayi nuclear hormone receptor 0.0043 0.0375 0.1229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0375 0.0373
Echinococcus multilocularis caspase 2 0.01 0.1032 0.1025
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.003 0.0023
Trypanosoma brucei unspecified product 0.0037 0.0314 0.0881
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0132 0.0318
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0118 0.0387
Echinococcus granulosus translational activator gcn1 0.0012 0.0024 0.0016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0375 0.0368
Schistosoma mansoni chromobox protein 0.0013 0.0041 0.0039
Brugia malayi MH2 domain containing protein 0.0018 0.009 0.0294
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0412 0.2279
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0041 0.0506
Echinococcus granulosus biogenic amine 5HT receptor 0.0134 0.142 0.1413
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0081 0.0108
Toxoplasma gondii hypothetical protein 0.0019 0.0103 0.061
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0237 0.0566
Echinococcus multilocularis lamin 0.0058 0.0555 0.0548
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0244 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0736 0.0729
Echinococcus multilocularis neuropeptide receptor A26 0.0012 0.0025 0.0017
Schistosoma mansoni Smad4 0.0018 0.009 0.0088
Entamoeba histolytica HEAT repeat domain containing protein 0.0012 0.0024 0.0032
Echinococcus multilocularis nAChR subunit 0.0012 0.003 0.0023
Echinococcus granulosus bloom syndrome protein 0.0053 0.0495 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0279 0.4425
Echinococcus multilocularis protein arginine N methyltransferase 8 0.004 0.0339 0.0332
Treponema pallidum fructose-bisphosphate aldolase 0.0343 0.3799 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.0413 0.6744
Loa Loa (eye worm) hypothetical protein 0.0017 0.0083 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0091 0.0928 0.0926
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0025 0.0017
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.071 0.0703
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0025 0.0017
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0025 0.0081
Echinococcus granulosus neuropeptide receptor A26 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0266 0.2917 0.3891
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.004 0.0339 0.0836
Brugia malayi Serotonin receptor 0.0012 0.0025 0.0081
Brugia malayi Protein kinase domain containing protein 0.0017 0.0085 0.0279
Trichomonas vaginalis hypothetical protein 0.004 0.0342 0.0843
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0736 0.0982
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0025 0.0017
Plasmodium falciparum polypyrimidine tract-binding protein, putative 0.0012 0.0029 0.0093
Trichomonas vaginalis DNA polymerase eta, putative 0.0112 0.1162 0.3016
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0008 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Schistosoma mansoni protein arginine N-methyltransferase 1 0.004 0.0339 0.0337
Brugia malayi nuclear receptor NHR-88 0.002 0.0118 0.0387
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0099 0.0581
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi Ets-domain containing protein 0.0072 0.071 0.2326
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Echinococcus granulosus neuropeptide receptor 0.0012 0.0025 0.0017
Trypanosoma cruzi arginine N-methyltransferase, putative 0.006 0.0578 0.1703
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0003
Mycobacterium ulcerans hypothetical protein 0.0017 0.008 0.0433
Brugia malayi G-protein coupled receptor 0.0012 0.0025 0.0081
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0279 0.0272
Trypanosoma brucei Metacaspase-4 0.0052 0.0481 0.1389
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0736 0.2412
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0412 0.2279
Schistosoma mansoni protein arginine N-methyltransferase 1 0.004 0.0339 0.0337
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Echinococcus granulosus dna polymerase eta 0.0054 0.0505 0.0498
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0082 0.008
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.006 0.0578 0.1495
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0025 0.0017
Onchocerca volvulus 0.0062 0.0599 0.2046
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0099 0.0096
Brugia malayi Protein cec-1. 0.0013 0.0041 0.0135
Echinococcus granulosus chromobox protein 2 0.0013 0.0041 0.0034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Toxoplasma gondii HEAT repeat-containing protein 0.0063 0.0602 0.3793
Echinococcus granulosus small conductance calcium activated potassium 0.0153 0.1633 0.1626
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.004 0.0339 0.2118
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0802 0.2382
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0874 0.0867
Brugia malayi nuclear receptor RXR 0.0023 0.0146 0.0478
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0158 0.047
Loa Loa (eye worm) hypothetical protein 0.0162 0.1733 0.2311
Schistosoma mansoni topbp1 0.0021 0.0132 0.013
Brugia malayi TAR-binding protein 0.0074 0.0736 0.2412
Schistosoma mansoni ets-related 0.0219 0.2382 0.2381
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.014 0.046
Loa Loa (eye worm) acetylcholinesterase 1 0.0271 0.2983 0.3978
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0736 0.0734
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0111 0.1153 0.1537
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0412 0.0404
Schistosoma mansoni regulator of G protein signaling 0.001 0.0008 0.0005
Echinococcus granulosus neuroligin 0.0046 0.0412 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Brugia malayi AKH receptor 0.0012 0.0025 0.0081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0108 0.0145
Schistosoma mansoni amine GPCR 0.0012 0.0025 0.0022
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0081 0.0074
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0072 0.0706 0.3918
Loa Loa (eye worm) hypothetical protein 0.0108 0.1121 0.1495
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Schistosoma mansoni hypothetical protein 0.0113 0.1175 0.1173
Leishmania major hypothetical protein, conserved 0.003 0.0226 0.0676
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0016 0.0014
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0132 0.014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0025 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0477 0.1377
Brugia malayi Heterochromatin protein 1 0.0082 0.0821 0.2689
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0025 0.0017
Loa Loa (eye worm) globin family protein 0.001 0.0002 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.037 0.1073
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.1153 0.1151
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0025 0.0033
Echinococcus multilocularis muscleblind protein 1 0.0149 0.1583 0.1577
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0025 0.0033
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0451 0.154
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0099 0.1012 0.1005
Echinococcus granulosus fmrfamide receptor 0.0012 0.0025 0.0017
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0213 0.0575
Echinococcus multilocularis geminin 0.0367 0.4078 0.4073
Onchocerca volvulus Huntingtin homolog 0.0266 0.2917 1
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.1005 0.0999
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.9086 0.9085
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0139 0.0456
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0041 0.0216
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0025 0.0017
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.003 0.0023
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0412 0.041
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.1153 0.3445
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0423 0.0416
Toxoplasma gondii exonuclease III APE 0.0022 0.014 0.0848
Schistosoma mansoni hypothetical protein 0.0367 0.4078 0.4076
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0118 0.0111
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.014 0.0769
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.1811 0.4733
Brugia malayi serine/threonine-protein kinase plk-2 0.0111 0.1153 0.3776
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0213 0.0636
Onchocerca volvulus 0.0012 0.0025 0.0077
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0052 0.0481 0.121
Schistosoma mansoni hypothetical protein 0.0887 1 1
Trypanosoma brucei CAAX amino terminal protease, putative 0.0091 0.0928 0.2749
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0375 0.0373
Schistosoma mansoni inositol monophosphatase 0.008 0.0802 0.08
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0099 0.1298
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0099 0.0091
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0599 0.0799
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0158 0.0386
Echinococcus granulosus inositol monophosphatase 1 0.008 0.0802 0.0795
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0375 0.05
Echinococcus granulosus protein arginine N methyltransferase 7 0.0029 0.0222 0.0215
Echinococcus granulosus importin subunit beta 1 0.0063 0.0602 0.0594
Toxoplasma gondii bicoid-interacting protein BIN3 0.0029 0.0222 0.1372
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0676 0.0668
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Brugia malayi conserved hypotetical protein 0.002 0.0118 0.0387
Mycobacterium ulcerans hypothetical protein 0.0019 0.0103 0.0563
Echinococcus multilocularis lamin dm0 0.0058 0.0555 0.0548
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0008 0.0025
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0132 0.0795
Trypanosoma brucei unspecified product 0.0037 0.0314 0.0881
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.1485 0.1478
Loa Loa (eye worm) hypothetical protein 0.0134 0.142 0.1894
Brugia malayi GnHR receptor homolog 0.0012 0.0025 0.0081
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0279 0.0777
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0068 0.0668 0.3705
Schistosoma mansoni hypothetical protein 0.0034 0.0279 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Toxoplasma gondii HEAT repeat-containing protein 0.0012 0.0024 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1914 0.5007
Trypanosoma cruzi metacaspase, putative 0.0052 0.0481 0.1408
Echinococcus granulosus neuropeptide s receptor 0.0012 0.0025 0.0017
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.009 0.012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0423 0.1234
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0375 0.0373
Echinococcus granulosus GPCR family 2 0.0034 0.0279 0.0271
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0413 0.1354
Echinococcus multilocularis survival motor neuron protein 1 0.0277 0.3052 0.3047
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Leishmania major DNA damage repair protein, putative 0.0017 0.008 0.0235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0041 0.0047
Trypanosoma brucei mitochondrial DNA polymerase beta 0.03 0.3314 1
Schistosoma mansoni acetylcholinesterase 0.0046 0.0412 0.041
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0412 0.041
Brugia malayi Cell death protein 3 precursor 0.01 0.1032 0.338
Brugia malayi hypothetical protein 0.006 0.0578 0.1893
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0279 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Echinococcus granulosus acetylcholinesterase 0.0271 0.2983 0.2977
Onchocerca volvulus 0.0012 0.0025 0.0077
Schistosoma mansoni neuropeptide receptor 0.0012 0.0025 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0069 0.0673 0.0898
Onchocerca volvulus 0.0012 0.0025 0.0077
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0423 0.0416
Loa Loa (eye worm) hypothetical protein 0.0034 0.0279 0.0372
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Echinococcus granulosus geminin 0.0367 0.4078 0.4073
Loa Loa (eye worm) hypothetical protein 0.0074 0.0737 0.0983
Brugia malayi polk-prov protein 0.0074 0.0737 0.2416
Mycobacterium ulcerans DNA polymerase IV 0.0112 0.1162 0.6456
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0091 0.0928 0.2396
Trypanosoma brucei metacaspase 0.0052 0.0481 0.1389
Loa Loa (eye worm) carboxylesterase 0.0046 0.0412 0.0549
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Onchocerca volvulus 0.0012 0.0025 0.0077
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.008 0.0171
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0158 0.0153
Brugia malayi M-phase phosphoprotein, mpp8 0.0013 0.0041 0.0135
Brugia malayi Globin family protein 0.001 0.0002 0.0007
Echinococcus granulosus Regulator of differentiation 1 0.0012 0.0029 0.0021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.003 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0375 0.0373
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0244 0.0242
Onchocerca volvulus 0.0013 0.0041 0.0134
Brugia malayi Dopamine receptor 0.0012 0.0025 0.0081
Trypanosoma cruzi polypyrimidine tract-binding protein, putative 0.0012 0.0029 0.0038
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0128 0.0276
Onchocerca volvulus 0.0012 0.0025 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0025 0.0017
Echinococcus granulosus phd:f box containing protein 0.0018 0.0099 0.0091
Brugia malayi Cation transporter family protein 0.0012 0.003 0.0099
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0081 0.0074
Plasmodium falciparum heterochromatin protein 1 0.0013 0.0041 0.0307
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0025 0.0022
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.0413 0.681
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0025 0.0077
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0139 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0375 0.1229
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0467 0.1174
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Brugia malayi Smad1 0.0018 0.009 0.0294
Onchocerca volvulus 0.0012 0.0025 0.0077
Entamoeba histolytica hypothetical protein 0.0051 0.0467 0.1202
Schistosoma mansoni polypyrimidine tract binding protein 0.0012 0.0029 0.0027
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0031 0.0243 0.1503
Echinococcus multilocularis nibrin 0.0021 0.0132 0.0125
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0118 0.0158
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.0802 0.4451
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0505 0.1654
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.037 0.1054
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Plasmodium falciparum metacaspase-like protein 0.0052 0.0481 0.7907
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0146 0.0138
Schistosoma mansoni ets 0.001 0.0008 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0375 0.0368
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Trypanosoma cruzi arginine N-methyltransferase, putative 0.006 0.0578 0.1703
Schistosoma mansoni ap endonuclease 0.0022 0.014 0.0138
Onchocerca volvulus 0.0036 0.0298 0.1016
Echinococcus granulosus orexin receptor type 2 0.0012 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0158 0.021
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.003 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.014 0.0376
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0555 0.182
Trypanosoma brucei DNA polymerase kappa, putative 0.0112 0.1162 0.346
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0057 0.0534 0.175
Echinococcus granulosus muscleblind protein 0.0149 0.1583 0.1577
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.003 0.0028
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0146 0.0144
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0412 0.0404
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0065 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0737 0.2169
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0103 0.0242
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0279 0.0271
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0054 0.0505 0.0503
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.009 0.012
Brugia malayi Carm1-pending protein 0.0148 0.1574 0.5155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0099 0.0132
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0082 0.0074
Loa Loa (eye worm) hypothetical protein 0.0082 0.0819 0.1092
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.0802 0.2087
Entamoeba histolytica hypothetical protein 0.0013 0.0041 0.0079
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0029 0.0222 0.0557
Brugia malayi hypothetical protein 0.0012 0.0029 0.0095
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0226 0.1394
Onchocerca volvulus 0.0012 0.003 0.0096
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0008 0.0025
Leishmania major hypothetical protein, conserved 0.0026 0.0186 0.0556
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0025 0.0022
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.003 0.0023
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0068 0.0668 0.201
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0375 0.0373
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0716 0.0955
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Brugia malayi ecdysone receptor 0.002 0.0118 0.0387
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0041 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Brugia malayi jmjC domain containing protein 0.0018 0.0099 0.0323
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0025 0.0081
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.1175 0.1168
Brugia malayi nuclear hormone receptor 0.002 0.0118 0.0387
Schistosoma mansoni chromobox protein 0.0013 0.0041 0.0039
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0039
Schistosoma mansoni opsin-like receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.1153 0.3445
Trypanosoma brucei unspecified product 0.0097 0.0999 0.2964
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0099 0.1012 0.1005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0118 0.0111
Brugia malayi G protein-coupled receptor 0.0012 0.0025 0.0081
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.1005 0.3294
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0036 0.0294 0.1829
Schistosoma mansoni dishevelled 0.001 0.0008 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Echinococcus granulosus survival motor neuron protein 1 0.0277 0.3052 0.3047
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0132 0.0351
Schistosoma mansoni blooms syndrome DNA helicase 0.0042 0.0368 0.0366
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Echinococcus granulosus tar DNA binding protein 0.0074 0.0736 0.0729
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.003 0.0023
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0413 0.1185
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Trichomonas vaginalis helicase, putative 0.0014 0.005 0.0069
Loa Loa (eye worm) MH2 domain-containing protein 0.0259 0.284 0.3788
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0375 0.0368
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0505 0.1462
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0065 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.009 0.012
Echinococcus multilocularis transportin 1 0.0012 0.0024 0.0016
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.151 0.4517
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0139 0.0132
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.1234 0.783
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0044 0.0055
Brugia malayi topoisomerase 0.0021 0.0132 0.0433
Brugia malayi hypothetical protein 0.0266 0.2917 0.9557
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0137 0.1454 0.1447
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0132 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0375 0.1229
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0029 0.0222 0.1372
Loa Loa (eye worm) hypothetical protein 0.003 0.0226 0.0301
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0111 0.1153 0.3473
Schistosoma mansoni patched 1 0.0042 0.0368 0.0366
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0025 0.0017
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.008 0.0193
Loa Loa (eye worm) hypothetical protein 0.0062 0.0591 0.0788
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0375 0.0368
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.001 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.0041 0.0351 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.003 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.0112 0.1162 0.346
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0802 0.2365
Trypanosoma brucei metacaspase 5, putative 0.0052 0.0481 0.1389
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0505 0.1481
Schistosoma mansoni cpg binding protein 0.0062 0.0599 0.0597
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0132 0.0723
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0279 0.0277
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0555 0.0741
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0132 0.0288
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Schistosoma mansoni importin beta-1 0.0063 0.0602 0.06
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.008 0.0462
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0029 0.0222 0.0625
Schistosoma mansoni protein arginine n-methyltransferase 0.0148 0.1574 0.1572
Onchocerca volvulus 0.0012 0.003 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0477 0.1377
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2818 0.7401
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0667 0.7498 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.0044 0.0085
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0237 0.023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0802 0.2061
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0016 0.0056
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0505 0.1654
Trichomonas vaginalis DNA helicase recq, putative 0.0028 0.0213 0.0501
Onchocerca volvulus Huntingtin homolog 0.0266 0.2917 1
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0029 0.0222 0.0604
Chlamydia trachomatis DNA ligase 0.0021 0.0132 1
Brugia malayi nuclear receptor RXR 0.002 0.0118 0.0387
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0025 0.0017
Brugia malayi ecdysteroid receptor 0.0043 0.0375 0.1229
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0026 0.0006
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0237 0.0669
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0025 0.0017
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0055 0.0522 0.1347
Echinococcus granulosus hypothetical protein 0.0012 0.0025 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Loa Loa (eye worm) hypothetical protein 0.0043 0.0375 0.05
Onchocerca volvulus 0.0012 0.003 0.0096
Echinococcus multilocularis neuroligin 0.0046 0.0412 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0112 0.1162 0.3474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0176
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Schistosoma mansoni hypothetical protein 0.0041 0.0351 0.0349
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0279 0.0271
Leishmania major arginine N-methyltransferase-like protein 0.0031 0.0244 0.0731
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0139 0.084
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Onchocerca volvulus 0.0012 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Echinococcus granulosus lamin 0.0058 0.0555 0.0548
Loa Loa (eye worm) Smad1 0.0018 0.009 0.012
Brugia malayi chromobox protein homolog 3 0.0046 0.0411 0.1347
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0412 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0375 0.1229
Trypanosoma cruzi metacaspase, putative 0.0052 0.0481 0.1408
Schistosoma mansoni ran 0.0046 0.0413 0.0411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Loa Loa (eye worm) Carm1-pending protein 0.0148 0.1574 0.2099
Schistosoma mansoni intermediate filament proteins 0.0058 0.0555 0.0553
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0025 0.0017
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0412 0.041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0158 0.0386
Brugia malayi hypothetical protein 0.0077 0.0771 0.2526
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0025 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0505 0.2797
Trypanosoma brucei Double RNA-binding domain containing protein 4 0.0012 0.0029 0.0016
Brugia malayi Carboxylesterase family protein 0.0271 0.2983 0.9772
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Loa Loa (eye worm) globin family protein 0.001 0.0002 0.0003
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0132 0.033
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0731 0.2396
Brugia malayi Carboxylesterase family protein 0.0046 0.0412 0.1348
Entamoeba histolytica serine/threonine protein kinase, putative 0.0111 0.1153 0.3013
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.1153 0.299
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0222 0.0527
Brugia malayi Carboxylesterase family protein 0.0046 0.0412 0.1348
Brugia malayi larval opioid receptor 0.0012 0.0025 0.0081
Schistosoma mansoni amine GPCR 0.0012 0.0025 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0279 0.1735
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0211 0.0203
Schistosoma mansoni nuclear receptor 0.002 0.0118 0.0116
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0025 0.0017
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.003 0.004
Entamoeba histolytica hypothetical protein 0.0013 0.0041 0.0079
Echinococcus multilocularis protein arginine methyltransferase 0.004 0.0339 0.0332
Schistosoma mansoni biogenic amine receptor 0.0012 0.0025 0.0022
Leishmania major DNA polymerase kappa, putative 0.0017 0.008 0.0235
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.3314 1
Trypanosoma cruzi metacaspase 5, putative 0.0052 0.0481 0.1408
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0055
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0103 0.0563
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0246 0.0328
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0412 0.2279
Schistosoma mansoni hypothetical protein 0.0029 0.0222 0.022
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.071 0.0703
Brugia malayi Globin family protein 0.001 0.0002 0.0007
Onchocerca volvulus 0.0012 0.0025 0.0077
Schistosoma mansoni hypothetical protein 0.0041 0.0351 0.0349
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.003 0.004
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0375 0.128
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0025 0.0017
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0412 0.2279
Onchocerca volvulus Putative nachr subunit 0.0012 0.003 0.0096
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.003 0.004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0423 0.1272
Loa Loa (eye worm) hypothetical protein 0.0047 0.0423 0.0565
Entamoeba histolytica hypothetical protein 0.0113 0.1175 0.3071
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0054 0.0505 0.0498
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.1121 0.3673
Schistosoma mansoni amine GPCR 0.0012 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0212 0.2304 0.3073
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0025 0.0017
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0041 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Brugia malayi Dopamine receptor protein 2 0.0012 0.0025 0.0081
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0716 0.0714
Schistosoma mansoni hypothetical protein 0.001 0.0008 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0375 0.05
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0279 0.0272
Brugia malayi Dopamine receptor protein 1 0.0012 0.0025 0.0081
Entamoeba histolytica hypothetical protein 0.0113 0.1175 0.3071
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.3314 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0158 0.0517
Brugia malayi hypothetical protein 0.0012 0.0025 0.0081
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Onchocerca volvulus 0.0058 0.0555 0.1898
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.009 0.0082
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.008 0.0802 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.003 0.0099
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.1485 0.1478
Brugia malayi hypothetical protein 0.0113 0.1175 0.3848
Loa Loa (eye worm) hypothetical protein 0.0277 0.3052 0.4071
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0025 0.0033
Brugia malayi jmjC domain containing protein 0.0073 0.0716 0.2346
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0198 0.0264
Echinococcus multilocularis importin 5 0.0012 0.0024 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0736 0.0734
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0025 0.0017
Toxoplasma gondii hypothetical protein 0.0048 0.0441 0.2769
Echinococcus granulosus death domain containing protein 0.0017 0.0081 0.0074
Onchocerca volvulus 0.001 0.0008 0.0019
Loa Loa (eye worm) ACC-1 protein 0.0012 0.003 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0423 0.1059
Onchocerca volvulus 0.002 0.0118 0.0398
Loa Loa (eye worm) hypothetical protein 0.0042 0.0368 0.0491
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0052 0.0481 0.302
Brugia malayi Death domain containing protein 0.0017 0.0081 0.0266
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0375 0.0368
Echinococcus multilocularis importin subunit beta 1 0.0063 0.0602 0.0594
Schistosoma mansoni nAChR subunit 0.0012 0.003 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0065 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0158 0.047
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.009 0.0487
Echinococcus granulosus chromobox protein 1 0.0082 0.0821 0.0814
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0481 0.7949
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0029 0.0222 0.0215
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0158 0.0866
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0467 0.1366
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0118 0.0158
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0821 0.2112
Onchocerca volvulus 0.0043 0.0375 0.128
Loa Loa (eye worm) hypothetical protein 0.0098 0.1005 0.1341
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0025 0.0033
Loa Loa (eye worm) kap beta 3 protein 0.0012 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0194
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0065 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0423 0.0924
Schistosoma mansoni topbp1 0.0021 0.0132 0.013
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0413 0.0406
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0025 0.0022
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0139 0.2
Schistosoma mansoni gabp alpha 0.0072 0.071 0.0708
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0025 0.0017
Entamoeba histolytica hypothetical protein 0.0113 0.1175 0.3071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0375 0.0368
Onchocerca volvulus 0.0012 0.0025 0.0077
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0029 0.0222 0.0665
Entamoeba histolytica hypothetical protein 0.0014 0.0044 0.0087
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0211 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0343 0.3799 1
Echinococcus granulosus protein arginine N methyltransferase 8 0.004 0.0339 0.0332
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.009 0.1324
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0259 0.0623
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0025 0.0033
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0052 0.0481 0.302
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0226 0.0636
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0132 0.0288
Brugia malayi Fli-1 protein 0.0219 0.2382 0.7805
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0139 0.0132
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0423 0.1234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0202 0.0473
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0025 0.0017
Schistosoma mansoni cpg binding protein 0.0066 0.0639 0.0637
Onchocerca volvulus 0.0046 0.0412 0.1404
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0033
Entamoeba histolytica hypothetical protein 0.0013 0.0041 0.0079
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0108 0.0101
Loa Loa (eye worm) hypothetical protein 0.0046 0.0412 0.0549
Plasmodium vivax importin-beta 2, putative 0.0063 0.0602 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.003 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0423 0.1059

Activities

Activity type Activity value Assay description Source Reference
Active dose (functional) = 3 mg kg-1 Inhibition of oubain induced arrythmia in the dog. ChEMBL. 2754714
Distribution coefficient = 0.78 Distribution coefficient of compound was determined in octanol-water system ChEMBL. 2754714
ED50 (functional) = 7 ug ml-1 Inhibition of acetylstrophantidin induced arrythmiay in guinea pig isolated right atria. ChEMBL. 2754714
T1/2 (ADMET) = 36.1 min Biological half-life was evaluated in whole human blood ChEMBL. 2754714
T1/2 (ADMET) = 36.1 min Biological half-life was evaluated in whole human blood ChEMBL. 2754714

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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